What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Peripheral interleukin-6-associated microglial QUIN elevation in basolateral amygdala contributed to cognitive dysfunction in a mouse model of postoperative delirium
- Authors
- Mu, J. L. Liu, X. D. Dong, Y. H. Fang, Y. Y. Qiu, S. D. Zhang, F. Liu, K. X.
- Year
- 2022
- Journal
- Front Med (Lausanne)
- Abstract
BACKGROUND: Developing effective approaches for postoperative delirium has been hampered due to the lack of a pathophysiologically similar animal model to offer insights into the pathogenesis. The study, therefore, aimed to develop a delirium-like mouse model and explore the underlying mechanism. METHODS: The three cycles of 10-min clamp following 5-min reopening of the superior mesenteric artery (SMA) were performed in adult male C57BL/6 mice to induce a delirium-like phenotype. Composite Z score calculated based on the results of Open Field, Y Maze and Buried Food Tests was employed to assess the delirium phenotype in mice. Microglia activities were monitored by immunofluorescence staining and comprehensive morphological analysis. Systemic administration of minocycline (MINO), IL-6 antibody or IL-6 neutralizing antibody, was applied to manipulate microglia. The expressions of Indoleamine 2,3-dioxygenase-1 (IDO-1) and quinolinic acid (QUIN) were examined by RT-PCR and High-Performance Liquid Chromatography/Mass Spectrometry, respectively. Cytokines were measured using fluorescence activated cell sorting method. RESULTS: The repeated ischemia/reperfusion (I/R) surgery caused significant anxiety (P < 0.05) and cognition decline in working memory and orientation (P < 0.05) in mice at postoperative 24 h. The composite Z score, indicating an overall disturbance of brain function, fluctuated over 24 h after I/R surgery (P < 0.001). Immunofluorescent staining showed that the percentage of microglia in the basolateral amygdala (BLA) (P < 0.05) was reactivated after I/R surgery and was negatively correlated with dwell time at Y maze (R = -0.759, P = 0.035). Inhibiting microglia activities by MINO reduced QUIN productions (P < 0.01) that improved cognitive deficits (P < 0.05). The peripheral IL-6 might cause IL-6 elevation in the BLA. Systemic administration of IL-6 antibodies suppressed I/R-induced IL-6 elevations (P < 0.05), microglial reactivations (P < 0.05), IDO-1 expressions (P < 0.01), and neuroactive metabolite QUIN productions (P < 0.05) in the BLA, resulting in a recovery of cognitive deficits (P < 0.05). Injection of IL-6 exerted opposite effects. CONCLUSION: The repeated intestinal I/R surgery-induced mouse model is a simple and reproducible one of postoperative delirium. Peripheral IL-6-associated microglial QUIN elevations in the BLA contributed to cognitive dysfunction in the model of postoperative delirium.
- PMID
- Keywords
Bla
Il-6
Quin
delirium
microglia
repeated intestinal I/R
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis | Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. | J Clin Anesth | 2020 |
Cardiac complications |
| Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study | Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. | J Geriatr Oncol | 2020 |
Aged 80 and over |
| Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study | Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. | Anesthesia and Analgesia | 2020 |
adult |
| Development of a clinical score, PANDA, to predict delirium in stroke care unit | Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. | J Neurol Sci | 2020 |
Area under curve |
| Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study | Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. | Clinical Spine Surgery | 2020 |
adult |
| Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients | Naghibi, T. Shafigh, N. Mazloomzadeh, S. | Journal of Research in Medical Sciences | 2020 |
IRCT2015095536N5 |
| Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery | Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. | Crit Care | 2020 |
Anesthesia |
| Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? | Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. | British Journal of Clinical Pharmacology | 2020 |
quetiapine |
| Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() | Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. | Intern Med J | 2020 |
delirium |
| Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients | Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. | BMC Psychiatry | 2020 |
3d-cam |
| Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial | Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. | J Res Pharm Pract | 2020 |
Delirium |
| How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study | Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. | Supportive Care in Cancer | 2020 | |
| Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia | Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. | Journal of the American Medical Directors Association | 2020 |
intravenous catheter |
| Infection in older adults: a qualitative study of patient experience | Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. | Br J Gen Pract | 2020 |
aged |
| Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study | Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. | Eur J Clin Pharmacol | 2020 |
Aripiprazole |
| Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria | Moebs, I. Abeln, E. Siefert, A. Barak, Y. | Neurology and Therapy | 2020 |
adult |
| An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study | Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. | Osteoporos Int | 2020 |
Aged care |
| Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study | Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. | BMC Nurs | 2020 |
Co-design |
| Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis | Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. | Ann Palliat Med | 2020 |
Dexmedetomidine |
| Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium | Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. | Pediatr Crit Care Med | 2020 | |
| Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients | Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. | World J Psychiatry | 2020 |
Assessment |
| A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients | Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. | Aging & mental health | 2020 |
adult |
| Family intervention improves outcomes for patients with delirium: Systematic review and meta-analysis | McKenzie, J. Joy, A. | Australas J Ageing | 2020 |
caregivers |
| Effectiveness and Safety of Intrathecal Ziconotide: Final Results of the Patient Registry of Intrathecal Ziconotide Management (PRIZM) | McDowell, G. C. Saulino, M. F. Wallace, M. Grigsby, E. J. Rauck, R. L. Kim, P. Vanhove, G. F. Ryan, R. Huang, I. Z. Deer, T. | Pain medicine (Malden, Mass.) | 2020 |
adult |
| Management Effort for Delirium and Insomnia in Patients with Acute Ischemic Stroke (MEDIAS) Study | Matsuzono, K. Mashiko, T. Ozawa, T. Miura, K. Suzuki, M. Furuya, K. Ozawa, M. Anan, Y. Shimazaki, H. Koide, R. Tanaka, R. Fujimoto, S. | Psychiatry Clin Neurosci | 2020 | |
| High Prevalence of Oropharyngeal Dysphagia in Acutely Hospitalized Patients Aged 80 Years and Older | Mateos-Nozal, J. Montero-Errasquín, B. Sánchez García, E. Romero Rodríguez, E. Cruz-Jentoft, A. J. | J Am Med Dir Assoc | 2020 |
Dysphagia |
| Dexmedetomidine in medical cardiac intensive care units. Data from a multicenter prospective registry | Mateos Gaitan, R. Vicent, L. Rodriguez-Queralto, O. Lopez-de-Sa, E. Elorriaga, A. Pastor, G. Bañeras, J. Lorenzo, B. García-Rubira, J. C. Corbi, M. Ariza, A. Martínez-Sellés, M. | Int J Cardiol | 2020 |
Adverse effects |
| Myocardial Function in Patients With Radiation-Associated Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Layer-Specific Strain Analysis Study | Martinez, C. Cicenia, M. Sprynger, M. Postolache, A. Ilardi, F. Dulgheru, R. Radermecker, M. Esposito, G. Marechal, P. Marechal, V. Donis, N. Tridetti, J. Nguyen Trung, M. L. Sugimoto, T. Tsugu, T. Go, Y. Y. Coisne, A. Montaigne, D. Fattouch, K. Nchimi, A | JACC: Cardiovascular Imaging | 2020 |
CoreValve self-expandable biologic prosthesis |
| Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review | Manfredonia, F. Saturno, E. Lawley, A. Gasverde, S. Cavanna, A. E. | J Neurol Sci | 2020 |
Acute confusional state |
| Downstream consequences of abnormal cognitive screening in older adults seen pretreatment in a geriatric oncology clinic | Malik, U. Alam, Z. Loucks, A. Jin, R. Yokom, D. Watt, S. Berger, A. Romanovsky, L. Puts, M. Alibhai, S. M. H. | J Geriatr Oncol | 2020 |
Cognitive impairment |
| A Study of the Psychometric Properties of the "Stanford Proxy Test for Delirium" (S-PTD): A New Screening Tool for the Detection of Delirium | Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. | Psychosomatics | 2020 |
S-ptd |
| Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) | Mailhot, T. Darling, C. Ela, J. Malyuta, Y. Inouye, S. K. Saczynski, J. | J Am Geriatr Soc | 2020 |
Fam-cam |
| Frailty Is Associated With Postoperative Delirium But Not With Postoperative Cognitive Decline in Older Noncardiac Surgery Patients | Mahanna-Gabrielli, E. Zhang, K. Sieber, F. E. Lin, H. M. Liu, X. Sewell, M. Deiner, S. G. Boockvar, K. S. | Anesth Analg | 2020 |
Aged |
| 2019-NCoV: What every neurologist should know? | Mahajan, N. Singla, M. Singh, B. Sajja, V. Bansal, P. Paul, B. Goel, P. Midha, R. Bansal, R. Singh, G. | Annals of Indian Academy of Neurology | 2020 |
alanine aminotransferase |
| Age, Comorbidities and Fear of Fall: mortality predictors associated with fall-related fractures | Magdalini, V. Petros, I. Constantinos, T. Garyfalia, S. P. Emmanouil, P. Christos, K. George, K. Kalliopi, A. George, S. Symeon, H. P. | Maedica (Buchar) | 2020 | |
| Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness | Maas, M. B. Lizza, B. D. Kim, M. Abbott, S. M. Gendy, M. Reid, K. J. Zee, P. C. | Crit Care Med | 2020 | |
| Incidence and risk factors of delirium in icu patients | Ma, W. Zheng, J. Xu, S. Huo, Z. | International Journal of Clinical and Experimental Medicine | 2020 |
stomach tube |
| Age, preoperative higher serum cortisol levels, and lower serum acetylcholine levels predict delirium after percutaneous coronary intervention in acute coronary syndrome patients accompanied with renal dysfunction | Ma, J. Fan, M. Wang, Z. | Indian Journal of Psychiatry | 2020 |
IE33 |
| Non-Pharmacologic Multicomponent Interventions Preventing Delirium in Hospitalized People | Ludolph, P. Stoffers-Winterling, J. Kunzler, A. M. Rösch, R. Geschke, K. Vahl, C. F. Lieb, K. | J Am Geriatr Soc | 2020 |
delirium |
| Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women | Lu, G. W. Chou, Y. E. Jin, W. L. Su, X. B. | J Int Med Res | 2020 |
Translocator protein |
| Characteristics, Symptom Management, and Outcomes of 101 Patients With COVID-19 Referred for Hospital Palliative Care | Lovell, N. Maddocks, M. Etkind, S. N. Taylor, K. Carey, I. Vora, V. Marsh, L. Higginson, I. J. Prentice, W. Edmonds, P. Sleeman, K. E. | J Pain Symptom Manage | 2020 |
Covid-19 |
| Characterisation of ICU sleep by a commercially available activity tracker and its agreement with patient-perceived sleep quality | Louzon, P. Andrews, J. Torres, X. Pyles, E. Ali, M. Du, Y. Devlin, J. | BMJ Open Respir Res | 2020 |
equipment evaluations |
| Surgical treatment of hip fracture in centenarians: Complications and independent risk factors of death | López, Torres, II Sanz-Ruiz, P. Montero-Fernández, N. Chana, F. Serra-Rexach, J. A. Benjumea-Carrasco, A. Vaquero-Martín, J. | Injury | 2020 |
Centenarians |
| Long-term survival of femoral neck fracture patients aged over ninety years: Arthroplasty compared with nonoperative treatment | Liu, Y. Zhang, C. W. Zhao, X. D. | BMC Musculoskeletal Disorders | 2020 |
albumin |
| Subjective memory complaints predict poorer functional recovery during the first year following hip-fracture surgery among elderly adults | Liu, H. Y. Wang, H. P. Chen, C. Y. Wu, C. C. Hua, M. S. Lin, Y. E. Lin, Y. C. Shyu, Y. L. | Int J Geriatr Psychiatry | 2020 |
hip fracture |
| Delirium Severity Trajectories and Outcomes in ICU Patients: Defining a Dynamic Symptom Phenotype | Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. | Ann Am Thorac Soc | 2020 | |
| Early mobilisation of ventilated patients in the intensive care unit: A survey of critical care clinicians in an Australian tertiary hospital | Lin, F. Phelan, S. Chaboyer, W. Mitchell, M. | Aust Crit Care | 2020 |
Attitudes |
| Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study | Likhvantsev, V. V. Landoni, G. Grebenchikov, O. A. Ovezov, A. M. Skripkin, Y. V. Lembo, R. Gaevskiy, D. I. Tereshina, A. A. Yavorovskiy, A. G. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
| Derivation and Validation of a Risk Stratification System for Predicting Postoperative Cognitive Impairment | Liao, Y. Su, X. Ouyang, W. Li, L. Chen, S. Chou, J. Le, Y. | J Invest Surg | 2020 |
Postoperative cognitive dysfunction |
| Effects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis | Li, Y. Zhang, B. | Minerva Anestesiol | 2020 | |
| Prevalence, outcome and prognostic factors of neuropsychiatric systemic lupus erythematosus: A real world single center study | Li, X. Xiang, X. Sun, J. Liu, S. Liu, Y. Feng, L. Li, C. Li, Z. | Mod Rheumatol | 2020 |
Neuropsychiatric systemic lupus erythematosus |
| Postoperative Delirium Following Joint Replacement in Patients With Dementia in New South Wales, Australia: A State-Wide Retrospective Cohort Study | Li, X. Du, W. Parkinson, A. Glasgow, N. | Research in gerontological nursing | 2020 |
adult |
| Effect of dexmedetomidine on prevention of postoperative nausea and vomiting in pediatric strabismus surgery: a randomized controlled study | Li, S. Liu, T. Xia, J. Jia, J. Li, W. | BMC Ophthalmol | 2020 |
Dexmedetomidine |
| Toxicity and survival outcomes of autologous stem cell transplant in multiple myeloma patients with renal insufficiency: an institutional comparison between two eras | Li, A. Y. Atenafu, E. G. Bernard, R. S. Masih-Khan, E. Reece, D. Franke, N. Tiedemann, R. Prica, A. Trudel, S. Kukreti, V. Chen, C. I. | Bone Marrow Transplant | 2020 | |
| Risk Prediction for Adverse Outcomes for Frail Older Persons with Complex Healthcare and Social Care Needs Admitted to a Community Virtual Ward Model | Lewis, C. O'Caoimh, R. Patton, D. O'Connor, T. Moore, Z. Nugent, L. E. | Clin Interv Aging | 2020 |
case management |
| The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review | Lewandowska, K. Małkiewicz, M. A. Siemiński, M. Cubała, W. J. Winklewski, P. J. Mędrzycka-Dąbrowska, W. A. | Sleep Med | 2020 |
Delirium |
| Neurological manifestations associated with COVID-19: a review and a call for action | Leonardi, M. Padovani, A. McArthur, J. C. | Journal of Neurology | 2020 |
acroparesthesia |
| "You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting | Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. | J Clin Nurs | 2020 |
adult |
| The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial | Lee-Archer, P. F. von Ungern-Sternberg, B. S. Reade, M. Betts, M. Haenke, D. Keys, A. Rance, T. Gibbons, K. Long, D. | Anaesthesia | 2020 |
behaviour changes |
| Developing delirium best practice: a systematic review of education interventions for healthcare professionals working in inpatient settings | Lee, S. Y. Fisher, J. Wand, A. P. F. Milisen, K. Detroyer, E. Sockalingam, S. Agar, M. Hosie, A. Teodorczuk, A. | European Geriatric Medicine | 2020 |
behavior change |
| Outcomes of the Extreme Elderly Undergoing Anaesthesia and Surgery amongst Southeast Asians | Lee, S. J. Ng, O. Thong, S. Y. | Anesthesiology Research and Practice | 2020 |
dynamic hip screw |
| Predictors of New-Onset Physical Restraint Use in Critically Ill Adults | Lawson, T. N. Tan, A. Thrane, S. E. Happ, M. B. Mion, L. C. Tate, J. Balas, M. C. | Am J Crit Care | 2020 | |
| Decision-making for older patients undergoing emergency laparotomy: defining patient and clinician values and priorities | Law, J. Welch, C. Javanmard-Emamghissi, H. Clark, M. Bisset, C. N. O'Neil, P. Moug, S. J. | Colorectal Dis | 2020 |
Emergency laparotomy |
| Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study | Larsen, L. K. Møller, K. Petersen, M. Egerod, I. | Intensive & critical care nursing | 2020 |
adult |
| Comparison of Hydromorphone versus Fentanyl-based Sedation in Extracorporeal Membrane Oxygenation: A Propensity-Matched Analysis | Landolf, K. M. Rivosecchi, R. M. Goméz, H. Sciortino, C. M. Murray, H. N. Padmanabhan, R. R. Sanchez, P. G. Harano, T. Sappington, P. L. | Pharmacotherapy | 2020 |
acute respiratory distress syndrome |
| Collaborative Delirium Prevention in the Age of COVID-19 | LaHue, S. C. James, T. C. Newman, J. C. Esmaili, A. M. Ormseth, C. H. Ely, E. W. | J Am Geriatr Soc | 2020 |
Aged |
| Intra-operative hyperoxia and the risk of delirium in elderly patients after cardiac surgery | Kupiec, A. Adamik, B. Forkasiewicz-Gardynik, K. Goździk, W. | Aging (Albany NY) | 2020 |
cardiac surgery |
| Clinical profile and predictor of adverse outcome in children with acute encephalitis syndrome: A cross-sectional study | Kuntal, M. Swarnkar, K. | Journal of Krishna Institute of Medical Sciences University | 2020 |
immunoglobulin M |
| Intraoperative Optimization of Both Depth of Anesthesia and Cerebral Oxygenation in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery-A Randomized Controlled Pilot Trial | Kunst, G. Gauge, N. Salaunkey, K. Spazzapan, M. Amoako, D. Ferreira, N. Green, D. W. Ballard, C. | J Cardiothorac Vasc Anesth | 2020 |
cardiac anesthesia |
| Establishment of an enhanced recovery after surgery protocol in minimally invasive heart valve surgery | Kubitz, J. C. Schulte-Uentrop, L. Zoellner, C. Lemke, M. Messner-Schmitt, A. Kalbacher, D. Sill, B. Reichenspurner, H. Koell, B. Girdauskas, E. | PLoS One | 2020 | |
| Preoperative cognitive impairment associated with oversedation during recovery from anesthesia | Kruthiventi, S. C. Laporta, M. L. Deljou, A. Knopman, D. S. Petersen, R. C. Schroeder, D. R. Sprung, J. Weingarten, T. N. | J Anesth | 2020 |
Anesthesia |
| Non-contact monitoring of agitation and use of a sheltering device in patients with dementia in emergency departments: a feasibility study | Kroll, L. Böhning, N. Müßigbrodt, H. Stahl, M. Halkin, P. Liehr, B. Grunow, C. Kujumdshieva-Böhning, B. Freise, C. Hopfenmüller, W. Friesdorf, W. Jockers-Scherübl, M. Somasundaram, R. | BMC Psychiatry | 2020 |
Dementia, agitation |
| COVID-19: ICU delirium management during SARS-CoV-2 pandemic | Kotfis, K. Williams Roberson, S. Wilson, J. E. Dabrowski, W. Pun, B. T. Ely, E. W. | Crit Care | 2020 |
Betacoronavirus |
| COVID-19: What do we need to know about ICU delirium during the SARS-CoV-2 pandemic? | Kotfis, K. Williams Roberson, S. Wilson, J. Pun, B. Ely, E. W. Jeżowska, I. Jezierska, M. Dabrowski, W. | Anaesthesiol Intensive Ther | 2020 |
Pics |
| The impact of acute kidney injury in the perioperative period on the incidence of postoperative delirium in patients undergoing coronary artery bypass grafting—observational cohort study | Kotfis, K. Ślozowska, J. Listewnik, M. Szylińska, A. Rotter, I. | International Journal of Environmental Research and Public Health | 2020 |
creatinine |
| Association between Preoperative Obstructive Sleep Apnea and Preoperative Positive Airway Pressure with Postoperative Intensive Care Unit Delirium | King, C. R. Fritz, B. A. Escallier, K. Ju, Y. E. S. Lin, N. McKinnon, S. Avidan, M. S. Palanca, B. J. | JAMA Network Open | 2020 |
adult |
| Risk factors and outcomes of sepsis-associated delirium in intensive care unit patients: A secondary data analysis | Kim, Y. Jin, Y. Jin, T. Lee, S. M. | Intensive Crit Care Nurs | 2020 |
Delirium |
| Factors affecting the post-anesthetic recovery score and length of stay in the recovery room in elderly patients with hypertension | Kim, S. Kwon, M. | Medico-Legal Update | 2020 |
aged |
| Comparative efficacy and acceptability of pharmacological interventions for the treatment and prevention of delirium: A systematic review and network meta-analysis | Kim, M. S. Rhim, H. C. Park, A. Kim, H. Han, K. M. Patkar, A. A. Pae, C. U. Han, C. | J Psychiatr Res | 2020 |
Antipsychotics |
| Pre-operative hemoglobin level and use of sedative-hypnotics are independent risk factors for post-operative delirium following total knee arthroplasty | Kijima, E. Kayama, T. Saito, M. Kurosaka, D. Ikeda, R. Hayashi, H. Kubota, D. Hyakutake, T. Marumo, K. | BMC Musculoskelet Disord | 2020 |
Anemia |
| Decreasing Delirium Through Music: A Randomized Pilot Trial | Khan, S. H. Xu, C. Purpura, R. Durrani, S. Lindroth, H. Wang, S. Gao, S. Heiderscheit, A. Chlan, L. Boustani, M. Khan, B. A. | Am J Crit Care | 2020 | |
| Time trends of delirium rates in the intensive care unit | Khan, S. H. Lindroth, H. Hendrie, K. Wang, S. Imran, S. Perkins, A. J. Gao, S. Vahidy, F. S. Boustani, M. Khan, B. A. | Heart Lung | 2020 |
Delirium |
| Neurological complications in recipients after living donor liver transplantation | Khalil, M. Elbanhawy, I. Elsherbiny, A. Amer, H. Ahmed, S. | Neurology India | 2020 |
ammonia |
| International drive to illuminate delirium: A developing public health blueprint for action | Khachaturian, A. S. Hayden, K. M. Devlin, J. W. Fleisher, L. A. Lock, S. L. Cunningham, C. Oh, E. S. Fong, T. G. Fick, D. M. Marcantonio, E. R. Iyengar, V. Rockwood, K. Kuchel, G. A. Eckenhoff, R. G. MacLullich, A. M. J. Jones, R. N. Davis, D. D'Antonio, | Alzheimers Dement | 2020 | |
| Relationship Between Delirium and Ventilatory Outcomes in the Medical Intensive Care Unit | Kerber, K. Zangmeister, J. McNett, M. | Crit Care Nurse | 2020 | |
| Delirium after cardiac arrest: Phenotype, prediction, and outcome | Keijzer, H. M. Klop, M. van Putten, M. J. A. M. Hofmeijer, J. | Resuscitation | 2020 |
clonazepam |
| Acute Inflammation Alters Brain Energy Metabolism in Mice and Humans: Role in Suppressed Spontaneous Activity, Impaired Cognition, and Delirium | Kealy, J. Murray, C. Griffin, E. W. Lopez-Rodriguez, A. B. Healy, D. Tortorelli, L. S. Lowry, J. P. Watne, L. O. Cunningham, C. | J Neurosci | 2020 | |
| Incidental Durotomy is Associated with Increased Risk of Delirium in Patients Aged 65 and Older | Kazarian, E. R. Lopez, W. Y. Eizember, S. Blucher, J. A. Culley, D. J. Javedan, H. Kang, J. D. Schoenfeld, A. J. | Spine (Phila Pa 1976) | 2020 | |
| Scheduled intravenous acetaminophen versus nonsteroidal anti-inflammatory drugs (NSAIDs) for better short-term outcomes after esophagectomy for esophageal cancer | Kawakami, J. Abe, T. Higaki, E. Hosoi, T. Fukaya, M. Komori, K. Ito, S. Nakatochi, M. Nagino, M. Shimizu, Y. | Surg Today | 2020 |
Esophageal surgery |
| Experience of morphine therapy for refractory dyspnea as palliative care in advanced heart failure patients | Kawaguchi, J. Hamatani, Y. Hirayama, A. Nishimura, K. Nakai, E. Nakamura, E. Miyata, M. Kawano, Y. Takada, Y. Anchi, Y. Funabashi, S. Kuroda, K. Azechi, M. Takahama, H. Anzai, T. Yasuda, S. Kitaoka, H. Izumi, C. | J Cardiol | 2020 |
Dyspnea |
| Delirium and Developmental Disability: Improving Specificity of a Pediatric Delirium Screen∗ | Kaur, S. Silver, G. Samuels, S. Rosen, A. H. Weiss, M. Mauer, E. A. Gerber, L. M. Greenwald, B. M. Traube, C. | Pediatric Critical Care Medicine | 2020 |
article |
| Hyperactive Terminal Delirium in Hospice Patients: A Retrospective Cohort Study | Kates, J. | J Hosp Palliat Nurs | 2020 | |
| Incidence & Risk Factors of Postoperative Delirium After Spinal Surgery in Older Patients | Kang, T. Park, S. Y. Lee, J. H. Lee, S. H. Park, J. H. Kim, S. K. Suh, S. W. | Sci Rep | 2020 | |
| C-reactive protein to albumin ratio as a novel inflammatory biomarker for postoperative delirium in patients undergoing transcatheter aortic valve replacement | Kalyoncuoğlu, M. Biter, H. İ Durmuş, G. Baştan, B. Can, M. M. | Haseki Tip Bulteni | 2020 |
biological marker |
| Emergence delirium in children undergoing dental surgery under general anesthesia | Jooma, Z. Perrie, H. Scribante, J. Kleyenstuber, T. | Paediatr Anaesth | 2020 |
Paediatric Anesthesia Emergence Delirium score |
| Alteration of consciousness as initial presentation in COVID-19: Observation | Joob, B. Wiwanitkit, V. | Annals of Indian Academy of Neurology | 2020 |
altered state of consciousness |
| A systematic review of the impact of delirium on allied health interventions: A surprising lack of data | Johnson, D. Maylin, E. Hayes, L. Hair, C. Kraemer, T. Lau, M. Brodtmann, A. Sahathevan, R. | Neurology Asia | 2020 |
arthroplasty |
| Etiology, Clinical Profile and Outcome of Encephalopathy in Elderly | John, B. Loomba, V. John, M. | J Assoc Physicians India | 2020 |
Aged |
| Ultrasound-guided continuous thoracic paravertebral block alleviates postoperative delirium in elderly patients undergoing esophagectomy: A randomized controlled trial | Jin, L. Yao, R. Heng, L. Pang, B. Sun, F. G. Shen, Y. Zhong, J. F. Zhao, P. P. Wu, C. Y. Li, B. P. | Medicine (Baltimore) | 2020 |
Aged |
| Cognitive Impairment Level and Elderly Hip Fracture: Implications in Rehabilitation Nursing | Jiménez Mola, S. Calvo-Lobo, C. Idoate Gil, J. Seco Calvo, J. | Rehabil Nurs | 2020 |