Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Efficacy and safety of perioperative melatonin for postoperative delirium in patients undergoing surgery: a systematic review and meta-analysis
Authors
Shin, H. W. Kwak, J. S. Choi, Y. J. Kim, J. W. You, H. S. Shin, H. J. Jang, Y. K.
Year
2024
Journal
J Int Med Res
Abstract

OBJECTIVE: To assess the efficacy and safety of perioperative melatonin and melatonin agonists in preventing postoperative delirium (POD). METHODS: We conducted a systematic search for randomized controlled trials (RCTs) published through December 2022. The primary outcome was efficacy based on the incidence of POD (POD-I). Secondary outcomes included efficacy and safety according to the length of hospital or intensive care unit stay, in-hospital mortality, and adverse events. Subgroup analyses of POD-I were based on the type and dose of drug (low- and high-dose melatonin, ramelteon), the postoperative period (early or late), and the type of surgery. RESULTS: In the analysis (16 RCTs, 1981 patients), POD-I was lower in the treatment group than in the control group (risk ratio [RR] = 0.57). POD-I was lower in the high-dose melatonin group than in the control group (RR = 0.41), whereas no benefit was observed in the low-dose melatonin and ramelteon groups. POD-I was lower in the melatonin group in the early postoperative period (RR = 0.35) and in patients undergoing cardiopulmonary surgery (RR = 0.54). CONCLUSION: Perioperative melatonin or melatonin agonist treatment suppressed POD without severe adverse events, particularly at higher doses, during the early postoperative period, and after cardiopulmonary surgery.

PMID

PMID: 38735057

PMCID: PMC11089947

Keywords

*Melatonin/therapeutic use/administration & dosage/adverse effects
Humans
*Postoperative Complications/prevention & control/drug therapy
*Delirium/prevention & control/drug therapy
Perioperative Care/methods
Indenes/therapeutic use/adverse effects/administration & dosage
Randomized Controlled Trials as Topic
Length of Stay
Treatment Outcome
Hospital Mortality
Delirium
melatonin
meta-analysis
perioperative treatment
postoperative
ramelteon
surgery

Page(s)
Issue

Search:
Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
International drive to illuminate delirium: A developing public health blueprint for action Khachaturian, A. S. Hayden, K. M. Devlin, J. W. Fleisher, L. A. Lock, S. L. Cunningham, C. Oh, E. S. Fong, T. G. Fick, D. M. Marcantonio, E. R. Iyengar, V. Rockwood, K. Kuchel, G. A. Eckenhoff, R. G. MacLullich, A. M. J. Jones, R. N. Davis, D. D'Antonio, Alzheimers Dement 2020
Relationship Between Delirium and Ventilatory Outcomes in the Medical Intensive Care Unit Kerber, K. Zangmeister, J. McNett, M. Crit Care Nurse 2020
Delirium after cardiac arrest: Phenotype, prediction, and outcome Keijzer, H. M. Klop, M. van Putten, M. J. A. M. Hofmeijer, J. Resuscitation 2020

clonazepam
diazepam
haloperidol
lorazepam
midazolam
morphine
oxazepam
propofol
quetiapine
risperidone
temazepam
valproic acid
zolpidem
zopiclone
adult
article
cognition
cohort analysis
comatose patient
consciousness level
consultation
delirium
DSM-5
female
heart arrest
hospital admission
hospital discharge
human
ICD-10
incidence
language disability
long term care
major clinical study
male
middle aged
nursing home
outcome assessment
phenotype
prevalence
priority journal
prospective study
rehabilitation center
telephone interview

Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium Kealy, J. Murray, C. Griffin, E. W. Lopez-Rodriguez, A. B. Healy, D. Tortorelli, L. S. Lowry, J. P. Watne, L. O. Cunningham, C. J Neurosci 2020
Incidental Durotomy is Associated with Increased Risk of Delirium in Patients Aged 65 and Older Kazarian, E. R. Lopez, W. Y. Eizember, S. Blucher, J. A. Culley, D. J. Javedan, H. Kang, J. D. Schoenfeld, A. J. Spine (Phila Pa 1976) 2020
Scheduled intravenous acetaminophen versus nonsteroidal anti-inflammatory drugs (NSAIDs) for better short-term outcomes after esophagectomy for esophageal cancer Kawakami, J. Abe, T. Higaki, E. Hosoi, T. Fukaya, M. Komori, K. Ito, S. Nakatochi, M. Nagino, M. Shimizu, Y. Surg Today 2020

Esophageal surgery
Outcomes
Pain

Experience of morphine therapy for refractory dyspnea as palliative care in advanced heart failure patients Kawaguchi, J. Hamatani, Y. Hirayama, A. Nishimura, K. Nakai, E. Nakamura, E. Miyata, M. Kawano, Y. Takada, Y. Anchi, Y. Funabashi, S. Kuroda, K. Azechi, M. Takahama, H. Anzai, T. Yasuda, S. Kitaoka, H. Izumi, C. J Cardiol 2020

Dyspnea
Heart failure
Morphine
Opioid
Palliative care

Delirium and Developmental Disability: Improving Specificity of a Pediatric Delirium Screen∗ Kaur, S. Silver, G. Samuels, S. Rosen, A. H. Weiss, M. Mauer, E. A. Gerber, L. M. Greenwald, B. M. Traube, C. Pediatric Critical Care Medicine 2020

article
awareness
child
clinical article
cohort analysis
controlled study
delirium
developmental delay
diagnosis
diagnostic test accuracy study
double blind procedure
female
human
interrater reliability
male
nurse
pediatric intensive care unit
predictive value
prospective study
psychiatric diagnosis
psychiatrist
Richmond Agitation Sedation Scale
tertiary health care

Hyperactive Terminal Delirium in Hospice Patients: A Retrospective Cohort Study Kates, J. J Hosp Palliat Nurs 2020
Incidence & Risk Factors of Postoperative Delirium After Spinal Surgery in Older Patients Kang, T. Park, S. Y. Lee, J. H. Lee, S. H. Park, J. H. Kim, S. K. Suh, S. W. Sci Rep 2020
C-reactive protein to albumin ratio as a novel inflammatory biomarker for postoperative delirium in patients undergoing transcatheter aortic valve replacement Kalyoncuoğlu, M. Biter, H. İ Durmuş, G. Baştan, B. Can, M. M. Haseki Tip Bulteni 2020

biological marker
C reactive protein
adult
aged
area under the curve
article
bleeding
cardiopulmonary bypass
cardiovascular mortality
chronic obstructive lung disease
clinical outcome
cohort analysis
computer assisted tomography
Confusion Assessment Method for the Intensive Care Unit Score
controlled study
disease severity
EuroSCORE
female
follow up
heart left ventricle ejection fraction
hospital mortality
hospital readmission
hospitalization
human
inflammation
major clinical study
male
mortality rate
New York Heart Association class
postoperative delirium
predictive value
receiver operating characteristic
retrospective study
Richmond Agitation Sedation Scale
risk factor
scoring system
sensitivity and specificity
transcatheter aortic valve implantation

Emergence delirium in children undergoing dental surgery under general anesthesia Jooma, Z. Perrie, H. Scribante, J. Kleyenstuber, T. Paediatr Anaesth 2020

Paediatric Anesthesia Emergence Delirium score
anxiety
dental
emergence delirium
opioid-free
pediatric anesthesia

Alteration of consciousness as initial presentation in COVID-19: Observation Joob, B. Wiwanitkit, V. Annals of Indian Academy of Neurology 2020

altered state of consciousness
clinical feature
confusion
coronavirus disease 2019
human
letter
Thailand

A systematic review of the impact of delirium on allied health interventions: A surprising lack of data Johnson, D. Maylin, E. Hayes, L. Hair, C. Kraemer, T. Lau, M. Brodtmann, A. Sahathevan, R. Neurology Asia 2020

arthroplasty
cerebrovascular accident
delirium
financial management
health care organization
health impact assessment
incidence
intensive care unit
length of stay
morbidity
mortality
occupational therapy
outcome assessment
physiotherapist
publication
respiratory failure
review
risk factor
sedation
sepsis
sleep quality
speech therapy

Etiology, Clinical Profile and Outcome of Encephalopathy in Elderly John, B. Loomba, V. John, M. J Assoc Physicians India 2020

Aged
Brain Diseases/epidemiology/ etiology
Consciousness Disorders
Female
Humans
Hyponatremia
Middle Aged
Pneumonia
Sepsis

Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial Jin, L. Yao, R. Heng, L. Pang, B. Sun, F. G. Shen, Y. Zhong, J. F. Zhao, P. P. Wu, C. Y. Li, B. P. Medicine (Baltimore) 2020

Aged
Aged, 80 and over
Analgesia, Patient-Controlled/methods/standards
Delirium/drug therapy/ prevention & control
Esophagectomy/methods/ standards
Female
Geriatrics/methods
Humans
Male
Middle Aged
Nerve Block/ methods/standards
Postoperative Complications/drug therapy/prevention & control
Prospective Studies
Ultrasonography/methods/ standards/statistics & numerical data

Cognitive Impairment Level and Elderly Hip Fracture: Implications in Rehabilitation Nursing Jiménez Mola, S. Calvo-Lobo, C. Idoate Gil, J. Seco Calvo, J. Rehabil Nurs 2020
Long-term outcomes of major abdominal surgery and postoperative delirium after multimodal prehabilitation of older patients Janssen, T. L. Steyerberg, E. W. van Hoof-de Lepper, Ccha Seerden, T. C. J. de Lange, D. C. Wijsman, J. H. Ho, G. H. Gobardhan, P. D. van der Laan, L. Surg Today 2020

Functional outcomes
Older patients
Postoperative delirium
Prehabilitation

Young age and severity of motor function are risk factors for psychosis after subthalamic nucleus deep brain stimulation for Parkinson's disease Ito, M. Sasaki, F. Katsuta, N. Sekimoto, S. Jo, T. Nakamura, R. Nakajima, A. Oyama, G. Shimo, Y. Iwamuro, H. Umemura, A. Ohnuma, T. Hattori, N. Psychiatry and Clinical Neurosciences 2020

dopamine receptor stimulating agent
levodopa
age distribution
brain depth stimulation
clinical feature
controlled study
delirium
Delirium Rating Scale
dementia assessment
disease severity
DSM-5
female
Frontal Assessment Battery
hallucination
human
ICD-10
International Parkinson and Movement Disorder Society
letter
major clinical study
male
Mini Mental State Examination
Montreal cognitive assessment
motor performance
neurologic disease assessment
observational study
pareidolia
Parkinson disease
preoperative period
psychosis
retrospective study
risk factor
subthalamic nucleus
Unified Parkinson Disease Rating Scale
university hospital

Impact of frailty and mild cognitive impairment on delirium after cardiac surgery in older patients Itagaki, A. Sakurada, K. Matsuhama, M. Yajima, J. Yamashita, T. Kohzuki, M. J Cardiol 2020

Cardiac surgery
Delirium
Mild cognitive impairment
Physical frailty

Preoperative Risk Assessment for Delirium After Hepatic Resection in the Elderly: a Prospective Multicenter Study Ishihara, A. Tanaka, S. Ueno, M. Iida, H. Kaibori, M. Nomi, T. Hirokawa, F. Ikoma, H. Nakai, T. Eguchi, H. Shinkawa, H. Hayami, S. Maehira, H. Shibata, T. Kubo, S. J Gastrointest Surg 2020

Frailty
Healthcare support
Hypoalbuminemia
Transfer

Emergence Delirium in Elderly Patients as a Potential Predictor of Subsequent Postoperative Delirium: A Descriptive Correlational Study Huang, J. Qi, H. Lv, K. Chen, X. Zhuang, Y. Yang, L. J Perianesth Nurs 2020

correlation
elderly patients
emergence delirium
postoperative delirium

Does Alzheimer's Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes? Hshieh, T. T. Fong, T. G. Schmitt, E. M. Marcantonio, E. R. Xu, G. Gou, Y. R. Travison, T. G. Metzger, E. D. Jones, R. N. Inouye, S. K. J Am Geriatr Soc 2020

Alzheimer’s disease and related dementias
clinical outcomes
delirium
delirium severity
dementia

A Multicomponent Nonpharmacological Intervention to Prevent Delirium for Hospitalized People with Advanced Cancer: A Phase II Cluster Randomized Waitlist Controlled Trial (The PRESERVE Pilot Study) Hosie, A. Phillips, J. Lam, L. Kochovska, S. Noble, B. Brassil, M. Kurrle, S. Cumming, A. Caplan, G. A. Chye, R. Ely, E. W. Lawlor, P. G. Bush, S. H. Davis, J. M. Lovell, M. Parr, C. Williams, S. Hauser, K. McArdle, S. Jacquier, K. Phillipson, C. Kuwahata J Palliat Med 2020

cancer
clinical trial
delirium
inpatients
nonpharmacological
palliative care

The Validity and Reliability of the Japanese Version of the Cornell Assessment of Pediatric Delirium Hoshino, H. Matsuishi, Y. Enomoto, Y. Shimojo, N. Kido, T. Matsuzaki, A. Matsubara, M. Kato, H. Hoshino, T. Traube, C. Silver, G. Kawano, S. Inoue, Y. Pediatr Crit Care Med 2020
The incidence and predictors of postoperative delirium (POD) after brain tumor resection in adults: A cross-sectional survey Hong Chen, M. N. Jiang, H. Chen, B. Fan, L. Shi, W. Jin, Y. Ren, X. Lang, L. Zhu, F. World neurosurgery 2020

adult
aged
anesthesia
article
axilla temperature
brain tumor
cancer surgery
comorbidity
controlled study
demography
electrolyte disturbance
female
hospitalization cost
human
incidence
intensive care unit
length of stay
major clinical study
male
neurosurgery
nurse
operation duration
outcome assessment
postoperative delirium
questionnaire
receiver operating characteristic
retrospective study
Richmond Agitation Sedation Scale
risk factor
surgery
tobacco use

A Systematic Review of Risk Factors for Sleep Disruption in Critically Ill Adults Honarmand, K. Rafay, H. Le, J. Mohan, S. Rochwerg, B. Devlin, J. W. Skrobik, Y. Weinhouse, G. L. Drouot, X. Watson, P. L. McKinley, S. Bosma, K. J. Critical care medicine 2020

adult
anxiety
article
Cinahl
Cochrane Library
comorbidity
controlled clinical trial (topic)
critically ill patient
delirium
Embase
English (language)
female
human
male
Medline
Newcastle-Ottawa scale
noise
pain
risk assessment
risk factor
sleep quality
systematic review
Web of Science

Neurotoxicity in chronic lithium poisoning Hlaing, P. M. Isoardi, K. Z. Page, C. B. Pillans, P. Intern Med J 2020

chronic poisoning
elderly
lithium
neurotoxicity

Postoperative delirium in patients undergoing surgery for bone metastases Hindiskere, S. Kim, H. S. Han, I. Medicine (Baltimore) 2020

Aged
Analgesics, Opioid/administration & dosage/adverse effects
Bone Neoplasms/secondary/ surgery
C-Reactive Protein/analysis
Cognition/drug effects/physiology
Comorbidity
Delirium/epidemiology/ etiology/mortality/psychology
Female
Humans
Incidence
Male
Middle Aged
Neoplasm Metastasis/ pathology
Postoperative Complications/epidemiology
Postoperative Period
Preoperative Period
Retrospective Studies
Risk Factors
Serum Albumin/analysis

Delirium in patients of the Intensive Care Unit of a health institution in Montería, Colombia Herrera Herrera, J. L. Oyola López, E. Llorente Pérez, Y. J. Revista Cientifica de la Sociedad Espanola de Enfermeria Neurologica 2020

adult
APACHE
article
artificial ventilation
clinical feature
Colombia
delirium
epidemiological data
female
health center
hospital admission
human
incidence
intensive care unit
longitudinal study
male
middle aged
quantitative analysis

Total Hip Arthroplasty in Patients With Dementia Hernandez, N. M. Cunningham, D. J. Jiranek, W. A. Bolognesi, M. P. Seyler, T. M. J Arthroplasty 2020

complications
delirium
dementia
revision
total hip arthroplasty
total joint arthroplasty

Neurologic Features in Severe SARS-CoV-2 Infection Helms, J. Kremer, S. Merdji, H. Clere-Jehl, R. Schenck, M. Kummerlen, C. Collange, O. Boulay, C. Fafi-Kremer, S. Ohana, M. Anheim, M. Meziani, F. N Engl J Med 2020

Adult
Aged
Betacoronavirus/genetics/isolation & purification
Brain/diagnostic imaging/ pathology
Brain Diseases/ etiology
Confusion/etiology
Coronavirus Infections/ complications/pathology
Humans
Magnetic Resonance Imaging
Middle Aged
Pandemics
Pneumonia, Viral/ complications/pathology
Respiratory Distress Syndrome, Adult/ complications/virology
Reverse Transcriptase Polymerase Chain Reaction
Stroke/ etiology

Association between delirium prediction scores and days spent with delirium Heesakkers, H. Devlin, J. W. Slooter, A. J. C. van den Boogaard, M. J Crit Care 2020

Critical illness
Delirium
Delirium exposure
Intensive care
Prediction

Association of Hypoactive and Hyperactive Delirium With Cognitive Function After Critical Illness Hayhurst, C. J. Marra, A. Han, J. H. Patel, M. B. Brummel, N. E. Thompson, J. L. Jackson, J. C. Chandrasekhar, R. Ely, E. W. Pandharipande, P. P. Hughes, C. G. Crit Care Med 2020
Mental disorders of geriatric inpatients: symptom characteristics and treatment outcome Haupt, M. Jänner, M. Richert, F. Int Psychogeriatr 2020

clinical symptomatology
comorbidities
geriatric hospital
neuropsychiatric disorders
treatment outcome

Video Glasses Reduce Preoperative Anxiety Compared With Portable Multimedia Player in Children: A Randomized Controlled Trial Hashimoto, Y. Chaki, T. Hirata, N. Tokinaga, Y. Yoshikawa, Y. Yamakage, M. J Perianesth Nurs 2020

anesthesia
anxiety
emergence delirium
pediatrics
video glasses

Assessing Risks of Polypharmacy Involving Medications With Anticholinergic Properties Hanlon, P. Quinn, T. J. Gallacher, K. I. Myint, P. K. Jani, B. D. Nicholl, B. I. Lowrie, R. Soiza, R. L. Neal, S. R. Lee, D. Mair, F. S. Ann Fam Med 2020

anticholinergic burden
cardiovascular events
mortality
multimorbidity
polypharmacy

Melatonin and its analogues for the prevention of postoperative delirium: A systematic review and meta-analysis Han, Y. Wu, J. Qin, Z. Fu, W. Zhao, B. Li, X. Wang, W. Sha, T. Sun, M. Li, J. Zeng, Z. Chen, Z. J Pineal Res 2020

melatonin
meta-analysis
postoperative delirium
ramelteon
systematic review

Proteomic Analysis of Preoperative CSF Reveals Risk Biomarkers of Postoperative Delirium Han, Y. Chen, W. Song, Y. Yuan, Y. Li, Z. Zhou, Y. Liu, T. Han, D. Mi, X. Li, M. Wang, G. Zhong, L. Zhou, J. Guo, X. Front Psychiatry 2020

cerebrospinal fluid
hip fracture
older patients
postoperative delirium
protein profile analysis

Inpatient gastrostomy in Huntington's disease: Nationwide analysis of utilization and outcomes compared to amyotrophic lateral sclerosis Hamedani, A. G. Pauly, M. Thibault, D. P. Gonzalez-Alegre, P. Willis, A. W. Clinical Parkinsonism and Related Disorders 2020

Huntington’s disease

Health services research

Outcome research

Gastrostomy

The Observational Scale of Level of Arousal: A brief tool for assessing and monitoring level of arousal in patients with delirium outside the ICU Hall, R. Stíobhairt, A. Allerhand, M. MacLullich, A. M. J. Tieges, Z. Int J Geriatr Psychiatry 2020

arousal
attention
cognition
delirium
orthopaedic surgery

Development of disturbance of consciousness is associated with increased severity in acute pancreatitis Hágendorn, R. Vincze, Á Izbéki, F. Gajdán, L. Gódi, S. Illés, A. Sarlós, P. Farkas, N. Erőss, B. Lillik, V. Illés, D. Varjú, P. Márta, K. Török, I. Papp, M. Vitális, Z. Bod, B. Hamvas, J. Szepes, Z. Takács, T. Czakó, L. Márton, Z. Szentes Pancreatology 2020

Acute pancreatitis
Alcohol
Delirium
Disturbance of consciousness
Mortality

Prophylactic Physostigmine for Extreme and Refractory Adult Emergence Delirium, Aimed at Increasing Patient Safety and Reducing Health Care Workplace Violence: A Case Report Gutman, D. A. Hassid, M. Jeanes, Z. Redding, A. T. Romeo, D. A and A Practice 2020

adult
article
Barrett esophagus
case report
clinical article
drug safety
drug therapy
emergence agitation
female
human
injury
male
patient safety
remission
surgery
workplace violence
physostigmine

No Brain Is an Island Guay, C. S. Avidan, M. S. Anesth Analg 2020

Brain
Consensus
Delirium
Humans
United States

The role of physical exercise and rehabilitation in delirium Gual, N. García-Salmones, M. Brítez, L. Crespo, N. Udina, C. Pérez, L. M. Inzitari, M. European Geriatric Medicine 2020

brain function
cognition
delirium
exercise
frailty
human
motor dysfunction
neurophysiology
physiotherapy
priority journal
psychosocial rehabilitation
review
risk factor

The incidence of prolonged post-electroconvulsive therapy delirium: A retrospective study Grover, S. Kumar, A. Chakrabarti, S. Avasthi, A. Indian J Psychiatry 2020

Electroconvulsive therapy
India
delirium

Postoperative Delirium in Patients after Hip Fracture Tratment Postoperative Delirium in Patients after Hip Fracture Tratment Grle, M. Markotić, V. Prlić, J. Grle, I. Miljko, M. Psychiatr Danub 2020
Intensive Care Unit Delirium, Clinical Observations, and Patients' Statements: A Case Study Granberg-Axèll, A. Bergbom, I. Dimensions of critical care nursing : DCCN 2020

adult
advanced cancer
article
cancer patient
clinical assessment
clinical research
controlled study
decision making
delirium
female
human
informed consent
life expectancy
major clinical study
male
nurse
observational study
palliative therapy
physician
prospective study
receiver operating characteristic
research ethics

Assessment of the Decision-Making Capacity for Clinical Research Participation in Patients With Advanced Cancer in the Last Weeks of Life Goswami, R. Moore, J. Bruera, E. Hui, D. Journal of Pain and Symptom Management 2020

adult
advanced cancer
article
cancer patient
clinical assessment
clinical research
controlled study
decision making
delirium
female
human
informed consent
life expectancy
major clinical study
male
nurse
observational study
palliative therapy
physician
prospective study
receiver operating characteristic
research ethics

Reducing Delirium in Hospitalized Adults Through a Structured Sleep Promotion Program Gode, A. Kozub, E. Joerger, K. Lynch, C. Roche, M. Kirven, J. J Nurs Care Qual 2020
Preoperative Cognitive Assessment Recommendations for the Older Adult Glover, N. P. Tola, D. H. Norcross, W. Naumuk, L. Tocchi, C. J Perianesth Nurs 2020

Mini-Cog
anesthesia
cognition
older adult
postoperative delirium

Use of Direct In-Person Observation in the Care of Hospitalized Older Adults with Cognitive Impairment: A Systematic Review Gilmore-Bykovskyi, A. L. Fuhr, H. Jin, Y. Benson, C. J Gerontol Nurs 2020
The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study Gibb, K. Seeley, A. Quinn, T. Siddiqi, N. Shenkin, S. Rockwood, K. Davis, D. Age Ageing 2020

delirium
epidemiology
meta-analysis
older people
systematic review

Loss of Independence in Older Patients after Operation for Colorectal Cancer Gearhart, S. L. Do, E. M. Owodunni, O. Gabre-Kidan, A. A. Magnuson, T. J Am Coll Surg 2020
Time to Block: Early Regional Anesthesia Improves Pain Control in Geriatric Hip Fractures Garlich, J. M. Pujari, A. Debbi, E. M. Yalamanchili, D. R. Moak, Z. B. Stephenson, S. K. Stephan, S. R. Polakof, L. S. Johnson, C. R. Noorzad, A. S. Little, M. T. M. Moon, C. N. Black, J. T. Anand, K. K. Lin, C. A. J Bone Joint Surg Am 2020

Brain
Covid-19
Encephalitis
Encephalopathy
Magnetic Resonance Imaging
Sars-cov-2

Encephalopathy in patients with COVID-19: A review Garg, R. K. Paliwal, V. K. Gupta, A. J Med Virol 2020

Brain
Covid-19
Encephalitis
Encephalopathy
Magnetic Resonance Imaging
Sars-cov-2

Prevalence and risk factors of postoperative delirium after spinal surgery: a meta-analysis Gao, H. Ma, H. J. Li, Y. J. Yin, C. Li, Z. J Orthop Surg Res 2020

Delirium
Meta-analysis
Prevalence, Risk factor
Spinal surgery

Prognostic factors for discharge to home and residing at home 12 months after hip fracture: an Anoia hip study Gamboa-Arango, A. Duaso, E. Malafarina, V. Formiga, F. Marimón, P. Sandiumenge, M. Salgado, M. T. Escalante, E. Lumbreras, C. Tarrida, A. Aging Clinical and Experimental Research 2020

aged
anemia
article
Barthel index
blood transfusion
cardiopulmonary insufficiency
Charlson Comorbidity Index
cognition
community dwelling person
controlled study
daily life activity
delirium
dementia assessment
female
functional status
geriatric rehabilitation
geriatrics
Geriatrics Dementia Scale
hip fracture
home care
hospital discharge
human
infection
institutionalization
length of stay
major clinical study
male
marriage
observational study
physical activity
polypharmacy
prognosis
prospective study
very elderly

Safety of the muscarinic receptor-antagonist (R,R)-penehyclidine fumarate in healthy subjects: A phase 1 randomized, double-blind, single-dose escalation study
 Fu, C. Zhang, X. Pei, Q. Guo, C. Yang, X. Yang, S. Huang, J. Yang, G. Int J Clin Pharmacol Ther 2020

Administration, Oral
Adult
Area Under Curve
Dose-Response Relationship, Drug
Double-Blind Method
Female
Fumarates/ administration & dosage/pharmacokinetics
Humans
Infusions, Intravenous
Male
Muscarinic Antagonists/ administration & dosage/pharmacokinetics
Quinuclidines/ administration & dosage/pharmacokinetics
Young Adult

Discriminant Performance of Dysexecutive and Frontal Release Signs for Delirium in Patients With High Dementia Prevalence: Implications for Neural Network Impairment Franco, J. G. Trzepacz, P. T. Velásquez-Tirado, J. D. Ocampo, M. V. Serna, P. A. Giraldo, A. M. López, C. Zuluaga, A. Zaraza-Morales, D. Psychosomatics 2020

abnormal reflex
delirium
dementia
diagnosis
executive function
neural pathways

Survey of psychiatrists and psychiatry residents in Colombia about their preventive and therapeutic practices in delirium Franco, J. G. Oviedo Lugo, G. F. Patarroyo Rodriguez, L. Bernal Miranda, J. Molano, J. C. Rojas Moreno, M. Cardeño, C. Velasquez Tirado, J. D. Revista Colombiana de Psiquiatria 2020

Antipsychotics

Delirium

Health education

Primary prevention

Quality of healthcare

Therapeutics

Adverse Events, Functional Decline, and Access to Allied Health Therapies for Patients With Dementia During Acute Hospitalization Fox, A. MacAndrew, M. Wyles, K. Yelland, C. Beattie, E. J Appl Gerontol 2020

acute care
adverse events
allied health therapy
dementia
functional decline
hospitalization

Outcomes of video-assisted thoracoscopic surgery lobectomy in septuagenarians Fong, L. S. Ko, V. McLaughlin, A. Okiwelu, N. L. Newman, M. A. Passage, J. Sanders, L. H. A. Joshi, P. V. ANZ J Surg 2020

lobectomy
septuagenarian
video-assisted thoracoscopic surgery

Depressive and/or anxiety scoring instruments used as screening tools for predicting postoperative delirium after cardiac surgery: A pilot study Falk, A. Eriksson, M. Stenman, M. Intensive Crit Care Nurs 2020

Cardiac surgery
Delirium
Depression
Intensive care
Screening

Preoperative Depression and Plasma Cortisol Levels as Predictors of Delirium after Cardiac Surgery Eshmawey, M. Arlt, S. Ledschbor-Frahnert, C. Guenther, U. Popp, J. Dementia and Geriatric Cognitive Disorders 2020

hydrocortisone
aged
article
cerebrovascular accident
Charlson Comorbidity Index
cohort analysis
comorbidity
controlled study
depression
disease duration
elective surgery
female
Geriatric Depression Scale
heart surgery
human
hydrocortisone blood level
major clinical study
male
medical history
Mini Mental State Examination
postoperative delirium
preoperative period
priority journal
prospective study
risk factor

Dexmedetomidine versus nalbuphine in prevention of emergence agitation following adenotonsillectomy in pediatrics Elagamy, A. E. Mahran, M. G. Mahmoud, A. Z. Egyptian Journal of Anaesthesia 2020

NCT04058899
dexmedetomidine
nalbuphine
adenotonsillectomy
article
bradycardia
child
controlled study
double blind procedure
emergence agitation
endotracheal intubation
female
heart rate
human
hypotension
legal guardian
major clinical study
male
mean arterial pressure
pediatric anesthesia
pediatric surgery
postoperative nausea and vomiting
postoperative period
preschool child
prospective study
Ramsay Sedation Scale
randomized controlled trial
recovery room
rescue personnel
sex ratio
time to treatment

Predicting Intense Levels of Child Anxiety During Anesthesia Induction at Hospital Arrival Eijlers, R. Staals, L. M. Legerstee, J. S. Berghmans, J. M. Strabbing, E. M. van der Schroeff, M. P. Wijnen, R. M. H. Kind, L. S. Hillegers, M. H. J. Dierckx, B. Utens, Emwj J Clin Psychol Med Settings 2020

Anxiety
Child
Diagnostic techniques and procedures
General anesthesia
Psychometrics

A systematic review and meta-analysis evaluating geriatric consultation on older trauma patients Eagles, D. Godwin, B. Cheng, W. Moors, J. Figueira, S. Khoury, L. Fournier, K. Lampron, J. J Trauma Acute Care Surg 2020
Association between incident delirium and 28- and 90-day mortality in critically ill adults: a secondary analysis Duprey, M. S. van den Boogaard, M. van der Hoeven, J. G. Pickkers, P. Briesacher, B. A. Saczynski, J. S. Griffith, J. L. Devlin, J. W. Crit Care 2020

Coma
Delirium
Intensive care
Mortality
Risk factors

Delirium in Meningitis and Encephalitis: Emergence and Prediction in a 6-Year Cohort Dittrich, T. Marsch, S. Rüegg, S. De Marchis, G. M. Tschudin-Sutter, S. Sutter, R. J Intensive Care Med 2020

delirium
encephalitis
meningitis
meningoencephalitis
neurocritical care

Neuropsychiatric aspects of COVID-19 pandemic: A selective review Dinakaran, D. Manjunatha, N. Naveen Kumar, C. Suresh, B. M. Asian J Psychiatr 2020

Covid-19
Delirium
Neuroinvasion
Neurology
Neuropsychiatry

Psychometric properties of the intensive care delirium screening checklist when used by bedside nurses in clinical practice: a prospective descriptive study Detroyer, E. Timmermans, A. Segers, D. Meyfroidt, G. Dubois, J. Van Assche, A. Joosten, E. Milisen, K. BMC Nurs 2020

Delirium
Intensive care delirium screening checklist
Psychometrics
Sensitivity and specificity
User-friendliness
Validation studies

Delirium in a tertiary PICU: Risk factors and outcomes* Dervan, L. A. Di Gennaro, J. L. Farris, R. W. D. Watson, R. S. Pediatric Critical Care Medicine 2020

age
article
artificial ventilation
child
cognitive defect
cohort analysis
controlled study
critical illness
dose response
electronic medical record
female
human
length of stay
linear regression analysis
major clinical study
male
mortality
pediatric intensive care unit
retrospective study
risk factor
tertiary health care
benzodiazepine derivative
hypnotic sedative agent

Factors associated with ABCDE bundle adherence in critically ill adults requiring mechanical ventilation: An observational design DeMellow, J. M. Kim, T. Y. Romano, P. S. Drake, C. Balas, M. C. Intensive Crit Care Nurs 2020

ABCDE bundle
Adherence
Intensive care
Mechanical ventilation
Performance monitoring
Sedation

Clinical practice in the management of postoperative delirium by Chinese anesthesiologists: a cross-sectional survey designed by the European Society of Anaesthesiology Delp, S. Mei, W. Spies, C. D. Neuner, B. Aldecoa, C. Bettelli, G. Bilotta, F. Sanders, R. D. Kramer, S. Weiss, B. J Int Med Res 2020

China
Postoperative delirium
anesthesiologists
practice
screening
survey

Development of a Palliative Care Toolkit for the COVID-19 Pandemic deLima Thomas, J. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. J Pain Symptom Manage 2020

Covid-19
Palliative care
clinical service delivery
innovation
pandemic
toolkit

Adherence to recommended practices for perioperative anesthesia care for older adults among US anesthesiologists: Results from the ASA Committee on Geriatric Anesthesia-Perioperative Brain Health Initiative ASA member survey Deiner, S. Fleisher, L. A. Leung, J. M. Peden, C. Miller, T. Neuman, M. D. Neuman, M. D. Akhtar, S. Arora, S. Bentov, I. Bhandary, S. Brzezinski, M. Burstrom, R. E. Deiner, S. Evans, K. Leung, J. Lewis, M. C. Mahboobi, S. McSwain, J. Rooke, A. Whittington Perioperative Medicine 2020

aged
anesthesiologist
cognition
cognitive defect
consultation
dementia
frailty
geriatric anesthesia
geriatric assessment
geriatric care
health care delivery
health survey
human
patient care
perioperative anesthesia care
perioperative period
postoperative delirium
practice guideline
priority journal
protocol compliance
questionnaire
review

Evaluation of an Educational Intervention Utilizing Nurse "Champions" and Nurses' Documentation of Intensive Care Unit Delirium DeForge, C. E. Yip, N. H. Dzierba, A. L. Ryan, P. G. Larson, E. L. Dimens Crit Care Nurs 2020

Cognitive interventions
Delirium
Delirium prevention
ICU delirium
Ocupational therapist

Effect of early cognitive interventions on delirium in critically ill patients: a systematic review Deemer, K. Zjadewicz, K. Fiest, K. Oviatt, S. Parsons, M. Myhre, B. Posadas-Calleja, J. Can J Anaesth 2020

Cognitive interventions
Delirium
Delirium prevention
ICU delirium
Ocupational therapist

C-Reactive Protein and Procalcitonin Levels May Not Predict Delirium in Critically Ill Children Dechnik, A. Mauer, E. A. Gerber, L. M. Traube, C. Pediatr Crit Care Med 2020
‘Nonagenarians’ with a hip fracture: is a different orthogeriatric treatment strategy necessary? de Groot, R. Nijmeijer, W. S. Folbert, E. C. Vollenbroek-Hutten, M. M. R. Hegeman, J. H. Archives of Osteoporosis 2020

cannulated screw
dynamic hip screw
femur nail
hip prosthesis
aged
aging
Almelo Hip Fracture Score
anemia
article
avascular necrosis
cerebrovascular accident
cohort analysis
comorbidity
controlled study
daily life activity
female
femur head necrosis
heart arrhythmia
heart failure
heart infarction
hematoma
hemoglobin blood level
hip fracture
hip hemiarthroplasty
hospital mortality
hospital readmission
human
major clinical study
male
mortality rate
nursing home
osteosynthesis
pathologic fracture
patient mobility
periprosthetic fracture
pneumonia
postoperative complication
postoperative delirium
priority journal
prospective study
prosthesis complication
prosthesis dislocation
reoperation
risk factor
scoring system
urinary tract infection
very elderly
wound dehiscence
wound infection

A quality improvement project for delirium prevention and management over the Greater Manchester Critical Care Network Davis, J. Berry, K. McIntyre, R. Conway, D. Thomas, A. Hanison, J. Journal of the Intensive Care Society 2020

Delirium

Critical Care

Critical Illness

Delirium Care Bundles

Patient Care Bundles

Relationship Between Pain, Opioid Treatment, and Delirium in Older Emergency Department Patients Daoust, R. Paquet, J. Boucher, V. Pelletier, M. Gouin, É Émond, M. Acad Emerg Med 2020
Impact of Early Reinitiation of Neuropsychiatric Medications on Agitation and Delirium in the Intensive Care Unit: A Retrospective Study Cucci, M. D. Cunningham, B. S. Patel, J. S. Shimer, A. T. Mofleh, D. I. Mullen, C. L. Ann Pharmacother 2020

agitation
antipsychotics
delirium
neuropsychiatric
restraints
withdrawal

Valproic Acid for the Management of Agitation and Delirium in the Intensive Care Setting: A Retrospective Analysis Crowley, K. E. Urben, L. Hacobian, G. Geiger, K. L. Clin Ther 2020

agitation
delirium
divalproex
intensive care unit
valproate
valproic acid

Multimodal Pain Management and Postoperative Outcomes in Lumbar Spine Fusion Surgery: A Population-based Cohort Study Cozowicz, C. Bekeris, J. Poeran, J. Zubizarreta, N. Schwenk, E. Girardi, F. Memtsoudis, S. G. Spine (Phila Pa 1976) 2020
Systematic symptom and problem assessment at admission to the palliative care ward - Perspectives and prognostic impacts Coym, A. Ullrich, A. Hackspiel, L. K. Ahrenholz, M. Bokemeyer, C. Oechsle, K. BMC Palliative Care 2020

adult
caregiver
checklist
clinical evaluation
confusion
controlled study
daily life activity
documentation
dyspnea
factor analysis
fatigue
female
gastrointestinal symptom
home care
hospice
hospital patient
human
loss of appetite
major clinical study
male
pain
palliative therapy
patient-reported outcome
physician
prognosis
reliability
review
self evaluation
symptom assessment
thermometer
weakness

What are we asking for when requesting "Specialling" for the confused hospitalised older person? A concept analysis Coyle, M. A. Wilson, V. Lapkin, S. Traynor, V. Int J Older People Nurs 2020

acute care
aged care
cognitive impairment
concept analysis
delirium
dementia
hospital setting
older people
specialling

Delirium accompanies kidney dysfunction in hospitalized elderly patients Coppolino, G. Castagna, A. Provenzano, M. Ruberto, C. Leonardi, G. Greco, L. Battaglia, G. G. Cerra, R. P. Andreucci, M. Bolignano, D. Ruotolo, G. Journal of Gerontology and Geriatrics 2020

low density lipoprotein cholesterol
potassium
uric acid
aged
aged hospital patient
article
Assessment Test for Delirium and Cognitive Impairment
chronic kidney failure
cognition assessment
cognitive defect
cohort analysis
delirium
disease association
disease severity
estimated glomerular filtration rate
female
gender
human
kidney dysfunction
major clinical study
male
prevalence
risk factor
smoking
very elderly

An observational study of older patient specialling in acute hospital settings Cook, J. Palesy, D. Lapkin, S. Chenoweth, L. Int J Older People Nurs 2020

acute hospital
delirium
general ward
nursing
observation
older patient
specialling

Fundamental care for people with cognitive impairment in the hospital setting: A study combining positive organisational scholarship and video-reflexive ethnography Collier, A. De Bellis, A. Hosie, A. Dadich, A. Symonds, T. Prendergast, J. Rodrigues, J. Bevan, A. J Clin Nurs 2020

Gait speed
Geriatrics
Grip strength
Multidimensional frailty score
Prognosis
Surgery

Comparison of multidimensional frailty score, grip strength, and gait speed in older surgical patients Choi, J. Y. Kim, K. I. Choi, Y. Ahn, S. H. Kang, E. Oh, H. K. Kim, D. W. Kim, E. K. Yoon, Y. S. Kang, S. B. Kim, H. H. Han, H. S. Kim, C. H. J Cachexia Sarcopenia Muscle 2020

Gait speed
Geriatrics
Grip strength
Multidimensional frailty score
Prognosis
Surgery

Sleep Disturbance Strongly Related to the Development of Postoperative Delirium in Proximal Femoral Fracture Patients Aged 60 or Older Cho, M. R. Song, S. K. Ryu, C. H. Hip Pelvis 2020

Delirium
Hip fractures
Sleep

Variation in the Management of Pain, Agitation, and Delirium in Intensive Care Units in British Columbia Chiu, J. A. Shergill, M. Dhingra, V. Ronco, J. J. LeBlanc, A. Pamplin, C. McKeown, S. Dodek, P. M. Am J Crit Care 2020
Is hospitalisation a risk factor for cognitive decline in the elderly? Chinnappa-Quinn, L. Bennett, M. Makkar, S. R. Kochan, N. A. Crawford, J. D. Sachdev, P. S. Curr Opin Psychiatry 2020
Clinical studies on the relationship of the short duration of use of midazolam with the occurrence of delirium in icu patients with mechanical ventilation Chen, Z. F. Farmacia 2020

midazolam
propofol
sufentanil
adult
anesthetic recovery
article
artificial ventilation
bradycardia
continuous infusion
controlled study
delirium
double blind procedure
drug use
female
human
hypotension
incidence
intensive care unit
major clinical study
male
mental health
nausea
prospective study
randomized controlled trial
sedation
Sedation Agitation Scale
treatment duration

Preoperative Circulating MiR-210, a Risk Factor for Postoperative Delirium among Elderly Patients with Gastric Cancer Undergoing Curative Resection Chen, Y. Zheng, J. Chen, J. Curr Pharm Des 2020

Gastric cancer
biomarker
microRNAs
postoperative delirium

The Incidence and Predictors of Postoperative Delirium After Brain Tumor Resection in Adults: A Cross-Sectional Survey Chen, H. Jiang, H. Chen, B. Fan, L. Shi, W. Jin, Y. Ren, X. Lang, L. Zhu, F. World Neurosurg 2020

Delirium
Neurosurgery
Nursing
Postoperative delirium
Risk factors

Baclofen has a risk of encephalopathy in older adults receiving dialysis Chauvin, K. J. Blake, P. G. Garg, A. X. Weir, M. A. Bathini, L. Dixon, S. N. McArthur, E. Sontrop, J. M. Moist, L. Kim, R. B. Muanda, F. T. Kidney Int 2020

baclofen
dialysis
end stage kidney disease
toxicity

Delirium Among Hospitalized Older Adults in Thailand: An Integrative Review Chang, H. C. R. Neal, K. Traynor, V. Ho, M. H. Kankom, W. J Gerontol Nurs 2020