What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Reinforcement learning model for optimizing dexmedetomidine dosing to prevent delirium in critically ill patients
- Authors
- Lee, H. Y. Chung, S. Hyeon, D. Yang, H. L. Lee, H. C. Ryu, H. G. Lee, H.
- Year
- 2024
- Journal
- NPJ Digit Med
- Abstract
Delirium can result in undesirable outcomes including increased length of stays and mortality in patients admitted to the intensive care unit (ICU). Dexmedetomidine has emerged for delirium prevention in these patients; however, optimal dosing is challenging. A reinforcement learning-based Artificial Intelligence model for Delirium prevention (AID) is proposed to optimize dexmedetomidine dosing. The model was developed and internally validated using 2416 patients (2531 ICU admissions) and externally validated on 270 patients (274 ICU admissions). The estimated performance return of the AID policy was higher than that of the clinicians’ policy in both derivation (0.390 95% confidence interval [CI] 0.361 to 0.420 vs. -0.051 95% CI -0.077 to -0.025) and external validation (0.186 95% CI 0.139 to 0.236 vs. -0.436 95% CI -0.474 to -0.402) cohorts. Our finding indicates that AID might support clinicians’ decision-making regarding dexmedetomidine dosing to prevent delirium in ICU patients, but further off-policy evaluation is required.
- PMID
PMID: 39557970
PMCID: PMC11574043
- Keywords
Delirium
ICU
Dexmedetomidine
Artificial Intelligence model for Delirium prevention
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study | Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. | Crit Care Explor | 2020 |
benzodiazepine |
| Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database | Sato, K. Mano, T. Iwata, A. Toda, T. | Biosci Trends | 2020 |
Adverse Drug Reaction Reporting Systems |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Non-pharmacological approaches in the prevention of delirium | Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. | European Geriatric Medicine | 2020 |
psychotropic agent |
| Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study | Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. | Medicina (Kaunas) | 2020 |
biomarker |
| Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
| Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta | Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. | Egypt Heart J | 2020 |
Aging |
| Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients | Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. | J Psychiatr Res | 2020 |
Aging |
| Major surgery induces acute changes in measured DNA methylation associated with immune response pathways | Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. | Sci Rep | 2020 | |
| Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period | Rostoft, S. Hamaker, M. E. | Eur J Surg Oncol | 2020 |
Cognition |
| The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review | Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. | Age Ageing | 2020 |
delirium |
| Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review | Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. | Crit Care Med | 2020 | |
| Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal | Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. | Minerva Anestesiol | 2020 | |
| Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic | Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. | Lancet Psychiatry | 2020 |
Coronavirus Infections/ complications |
| Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Acta Neuropsychiatr | 2020 |
anti-N-methyl-D-aspartate receptor encephalitis |
| Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Gen Hosp Psychiatry | 2020 |
Anti-NMDA receptor encephalitis |
| Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit | Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
| Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study | Rásky, É Stolz, E. Jagsch, C. | Neuropsychiatrie | 2020 |
article |
| Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital | Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F. | Aust Crit Care | 2020 |
Intensive care |
| Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery | Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C. | Journal of Alzheimer's Disease | 2020 |
aged |
| Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service | Quante, A. Schulz, K. Fissler, M. | Wiener Medizinische Wochenschrift | 2020 |
adult |
| Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis | Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W. | Cardiovasc Interv Ther | 2020 |
Delirium |
| A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer | Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L. | J Geriatr Oncol | 2020 |
Functional decline |
| Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study | Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G. | Eur J Anaesthesiol | 2020 | |
| Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease | Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F. | Brain Behav Immun | 2020 |
Alzheimer’s disease |
| Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria | Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M. | Infect Control Hosp Epidemiol | 2020 | |
| Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials | Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H. | J Cardiothorac Vasc Anesth | 2020 |
acute kidney injury |
| Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium | Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O. | Anesthesiology | 2020 | |
| Evaluating delirium outcomes among older adults in the surgical intensive care unit | Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. | Heart Lung | 2020 |
Critical care |
| Association between continuous deep sedation and survival time in terminally ill cancer patients | Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. | Support Care Cancer | 2020 |
Continuous deep sedation |
| Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study | Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. | J Clin Med | 2020 |
bilirubin |
| Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review | Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. | J Clin Neurosci | 2020 |
Cerebrovascular Disease |
| A prospective cohort study on predictors of mortality of delirium in an emergency observational unit | Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. | QJM | 2020 |
Acute confusional state |
| Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery | Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. | J Perianesth Nurs | 2020 |
anxiety |
| Association between fluid overload and delirium/coma in mechanically ventilated patients | Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. | Acute Med Surg | 2020 |
Brain dysfunction |
| Hallucinations after Cardiac Surgery: A Prospective Observational Study | Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. | Medicina (Kaunas) | 2020 |
cardiothoracic surgery |
| Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes | Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. | J Orthop Sci | 2020 | |
| Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study | Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. | J Stomatol Oral Maxillofac Surg | 2020 |
Dementia |
| Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function | Onoda, S. Kinoshita, M. Ariyoshi, Y. | J Craniofac Surg | 2020 | |
| Delirium: a missing piece in the COVID-19 pandemic puzzle | O'Hanlon, S. Inouye, S. K. | Age Ageing | 2020 |
Covid-19 |
| Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial | Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. | Am J Geriatr Psychiatry | 2020 |
Delirium |
| A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank | Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. | Alzheimers Dement | 2020 |
biomarkers |
| Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery | Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. | J Neurosurg Spine | 2020 |
ASD = adult spinal deformity |
| Communication with patients in post-traumatic confusional state: perception of rehabilitation staff | Nielsen, A. I. Power, E. Jensen, L. R. | Brain Injury | 2020 |
comprehension |
| Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system | Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. | Singapore Medical Journal | 2020 |
dexmedetomidine |
| Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis | Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. | J Clin Anesth | 2020 |
Cardiac complications |
| Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study | Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. | J Geriatr Oncol | 2020 |
Aged 80 and over |
| Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study | Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. | Anesthesia and Analgesia | 2020 |
adult |
| Development of a clinical score, PANDA, to predict delirium in stroke care unit | Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. | J Neurol Sci | 2020 |
Area under curve |
| Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study | Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. | Clinical Spine Surgery | 2020 |
adult |
| Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients | Naghibi, T. Shafigh, N. Mazloomzadeh, S. | Journal of Research in Medical Sciences | 2020 |
IRCT2015095536N5 |
| Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery | Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. | Crit Care | 2020 |
Anesthesia |
| Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? | Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. | British Journal of Clinical Pharmacology | 2020 |
quetiapine |
| Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() | Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. | Intern Med J | 2020 |
delirium |
| Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients | Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. | BMC Psychiatry | 2020 |
3d-cam |
| Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial | Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. | J Res Pharm Pract | 2020 |
Delirium |
| How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study | Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. | Supportive Care in Cancer | 2020 | |
| Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia | Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. | Journal of the American Medical Directors Association | 2020 |
intravenous catheter |
| Infection in older adults: a qualitative study of patient experience | Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. | Br J Gen Pract | 2020 |
aged |
| Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study | Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. | Eur J Clin Pharmacol | 2020 |
Aripiprazole |
| Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria | Moebs, I. Abeln, E. Siefert, A. Barak, Y. | Neurology and Therapy | 2020 |
adult |
| An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study | Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. | Osteoporos Int | 2020 |
Aged care |
| Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study | Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. | BMC Nurs | 2020 |
Co-design |
| Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis | Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. | Ann Palliat Med | 2020 |
Dexmedetomidine |
| Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium | Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. | Pediatr Crit Care Med | 2020 | |
| Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients | Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. | World J Psychiatry | 2020 |
Assessment |
| A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients | Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. | Aging & mental health | 2020 |
adult |
| Family intervention improves outcomes for patients with delirium: Systematic review and meta-analysis | McKenzie, J. Joy, A. | Australas J Ageing | 2020 |
caregivers |
| Effectiveness and Safety of Intrathecal Ziconotide: Final Results of the Patient Registry of Intrathecal Ziconotide Management (PRIZM) | McDowell, G. C. Saulino, M. F. Wallace, M. Grigsby, E. J. Rauck, R. L. Kim, P. Vanhove, G. F. Ryan, R. Huang, I. Z. Deer, T. | Pain medicine (Malden, Mass.) | 2020 |
adult |
| Management Effort for Delirium and Insomnia in Patients with Acute Ischemic Stroke (MEDIAS) Study | Matsuzono, K. Mashiko, T. Ozawa, T. Miura, K. Suzuki, M. Furuya, K. Ozawa, M. Anan, Y. Shimazaki, H. Koide, R. Tanaka, R. Fujimoto, S. | Psychiatry Clin Neurosci | 2020 | |
| High Prevalence of Oropharyngeal Dysphagia in Acutely Hospitalized Patients Aged 80 Years and Older | Mateos-Nozal, J. Montero-Errasquín, B. Sánchez García, E. Romero Rodríguez, E. Cruz-Jentoft, A. J. | J Am Med Dir Assoc | 2020 |
Dysphagia |
| Dexmedetomidine in medical cardiac intensive care units. Data from a multicenter prospective registry | Mateos Gaitan, R. Vicent, L. Rodriguez-Queralto, O. Lopez-de-Sa, E. Elorriaga, A. Pastor, G. Bañeras, J. Lorenzo, B. García-Rubira, J. C. Corbi, M. Ariza, A. Martínez-Sellés, M. | Int J Cardiol | 2020 |
Adverse effects |
| Myocardial Function in Patients With Radiation-Associated Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Layer-Specific Strain Analysis Study | Martinez, C. Cicenia, M. Sprynger, M. Postolache, A. Ilardi, F. Dulgheru, R. Radermecker, M. Esposito, G. Marechal, P. Marechal, V. Donis, N. Tridetti, J. Nguyen Trung, M. L. Sugimoto, T. Tsugu, T. Go, Y. Y. Coisne, A. Montaigne, D. Fattouch, K. Nchimi, A | JACC: Cardiovascular Imaging | 2020 |
CoreValve self-expandable biologic prosthesis |
| Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review | Manfredonia, F. Saturno, E. Lawley, A. Gasverde, S. Cavanna, A. E. | J Neurol Sci | 2020 |
Acute confusional state |
| Downstream consequences of abnormal cognitive screening in older adults seen pretreatment in a geriatric oncology clinic | Malik, U. Alam, Z. Loucks, A. Jin, R. Yokom, D. Watt, S. Berger, A. Romanovsky, L. Puts, M. Alibhai, S. M. H. | J Geriatr Oncol | 2020 |
Cognitive impairment |
| A Study of the Psychometric Properties of the "Stanford Proxy Test for Delirium" (S-PTD): A New Screening Tool for the Detection of Delirium | Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. | Psychosomatics | 2020 |
S-ptd |
| Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) | Mailhot, T. Darling, C. Ela, J. Malyuta, Y. Inouye, S. K. Saczynski, J. | J Am Geriatr Soc | 2020 |
Fam-cam |
| Frailty Is Associated With Postoperative Delirium But Not With Postoperative Cognitive Decline in Older Noncardiac Surgery Patients | Mahanna-Gabrielli, E. Zhang, K. Sieber, F. E. Lin, H. M. Liu, X. Sewell, M. Deiner, S. G. Boockvar, K. S. | Anesth Analg | 2020 |
Aged |
| 2019-NCoV: What every neurologist should know? | Mahajan, N. Singla, M. Singh, B. Sajja, V. Bansal, P. Paul, B. Goel, P. Midha, R. Bansal, R. Singh, G. | Annals of Indian Academy of Neurology | 2020 |
alanine aminotransferase |
| Age, Comorbidities and Fear of Fall: mortality predictors associated with fall-related fractures | Magdalini, V. Petros, I. Constantinos, T. Garyfalia, S. P. Emmanouil, P. Christos, K. George, K. Kalliopi, A. George, S. Symeon, H. P. | Maedica (Buchar) | 2020 | |
| Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness | Maas, M. B. Lizza, B. D. Kim, M. Abbott, S. M. Gendy, M. Reid, K. J. Zee, P. C. | Crit Care Med | 2020 | |
| Incidence and risk factors of delirium in icu patients | Ma, W. Zheng, J. Xu, S. Huo, Z. | International Journal of Clinical and Experimental Medicine | 2020 |
stomach tube |
| Age, preoperative higher serum cortisol levels, and lower serum acetylcholine levels predict delirium after percutaneous coronary intervention in acute coronary syndrome patients accompanied with renal dysfunction | Ma, J. Fan, M. Wang, Z. | Indian Journal of Psychiatry | 2020 |
IE33 |
| Non-Pharmacologic Multicomponent Interventions Preventing Delirium in Hospitalized People | Ludolph, P. Stoffers-Winterling, J. Kunzler, A. M. Rösch, R. Geschke, K. Vahl, C. F. Lieb, K. | J Am Geriatr Soc | 2020 |
delirium |
| Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women | Lu, G. W. Chou, Y. E. Jin, W. L. Su, X. B. | J Int Med Res | 2020 |
Translocator protein |
| Characteristics, Symptom Management, and Outcomes of 101 Patients With COVID-19 Referred for Hospital Palliative Care | Lovell, N. Maddocks, M. Etkind, S. N. Taylor, K. Carey, I. Vora, V. Marsh, L. Higginson, I. J. Prentice, W. Edmonds, P. Sleeman, K. E. | J Pain Symptom Manage | 2020 |
Covid-19 |
| Characterisation of ICU sleep by a commercially available activity tracker and its agreement with patient-perceived sleep quality | Louzon, P. Andrews, J. Torres, X. Pyles, E. Ali, M. Du, Y. Devlin, J. | BMJ Open Respir Res | 2020 |
equipment evaluations |
| Surgical treatment of hip fracture in centenarians: Complications and independent risk factors of death | López, Torres, II Sanz-Ruiz, P. Montero-Fernández, N. Chana, F. Serra-Rexach, J. A. Benjumea-Carrasco, A. Vaquero-Martín, J. | Injury | 2020 |
Centenarians |
| Long-term survival of femoral neck fracture patients aged over ninety years: Arthroplasty compared with nonoperative treatment | Liu, Y. Zhang, C. W. Zhao, X. D. | BMC Musculoskeletal Disorders | 2020 |
albumin |
| Subjective memory complaints predict poorer functional recovery during the first year following hip-fracture surgery among elderly adults | Liu, H. Y. Wang, H. P. Chen, C. Y. Wu, C. C. Hua, M. S. Lin, Y. E. Lin, Y. C. Shyu, Y. L. | Int J Geriatr Psychiatry | 2020 |
hip fracture |
| Delirium Severity Trajectories and Outcomes in ICU Patients: Defining a Dynamic Symptom Phenotype | Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. | Ann Am Thorac Soc | 2020 | |
| Early mobilisation of ventilated patients in the intensive care unit: A survey of critical care clinicians in an Australian tertiary hospital | Lin, F. Phelan, S. Chaboyer, W. Mitchell, M. | Aust Crit Care | 2020 |
Attitudes |
| Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study | Likhvantsev, V. V. Landoni, G. Grebenchikov, O. A. Ovezov, A. M. Skripkin, Y. V. Lembo, R. Gaevskiy, D. I. Tereshina, A. A. Yavorovskiy, A. G. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
| Derivation and Validation of a Risk Stratification System for Predicting Postoperative Cognitive Impairment | Liao, Y. Su, X. Ouyang, W. Li, L. Chen, S. Chou, J. Le, Y. | J Invest Surg | 2020 |
Postoperative cognitive dysfunction |
| Effects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis | Li, Y. Zhang, B. | Minerva Anestesiol | 2020 | |
| Prevalence, outcome and prognostic factors of neuropsychiatric systemic lupus erythematosus: A real world single center study | Li, X. Xiang, X. Sun, J. Liu, S. Liu, Y. Feng, L. Li, C. Li, Z. | Mod Rheumatol | 2020 |
Neuropsychiatric systemic lupus erythematosus |
| Postoperative Delirium Following Joint Replacement in Patients With Dementia in New South Wales, Australia: A State-Wide Retrospective Cohort Study | Li, X. Du, W. Parkinson, A. Glasgow, N. | Research in gerontological nursing | 2020 |
adult |
| Effect of dexmedetomidine on prevention of postoperative nausea and vomiting in pediatric strabismus surgery: a randomized controlled study | Li, S. Liu, T. Xia, J. Jia, J. Li, W. | BMC Ophthalmol | 2020 |
Dexmedetomidine |
| Toxicity and survival outcomes of autologous stem cell transplant in multiple myeloma patients with renal insufficiency: an institutional comparison between two eras | Li, A. Y. Atenafu, E. G. Bernard, R. S. Masih-Khan, E. Reece, D. Franke, N. Tiedemann, R. Prica, A. Trudel, S. Kukreti, V. Chen, C. I. | Bone Marrow Transplant | 2020 |