What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Demographic and clinical characteristics of patients with delirium: analysis of a nationwide Japanese medical database
- Authors
- Ueda, N. Igarashi, M. Okuyama, K. Sano, H. Takahashi, K. P. Qureshi Z Tokita, S. Ogawa, A. Okumura, Y. Okuda, S.
- Year
- 2022
- Journal
- BMJ Open
- Abstract
OBJECTIVES: Delirium commonly occurs during hospitalisation and is associated with increased mortality, especially in elderly patients. This study aimed to determine the demographic and clinical characteristics of patients with delirium in the Japanese real-world clinical setting using a nationwide database comprising claims and discharge abstract data. DESIGN: This was an observational, cross-sectional, retrospective study in hospitalised patients with an incident delirium identified by a diagnosis based on International Classification of Diseases, 10th Revision codes or initiating antipsychotics recommended for delirium treatment in Japan during their hospitalisation. SETTING: Patients from the Medical Data Vision database including more than 400 acute care hospitals in Japan were evaluated from admission to discharge. PARTICIPANTS: Of the 32 910 227 patients who were included in the database between April 2012 and September 2020, a total of 145 219 patients met the criteria for delirium. PRIMARY AND SECONDARY OUTCOME MEASURES: Demographic and baseline characteristics, comorbidities, clinical profiles and pharmacological treatments were evaluated in patients with delirium. RESULTS: The mean (SD) patient age was 76.5 (13.8) years. More than half of the patients (n=82 159; 56.6%) were male. The most frequent comorbidities were circulatory system diseases, observed in 81 954 (56.4%) patients. Potentially inappropriate medications (PIMs) with risk of delirium including benzodiazepines and opioids were prescribed to 76 798 (52.9%) patients. Approximately three-fourths of these patients (56 949; 74.2%) were prescribed ≥4 PIMs. The most prescribed treatment for delirium was injectable haloperidol (n=82 490; 56.8%). Mean (SD) length of hospitalisation was 16.0 (12.1) days. CONCLUSIONS: The study results provide comprehensive details of the clinical characteristics of patients with delirium and treatment patterns with antipsychotics in the Japanese acute care setting. In this patient population, the prescription rate of injectable haloperidol and PIMs was high, suggesting the need for improved understanding among healthcare providers about the appropriate management of delirium, which may benefit patients.
- PMID
- Keywords
Aged
*Antipsychotic Agents/therapeutic use
Cross-Sectional Studies
*Delirium/chemically induced/drug therapy/epidemiology
Demography
Female
Haloperidol/therapeutic use
Humans
Japan/epidemiology
Male
Retrospective Studies
delirium & cognitive disorders
epidemiology
psychiatry
- Page(s)
- Volume
- Issue
| Title | Authors | Journal | Year | Keywords |
|---|---|---|---|---|
| Anxiety administrated by dexmedetomidine to prevent new-onset of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft | Zi, J. Fan, Y. Dong, C. Zhao, Y. Li, D. Tan, Q. | International Heart Journal | 2020 |
1800014314 |
| Assessment of Melatonergics in Prevention of Delirium: A Systematic Review and Meta-Analysis | Zhu, Y. Jiang, Z. Huang, H. Li, W. Ren, C. Yao, R. Wang, Y. Yao, Y. Li, W. Du, B. Xi, X. | Front Neurol | 2020 |
critical care medicine |
| Geriatric Nutritional Risk Index can predict postoperative delirium and hospital length of stay in elderly patients undergoing non-cardiac surgery | Zhao, Y. Xia, X. Xie, D. Liao, Y. Wang, Y. Chen, L. Ge, N. Yue, J. | Geriatr Gerontol Int | 2020 |
Geriatric Nutritional Risk Index |
| The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study | Zhao, Y. Ge, N. Xie, D. Gao, L. Wang, Y. Liao, Y. Yue, J. | BMC Geriatr | 2020 |
Geriatric nutritional risk index |
| Perioperative Multicomponent Interdisciplinary Program Reduces Delirium Incidence in Elderly Patients With Hip Fracture | Zhao, X. Yuan, W. | J Am Psychiatr Nurses Assoc | 2020 |
delirium |
| Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study | Zhang, Y. He, S. T. Nie, B. Li, X. Y. Wang, D. X. | J Anesth | 2020 |
Elderly |
| S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis | Zhang, X. Lyu, Y. Wang, D. | Minerva Anestesiol | 2020 | |
| Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation | Zhang, W. Wang, T. Wang, G. Yang, M. Zhou, Y. Yuan, Y. | Front Pharmacol | 2020 |
dexmedetomidine |
| Nomogram Model for Predicting Risk of Postoperative Delirium After Deep Brain Stimulation Surgery in Patients Older Than 50 Years with Parkinson Disease | Zhan, L. Wang, X. Q. Zhang, L. X. | World Neurosurg | 2020 |
Advanced age |
| Combining Ultrafast Anaesthesia and Minimal Invasive Implantation in HeartMate 3: A Pilot Study | Zayat, R. Ahmad, U. Twarie, L. Moza, A. Schaelte, G. Allham, O. Haneya, A. Khattab, M. Schnoering, H. Autschbach, R. | The Journal of heart and lung transplantation | 2020 |
adult |
| Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients | Yuan, Y. Li, Z. Yang, N. Han, Y. Ji, X. Han, D. Wang, X. Li, Y. Liu, T. Yuan, F. He, J. Liu, Y. Ni, C. Zou, P. Wang, G. Guo, X. Zhou, Y. | Front Aging Neurosci | 2020 |
exosome |
| A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care | Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K. | Age Ageing | 2020 |
delirium |
| Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery | Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P. | American Journal of Medicine | 2020 |
adult |
| Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients | Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H. | World Neurosurgery | 2020 |
titanium cage |
| Risk factors for delirium in intensive care unit and its duration | Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
| Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials | Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P. | Sleep Med Rev | 2020 |
Delirium |
| Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial | Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L. | Medicine (United States) | 2020 |
ChiCTR-INR-16009116 |
| Delirium screening practice in specialist palliative care units: a survey | Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J. | BMJ Support Palliat Care | 2020 |
delirium |
| Movements and trends in intensive care pain treatment and sedation: What matters to the patient? | Wøien, H. | J Clin Nurs | 2020 |
Adult |
| Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications | Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J. | Am J Surg | 2020 |
Antipsychotic Agents/ adverse effects |
| Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery | Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. | Acta Anaesthesiol Scand | 2020 | |
| The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. | Palliat Med | 2020 |
Delirium |
| Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? | Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm | J Clin Nurs | 2020 |
Aged |
| Predicting postoperative delirium after microvascular decompression surgery with machine learning | Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. | J Clin Anesth | 2020 |
Machine learning |
| Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System | Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. | Statistics in Medicine | 2020 |
amfebutamone |
| Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery | Wang, L. Zhang, T. Huang, L. Peng, W. | Biomed Res Int | 2020 | |
| Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial | Wang, L. Huang, L. Zhang, T. Peng, W. | Biomed Res Int | 2020 | |
| Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study | Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. | J Affect Disord | 2020 |
Cognition |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
| Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience | Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. | Gastroenterology Report | 2020 |
politef implant |
| Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study | Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. | Eur J Intern Med | 2020 |
Anticholinergics |
| Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome | von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. | Neurocrit Care | 2020 |
Cam-icu |
| Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism | Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. | Pharmacotherapy | 2020 |
critical care |
| Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study | Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
| New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study | Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. | Dement Geriatr Cogn Disord | 2020 |
Delirium |
| A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) | Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. | J Am Geriatr Soc | 2020 | |
| Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital | Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. | Age Ageing | 2020 |
acute |
| Registration of attentional function as a predictor of incident delirium (the RAPID study) | van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. | Alzheimers Dement (N Y) | 2020 |
attentional function |
| Predisposition for delirium and EEG characteristics | van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. | Clin Neurophysiol | 2020 |
Delirium |
| Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation | van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. | Journal of Thoracic and Cardiovascular Surgery | 2020 |
aged |
| Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial | Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. | Injury | 2020 |
aged |
| Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age | Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. | Heart Surg Forum | 2020 | |
| Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography | Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. | Intensive Care Medicine | 2020 |
adult |
| Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium | Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. | J Crit Care | 2020 |
Delirium |
| The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial | Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. | Geriatr Orthop Surg Rehabil | 2020 |
acute pain medicine |
| The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study | Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. | J Cardiothorac Vasc Anesth | 2020 |
Mild cognitive impairment |
| Development of a Palliative Care Toolkit for the COVID-19 Pandemic | Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. | Journal of pain and symptom management | 2020 |
adult |
| Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis | Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. | J Am Med Dir Assoc | 2020 |
Aging |
| Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study | Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. | Saudi Journal of Anaesthesia | 2020 |
laryngeal mask |
| Atypical presentation of COVID-19 in a frail older person | Tay, H. S. Harwood, R. | Age Ageing | 2020 |
Covid-19 |
| ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery | Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M. | Anesth Analg | 2020 | |
| Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery | Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X. | Biosci Rep | 2020 |
Dexmedetomidine |
| Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity | Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. | Br J Anaesth | 2020 |
cognitive dysfunction |
| Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients | Tan, C. Saito, N. Miyawaki, I. Shiotani, H. | Chronobiol Int | 2020 |
Postoperative delirium |
| Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan | Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. | Current Medical Research and Opinion | 2020 |
hypnotic agent |
| Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis | Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. | Anesth Analg | 2020 | |
| Risk and Consequences of Postoperative Delirium in Cardiac Surgery | Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. | Thorac Cardiovasc Surg | 2020 | |
| Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study | Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2020 |
Hip fracture |
| Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study | Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. | JACCP Journal of the American College of Clinical Pharmacy | 2020 |
adult |
| Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review | Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. | J Clin Nurs | 2020 |
In-hospital fall |
| Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care | Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. | Crit Care Nurse | 2020 | |
| Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) | Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. | Pediatr Crit Care Med | 2020 | |
| Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial | Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. | Br J Anaesth | 2020 |
awareness |
| Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital | Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. | Minerva Anestesiol | 2020 | |
| Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis | Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. | Medicine (Baltimore) | 2020 |
Apache |
| Validation of a multidisciplinary care protocol for critically ill patients with delirium | Souza, T. L. Azzolin, K. O. Souza, E. N. | Revista gaucha de enfermagem | 2020 |
adult |
| Hospital Costs and Reimbursement Model for a Geriatric Emergency Department | Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. | Acad Emerg Med | 2020 | |
| Natural light exposure and delirium in ICU: does the dark side cloud everything? | Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. | Annals of Intensive Care | 2020 |
sedative agent |
| Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review | Soleman, J. Guzman, R. | Behavioural Neurology | 2020 |
rigid endoscope |
| Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial | Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J. | Age Ageing | 2020 |
delirium prevention |
| Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation | Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M. | Int J Artif Organs | 2020 |
Extracorporeal membrane oxygenation |
| Are Antipsychotics Helpful for Preventing or Treating Delirium? | Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M. | J Gerontol Nurs | 2020 | |
| Family caregiver's experience of caring for an older adult with delirium: A systematic review | Shrestha, P. Fick, D. M. | Int J Older People Nurs | 2020 |
delirium |
| Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis | Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z. | Clin Exp Pharmacol Physiol | 2020 |
dexmedetomidine |
| Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery | Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z. | J Int Med Res | 2020 |
Postoperative delirium |
| Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation | Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S. | J Am Geriatr Soc | 2020 |
dementia |
| Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain" | Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L. | Anesth Analg | 2020 | |
| Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation | Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M. | Catheter Cardiovasc Interv | 2020 |
Nirs |
| Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration | Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A. | Pediatric Dental Journal | 2020 |
propofol |
| Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis | Segers, K. Benoit, F. Meyts, J. M. Surquin, M. | Psychogeriatrics | 2020 |
Alzheimerʼs disease |
| Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU | Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R. | Crit Care Explor | 2020 |
benzodiazepines |
| Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study | Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. | Crit Care Explor | 2020 |
benzodiazepine |
| Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database | Sato, K. Mano, T. Iwata, A. Toda, T. | Biosci Trends | 2020 |
Adverse Drug Reaction Reporting Systems |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
| Non-pharmacological approaches in the prevention of delirium | Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. | European Geriatric Medicine | 2020 |
psychotropic agent |
| Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study | Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. | Medicina (Kaunas) | 2020 |
biomarker |
| Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
| Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta | Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. | Egypt Heart J | 2020 |
Aging |
| Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients | Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. | J Psychiatr Res | 2020 |
Aging |
| Major surgery induces acute changes in measured DNA methylation associated with immune response pathways | Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. | Sci Rep | 2020 | |
| Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period | Rostoft, S. Hamaker, M. E. | Eur J Surg Oncol | 2020 |
Cognition |
| The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review | Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. | Age Ageing | 2020 |
delirium |
| Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review | Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. | Crit Care Med | 2020 | |
| Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal | Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. | Minerva Anestesiol | 2020 | |
| Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic | Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. | Lancet Psychiatry | 2020 |
Coronavirus Infections/ complications |
| Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Acta Neuropsychiatr | 2020 |
anti-N-methyl-D-aspartate receptor encephalitis |
| Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Gen Hosp Psychiatry | 2020 |
Anti-NMDA receptor encephalitis |
| Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit | Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |