NIDUS Delirium Bibliography

Delirium Bibliography books graphic What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

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Title: A Retrospective Study Establishing a Nomogram Predictive Model for Postoperative High-Activity Delirium After Non-Cardiac Surgery

Authors: Tu, Y. Du, W. Pan, Y. Zhang, X. Mo, Y. Sun, C. Wang, J.

Year: 2024

Journal: Neuropsychiatr Dis Treat

Abstract: BACKGROUND: Postoperative high-activity delirium (PDHA) manifests as a high alertness, restlessness, hallucinations, and delusions. Occurrence of PDHA represents an increased risk of poor prognosis for patients. OBJECTIVE: To establish and validate a nomogram prediction model for high-activity delirium after non-cardiac surgery in a post-anesthesia care unit (PACU). METHODS: This study retrospectively enrolled adult patients who underwent non-cardiac surgery and were observed in the PACU as training data. Patients were divided into PDHA (199 patients) and non-PDHA (396 patients) groups. Patients’ general data, preoperative indicators, intraoperative conditions, and postoperative PACU conditions were collected. The risk factors for PDHA were identified using univariate and multivariate logistic regression analyses. A predictive column chart was created using R language. Adult patients who underwent non-cardiac surgery and entered the PACU for observation were randomly selected as the validation set data (198 cases) for model performance validation. RESULTS: The incidence rate of adult PDHA in the PACU was 0.275%. Sex, age, smoking history, low preoperative albumin level, Society of Anesthesiologists (ASA) classification, anesthesia duration, and postoperative PACU pain score were independent risk factors for hyperactive delirium in PACU adults. In this study, an adult PACU PDHA nomogram prediction model was developed. The training dataset verified that the ROC curve (area under the curve) and 95% confidence interval (95% CI) were 0.936 (0.917-0.955). The ROC curve of the validation data row showed that the area under the curve and 95% CI were 0.926 (0.885-0.967). CONCLUSION: The nomogram predictive model for PACU adult high-activity delirium constructed in this study showed good predictive performance. This model could enable the visualization and graphical prediction of adult high-activity delirium occurrence after PACU, which has clinical value.

PMID: PMID: 39246738

PMCID: PMC11380854

Keywords: Pacu
delirium
nomograms
post anesthesia care unit
risk factor

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Total Records Found: 6289, showing 100 per page
Title	Authors	Journal	Year	Keywords
A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care	Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K.	Age Ageing	2020	delirium hospitals multicomponent interventions older people prevention
Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery	Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P.	American Journal of Medicine	2020	adult aged anticoagulation article California controlled study delirium drug therapy hip fracture human international normalized ratio length of stay male mortality multicenter study (topic) perioperative medicine preoperative evaluation surgery systematic review warfarin
Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients	Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H.	World Neurosurgery	2020	titanium cage liquid nitrogen tranexamic acid adult aged aged hospital patient article autograft bladder cancer breast cancer cancer of unknown primary site cancer prognosis cancer recurrence cerebellum hemorrhage cervical spine chondrosarcoma chylothorax computer assisted tomography corpectomy deep vein thrombosis distant metastasis female follow up Frankel grade functional status hemivertebrectomy human Kaplan Meier method leiomyosarcoma liquorrhea lung embolism major clinical study male middle aged neurological complication osteosarcoma overall survival peroperative complication pleura effusion pneumocephalus pneumothorax postoperative complication postoperative delirium preoperative evaluation renal cell carcinoma reoperation retrospective study sarcoma spinal cord infarction spinal cord ischemia spine metastasis spine radiography spine surgery subdural hematoma surgical approach surgical infection surgical technique survival analysis survival rate thoracolumbar spine thyroid cancer total en bloc spondylectomy vertebra body walking wound dehiscence
Risk factors for delirium in intensive care unit and its duration	Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W.	Zhonghua Wei Zhong Bing Ji Jiu Yi Xue	2020	sedative agent APACHE article artificial ventilation disease duration drug use female general anesthesia human hypoxia incidence intensive care psychosis intensive care unit length of stay major clinical study male risk factor screening sex difference spinal anesthesia treatment duration
Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials	Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P.	Sleep Med Rev	2020	Delirium Melatonin Melatonin agonist Prevention Ramelteon
Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial	Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L.	Medicine (United States)	2020	ChiCTR-INR-16009116 BCDB-100 electronic analgesia pump Datex-Ohmeda S/5 monitor monitor pump atropine cisatracurium hetastarch messenger RNA oxycodone oxygen propofol protein c fos remifentanil sufentanil adenotonsillar hypertrophy adenotonsillectomy analgesia analgesic activity article child continuous infusion controlled study drug efficacy electroencephalogram endoscopic plasma total adenotonsillectomy endoscopic surgery extubation Face Legs Activity Cry and Consolability score female follow up human major clinical study male nausea operation duration outcome assessment pediatric anesthesia Pediatric Anesthesia Emergence Delirium score postoperative analgesia postoperative pain postoperative period prediction preemptive analgesia preschool child priority journal probability protein blood level quantitative analysis randomized controlled trial real time polymerase chain reaction response entropy scoring system sleep disordered breathing stress
Delirium screening practice in specialist palliative care units: a survey	Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J.	BMJ Support Palliat Care	2020	delirium hospice care terminal care
Movements and trends in intensive care pain treatment and sedation: What matters to the patient?	Wøien, H.	J Clin Nurs	2020	Adult Aged Critical Care/ methods Delirium/prevention & control Female Guideline Adherence Humans Hypnotics and Sedatives/administration & dosage/ adverse effects Longitudinal Studies Male Middle Aged Pain/drug therapy Pain Management/ methods Prospective Studies Respiration, Artificial/methods analgosedation critically ill delirium implementation intensive care pain sedation
Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications	Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J.	Am J Surg	2020	Antipsychotic Agents/ adverse effects Critical Illness Delirium/ drug therapy/ etiology Female Humans Intensive Care Units Lung Diseases/ chemically induced Male Middle Aged Quetiapine Fumarate/ adverse effects Retrospective Studies Risk Factors Trauma Centers Wounds and Injuries/ complications Delirium Pulmonary complications Quetiapine Sedation Trauma
Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery	Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D.	Acta Anaesthesiol Scand	2020
The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study	Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P.	Palliat Med	2020	Delirium hospitalization prevalence retrospective studies risk factors terminal care
Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach?	Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm	J Clin Nurs	2020	Aged Aged, 80 and over Female Frailty/ diagnosis/mortality Geriatric Assessment/ methods Humans Male Mass Screening/ methods Patient Readmission/statistics & numerical data Predictive Value of Tests ROC Curve Retrospective Studies Risk Assessment/methods feasibility frailty frailty screening geriatric assessment hospitalised patients nursing assessment risk screening safety programme validity
Predicting postoperative delirium after microvascular decompression surgery with machine learning	Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J.	J Clin Anesth	2020	Machine learning Microvascular decompression Postoperative delirium
Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System	Wang, X. Li, L. Wang, L. Feng, W. Zhang, P.	Statistics in Medicine	2020	amfebutamone bevacizumab bimatoprost budesonide bupivacaine carboplatin carvedilol duloxetine escitalopram filgrastim gemcitabine lamotrigine metaxalone methamphetamine naloxone parathyroid hormone[1-34] pegfilgrastim phenytoin prednisone rofecoxib rosiglitazone rosuvastatin telmisartan tetracycline unindexed drug valdecoxib valproic acid varenicline warfarin zoledronic acid adverse outcome analytic method article comparative study controlled study data analysis data mining delirium disease association drug potentiation false positive result human mathematical model neuropathy risk factor signal detection simulation
Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery	Wang, L. Zhang, T. Huang, L. Peng, W.	Biomed Res Int	2020
Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial	Wang, L. Huang, L. Zhang, T. Peng, W.	Biomed Res Int	2020
Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study	Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G.	J Affect Disord	2020	Cognition Magnetic seizure therapy Major depressive disorder
Development and validation of the delirium risk assessment score (DRAS)	Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J.	Eur Geriatr Med	2020	Delirium Predisposing risk factors Prevention Risk assessment Screening instrument
Development and validation of the delirium risk assessment score (DRAS)	Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J.	Eur Geriatr Med	2020	Delirium Predisposing risk factors Prevention Risk assessment Screening instrument
Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience	Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B.	Gastroenterology Report	2020	politef implant stent graft TIPS endoprosthesis lactulose politef rifaximin abdominal pain abdominal wall hernia adult alcohol liver disease article ascites clinical outcome combination drug therapy confusion controlled study electronic medical record female hepatic encephalopathy hospital readmission human hypervolemia longitudinal study major clinical study male medical record review middle aged Model For End Stage Liver Disease Score nonalcoholic steatohepatitis pancreatitis postoperative hemorrhage postoperative infection postoperative nausea and vomiting postoperative pain priority journal retrospective study transjugular intrahepatic portosystemic shunt
Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study	Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C.	Eur J Intern Med	2020	Anticholinergics Cohort studies Critical care Delirium Intensive care Survival analysis
Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome	von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J.	Neurocrit Care	2020	Cam-icu Delirium Icdsc Neurocritical care Stroke
Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism	Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F.	Pharmacotherapy	2020	critical care delirium metabolomics surgery
Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study	Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z.	Journal of Cardiothoracic and Vascular Anesthesia	2020	adult article cardiopulmonary bypass cohort analysis controlled study coronary artery bypass surgery female human human tissue intensive care unit major clinical study male postoperative delirium prospective study risk factor surgery university hospital vitamin D deficiency vitamin D
New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study	Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N.	Dement Geriatr Cogn Disord	2020	Delirium Delirium severity Psychometrics
A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM)	Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M.	J Am Geriatr Soc	2020
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital	Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S.	Age Ageing	2020	acute delirium digital electronic health record older people quality improvement
Registration of attentional function as a predictor of incident delirium (the RAPID study)	van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N.	Alzheimers Dement (N Y)	2020	attentional function attentional impairments consciousness elective major surgery postoperative delirium
Predisposition for delirium and EEG characteristics	van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C.	Clin Neurophysiol	2020	Delirium Eeg Functional connectivity Functional impairment Graph analysis Risk factors
Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation	van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C.	Journal of Thoracic and Cardiovascular Surgery	2020	aged article clinical assessment controlled study facilitation female frailty geriatric assessment geriatrician high risk patient hospitalization human long term survival major clinical study male mortality multicenter study postoperative delirium prediction prospective study risk assessment transcatheter aortic valve implantation very elderly
Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial	Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B.	Injury	2020	aged analgesia anemia article clinical trial complication constipation controlled study dementia drug therapy DSM-IV-TR female femoral nerve geriatrics hip fracture hospitalization human incidence major clinical study male nerve block nurse nutritional disorder peripheral nerve postoperative delirium randomized controlled trial surgery urinary tract infection very elderly opiate
Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age	Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K.	Heart Surg Forum	2020
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography	Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P.	Intensive Care Medicine	2020	adult anesthesia article cardiac surgery intensive care unit controlled study delirium electroencephalography monitoring female human incidence major clinical study male neurologist observational study pilot study postoperative care prevalence prospective study retrospective study seizure single blind procedure surgery theta rhythm valve
Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium	Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M.	J Crit Care	2020	Delirium Haloperidol Intensive care Pharmacodynamics Pharmacogenetics Pharmacokinetics
The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial	Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J.	Geriatr Orthop Surg Rehabil	2020	acute pain medicine adult reconstructive surgery anesthesia geriatric medicine music therapy regional anesthesia
The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study	Tong, C. Huang, C. Wu, J. Xu, M. Cao, H.	J Cardiothorac Vasc Anesth	2020	Mild cognitive impairment Postoperative delirium Postoperative pulmonary complications Thoracic surgery
Development of a Palliative Care Toolkit for the COVID-19 Pandemic	Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J.	Journal of pain and symptom management	2020	adult article communication skill controlled study conversation coronavirus disease 2019 critically ill patient delirium dyspnea evidence based practice center hospitalization human nurse practitioner pain palliative therapy pandemic videorecording
Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis	Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V.	J Am Med Dir Assoc	2020	Aging comprehensive geriatric assessment delirium functional status outcomes surgery
Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study	Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E.	Saudi Journal of Anaesthesia	2020	laryngeal mask propofol sevoflurane adverse drug reaction airway obstruction anesthesia complication anesthesia induction anesthetic recovery article bradycardia child clinical outcome cohort analysis controlled study disease re-emergence emergence agitation female health care human inhalation anesthesia larynx spasm major clinical study male nausea nuclear magnetic resonance imaging observational study oxygen desaturation pediatric anesthesia preschool child priority journal prospective study sedation side effect timeliness vomiting
Atypical presentation of COVID-19 in a frail older person	Tay, H. S. Harwood, R.	Age Ageing	2020	Covid-19 atypical presentation older people pandemic pneumonia
ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery	Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M.	Anesth Analg	2020
Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery	Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X.	Biosci Rep	2020	Dexmedetomidine delirium inflammatory response patient-controlled analgesia postoperative pain thoracoscopic-laparoscopic esophagectomy
Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity	Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D.	Br J Anaesth	2020	cognitive dysfunction connectivity delirium electroencephalogram inflammation mechanism postoperative slow wave activity surgery
Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients	Tan, C. Saito, N. Miyawaki, I. Shiotani, H.	Chronobiol Int	2020	Postoperative delirium circadian rhythm cosine periodic regression analysis physical activity
Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan	Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y.	Current Medical Research and Opinion	2020	hypnotic agent suvorexant abdominal discomfort adult aged article asthenia attention disturbance bipolar disorder brain hemorrhage clinical practice cognitive defect cold sweat comorbidity delirium depression diarrhea dizziness drug efficacy drug eruption drug safety edema face edema female femoral neck fracture hallucination hot flush human hypersalivation insomnia internal medicine Japan major clinical study male mental disease night sweat pollakisuria postmarketing surveillance pruritus rash schizophrenia self evaluation sleep disordered breathing somnolence subdural hematoma suicidal ideation visual hallucination
Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis	Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W.	Anesth Analg	2020
Risk and Consequences of Postoperative Delirium in Cardiac Surgery	Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H.	Thorac Cardiovasc Surg	2020
Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study	Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C.	J Am Med Dir Assoc	2020	Hip fracture falls dementia mental illness schizophrenia substance use disorder
Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study	Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A.	JACCP Journal of the American College of Clinical Pharmacy	2020	adult article controlled study coronary care unit delirium demography drug therapy drug withdrawal female gender hospital discharge human incidence length of stay major clinical study male outcome assessment pharmacist psychosis QT prolongation QTc interval quasi experimental study rank sum test retrospective study neuroleptic agent
Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review	Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L.	J Clin Nurs	2020	In-hospital fall cognitive impairment delirium dementia prevention
Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care	Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M.	Crit Care Nurse	2020
Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX)	Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A.	Pediatr Crit Care Med	2020
Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial	Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J.	Br J Anaesth	2020	awareness benzodiazepines cardiac anaesthesia delirium pilot study pragmatic randomised cluster crossover
Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital	Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R.	Minerva Anestesiol	2020
Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis	Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F.	Medicine (Baltimore)	2020	Apache Academic Medical Centers Aged Biomarkers C-Reactive Protein/analysis Cluster Analysis Coma/ epidemiology Comorbidity Delirium/ epidemiology Female Humans Hypnotics and Sedatives/administration & dosage Intensive Care Units/ statistics & numerical data Male Middle Aged Phenotype Prospective Studies Respiration, Artificial/ statistics & numerical data Risk Assessment Risk Factors Sepsis/epidemiology Socioeconomic Factors Time Factors
Validation of a multidisciplinary care protocol for critically ill patients with delirium	Souza, T. L. Azzolin, K. O. Souza, E. N.	Revista gaucha de enfermagem	2020	adult agitation analgesia article clinical outcome consensus content validity critically ill patient delirium human intensive care unit mobilization outcome assessment sedation sleep validation process
Hospital Costs and Reimbursement Model for a Geriatric Emergency Department	Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G.	Acad Emerg Med	2020
Natural light exposure and delirium in ICU: does the dark side cloud everything?	Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F.	Annals of Intensive Care	2020	sedative agent adult respiratory distress syndrome anxiety critically ill patient depression hallucination hospital admission human hypoxemia incidence intensive care intensive care psychosis intensive care unit letter light exposure phenotype priority journal risk reduction sepsis survivor
Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review	Soleman, J. Guzman, R.	Behavioural Neurology	2020	rigid endoscope arachnoid cyst brain damage brain fornix brain third ventricle brain ventricle brain ventricle tumor choroid plexus tumor clinical outcome cognition assessment cognitive defect colloid cyst confusion depressive psychosis emotional disorder executive function follow up human hydrocephalus memory disorder mental deterioration mental disease morbidity neuroendoscopy neurological complication neuropsychological test organic psychosyndrome personality disorder postoperative cognitive dysfunction postoperative complication postoperative period preoperative period review systematic review ventricular neuroendoscopy
Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial	Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J.	Age Ageing	2020	delirium prevention intervention fidelity multi-component intervention older people
Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation	Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M.	Int J Artif Organs	2020	Extracorporeal membrane oxygenation analgesics sedation sedatives
Are Antipsychotics Helpful for Preventing or Treating Delirium?	Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M.	J Gerontol Nurs	2020
Family caregiver's experience of caring for an older adult with delirium: A systematic review	Shrestha, P. Fick, D. M.	Int J Older People Nurs	2020	delirium delirium superimposed on dementia experience family caregivers older adults systematic review
Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis	Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z.	Clin Exp Pharmacol Physiol	2020	dexmedetomidine non-cardiac surgery postoperative delirium
Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery	Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z.	J Int Med Res	2020	Postoperative delirium abdominal surgery anesthesia cognitive status melatonin older patient
Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation	Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S.	J Am Geriatr Soc	2020	dementia inpatient palliative care
Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain"	Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L.	Anesth Analg	2020
Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation	Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M.	Catheter Cardiovasc Interv	2020	Nirs Tavi aortic stenosis delirium stroke
Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration	Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A.	Pediatric Dental Journal	2020	propofol anesthesia induction article body temperature child childhood disease dental patient dental procedure emergence agitation extubation female general anesthesia heart rate hemodynamics human intubation major clinical study male oxygen saturation priority journal retrospective study single drug dose
Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis	Segers, K. Benoit, F. Meyts, J. M. Surquin, M.	Psychogeriatrics	2020	Alzheimerʼs disease Lewy body disease anxiety dementia dementia with Lewy bodies
Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU	Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R.	Crit Care Explor	2020	benzodiazepines critical care delirium dexmedetomidine mechanical ventilation sedation
Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study	Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E.	Crit Care Explor	2020	benzodiazepine benzodiazepine antagonist critical care delirium flumazenil hypoactive delirium
Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database	Sato, K. Mano, T. Iwata, A. Toda, T.	Biosci Trends	2020	Adverse Drug Reaction Reporting Systems Aged Betacoronavirus/isolation & purification Chloroquine/administration & dosage/ adverse effects Databases, Factual Female Humans Male Mental Disorders/ chemically induced Middle Aged Neurotoxicity Syndromes/ etiology Pharmacovigilance Retrospective Studies United States United States Food and Drug Administration Covid-19 Faers adverse events chloroquine real-world data
Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery	Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A.	Cir Esp	2020	Ancianos Cirugía abdominal Cirugía urgente Delirium Postoperative complications Síndrome confusional agudo Urgent abdominal surgery
Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery	Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A.	Cir Esp	2020	Ancianos Cirugía abdominal Cirugía urgente Delirium Postoperative complications Síndrome confusional agudo Urgent abdominal surgery
Non-pharmacological approaches in the prevention of delirium	Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A.	European Geriatric Medicine	2020	psychotropic agent clinical practice delirium geriatric patient hospitalization human outcome assessment phototherapy priority journal review surgical patient
Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study	Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K.	Medicina (Kaunas)	2020	biomarker cardiac surgery delirium natriuretic peptide off-pump surgery
Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery	Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B.	J Am Coll Surg	2020
Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta	Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A.	Egypt Heart J	2020	Aging Delirium Genome-wide DNA methylation Immune response Inflammatory response
Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients	Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G.	J Psychiatr Res	2020	Aging Delirium Genome-wide DNA methylation Immune response Inflammatory response
Major surgery induces acute changes in measured DNA methylation associated with immune response pathways	Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J.	Sci Rep	2020
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period	Rostoft, S. Hamaker, M. E.	Eur J Surg Oncol	2020	Cognition Colorectal cancer Frailty Functional status Geriatric assessment Preoperative evaluation
The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review	Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M.	Age Ageing	2020	delirium hospital older people outcomes severity
Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review	Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V.	Crit Care Med	2020
Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal	Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L.	Minerva Anestesiol	2020
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic	Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S.	Lancet Psychiatry	2020	Coronavirus Infections/ complications Fatigue/ etiology Humans Mental Disorders/ etiology Nervous System Diseases/ etiology Pandemics Pneumonia, Viral/ complications Severe Acute Respiratory Syndrome/ complications
Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis	Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M.	Acta Neuropsychiatr	2020	anti-N-methyl-D-aspartate receptor encephalitis diagnosis differential neuropsychiatry psychoneuroimmunology
Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis	Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M.	Gen Hosp Psychiatry	2020	Anti-NMDA receptor encephalitis Autoimmune encephalitis Catatonia Delirium Mania
Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit	Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F.	Zhonghua Wei Zhong Bing Ji Jiu Yi Xue	2020	sedative agent anterior cingulate article brain damage brain function brain region caudate nucleus cerebellum clinical article controlled study corpus callosum corpus striatum delirium diffusion tensor imaging drug use educational status fractional anisotropy frontal lobe functional magnetic resonance imaging hospital admission human inferior frontal gyrus insula intensive care psychosis intensive care unit left hippocampus mean diffusivity mesencephalon middle frontal gyrus morphology parietal lobe pons right hippocampus superior frontal gyrus temporal lobe
Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study	Rásky, É Stolz, E. Jagsch, C.	Neuropsychiatrie	2020	article Austria controlled study female gerontopsychiatry human major clinical study male mortality retrospective study
Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital	Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F.	Aust Crit Care	2020	Intensive care Post–intensive care syndrome Rehabilitation Survivorship
Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery	Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C.	Journal of Alzheimer's Disease	2020	aged aging Alzheimer disease article brain atrophy brain cortex cognition cognitive defect cohort analysis cortical thickness (brain) disease association elective surgery female follow up Hopkins verbal learning test human major clinical study male neuroimaging nuclear magnetic resonance imaging postoperative delirium preoperative evaluation priority journal risk factor surgical patient trail making test verbal learning
Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service	Quante, A. Schulz, K. Fissler, M.	Wiener Medizinische Wochenschrift	2020	adult article cancer patient comorbidity consultation controlled study delirium demography depression drug therapy female general hospital hospital patient human lung cancer major clinical study male psychiatric diagnosis psychiatrist psychotherapy retrospective study antidepressant agent
Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis	Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W.	Cardiovasc Interv Ther	2020	Delirium Meta-analysis Mortality Systematic reviews Transcatheter aortic valve replacement
A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer	Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L.	J Geriatr Oncol	2020	Functional decline Geriatric assessment Geriatric complications Postoperative complications
Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study	Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G.	Eur J Anaesthesiol	2020
Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease	Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F.	Brain Behav Immun	2020	Alzheimer’s disease Delirium Infection cerebrospinal fluid homeostatic microglial control synapse
Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria	Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M.	Infect Control Hosp Epidemiol	2020
Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials	Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H.	J Cardiothorac Vasc Anesth	2020	acute kidney injury cardiac surgery dexmedetomidine meta-analysis trial sequential analysis
Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium	Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O.	Anesthesiology	2020