Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Diurnal variation of postoperative delirium in elderly patients undergoing esketamine anesthesia for elective noncardiac surgery: a randomized clinical trial
Authors
Zhang, Y. Chen, R. Tang, S. Sun, T. Yu, Y. Shi, R. Wang, K. Zeng, Z. Liu, X. Meng, Q. Xia, Z.
Year
2024
Journal
Int J Surg
Abstract

BACKGROUND: Postoperative delirium (POD) is a serious and common complication. The aim of present study is to investigate the diurnal variation of POD and the effects of esketamine in elderly patients. METHODS: A randomized, double-blind, placebo-controlled clinical trial with factorial design was conducted. Patients (aged 65 to 85 years) with normal Mini-Mental State Examination (MMSE) score were stratified by age (≤70 vs. >70) and American Society of Anesthesiologists physical status classification (Ⅱ vs. Ⅲ), then randomly assigned to either morning (08:00-12:00) or afternoon (14:00-18:00) noncardiac operation under general anesthesia with or without esketamine administration (0.2 mg/kg). The primary outcome was the incidence of POD (3-Minute Diagnostic Interview for Confusion Assessment Method-defined Delirium, 3D-CAM) on postoperative days 1, 3, and 7. The secondary outcomes were the scores of MMSE and Hospital Anxiety and Depression Scale. The intention-to-treat analysis of the outcomes were performed by generalized estimating equation. RESULTS: Six patients who did not receive an intervention because of canceled operation were excluded after randomization. The datasets containing 426 cases were analyzed following the intention-to-treat principle after handling missing data via multiple imputation method. The incidence of POD declined from about 55% on postoperative day 1 to 31 and 18% on postoperative days 3 and 7, respectively. Afternoon operation [B=-0.583, OR (95% CI) 0.558 (0.319-0.976); P=0.041], but not esketamine, significantly decreased the incidence of POD. Both esketamine and operation time failed to significantly affect MMSE, HAD, and NRS score. There was no interaction among operation time, esketamine, and follow up time. CONCLUSION: Elderly patients undergoing elective noncardiac surgery in the afternoon displayed lower POD incidence than those operated in the morning. A single low-dose of esketamine before general anesthesia induction failed to significantly decrease the risk of POD but decrease the risk of intraoperative hypotension and emergence agitation.

PMID

PMID: 39275772

PMCID: PMC11392167

Keywords

Humans
*Ketamine/administration & dosage
Aged
Female
Male
Double-Blind Method
Aged, 80 and over
*Elective Surgical Procedures/adverse effects
*Postoperative Complications/prevention & control/epidemiology
Anesthesia, General/adverse effects
Circadian Rhythm
Delirium/prevention & control/epidemiology/diagnosis
Emergence Delirium/prevention & control/epidemiology/diagnosis

Page(s)
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Development and validation of the delirium risk assessment score (DRAS) Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. Eur Geriatr Med 2020

Delirium
Predisposing risk factors
Prevention
Risk assessment
Screening instrument

Development and validation of the delirium risk assessment score (DRAS) Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. Eur Geriatr Med 2020

Delirium
Predisposing risk factors
Prevention
Risk assessment
Screening instrument

Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. Gastroenterology Report 2020

politef implant
stent graft
TIPS endoprosthesis
lactulose
politef
rifaximin
abdominal pain
abdominal wall hernia
adult
alcohol liver disease
article
ascites
clinical outcome
combination drug therapy
confusion
controlled study
electronic medical record
female
hepatic encephalopathy
hospital readmission
human
hypervolemia
longitudinal study
major clinical study
male
medical record review
middle aged
Model For End Stage Liver Disease Score
nonalcoholic steatohepatitis
pancreatitis
postoperative hemorrhage
postoperative infection
postoperative nausea and vomiting
postoperative pain
priority journal
retrospective study
transjugular intrahepatic portosystemic shunt

Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. Eur J Intern Med 2020

Anticholinergics
Cohort studies
Critical care
Delirium
Intensive care
Survival analysis

Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. Neurocrit Care 2020

Cam-icu
Delirium
Icdsc
Neurocritical care
Stroke

Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. Pharmacotherapy 2020

critical care
delirium
metabolomics
surgery

Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. Journal of Cardiothoracic and Vascular Anesthesia 2020

adult
article
cardiopulmonary bypass
cohort analysis
controlled study
coronary artery bypass surgery
female
human
human tissue
intensive care unit
major clinical study
male
postoperative delirium
prospective study
risk factor
surgery
university hospital
vitamin D deficiency
vitamin D

New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. Dement Geriatr Cogn Disord 2020

Delirium
Delirium severity
Psychometrics

A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. J Am Geriatr Soc 2020
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. Age Ageing 2020

acute
delirium
digital
electronic health record
older people
quality improvement

Registration of attentional function as a predictor of incident delirium (the RAPID study) van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. Alzheimers Dement (N Y) 2020

attentional function
attentional impairments
consciousness
elective major surgery
postoperative delirium

Predisposition for delirium and EEG characteristics van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. Clin Neurophysiol 2020

Delirium
Eeg
Functional connectivity
Functional impairment
Graph analysis
Risk factors

Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. Journal of Thoracic and Cardiovascular Surgery 2020

aged
article
clinical assessment
controlled study
facilitation
female
frailty
geriatric assessment
geriatrician
high risk patient
hospitalization
human
long term survival
major clinical study
male
mortality
multicenter study
postoperative delirium
prediction
prospective study
risk assessment
transcatheter aortic valve implantation
very elderly

Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. Injury 2020

aged
analgesia
anemia
article
clinical trial
complication
constipation
controlled study
dementia
drug therapy
DSM-IV-TR
female
femoral nerve
geriatrics
hip fracture
hospitalization
human
incidence
major clinical study
male
nerve block
nurse
nutritional disorder
peripheral nerve
postoperative delirium
randomized controlled trial
surgery
urinary tract infection
very elderly
opiate

Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. Heart Surg Forum 2020
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. Intensive Care Medicine 2020

adult
anesthesia
article
cardiac surgery intensive care unit
controlled study
delirium
electroencephalography monitoring
female
human
incidence
major clinical study
male
neurologist
observational study
pilot study
postoperative care
prevalence
prospective study
retrospective study
seizure
single blind procedure
surgery
theta rhythm
valve

Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. J Crit Care 2020

Delirium
Haloperidol
Intensive care
Pharmacodynamics
Pharmacogenetics
Pharmacokinetics

The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. Geriatr Orthop Surg Rehabil 2020

acute pain medicine
adult reconstructive surgery
anesthesia
geriatric medicine
music therapy
regional anesthesia

The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. J Cardiothorac Vasc Anesth 2020

Mild cognitive impairment
Postoperative delirium
Postoperative pulmonary complications
Thoracic surgery

Development of a Palliative Care Toolkit for the COVID-19 Pandemic Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. Journal of pain and symptom management 2020

adult
article
communication skill
controlled study
conversation
coronavirus disease 2019
critically ill patient
delirium
dyspnea
evidence based practice center
hospitalization
human
nurse practitioner
pain
palliative therapy
pandemic
videorecording

Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. J Am Med Dir Assoc 2020

Aging
comprehensive geriatric assessment
delirium
functional status
outcomes
surgery

Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. Saudi Journal of Anaesthesia 2020

laryngeal mask
propofol
sevoflurane
adverse drug reaction
airway obstruction
anesthesia complication
anesthesia induction
anesthetic recovery
article
bradycardia
child
clinical outcome
cohort analysis
controlled study
disease re-emergence
emergence agitation
female
health care
human
inhalation anesthesia
larynx spasm
major clinical study
male
nausea
nuclear magnetic resonance imaging
observational study
oxygen desaturation
pediatric anesthesia
preschool child
priority journal
prospective study
sedation
side effect
timeliness
vomiting

Atypical presentation of COVID-19 in a frail older person Tay, H. S. Harwood, R. Age Ageing 2020

Covid-19
atypical presentation
older people
pandemic
pneumonia

ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M. Anesth Analg 2020
Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X. Biosci Rep 2020

Dexmedetomidine
delirium
inflammatory response
patient-controlled analgesia
postoperative pain
thoracoscopic-laparoscopic esophagectomy

Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. Br J Anaesth 2020

cognitive dysfunction
connectivity
delirium
electroencephalogram
inflammation
mechanism
postoperative
slow wave activity
surgery

Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients Tan, C. Saito, N. Miyawaki, I. Shiotani, H. Chronobiol Int 2020

Postoperative delirium
circadian rhythm
cosine
periodic regression analysis
physical activity

Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. Current Medical Research and Opinion 2020

hypnotic agent
suvorexant
abdominal discomfort
adult
aged
article
asthenia
attention disturbance
bipolar disorder
brain hemorrhage
clinical practice
cognitive defect
cold sweat
comorbidity
delirium
depression
diarrhea
dizziness
drug efficacy
drug eruption
drug safety
edema
face edema
female
femoral neck fracture
hallucination
hot flush
human
hypersalivation
insomnia
internal medicine
Japan
major clinical study
male
mental disease
night sweat
pollakisuria
postmarketing surveillance
pruritus
rash
schizophrenia
self evaluation
sleep disordered breathing
somnolence
subdural hematoma
suicidal ideation
visual hallucination

Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. Anesth Analg 2020
Risk and Consequences of Postoperative Delirium in Cardiac Surgery Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. Thorac Cardiovasc Surg 2020
Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. J Am Med Dir Assoc 2020

Hip fracture
falls dementia
mental illness
schizophrenia
substance use disorder

Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. JACCP Journal of the American College of Clinical Pharmacy 2020

adult
article
controlled study
coronary care unit
delirium
demography
drug therapy
drug withdrawal
female
gender
hospital discharge
human
incidence
length of stay
major clinical study
male
outcome assessment
pharmacist
psychosis
QT prolongation
QTc interval
quasi experimental study
rank sum test
retrospective study
neuroleptic agent

Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. J Clin Nurs 2020

In-hospital fall
cognitive impairment
delirium
dementia
prevention

Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. Crit Care Nurse 2020
Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. Pediatr Crit Care Med 2020
Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. Br J Anaesth 2020

awareness
benzodiazepines
cardiac anaesthesia
delirium
pilot study
pragmatic
randomised cluster crossover

Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. Minerva Anestesiol 2020
Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. Medicine (Baltimore) 2020

Apache
Academic Medical Centers
Aged
Biomarkers
C-Reactive Protein/analysis
Cluster Analysis
Coma/ epidemiology
Comorbidity
Delirium/ epidemiology
Female
Humans
Hypnotics and Sedatives/administration & dosage
Intensive Care Units/ statistics & numerical data
Male
Middle Aged
Phenotype
Prospective Studies
Respiration, Artificial/ statistics & numerical data
Risk Assessment
Risk Factors
Sepsis/epidemiology
Socioeconomic Factors
Time Factors

Validation of a multidisciplinary care protocol for critically ill patients with delirium Souza, T. L. Azzolin, K. O. Souza, E. N. Revista gaucha de enfermagem 2020

adult
agitation
analgesia
article
clinical outcome
consensus
content validity
critically ill patient
delirium
human
intensive care unit
mobilization
outcome assessment
sedation
sleep
validation process

Hospital Costs and Reimbursement Model for a Geriatric Emergency Department Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. Acad Emerg Med 2020
Natural light exposure and delirium in ICU: does the dark side cloud everything? Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. Annals of Intensive Care 2020

sedative agent
adult respiratory distress syndrome
anxiety
critically ill patient
depression
hallucination
hospital admission
human
hypoxemia
incidence
intensive care
intensive care psychosis
intensive care unit
letter
light exposure
phenotype
priority journal
risk reduction
sepsis
survivor

Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review Soleman, J. Guzman, R. Behavioural Neurology 2020

rigid endoscope
arachnoid cyst
brain damage
brain fornix
brain third ventricle
brain ventricle
brain ventricle tumor
choroid plexus tumor
clinical outcome
cognition assessment
cognitive defect
colloid cyst
confusion
depressive psychosis
emotional disorder
executive function
follow up
human
hydrocephalus
memory disorder
mental deterioration
mental disease
morbidity
neuroendoscopy
neurological complication
neuropsychological test
organic psychosyndrome
personality disorder
postoperative cognitive dysfunction
postoperative complication
postoperative period
preoperative period
review
systematic review
ventricular neuroendoscopy

Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J. Age Ageing 2020

delirium prevention
intervention fidelity
multi-component intervention
older people

Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M. Int J Artif Organs 2020

Extracorporeal membrane oxygenation
analgesics
sedation
sedatives

Are Antipsychotics Helpful for Preventing or Treating Delirium? Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M. J Gerontol Nurs 2020
Family caregiver's experience of caring for an older adult with delirium: A systematic review Shrestha, P. Fick, D. M. Int J Older People Nurs 2020

delirium
delirium superimposed on dementia
experience
family caregivers
older adults
systematic review

Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z. Clin Exp Pharmacol Physiol 2020

dexmedetomidine
non-cardiac surgery
postoperative delirium

Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z. J Int Med Res 2020

Postoperative delirium
abdominal surgery
anesthesia
cognitive status
melatonin
older patient

Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S. J Am Geriatr Soc 2020

dementia
inpatient
palliative care

Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain" Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L. Anesth Analg 2020
Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M. Catheter Cardiovasc Interv 2020

Nirs
Tavi
aortic stenosis
delirium
stroke

Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A. Pediatric Dental Journal 2020

propofol
anesthesia induction
article
body temperature
child
childhood disease
dental patient
dental procedure
emergence agitation
extubation
female
general anesthesia
heart rate
hemodynamics
human
intubation
major clinical study
male
oxygen saturation
priority journal
retrospective study
single drug dose

Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis Segers, K. Benoit, F. Meyts, J. M. Surquin, M. Psychogeriatrics 2020

Alzheimerʼs disease
Lewy body disease
anxiety
dementia
dementia with Lewy bodies

Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R. Crit Care Explor 2020

benzodiazepines
critical care
delirium
dexmedetomidine
mechanical ventilation
sedation

Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. Crit Care Explor 2020

benzodiazepine
benzodiazepine antagonist
critical care
delirium
flumazenil
hypoactive delirium

Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database Sato, K. Mano, T. Iwata, A. Toda, T. Biosci Trends 2020

Adverse Drug Reaction Reporting Systems
Aged
Betacoronavirus/isolation & purification
Chloroquine/administration & dosage/ adverse effects
Databases, Factual
Female
Humans
Male
Mental Disorders/ chemically induced
Middle Aged
Neurotoxicity Syndromes/ etiology
Pharmacovigilance
Retrospective Studies
United States
United States Food and Drug Administration
Covid-19
Faers
adverse events
chloroquine
real-world data

Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. Cir Esp 2020

Ancianos
Cirugía abdominal
Cirugía urgente
Delirium
Postoperative complications
Síndrome confusional agudo
Urgent abdominal surgery

Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. Cir Esp 2020

Ancianos
Cirugía abdominal
Cirugía urgente
Delirium
Postoperative complications
Síndrome confusional agudo
Urgent abdominal surgery

Non-pharmacological approaches in the prevention of delirium Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. European Geriatric Medicine 2020

psychotropic agent
clinical practice
delirium
geriatric patient
hospitalization
human
outcome assessment
phototherapy
priority journal
review
surgical patient

Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. Medicina (Kaunas) 2020

biomarker
cardiac surgery
delirium
natriuretic peptide
off-pump surgery

Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. J Am Coll Surg 2020
Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. Egypt Heart J 2020

Aging
Delirium
Genome-wide DNA methylation
Immune response
Inflammatory response

Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. J Psychiatr Res 2020

Aging
Delirium
Genome-wide DNA methylation
Immune response
Inflammatory response

Major surgery induces acute changes in measured DNA methylation associated with immune response pathways Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. Sci Rep 2020
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period Rostoft, S. Hamaker, M. E. Eur J Surg Oncol 2020

Cognition
Colorectal cancer
Frailty
Functional status
Geriatric assessment
Preoperative evaluation

The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. Age Ageing 2020

delirium
hospital
older people
outcomes
severity

Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. Crit Care Med 2020
Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. Minerva Anestesiol 2020
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. Lancet Psychiatry 2020

Coronavirus Infections/ complications
Fatigue/ etiology
Humans
Mental Disorders/ etiology
Nervous System Diseases/ etiology
Pandemics
Pneumonia, Viral/ complications
Severe Acute Respiratory Syndrome/ complications

Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. Acta Neuropsychiatr 2020

anti-N-methyl-D-aspartate receptor encephalitis
diagnosis
differential
neuropsychiatry
psychoneuroimmunology

Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. Gen Hosp Psychiatry 2020

Anti-NMDA receptor encephalitis
Autoimmune encephalitis
Catatonia
Delirium
Mania

Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020

sedative agent
anterior cingulate
article
brain damage
brain function
brain region
caudate nucleus
cerebellum
clinical article
controlled study
corpus callosum
corpus striatum
delirium
diffusion tensor imaging
drug use
educational status
fractional anisotropy
frontal lobe
functional magnetic resonance imaging
hospital admission
human
inferior frontal gyrus
insula
intensive care psychosis
intensive care unit
left hippocampus
mean diffusivity
mesencephalon
middle frontal gyrus
morphology
parietal lobe
pons
right hippocampus
superior frontal gyrus
temporal lobe

Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study Rásky, É Stolz, E. Jagsch, C. Neuropsychiatrie 2020

article
Austria
controlled study
female
gerontopsychiatry
human
major clinical study
male
mortality
retrospective study

Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F. Aust Crit Care 2020

Intensive care
Post–intensive care syndrome
Rehabilitation
Survivorship

Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C. Journal of Alzheimer's Disease 2020

aged
aging
Alzheimer disease
article
brain atrophy
brain cortex
cognition
cognitive defect
cohort analysis
cortical thickness (brain)
disease association
elective surgery
female
follow up
Hopkins verbal learning test
human
major clinical study
male
neuroimaging
nuclear magnetic resonance imaging
postoperative delirium
preoperative evaluation
priority journal
risk factor
surgical patient
trail making test
verbal learning

Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service Quante, A. Schulz, K. Fissler, M. Wiener Medizinische Wochenschrift 2020

adult
article
cancer patient
comorbidity
consultation
controlled study
delirium
demography
depression
drug therapy
female
general hospital
hospital patient
human
lung cancer
major clinical study
male
psychiatric diagnosis
psychiatrist
psychotherapy
retrospective study
antidepressant agent

Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W. Cardiovasc Interv Ther 2020

Delirium
Meta-analysis
Mortality
Systematic reviews
Transcatheter aortic valve replacement

A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L. J Geriatr Oncol 2020

Functional decline
Geriatric assessment
Geriatric complications
Postoperative complications

Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G. Eur J Anaesthesiol 2020
Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F. Brain Behav Immun 2020

Alzheimer’s disease
Delirium
Infection
cerebrospinal fluid
homeostatic microglial control
synapse

Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M. Infect Control Hosp Epidemiol 2020
Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H. J Cardiothorac Vasc Anesth 2020

acute kidney injury
cardiac surgery
dexmedetomidine
meta-analysis
trial sequential analysis

Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O. Anesthesiology 2020
Evaluating delirium outcomes among older adults in the surgical intensive care unit Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. Heart Lung 2020

Critical care
Delirium
Elderly
Intensive care
Length of stay
Mortality
Older adult
Readmissions
Sicu

Association between continuous deep sedation and survival time in terminally ill cancer patients Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. Support Care Cancer 2020

Continuous deep sedation
Hospice
Palliative care
Palliative sedation
Sedative
Survival

Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. J Clin Med 2020

bilirubin
complication
liver transplantation
postoperative delirium

Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. J Clin Neurosci 2020

Cerebrovascular Disease
Pharmacology
Secondary Prevention
Smoking Cessation
Stroke
Transient Ischemic Attack (TIA)

A prospective cohort study on predictors of mortality of delirium in an emergency observational unit Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. QJM 2020

Acute confusional state
Cam-icu
Drs-r-98
Delirium
Emergency department
Intensive care unit
Mortality
Prevalence
Screening

Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. J Perianesth Nurs 2020

anxiety
coronary artery bypass
delirium
depression
postoperative

Association between fluid overload and delirium/coma in mechanically ventilated patients Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. Acute Med Surg 2020

Brain dysfunction
delirium
fluid
fluid overload
intensive care

Hallucinations after Cardiac Surgery: A Prospective Observational Study Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. Medicina (Kaunas) 2020

cardiothoracic surgery
delirium
hallucinations
neuropsychiatric outcomes

Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. J Orthop Sci 2020
Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. J Stomatol Oral Maxillofac Surg 2020

Dementia
Dentoalveolar surgery
Oral and maxillofacial surgery
Pacu
Postoperative delirium
Tooth extraction

Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function Onoda, S. Kinoshita, M. Ariyoshi, Y. J Craniofac Surg 2020
Delirium: a missing piece in the COVID-19 pandemic puzzle O'Hanlon, S. Inouye, S. K. Age Ageing 2020

Covid-19
delirium
older people

Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. Am J Geriatr Psychiatry 2020

Delirium
melatonin receptor agonist
orthopedic surgery
ramelteon

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. Alzheimers Dement 2020

biomarkers
definition
delirium
dementia
diagnosis
measurement
pathophysiology
prevention
public health campaign
treatment

Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. J Neurosurg Spine 2020

ASD = adult spinal deformity
AUC = area under the curve
BMI = body mass index
C7-CSVL = C7 plumb line to the central sacral vertical line
CCI = Charlson Comorbidity Index
CL = cervical lordosis
DVT = deep venous thrombosis
LL = lumbar lordosis
PE = pulmonary embolism
PI = pelvic incidence
PNI = prognostic nutritional index
PT = pelvic tilt
ROC = receiver operating characteristic
SSI = surgical site infection
SVA = sagittal vertical axis
TK = thoracic kyphosis
TS = T1 slope
adult spinal deformity
delirium
malnutrition
medical complications
nutritional status
prognostic nutritional index

Communication with patients in post-traumatic confusional state: perception of rehabilitation staff Nielsen, A. I. Power, E. Jensen, L. R. Brain Injury 2020

comprehension
confusion
content analysis
cross-sectional study
health personnel attitude
human
interpersonal communication
medical staff
neurorehabilitation
open-ended questionnaire
professional-patient relationship
rehabilitation center
review
traumatic brain injury
verbal communication

Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. Singapore Medical Journal 2020

dexmedetomidine
diazepam
fentanyl
haloperidol
ketamine
midazolam
morphine
propofol
anesthesia level
artificial ventilation
clinical trial
cohort analysis
controlled study
critically ill patient
delirium
endotracheal intubation
hospital discharge
hospital mortality
human
incidence
intensive care
length of stay
major clinical study
mortality
multicenter study
neurologic disease
outcome assessment
practice guideline
prospective study
public health
review
Richmond Agitation Sedation Scale
sedation
Singapore