What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Scheduled Prophylactic 6-Hourly IV AcetaminopheN to Prevent Postoperative Delirium in Older CaRdiac SurgicAl Patients (PANDORA): protocol for a multicentre randomised controlled trial
- Authors
- Khera, T. Mathur, P. A. Banner-Goodspeed, V. M. Narayanan, S. McGourty, M. Kelly, L. Palihnich, K. Novack, L. Davis, R. Talmor, D. Marcantonio, E. R. Subramaniam, B.
- Year
- 2021
- Journal
- BMJ Open
- Abstract
INTRODUCTION: Postoperative delirium is common among older cardiac surgery patients. Often difficult to predict and address prophylactically, delirium complicates the postoperative course by increasing morbidity and mortality as well as prolonging both hospital and intensive care unit (ICU) lengths of stay. Based on our pilot trial, we intend to study the effect of scheduled 6-hourly acetaminophen administration for 48 hours post-cardiac surgery with cardiopulmonary bypass (CPB) on the incidence of in-hospital delirium and long-term neurocognitive outcomes. Additionally, effect on duration and severity of delirium, rescue analgesic consumption, acute and chronic pain scores and lengths of hospital and ICU stay will also be explored. METHODS AND ANALYSIS: This multicentre, randomised, placebo-controlled, quadruple-blinded trial will include 900 older (>60 years) cardiac surgical patients requiring CPB. Patients meeting the inclusion criteria and not meeting any exclusion criteria will be enrolled at seven centres across the USA with Beth Israel Deaconess Medical Center (BIDMC), Boston, as the central coordinating centre. Additional sites may be included to broaden or speed accrual. The primary outcome measure is the incidence of in-hospital delirium till day 30. Secondary outcomes include the duration and severity of in-hospital delirium, hospital and ICU lengths of stay, postoperative pain scores, postoperative rescue analgesic consumption, postoperative cognitive function and chronic sternal pain. Creation of a biorepository and the use of intraoperative-blinded electroencephalogram (EEG) and cerebral oximetry data will support exploratory endpoints to determine mechanistic predictors of postoperative delirium. ETHICS AND DISSEMINATION: This trial is approved and centrally facilitated by the Institutional Review Board at BIDMC. An independent Data Safety and Monitoring Board is responsible for maintaining safety oversight. Protocol # 2019 P00075, V.1.4 (dated 20 October 2020). TRIAL REGISTRATION NUMBER: NCT04093219.
- PMID
- Keywords
Acetaminophen
Aged
Boston
Cardiac Surgical Procedures/adverse effects
Cerebrovascular Circulation
Delirium/prevention & control
Double-Blind Method
Humans
Multicenter Studies as Topic
Oximetry
Randomized Controlled Trials as Topic
adult intensive & critical care
anaesthesia in cardiology
cardiac surgery
delirium & cognitive disorders
- Page(s)
- Volume
- 11
- Issue
- 3
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery | Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. | Acta Anaesthesiol Scand | 2020 | |
The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study | Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. | Palliat Med | 2020 |
Delirium |
Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? | Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm | J Clin Nurs | 2020 |
Aged |
Predicting postoperative delirium after microvascular decompression surgery with machine learning | Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. | J Clin Anesth | 2020 |
Machine learning |
Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System | Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. | Statistics in Medicine | 2020 |
amfebutamone |
Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery | Wang, L. Zhang, T. Huang, L. Peng, W. | Biomed Res Int | 2020 | |
Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial | Wang, L. Huang, L. Zhang, T. Peng, W. | Biomed Res Int | 2020 | |
Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study | Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. | J Affect Disord | 2020 |
Cognition |
Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
Development and validation of the delirium risk assessment score (DRAS) | Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. | Eur Geriatr Med | 2020 |
Delirium |
Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience | Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. | Gastroenterology Report | 2020 |
politef implant |
Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study | Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. | Eur J Intern Med | 2020 |
Anticholinergics |
Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome | von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. | Neurocrit Care | 2020 |
Cam-icu |
Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism | Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. | Pharmacotherapy | 2020 |
critical care |
Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study | Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. | Journal of Cardiothoracic and Vascular Anesthesia | 2020 |
adult |
New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study | Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. | Dement Geriatr Cogn Disord | 2020 |
Delirium |
A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) | Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. | J Am Geriatr Soc | 2020 | |
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital | Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. | Age Ageing | 2020 |
acute |
Registration of attentional function as a predictor of incident delirium (the RAPID study) | van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. | Alzheimers Dement (N Y) | 2020 |
attentional function |
Predisposition for delirium and EEG characteristics | van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. | Clin Neurophysiol | 2020 |
Delirium |
Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation | van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. | Journal of Thoracic and Cardiovascular Surgery | 2020 |
aged |
Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial | Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. | Injury | 2020 |
aged |
Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age | Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. | Heart Surg Forum | 2020 | |
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography | Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. | Intensive Care Medicine | 2020 |
adult |
Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium | Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. | J Crit Care | 2020 |
Delirium |
The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial | Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. | Geriatr Orthop Surg Rehabil | 2020 |
acute pain medicine |
The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study | Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. | J Cardiothorac Vasc Anesth | 2020 |
Mild cognitive impairment |
Development of a Palliative Care Toolkit for the COVID-19 Pandemic | Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. | Journal of pain and symptom management | 2020 |
adult |
Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis | Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. | J Am Med Dir Assoc | 2020 |
Aging |
Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study | Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. | Saudi Journal of Anaesthesia | 2020 |
laryngeal mask |
Atypical presentation of COVID-19 in a frail older person | Tay, H. S. Harwood, R. | Age Ageing | 2020 |
Covid-19 |
ADAPT-2: A Randomized Clinical Trial to Reduce Intraoperative EEG Suppression in Older Surgical Patients Undergoing Major Noncardiac Surgery | Tang, C. J. Jin, Z. Sands, L. P. Pleasants, D. Tabatabai, S. Hong, Y. Leung, J. M. | Anesth Analg | 2020 | |
Dexmedetomidine with sufentanil in intravenous patient-controlled analgesia for relief from postoperative pain, inflammation and delirium after esophageal cancer surgery | Tang, C. Hu, Y. Zhang, Z. Wei, Z. Wang, H. Geng, Q. Shi, S. Wang, S. Wang, J. Chai, X. | Biosci Rep | 2020 |
Dexmedetomidine |
Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity | Tanabe, S. Mohanty, R. Lindroth, H. Casey, C. Ballweg, T. Farahbakhsh, Z. Krause, B. Prabhakaran, V. Banks, M. I. Sanders, R. D. | Br J Anaesth | 2020 |
cognitive dysfunction |
Preoperative circadian physical activity rhythm and postoperative delirium in cardiovascular surgery patients | Tan, C. Saito, N. Miyawaki, I. Shiotani, H. | Chronobiol Int | 2020 |
Postoperative delirium |
Real-world evidence of the safety and efficacy profile of suvorexant in elderly patients with insomnia: a sub-analysis of the post-marketing drug-use results survey in Japan | Takeuchi, Y. Sano, H. Asai, Y. Miyazaki, M. Iwakura, M. Maeda, Y. | Current Medical Research and Opinion | 2020 |
hypnotic agent |
Electroencephalography-Guided Anesthetic Delivery for Preventing Postoperative Delirium in Adults: An Updated Meta-analysis | Sun, Y. Ye, F. Wang, J. Ai, P. Wei, C. Wu, A. Xie, W. | Anesth Analg | 2020 | |
Risk and Consequences of Postoperative Delirium in Cardiac Surgery | Sugimura, Y. Sipahi, N. F. Mehdiani, A. Petrov, G. Awe, M. Minol, J. P. Boeken, U. Korbmacher, B. Lichtenberg, A. Dalyanoglu, H. | Thorac Cardiovasc Surg | 2020 | |
Risk of Hospitalized Falls and Hip Fractures in 22,103 Older Adults Receiving Mental Health Care vs 161,603 Controls: A Large Cohort Study | Stubbs, B. Perara, G. Koyanagi, A. Veronese, N. Vancampfort, D. Firth, J. Sheehan, K. De Hert, M. Stewart, R. Mueller, C. | J Am Med Dir Assoc | 2020 |
Hip fracture |
Pharmacist-driven discontinuation of antipsychotics for ICU delirium: A quasi-experimental study | Stuart, M. M. Smith, Z. R. Payter, K. A. Martz, C. R. To, L. Swiderek, J. L. Coba, V. E. Peters, M. A. | JACCP Journal of the American College of Clinical Pharmacy | 2020 |
adult |
Interventions to prevent in-hospital falls in older people with cognitive impairment for further research: a mixed studies review | Stockwell-Smith, G. Adeleye, A. Chaboyer, W. Cooke, M. Phelan, M. Todd, J. A. Grealish, L. | J Clin Nurs | 2020 |
In-hospital fall |
Early Identification of Delirium in Intensive Care Unit Patients: Improving the Quality of Care | Spiegelberg, J. Song, H. Pun, B. Webb, P. Boehm, L. M. | Crit Care Nurse | 2020 | |
Efficacy and Safety of Dexmedetomidine for Prolonged Sedation in the PICU: A Prospective Multicenter Study (PROSDEX) | Sperotto, F. Mondardini, M. C. Dell'Oste, C. Vitale, F. Ferrario, S. Lapi, M. Ferrero, F. Dusio, M. P. Rossetti, E. Daverio, M. Amigoni, A. | Pediatr Crit Care Med | 2020 | |
Restricted versus liberal intraoperative benzodiazepine use in cardiac anaesthesia for reducing delirium (B-Free Pilot): a pilot, multicentre, randomised, cluster crossover trial | Spence, J. Belley-Côté, E. Jacobsohn, E. Lee, S. F. Whitlock, R. Bangdiwala, S. Syed, S. Sarkaria, A. MacIsaac, S. Lengyel, A. Long, S. Um, K. McIntyre, W. F. Kavosh, M. Fast, I. Arora, R. Lamy, A. Connolly, S. Devereaux, P. J. | Br J Anaesth | 2020 |
awareness |
Thoracic continuous spinal anesthesia for high-risk comorbid older patients undergoing major abdominal surgery: one-year experience of an Italian geriatric hospital | Spannella, F. Giulietti, F. Damiani, E. Faloia, L. Stronati, M. Venezia, A. Vincenzi, P. Castellani, D. Boccoli, G. Dellabella, M. Giampieri, M. Sarzani, R. Starnari, R. | Minerva Anestesiol | 2020 | |
Identification of distinct clinical phenotypes in mechanically ventilated patients with acute brain dysfunction using cluster analysis | Souza-Dantas, V. C. Dal-Pizzol, F. Tomasi, C. D. Spector, N. Soares, M. Bozza, F. A. Póvoa, P. Salluh, J. I. F. | Medicine (Baltimore) | 2020 |
Apache |
Validation of a multidisciplinary care protocol for critically ill patients with delirium | Souza, T. L. Azzolin, K. O. Souza, E. N. | Revista gaucha de enfermagem | 2020 |
adult |
Hospital Costs and Reimbursement Model for a Geriatric Emergency Department | Southerland, L. T. Savage, E. L. Muska Duff, K. Caterino, J. M. Bergados, T. R. Hunold, K. M. Finnegan, G. I. Archual, G. | Acad Emerg Med | 2020 | |
Natural light exposure and delirium in ICU: does the dark side cloud everything? | Sonneville, R. Smonig, R. Dupuis, C. Bouadma, L. de Montmollin, E. Timsit, J. F. | Annals of Intensive Care | 2020 |
sedative agent |
Neurocognitive Complications after Ventricular Neuroendoscopy: A Systematic Review | Soleman, J. Guzman, R. | Behavioural Neurology | 2020 |
rigid endoscope |
Investigation of ward fidelity to a multicomponent delirium prevention intervention during a multicentre, pragmatic, cluster randomised, controlled feasibility trial | Smith, J. Green, J. Siddiqi, N. Inouye, S. K. Collinson, M. Farrin, A. Young, J. | Age Ageing | 2020 |
delirium prevention |
Clinical outcomes associated with sedation and analgesia in patients supported with venoarterial extracorporeal membrane oxygenation | Skelton, P. A. Lillyblad, M. P. Eckman, P. M. Samara, M. A. Williams, D. M. Wilson, K. J. Stanberry, L. I. Hryniewicz, K. M. | Int J Artif Organs | 2020 |
Extracorporeal membrane oxygenation |
Are Antipsychotics Helpful for Preventing or Treating Delirium? | Singu, S. Koneru, M. Robinson, K. A. Neufeld, K. J. Oh, E. S. Wilson, L. M. Needham, D. M. Balagani, A. Aldabain, L. Nikooie, R. Fick, D. M. | J Gerontol Nurs | 2020 | |
Family caregiver's experience of caring for an older adult with delirium: A systematic review | Shrestha, P. Fick, D. M. | Int J Older People Nurs | 2020 |
delirium |
Dexmedetomidine in the prevention of postoperative delirium in elderly patients following non-cardiac surgery: A systematic review and meta-analysis | Shen, Q. H. Li, H. F. Zhou, X. Y. Yuan, X. Z. | Clin Exp Pharmacol Physiol | 2020 |
dexmedetomidine |
Relation of serum melatonin levels to postoperative delirium in older patients undergoing major abdominal surgery | Shen, Q. H. Li, H. F. Zhou, X. Y. Lu, Y. P. Yuan, X. Z. | J Int Med Res | 2020 |
Postoperative delirium |
Characteristics and Outcomes of Dementia Patients Who Receive Inpatient Palliative Care Consultation | Sharda, N. Zietlow, K. Wong, S. Kuchibhatla, M. Johnson, K. S. | J Am Geriatr Soc | 2020 |
dementia |
Low Frontal Alpha Power Is Associated With the Propensity for Burst Suppression: An Electroencephalogram Phenotype for a "Vulnerable Brain" | Shao, Y. R. Kahali, P. Houle, T. T. Deng, H. Colvin, C. Dickerson, B. C. Brown, E. N. Purdon, P. L. | Anesth Analg | 2020 | |
Dynamics of cerebral oxygenation during rapid ventricular pacing and its impact on outcome in transfemoral transcatheter aortic valve implantation | Seppelt, P. C. Mas-Peiro, S. De Rosa, R. Murray, I. M. Arsalan, M. Holzer, L. Lotz, G. Meybohm, P. Zacharowski, K. Walther, T. Zeiher, A. M. Fichtlscherer, S. Vasa-Nicotera, M. | Catheter Cardiovasc Interv | 2020 |
Nirs |
Haemodynamic changes and emergence delirium in children undergoing isoflurane general anaesthesia for dental treatments: effect of propofol administration | Selvi-Kuvvetli, S. Turan, B. S. Bayrak, G. D. Noyan, A. | Pediatric Dental Journal | 2020 |
propofol |
Anxiety symptoms are quantitatively and qualitatively different in dementia with Lewy bodies than in Alzheimer's disease in the years preceding clinical diagnosis | Segers, K. Benoit, F. Meyts, J. M. Surquin, M. | Psychogeriatrics | 2020 |
Alzheimerʼs disease |
Evaluation of Sedation Outcomes Following Increased Dexmedetomidine Use in the ICU | Schuler, B. R. Kovacevic, M. P. Dube, K. M. Szumita, P. M. DeGrado, J. R. | Crit Care Explor | 2020 |
benzodiazepines |
Effect of Flumazenil on Hypoactive Delirium in the ICU: A Double-Blind, Placebo-Controlled Pilot Study | Schomer, K. J. Duby, J. J. Firestone, R. L. Louie, E. L. Sebat, C. M. Love, D. M. Cocanour, C. S. Albertson, T. E. | Crit Care Explor | 2020 |
benzodiazepine |
Neuropsychiatric adverse events of chloroquine: a real-world pharmacovigilance study using the FDA Adverse Event Reporting System (FAERS) database | Sato, K. Mano, T. Iwata, A. Toda, T. | Biosci Trends | 2020 |
Adverse Drug Reaction Reporting Systems |
Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
Prospective Study of Factors Associated With Postoperative Delirium After Urgent Abdominal Surgery | Sánchez Acedo, P. Eguaras Córdoba, I. Zazpe Ripa, C. Herrera Cabezón, J. Tarifa Castilla, A. | Cir Esp | 2020 |
Ancianos |
Non-pharmacological approaches in the prevention of delirium | Salvi, F. Young, J. Lucarelli, M. Aquilano, A. Luzi, R. Dell’Aquila, G. Cherubini, A. | European Geriatric Medicine | 2020 |
psychotropic agent |
Natriuretic Peptides as a Prognostic Marker for Delirium in Cardiac Surgery-A Pilot Study | Saller, T. Peterss, S. Scheiermann, P. Eser-Valeri, D. Ehler, J. Bruegger, D. Chappell, D. Kofler, O. Hagl, C. Hofmann-Kiefer, K. | Medicina (Kaunas) | 2020 |
biomarker |
Prospective Evaluation of Delirium in Geriatric Patients Undergoing Emergency General Surgery | Saljuqi, A. T. Hanna, K. Asmar, S. Tang, A. Zeeshan, M. Gries, L. Ditillo, M. Kulvatunyou, N. Castanon, L. Joseph, B. | J Am Coll Surg | 2020 | |
Effect of moderate hypothermic circulatory arrest on neurological outcomes in elderly patients undergoing replacement of the thoracic aorta | Salem, M. Friedrich, C. Thiem, A. Salem, M. A. Puehler, T. Rusch, R. Berndt, R. Cremer, J. Haneya, A. | Egypt Heart J | 2020 |
Aging |
Epigenetics of neuroinflammation: Immune response, inflammatory response and cholinergic synaptic involvement evidenced by genome-wide DNA methylation analysis of delirious inpatients | Saito, T. Toda, H. Duncan, G. N. Jellison, S. S. Yu, T. Klisares, M. J. Daniel, S. Andreasen, A. J. Leyden, L. R. Hellman, M. M. Shinozaki, E. Lee, S. Yoshino, A. Cho, H. R. Shinozaki, G. | J Psychiatr Res | 2020 |
Aging |
Major surgery induces acute changes in measured DNA methylation associated with immune response pathways | Sadahiro, R. Knight, B. James, F. Hannon, E. Charity, J. Daniels, I. R. Burrage, J. Knox, O. Crawford, B. Smart, N. J. Mill, J. | Sci Rep | 2020 | |
Basic geriatric principles for colorectal surgeons: How to optimize assessment and care of older patients in the perioperative period | Rostoft, S. Hamaker, M. E. | Eur J Surg Oncol | 2020 |
Cognition |
The association of delirium severity with patient and health system outcomes in hospitalised patients: a systematic review | Rosgen, B. K. Krewulak, K. D. Stelfox, H. T. Ely, E. W. Davidson, J. E. Fiest, K. M. | Age Ageing | 2020 |
delirium |
Reporting of Outcomes and Outcome Measures in Studies of Interventions to Prevent and/or Treat Delirium in the Critically Ill: A Systematic Review | Rose, L. Agar, M. Burry, L. Campbell, N. Clarke, M. Lee, J. Marshall, J. Siddiqi, N. Page, V. | Crit Care Med | 2020 | |
Abdominal aortic aneurysm patients remain at risk for delirium on the surgical ward after intensive care unit dismissal | Roijers, J. P. Spillenaar Bilgen, R. Hopmans, C. J. Mulder, P. G. Buimer, M. G. Ho, G. H. de Groot, H. G. Veen, E. J. Besselink-Lobanova, A. van der Meer, N. J. van der Laan, L. | Minerva Anestesiol | 2020 | |
Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID-19 pandemic | Rogers, J. P. Chesney, E. Oliver, D. Pollak, T. A. McGuire, P. Fusar-Poli, P. Zandi, M. S. Lewis, G. David, A. S. | Lancet Psychiatry | 2020 |
Coronavirus Infections/ complications |
Characterisation and outcome of neuropsychiatric symptoms in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Acta Neuropsychiatr | 2020 |
anti-N-methyl-D-aspartate receptor encephalitis |
Delirious mania as a frequent and recognizable neuropsychiatric syndrome in patients with anti-NMDAR encephalitis | Restrepo-Martinez, M. Ramirez-Bermudez, J. Bayliss, L. Espinola-Nadurille, M. | Gen Hosp Psychiatry | 2020 |
Anti-NMDA receptor encephalitis |
Diffusion tensor imaging and resting-state functional magnetic resonance imaging in patients with delirium in intensive care unit | Renjie, S. Ganjun, S. Peng, X. Haizhen, D. Tianxi, Z. Yuanlan, L. Mo, L. Xiaoyun, F. | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | 2020 |
sedative agent |
Mortality of gerontopsychiatric inpatients in Graz, Austria—a retrospective case-control study | Rásky, É Stolz, E. Jagsch, C. | Neuropsychiatrie | 2020 |
article |
Barriers to rehabilitation after critical illness: a survey of multidisciplinary healthcare professionals caring for ICU survivors in an acute care hospital | Rai, S. Anthony, L. Needham, D. M. Georgousopoulou, E. N. Sudheer, B. Brown, R. Mitchell, I. van Haren, F. | Aust Crit Care | 2020 |
Intensive care |
Older Patients with Alzheimer's Disease-Related Cortical Atrophy Who Develop Post-Operative Delirium May Be at Increased Risk of Long-Term Cognitive Decline after Surgery | Racine, A. M. Touroutoglou, A. Abrantes, T. Wong, B. Fong, T. G. Cavallari, M. Travison, T. G. Gou, Y. Marcantonio, E. R. Alsop, D. C. Jones, R. N. Inouye, S. K. Dickerson, B. C. | Journal of Alzheimer's Disease | 2020 |
aged |
Psychiatric comorbidities in cancer patients: acute interventions by the psychiatric consultation liaison service | Quante, A. Schulz, K. Fissler, M. | Wiener Medizinische Wochenschrift | 2020 |
adult |
Delirium is associated with higher mortality in transcatheter aortic valve replacement: systemic review and meta-analysis | Prasitlumkum, N. Mekritthikrai, R. Kewcharoen, J. Kanitsoraphan, C. Mao, M. A. Cheungpasitporn, W. | Cardiovasc Interv Ther | 2020 |
Delirium |
A novel geriatric assessment tool that predicts postoperative complications in older adults with cancer | Pollock, Y. Chan, C. L. Hall, K. Englesbe, M. Diehl, K. M. Min, L. | J Geriatr Oncol | 2020 |
Functional decline |
Modifiable factors associated with postoperative delirium after hip fracture repair: An age-stratified retrospective cohort study | Poeran, J. Cozowicz, C. Zubizarreta, N. Weinstein, S. M. Deiner, S. G. Leipzig, R. M. Friedman, J. I. Liu, J. Mazumdar, M. Memtsoudis, S. G. | Eur J Anaesthesiol | 2020 | |
Downregulation of synapse-associated protein expression and loss of homeostatic microglial control in cerebrospinal fluid of infectious patients with delirium and patients with Alzheimer's disease | Peters van Ton, A. M. Verbeek, M. M. Alkema, W. Pickkers, P. Abdo, W. F. | Brain Behav Immun | 2020 |
Alzheimer’s disease |
Documentation of acute change in mental status in nursing homes highlights opportunity to augment infection surveillance criteria | Penna, A. R. Sancken, C. L. Stone, N. D. Eure, T. R. Bamberg, W. Barney, G. Barter, D. Carswell, S. Clogher, P. Dumyati, G. Felsen, C. B. Frank, L. Godine, D. Johnston, H. Kainer, M. A. Li, L. Lynfield, R. Mahoehney, J. P. Nadle, J. Pierce, R. Ray, S. M. | Infect Control Hosp Epidemiol | 2020 | |
Effect of Dexmedetomidine on Cardiac Surgery-Associated Acute Kidney Injury: A Meta-Analysis With Trial Sequential Analysis of Randomized Controlled Trials | Peng, K. Li, D. Applegate, R. L., 2nd Lubarsky, D. A. Ji, F. H. Liu, H. | J Cardiothorac Vasc Anesth | 2020 |
acute kidney injury |
Electroencephalogram Burst-suppression during Cardiopulmonary Bypass in Elderly Patients Mediates Postoperative Delirium | Pedemonte, J. C. Plummer, G. S. Chamadia, S. Locascio, J. J. Hahm, E. Ethridge, B. Gitlin, J. Ibala, R. Mekonnen, J. Colon, K. M. Westover, M. B. D'Alessandro, D. A. Tolis, G. Houle, T. Shelton, K. T. Qu, J. Akeju, O. | Anesthesiology | 2020 | |
Evaluating delirium outcomes among older adults in the surgical intensive care unit | Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. | Heart Lung | 2020 |
Critical care |
Association between continuous deep sedation and survival time in terminally ill cancer patients | Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. | Support Care Cancer | 2020 |
Continuous deep sedation |
Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study | Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. | J Clin Med | 2020 |
bilirubin |
Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review | Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. | J Clin Neurosci | 2020 |
Cerebrovascular Disease |
A prospective cohort study on predictors of mortality of delirium in an emergency observational unit | Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. | QJM | 2020 |
Acute confusional state |
Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery | Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. | J Perianesth Nurs | 2020 |
anxiety |
Association between fluid overload and delirium/coma in mechanically ventilated patients | Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. | Acute Med Surg | 2020 |
Brain dysfunction |
Hallucinations after Cardiac Surgery: A Prospective Observational Study | Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. | Medicina (Kaunas) | 2020 |
cardiothoracic surgery |
Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes | Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. | J Orthop Sci | 2020 |