Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Delirium in nursing home residents: is there a role of antidepressants? A cross sectional study
Authors
Fedecostante, M. Balietti, P. Di Santo, S. G. Zambon, A. Marengoni, A. Morandi, A. Beccacece, A. Bellelli, G. Cherubini, A.
Year
2024
Journal
BMC Geriatr
Abstract

BACKGROUND: Delirium is strongly associated with poor health outcomes, yet it is frequently underdiagnosed. Limited research on delirium has been conducted in Nursing Homes (NHs). Our aim is to assess delirium prevalence and its associated factors, in particular pharmacological prescription, in this care setting. METHODS: Data from the Italian “Delirium Day” 2016 Edition, a national multicenter point-prevalence study on patients aged 65 and older were analyzed to examine the associations between the prevalence of delirium and its subtypes with demographics and information about medical history and pharmacological treatment. Delirium was assessed using the Assessment test for delirium and cognitive impairment (4AT). Motor subtype was evaluated using the Delirium Motor Subtype Scale (DMSS). RESULTS: 955 residents, from 32 Italian NHs with a mean age of 84.72 ± 7.78 years were included. According to the 4AT, delirium was present in 260 (27.2%) NHs residents, mainly hyperactive (35.4%) or mixed subtypes (20.7%). Antidepressant treatment with selective serotonin reuptake inhibitors (SSRIs) was associated with lower delirium prevalence in univariate and multivariate analyses. CONCLUSIONS: The high prevalence of delirium in NHs highlights the need to systematically assess its occurrence in this care settings. The inverse association between SSRIs and delirium might imply a possible preventive role of this class of therapeutic agents against delirium in NHs, yet further studies are warranted to ascertain any causal relationship between SSRIs intake and reduced delirium incidence.

PMID

PMID: 39289644

PMCID: PMC11409737

Keywords

Humans
*Nursing Homes/trends
Male
Cross-Sectional Studies
Female
Aged, 80 and over
*Delirium/epidemiology/diagnosis
Aged
Italy/epidemiology
*Antidepressive Agents/therapeutic use
Prevalence
Selective Serotonin Reuptake Inhibitors/therapeutic use/adverse effects
Homes for the Aged
4at
Antidepressants
Delirium
Delirium subtypes
Nursing home
SSRIs

Page(s)
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Perioperative Multidisciplinary Delirium Prevention: A Longitudinal Case Report Hamlet, K. M. Pasternak, E. Rabai, F. Mufti, M. Hernaiz Alonso, C. Price, C. C. A A Pract 2021
Cerebrospinal Fluid Concentration of Neurogranin in Hip Fracture Patients with Delirium Halaas, N. B. Zetterberg, H. Idland, A. V. Knapskog, A. B. Watne, L. O. Blennow, K. J Alzheimers Dis 2021

Alzheimer’s disease
biomarkers
cerebrospinal fluid proteins
delirium
neurotransmitter agents

A retrospective study of factors associated with persistent delirium Goto, H. Yamauchi, T. Okumura, K. Matsuoka, K. Toritsuka, M. Yasuno, F. Uemura, H. Kuki, K. Makinodan, M. Kishimoto, T. Psychogeriatrics 2021

Case-Control Studies
Delirium/diagnosis/epidemiology
Hospitals, General
Humans
Male
Pain
Retrospective Studies
Risk Factors
analgesic
case-control study
delirium
general hospital
persistent delirium

Association Between Early Tracheostomy and Delirium in Older Adults in the United States Gazda, A. J. Kwak, M. J. Jani, P. Dinh, K. Hussain, R. Dronavalli, G. Warner, M. Salas De Armas, I. Kumar, S. Nathan, S. Kar, B. Gregoric, I. D. Patel, B. Akkanti, B. J Cardiothorac Vasc Anesth 2021

delirium
intensive care unit
mechanical ventilation
prevention of ICU delirium
tracheostomy

Poor outcomes of delirium in the intensive care units are amplified by increasing age: A retrospective cohort study Gao, W. Zhang, Y. P. Jin, J. F. World J Emerg Med 2021

Aging
Delirium
Intensive care
Mortality

Postoperative Delirium is Associated With Prolonged Head and Neck Resection and Reconstruction Surgery: An Institutional Study Edwards, D. A. Medhavy, A. Hoffman, O. G. Hoffman, G. R. J Oral Maxillofac Surg 2021

Aged
Delirium/epidemiology/etiology
Female
Humans
Male
Postoperative Complications/epidemiology/etiology
Reconstructive Surgical Procedures
Retrospective Studies
Risk Factors

Delirium Assessment in Critically Ill Older Adults: Considerations During the COVID-19 Pandemic Duggan, M. C. Van, J. Ely, E. W. Crit Care Clin 2021

Aged
Aged, 80 and over
Betacoronavirus
Covid-19
Coronavirus Infections/ complications
Delirium/ complications/ diagnosis/prevention & control
Dementia/ complications
Hearing Loss/complications
Humans
Intensive Care Units
Pandemics
Patient Care Team
Pneumonia, Viral/ complications
SARS-CoV-2
Vision Disorders/complications
Assessment
Critical care
Delirium
Geriatrics
Intensive care unit
Older adults
Pandemic
Screening

Delirium occurrence in older Irish adults admitted to an acute medical hospital: a prospective cohort study Dolan, C. Mohd Zubir, M. Melvin, V. McCarthy, G. Meagher, D. Adamis, D. Ir J Psychol Med 2021

Delirium
epidemiology
incidence
inpatient
older adults
prevalence

Clinical utility of brain computed tomography in prediction of post-stroke delirium Czyzycki, M. Glen, A. Slowik, A. Chrzan, R. Dziedzic, T. J Neural Transm (Vienna) 2021

Brain atrophy
Delirium
Prediction
Stroke
White matter changes

Risk factors for long-term cognitive impairment in ICU survivors: A multicenter, prospective cohort study Collet, M. O. Egerod, I. Thomsen, T. Wetterslev, J. Lange, T. Ebdrup, B. H. Perner, A. Acta Anaesthesiol Scand 2021
Integration of family caregivers in delirium prevention care for hospitalized older adults: A case study analysis Cohen, C. Pereira, F. Kampel, T. Bélanger, L. J Adv Nurs 2021

Aged
Caregivers
Communication
Delirium/prevention & control
Family
Geriatric Nursing
Hospitalization
Humans
delirium
family caregivers
integration
nurses
older adults
orthopaedic surgery
prevention

Investigating how electroencephalogram measures associate with delirium: A systematic review Boord, M. S. Moezzi, B. Davis, D. Ross, T. J. Coussens, S. Psaltis, P. J. Bourke, A. Keage, H. A. D. Clin Neurophysiol 2021

Delirium
Eeg
Electroencephalography
Review

Pharmacologic Management of Intensive Care Unit Delirium: Clinical Prescribing Practices and Outcomes in More Than 8500 Patient Encounters Boncyk, C. S. Farrin, E. Stollings, J. L. Rumbaugh, K. Wilson, J. E. Marshall, M. Feng, X. Shotwell, M. S. Pandharipande, P. P. Hughes, C. G. Anesth Analg 2021
Predictors of delirium in older patients at the emergency department: a prospective multicentre derivation study Béland, E. Nadeau, A. Carmichael, P. H. Boucher, V. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Vu, T. T. M. Émond, M. CJEM 2021

Delirium
Emergency department
Predictor factors

Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort Atkins, J. L. Pilling, L. C. Heales, C. J. Savage, S. Kuo, C. L. Kuchel, G. A. Steffens, D. C. Melzer, D. J Alzheimers Dis 2021

Cohort
delirium
dementia
gene
hemochromatosis
iron
mutation

Awareness of Delirium by ICU Nurses Asmar, I. T. Yaseen, K. S. Jaghama, M. K. Khawaja, Y. F. Alwredat, A. A. Sadaqa, M. H. Crit Care Nurs Q 2021
Psychiatric Clinical Profiles and Pharmacological Interactions in COVID-19 Inpatients Referred to a Consultation Liaison Psychiatry Unit: a Cross-Sectional Study Arbelo, N. López-Pelayo, H. Sagué, M. Madero, S. Pinzón-Espinosa, J. Gomes-da-Costa, S. Ilzarbe, L. Anmella, G. Llach, C. D. Imaz, M. L. Cámara, M. M. Pintor, L. Psychiatr Q 2021

Covid-19
Consultation-liaison psychiatry
Delirium
Mental health residential facilities
Pharmacological interactions
Psychopharmacology

Octogenarian patients' sleep and delirium experiences in hospital and four years after aortic valve replacement: a qualitative interview study Amofah, H. A. Broström, A. Instenes, I. Fridlund, B. Haaverstad, R. Kuiper, K. Ranhoff, A. H. Norekvål, T. M. BMJ Open 2021

Aged, 80 and over
Aortic Valve/surgery
Aortic Valve Stenosis/surgery
Delirium/epidemiology/etiology
Female
Heart Valve Prosthesis Implantation/adverse effects
Hospitals
Humans
Male
Prospective Studies
Risk Factors
Sleep
Treatment Outcome
cardiac surgery
coronary intervention
delirium & cognitive disorders
qualitative research
sleep medicine
valvular heart disease

Delirium and quality of life in critically ill patients: a prospective cohort study Luz, L. F. D. S. Santos, M. C. D. Ramos, T. A. Almeida, C. B. Rover, M. C. Dal'Pizzol, C. P. Pohren, C. L. D. S. Martins, A. V. D. S. Boniatti, M. M. Rev Bras Ter Intensiva 2020

adult
article
Barthel index
cognitive defect
cohort analysis
controlled study
critically ill patient
female
functional status
hospital discharge
human
intensive care unit
major clinical study
male
Mini Mental State Examination
physical disability
prospective study
quality of life
questionnaire
telephone
World Health Organization

Bispectral Index Monitoring With Density Spectral Array for Delirium Detection Luo, A. Muraida, S. Pinchotti, D. Richardson, E. Ye, E. Hollingsworth, B. Win, A. Myers, O. Langsjoen, J. Valles, E. Zolyomi, A. Quinn, D. K. Psychosomatics 2020

bispectral index monitoring
delirium
density spectral array

Delirium prediction in the intensive care unit: a temporal approach Lucini, F. R. Fiest, K. M. Stelfox, H. T. Lee, J. Annu Int Conf IEEE Eng Med Biol Soc 2020

Alberta
Delirium/diagnosis
Humans
Intensive Care Units
Logistic Models
Retrospective Studies

Impact of place of residence, frailty and other factors on rehabilitation outcomes post hip fracture Low, S. Wee, E. Dorevitch, M. Age Ageing 2020

clinical frailty scale
frailty
hip fracture
older people
rehabilitation
residential care

Ramelteon for Decreasing Delirium in Surgical Intensive Care Unit Patients Lopez, C. N. Fuentes, A. Dhala, A. Balk, J. Clinical Medicine Insights: Psychiatry 2020

haloperidol
lorazepam
melatonin
neuroleptic agent
quetiapine
ramelteon
risperidone
acute disease
adult
article
artificial ventilation
cardiovascular surgery
clinical assessment
clinical evaluation
cognitive defect
cohort analysis
comparative study
confusion
delirium
disease severity
female
hemodynamics
hospital admission
hospitalization
human
incidence
intensive care unit
length of stay
liver transplantation
major clinical study
male
middle aged
Model For End Stage Liver Disease Score
mortality rate
priority journal
retrospective study
risk factor
Sequential Organ Failure Assessment Score
surgical intensive care unit

Different depths of sedation versus risk of delirium in adult mechanically ventilated patients: A systematic review and meta-analysis Long, L. Ren, S. Gong, Y. Zhao, H. He, C. Shen, L. Zhao, H. Ma, P. PLoS One 2020

Adult
Conscious Sedation/ adverse effects
Delirium/ etiology/pathology
Humans
Hypnotics and Sedatives/ adverse effects
Length of Stay
Respiration, Artificial/ adverse effects
Ventilators, Mechanical/ adverse effects

Association of Troponin Levels With Mortality in Italian Patients Hospitalized With Coronavirus Disease 2019: Results of a Multicenter Study Lombardi, C. M. Carubelli, V. Iorio, A. Inciardi, R. M. Bellasi, A. Canale, C. Camporotondo, R. Catagnano, F. Dalla Vecchia, L. A. Giovinazzo, S. Maccagni, G. Mapelli, M. Margonato, D. Monzo, L. Nuzzi, V. Oriecuia, C. Peveri, G. Pozzi, A. Provenzale, G. S JAMA Cardiol 2020

Aged
Aged, 80 and over
COVID-19/ blood/epidemiology/ mortality/virology
Cardiovascular Diseases/ blood/epidemiology
Comorbidity
Cross-Sectional Studies
Female
Hospital Mortality/trends
Hospitalization/statistics & numerical data
Humans
Italy/epidemiology
Male
Middle Aged
Prevalence
Risk Factors
SARS-CoV-2/ genetics
Troponin I/blood
Troponin T/blood

Role of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis Liu, X. Xiong, J. Tang, Y. Gong, C. C. Wang, D. F. Minerva anestesiologica 2020

adult
article
bradycardia
clinical trial
Cochrane Library
comparative effectiveness
critically ill patient
delirium
drug efficacy
drug safety
drug therapy
Embase
female
human
incidence
male
Medline
pharmacokinetics
prevalence
randomized controlled trial (topic)
systematic review
Web of Science
dexmedetomidine
haloperidol
placebo

Delirium Severity Trajectories and Outcomes in ICU Patients. Defining a Dynamic Symptom Phenotype Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. Ann Am Thorac Soc 2020

critical care
delirium
delirium severity
prediction
trajectory of illness

Risk factors for postoperative delirium in patients with triple-branched stent graft implantation Lin, Y. Chen, Q. Zhang, H. Chen, L. W. Peng, Y. Huang, X. Chen, Y. Li, S. Lin, L. J Cardiothorac Surg 2020

Apache
Aneurysm, Dissecting/ surgery
Aortic Aneurysm, Thoracic/ surgery
Delirium/ etiology
Female
Humans
Incidence
Japan
Male
Middle Aged
Postoperative Complications/ etiology
Proportional Hazards Models
Retrospective Studies
Risk Factors
Stents
Aortic dissection
Postoperative delirium
Triple-branched stent graft implantation

Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study Lin, X. Tang, J. Liu, C. Li, X. Cao, X. Wang, B. Dong, R. Xu, W. Yu, X. Wang, M. Bi, Y. BMC Anesthesiol 2020

Cerebrospinal fluid
Cholinergic
Elderly
Postoperative delirium

Effect of Dexmedetomidine on Delirium in Elderly Surgical Patients: A Meta-analysis of Randomized Controlled Trials Lin, C. Tu, H. Jie, Z. Zhou, X. Li, C. Ann Pharmacother 2020

delirium
dexmedetomidine
elderly surgical patients
meta-analysis

The relationship between intraoperative cerebral oximetry and postoperative delirium in patients undergoing off-pump coronary artery bypass graft surgery: a retrospective study Lim, L. Nam, K. Lee, S. Cho, Y. J. Yeom, C. W. Jung, S. Moon, J. Y. Jeon, Y. BMC Anesthesiol 2020

Cerebral oximetry
Delirium
Off-pump coronary artery bypass graft surgery

Effects of nonpharmacological delirium-prevention interventions on critically ill patients' clinical, psychological, and family outcomes: A systematic review and meta-analysis Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Choi, K. C. Aust Crit Care 2020

Delirium
Intensive care units
Meta-analysis
Systematic review

Validation of PREdiction of DELIRium in ICu patients (PRE-DELIRIC) among patients in intensive care units: A retrospective cohort study Liang, S. Chau, J. P. C. Lo, S. H. S. Bai, L. Yao, L. Choi, K. C. Nurs Crit Care 2020

Icu
Predeliric
delirium
prevention
risk factor

Prognostic Impact of Delirium in Older People With/Without Dementia: A Retrospective Cohort Study in Taiwan Liang, C. K. Chuang, H. Y. Hsiao, F. Y. Chou, M. Y. Liu, T. Y. Yang, C. C. Chen, L. K. Journal of Nutrition, Health and Aging 2020

aged
article
awareness
cohort analysis
controlled study
delirium
dementia
emergency ward
female
follow up
health care utilization
hospital readmission
human
major clinical study
male
mortality
national health insurance
prognosis
propensity score
public hospital
retrospective study
Taiwan
psychotropic agent

Effects of modified version of the Hospital Elder Life Program on post-discharge cognitive function and activities of daily living among older adults undergoing total knee arthroplasty Liang, C. K. Chu, C. S. Hsu, Y. H. Chou, M. Y. Wang, Y. C. Lin, Y. T. Renn, J. H. Liu, T. Y. Yang, C. C. Arch Gerontol Geriatr 2020

Cognitive decline
Delirium
Functional decline
Intervention
Total knee arthroplasty

Incidence and Risk Factors for Delirium in Older Patients Following Intensive Care Unit Admission: A Prospective Observational Study Li, X. Zhang, L. Gong, F. Ai, Y. The journal of nursing research : JNR 2020

aged
article
China
controlled study
critically ill patient
delirium
demography
doctor nurse relation
female
human
incidence
intensive care unit
major clinical study
male
observational study
prospective study
Richmond Agitation Sedation Scale
risk factor
sleep quality
fentanyl

Surviving and Thriving 1 Year After Cardiac Surgery: Frailty and Delirium Matter Li, H. C. Wei, Y. C. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. H. Inouye, S. K. Annals of Thoracic Surgery 2020

ADL disability
adult
all cause mortality
article
Barthel index
controlled study
female
frailty
heart surgery
human
major clinical study
male
phenotype
postoperative delirium
preoperative evaluation
prevention
surgery
university hospital

Pharmacist Identification of Medication Therapy Problems Involving Cognition Among Older Adults Followed by a Home-Based Care Team Levine, A. M. P. Emonds, E. E. Smith, M. A. Rickles, N. M. Kuchel, G. A. Steffens, D. C. Ohlheiser, A. Fortinsky, R. H. Drugs and Aging 2020

aged
article
clinical pharmacist
cognition
Connecticut
controlled study
dementia
drug megadose
drug overdose
drug safety
drug therapy
drug withdrawal
female
geriatrician
human
International Classification of Diseases
low drug dose
major clinical study
male
medicare
medication therapy management
multidisciplinary team
pharmacokinetics
potentially inappropriate medication
primary medical care
psychiatrist
randomized controlled trial
registered nurse
retrospective study
side effect
antidepressant agent
benzodiazepine derivative
cholinergic receptor blocking agent

Multicomponent Interventions for the Prevention of Delirium in Hospitalized Older People: A Meta-Analysis León-Salas, B. Trujillo-Martín, M. M. Martínez Del Castillo, L. P. García-García, J. Pérez-Ros, P. Rivas-Ruiz, F. Serrano-Aguilar, P. J Am Geriatr Soc 2020

delirium
hospitalization
meta-analysis
multicomponent
older people
prevention

Pharmacologic interventions for prevention of delirium in hospitalized older people: A meta-analysis León-Salas, B. Trujillo-Martín, M. M. Del Castillo, L. P. M. García, J. G. Pérez-Ros, P. Ruiz, F. R. Serrano-Aguilar, P. Arch Gerontol Geriatr 2020

Aged
Aged, 80 and over
Antipsychotic Agents/therapeutic use
Delirium/drug therapy/prevention & control
Humans
Incidence
Postoperative Complications
Time Factors
Delirium
Hospitalization
Meta-Analysis
Older
Pharmacologic intervention
Prevention

"You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. J Clin Nurs 2020

Aged
Aged, 80 and over
Critical Care Nursing/ methods
Delirium/nursing/ prevention & control/psychology
Female
Hospitalization
Humans
Male
Nurse-Patient Relations
Patient-Centered Care/ methods
Qualitative Research
adult
awareness
caregivers
delirium
exercise
inpatients
perception

The Effect of Intraoperative Magnesium Sulphate Infusion on Emergence Agitation after Ambulatory Ophthalmic Surgery in Children Lee, Y. J. Kim, B. Y. Park, J. H. Kim, S. Y. Park, H. Y. Do, S. H. J Clin Med 2020

ambulatory surgery
emergence agitation
magnesium sulphate
ophthalmic surgery
paediatric patients

Effects of the ABCDE bundle on the prevention of post-intensive care syndrome: A retrospective study Lee, Y. Kim, K. Lim, C. Kim, J. S. Journal of advanced nursing 2020

adult
aged
chronic disease
coma
comparative study
critical illness
delirium
female
human
intensive care
length of stay
male
middle aged
nursing
physiology
procedures
retrospective study
survivor
very elderly
walking

Effect of Antipsychotics and Non-Pharmacotherapy for the Management of Delirium in People Receiving Palliative Care Lee, K. Y. Tan, E. C. K. Hanrahan, J. R. Chircop, C. Michael, F. Ong, J. A. J Pain Palliat Care Pharmacother 2020

Delirium
anti-psychotics
palliative care

Effect of magnesium supplementation on emergence delirium and postoperative pain in children undergoing strabismus surgery: a prospective randomised controlled study Lee, J. H. Choi, S. Lee, M. Jang, Y. E. Kim, E. H. Kim, J. T. Kim, H. S. BMC Anesthesiol 2020

Emergence delirium
Magnesium
Ophthalmologic surgical procedure
Paediatrics
Pain

Neurologic Complications in Patients With Cancer Lee, E. Q. Continuum (Minneapolis, Minn.) 2020

adult
article
aspergillosis
blood clotting
brain hemorrhage
cancer patient
central nervous system infection
cerebrovascular accident
chimeric antigen receptor T-cell immunotherapy
complication
delirium
diagnosis
differential diagnosis
early diagnosis
effector cell
human
neurological complication
angiogenesis inhibitor
ibrutinib

Melatonin to prevent delirium in patients with advanced cancer: a double blind, parallel, randomized, controlled, feasibility trial Lawlor, P. G. McNamara-Kilian, M. T. MacDonald, A. R. Momoli, F. Tierney, S. Lacaze-Masmonteil, N. Dasgupta, M. Agar, M. Pereira, J. L. Currow, D. C. Bush, S. H. BMC Palliat Care 2020

Advanced cancer
Delirium
Feasibility study
Melatonin
Pilot
Prevention
Randomized controlled trial
Sleep

Cognitive function and health-related quality of life 1 year after acute brain injury: An observational study Larsen, L. K. Møller, K. Petersen, M. Egerod, I. Acta Anaesthesiol Scand 2020

Acute brain injury
cognitive impairment
delirium
health-related quality of life
neuro intensive care unit

The One-Two Punch of Delirium and Dementia During the COVID-19 Pandemic and Beyond LaHue, S. C. Douglas, V. C. Miller, B. L. Front Neurol 2020

Alzheimer’s disease and related dementias (ADRD)
Covid-19
accessibility
delirium
dementia
hospitalization
technology

Postoperative Delirium is a Risk Factor of Poor Evolution Three Years After Cardiac Surgery: An Observational Cohort Study Labaste, F. Porterie, J. Bousquet, P. Marcheix, B. Sanchez-Verlaan, P. Frances, B. Valet, P. Dray, C. Minville, V. Clin Interv Aging 2020

cardiac surgery
delirium
dependence
mortality
quality of life

Delirium among Hospitalized Older Adults with Acute Heart Failure Exacerbation Kwak, M. J. Avritscher, E. Holmes, H. M. Jantea, R. Flores, R. Rianon, N. Chung, T. H. Balan, P. Dhoble, A. J Card Fail 2020

Acute Heart Failure
Delirium
Hospital Cost
Length of Stay
Older Adults

Association between polypharmacy and the persistence of delirium: a retrospective cohort study Kurisu, K. Miyabe, D. Furukawa, Y. Shibayama, O. Yoshiuchi, K. Biopsychosoc Med 2020

Classification and regression tree
Delirium
Polypharmacy
Propensity score
Receiver operating characteristic curve

Elevated Procalcitonin as a Risk Factor for Postoperative Delirium in the Elderly after Cardiac Surgery-A Prospective Observational Study Kupiec, A. Adamik, B. Kozera, N. Gozdzik, W. J Clin Med 2020

cardiac surgery
delirium
depression
elderly
functional decline
procalcitonin

The CAM-ICU-7 and ICDSC as measures of delirium severity in critically ill adult patients Krewulak, K. D. Rosgen, B. K. Ely, E. W. Stelfox, H. T. Fiest, K. M. PLoS One 2020

Adult
Aged
Critical Care/methods
Critical Illness/ classification
Cross-Sectional Studies
Delirium/ classification/diagnosis
Female
Humans
Intensive Care Units
Length of Stay/statistics & numerical data
Logistic Models
Male
Mass Screening/ methods
Middle Aged
Odds Ratio
Prevalence

Adaptation and Validation of a Chart-Based Delirium Detection Tool for the ICU (CHART-DEL-ICU) Krewulak, K. D. Hiploylee, C. Ely, E. W. Stelfox, H. T. Inouye, S. K. Fiest, K. M. J Am Geriatr Soc 2020

Confusion Assessment Method for Intensive Care Unit (CAM-ICU)
Intensive Care Delirium Screening Checklist (ICDSC)
critical care
delirium screening
intensive care unit

Effectiveness of an intensive care unit family education intervention on delirium knowledge: a pre-test post-test quasi-experimental study Krewulak, K. D. Bull, M. J. Wesley Ely, E. Davidson, J. E. Stelfox, H. T. Fiest, K. M. Can J Anaesth 2020

Critical care
Delirium education
Family
Intensive care unit

Assessment and Management of Delirium in Critically Ill Veterans Kresevic, D. M. Miller, D. Fuseck, C. W. Wade, M. Whitney, L. Conley, M. Rimac, J. Jacono, F. O'Leary-Wilson, H. L. Burant, C. J. Critical care nurse 2020

article
breathing
controlled study
critically ill patient
delirium
doctor nurse relation
education program
hip
human
leadership
medical record
pain assessment
screening test
sedation
simulation training
surgical intensive care unit
total quality management
veteran

Delirium Post-Stroke: Short- and Long-Term Effect on Depression, Anxiety, Apathy and Aggression (Research Study-Part of PROPOLIS Study) Kowalska, K. Droś, J. Mazurek, M. Pasińska, P. Gorzkowska, A. Klimkowicz-Mrowiec, A. J Clin Med 2020

aggression
anxiety
apathy
depression
post-stroke delirium
stroke

Intrathecal Morphine Is Associated with Less Delirium Following Hip Fracture Surgery: A Register Study Koning, M. V. van der Sijp, M. Stolker, R. J. Niggebrugge, A. Anesth Pain Med 2020

Delirium
Femoral Fractures
Morphine
Spinal Anesthesia
Spinal Injections

Evaluation of Pediatric Delirium Awareness and Management in Pediatric Intensive Care Units in Turkey Konca, C. Anil, A. B. Küllüoglu, E. P. Luleyap, D. Anil, M. Tekin, M. Journal of Pediatric Intensive Care 2020

Awareness

Delirium

Management

Pediatric

Turkey

Preventive effect of ramelteon on emergence agitation after general anaesthesia in paediatric patients undergoing tonsillectomy: a randomised, placebo-controlled clinical trial Komazaki, M. Mihara, T. Nakamura, N. Ka, K. Goto, T. Sci Rep 2020
Delirium in burn patients: developing a mobile application for assessment and diagnosis Kolaei, N. M. M. Ayatollahi, H. Elyasi, F. J Burn Care Res 2020

Burn
Delirium
Delirium screening
Mobile application

Delirium at the end of life Knoepfel, S. Bode, L. Gehrke, S. Spiller, T. Fuchs, S. Ernst, J. von Känel, R. Boettger, S. Palliat Support Care 2020

Delirium at the end of life
In-hospital mortality
Interrelationship of delirium and death
Terminal delirium

Protocol for the effectiveness of an anesthesiology control tower system in improving perioperative quality metrics and clinical outcomes: The tectonics randomized, pragmatic trial King, C. R. Abraham, J. Kannampallil, T. G. Fritz, B. A. Abdallah, A. B. Chen, Y. Henrichs, B. Politi, M. Torres, B. A. Mickle, A. Budelier, T. P. McKinnon, S. Gregory, S. Kheterpal, S. Wildes, T. Avidan, M. S. Tectonics Research, Group F1000Research 2020

NCT02032030
NCT03923699
AlertWatch
anesthesiology control tower system
anesthesiology monitoring device
operating room
antibiotic agent
glucose
acute kidney failure
adult
airway pressure
anesthesia level
article
artificial ventilation
clinical effectiveness
clinical outcome
clinical protocol
controlled study
gas flow
glucose blood level
human
intention to treat analysis
major clinical study
mean airway pressure
mean arterial pressure
perioperative period
phase 3 clinical trial
postoperative delirium
randomized controlled trial
respiratory failure
surgical mortality
surgical technique
temperature measurement

Sleep disturbance and delirium in patients with acromegaly in the early postoperative period after transsphenoidal pituitary surgery Kim, S. H. Kim, N. Min, K. T. Kim, E. H. Oh, H. Choi, S. H. Medicine (Baltimore) 2020

Acromegaly/ surgery
Adult
Aged
Delirium/ epidemiology
Endocrine Surgical Procedures/methods
Female
Humans
Incidence
Male
Middle Aged
Pituitary Neoplasms/ surgery
Postoperative Complications/ epidemiology
Retrospective Studies
Sleep Wake Disorders/ epidemiology
Sphenoid Sinus
Time Factors

Frontal electroencephalogram activity during emergence from general anaesthesia in children with and without emergence delirium Kim, J. Lee, H. C. Byun, S. H. Lim, H. Lee, M. Choung, Y. Kim, E. Br J Anaesth 2020

brain waves
children
electroencephalogram (EEG)
emergence delirium
neurocognitive disorders
post operative delirium
sevoflurane anaesthesia

Safety and efficacy of pharmacologic agents used for rapid tranquilization of emergency department patients with acute agitation or excited delirium Kim, H. K. Leonard, J. B. Corwell, B. N. Connors, N. J. 2020

acute agitation
emergency department
excited delirium
excited delirium syndrome
rapid tranquilization
safety

Effect of Timing of Intravenous Fentanyl Administration on the Incidence of Posttonsillectomy Nausea and Vomiting Kim, H. J. Kim, M. S. Kim, H. Y. Park, W. K. Kim, W. S. Kim, S. Kim, H. J. Laryngoscope 2020

Postoperative nausea and vomiting
emergence delirium
fentanyl
pain, postoperative
tonsillectomy

Effect on Quality of Care of a Delirium Prevention Campaign for Surgical Intensive Care Nurses Kim, H. Lee, S. M. Publish Ahead of Print 2020
Ultrasound-Guided Pecto-Intercostal Fascial Block for Postoperative Pain Management in Cardiac Surgery: A Prospective, Randomized, Placebo-Controlled Trial Khera, T. Murugappan, K. R. Leibowitz, A. Bareli, N. Shankar, P. Gilleland, S. Wilson, K. Oren-Grinberg, A. Novack, V. Venkatachalam, S. Rangasamy, V. Subramaniam, B. J Cardiothorac Vasc Anesth 2020

3-minute diagnostic Confusion Assessment Method
3d-cam
Pifb
Pecto-intercostal fascial plane block
Vas
cardiac surgery
pain scores
postoperative delirium
visual analog scale

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019 Khan, S. H. Lindroth, H. Perkins, A. J. Jamil, Y. Wang, S. Roberts, S. Farber, M. Rahman, O. Gao, S. Marcantonio, E. R. Boustani, M. Machado, R. Khan, B. A. Crit Care Explor 2020

brain diseases
coma
coronavirus disease 2019
critical illness
delirium
respiratory insufficiency

Delirium, Cerebral Perfusion and High Frequency Vital Sign Monitoring in the Critically Ill: The CONFOCAL-2 Feasibility Study Khan, J. M. Wood, M. D. Lee, K. F. H. Maslove, D. Muscedere, J. English, S. W. Ball, I. Slessarev, M. Boyd, J. G. Annals of the American Thoracic Society 2020

NCT03141619
adult
area under the curve
arterial line
article
artificial ventilation
autoregulation
blood gas
brain perfusion
cognitive defect
controlled study
critically ill patient
feasibility study
female
follow up
forehead
heart rate
human
intensive care unit
major clinical study
male
mean arterial pressure
multicenter study
near infrared spectroscopy
observational study
prospective study
respiratory failure
sensor
tissue oxygenation
vital sign

Melatonin for delirium prevention in hospitalized patients: A systematic review and meta-analysis Khaing, K. Nair, B. R. J Psychiatr Res 2020

Delirium
ICU delirium
Melatonin in delirium prevention
Postoperative delirium
Ramelteon in delirium prevention

Delirium in Older Patients With COVID-19 Presenting to the Emergency Department Kennedy, M. Helfand, B. K. I. Gou, R. Y. Gartaganis, S. L. Webb, M. Moccia, J. M. Bruursema, S. N. Dokic, B. McCulloch, B. Ring, H. Margolin, J. D. Zhang, E. Anderson, R. Babine, R. L. Hshieh, T. Wong, A. H. Taylor, R. A. Davenport, K. Teresi, B. Fong, T. JAMA Netw Open 2020

Aged
Aged, 80 and over
COVID-19/ diagnosis/physiopathology
Cohort Studies
Delirium/ diagnosis/physiopathology
Emergency Service, Hospital
Female
Geriatric Assessment
Humans
Intensive Care Units
Male
Middle Aged
Patient Admission/statistics & numerical data
Psychomotor Agitation/ diagnosis/physiopathology
Risk Factors
SARS-CoV-2

Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: A prospective observational study of delirium in elderly cardiac surgical patients Kendall Smith, S. Nguyen, T. Labonte, A. K. Kafashan, M. Hyche, O. Guay, C. S. Wilson, E. Chan, C. W. Luong, A. Brian Hickman, L. Fritz, B. A. Emmert, D. Graetz, T. J. Melby, S. J. Lucey, B. P. Ju, Y. E. S. Wildes, T. S. Avidan, M. S. Palanca, B. J. A. BMJ Open 2020

aged
article
cardiopulmonary bypass
cognitive defect
controlled study
diagnosis
electroencephalography
ethics
female
heart surgery
human
intensive care
major clinical study
male
mass medium
neurophysiology
observational study
postoperative delirium
prospective study
psychiatry
quantitative analysis
remission
sleep medicine
sleep spindle
speech
surgery
surgical patient
wakefulness
Washington

Prevalence of Geriatric Syndromes and the Need for Hospice Care in Older Patients of the Emergency Department: A Study in an Asian Medical Center Ke, Y. T. Peng, A. C. Shu, Y. M. Chung, M. H. Tsai, K. T. Chen, P. J. Weng, T. C. Hsu, C. C. Lin, H. J. Huang, C. C. Emergency Medicine International 2020

advance care planning
aged
article
caregiver
controlled study
daily life activity
decubitus
delirium
dementia
depression
emergency care
falling
female
geriatric assessment
geriatric care
geriatric disorder
hearing impairment
hospice care
human
major clinical study
male
nutritional disorder
pain
polypharmacy
sleep disorder
socioeconomics
Taiwan
urine incontinence
urine retention
very elderly
visual impairment

The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium Katsumi, Y. Racine, A. M. Torrado-Carvajal, A. Loggia, M. L. Hooker, J. M. Greve, D. N. Hightower, B. G. Catana, C. Cavallari, M. Arnold, S. E. Fong, T. G. Vasunilashorn, S. M. Marcantonio, E. R. Schmitt, E. M. Xu, G. Libermann, T. A. Barrett, L. F. Inouy NeuroImage: Clinical 2020

PET-MRI scanner
biological marker
C reactive protein
chitinase 3 like protein 1
interleukin 6
pbr 28
pbr 28 c 11
tracer
unclassified drug
aged
article
central nervous system
cerebrospinal fluid
cognitive defect
cohort analysis
disease severity
disease severity assessment
down regulation
female
hospitalization
human
immunoregulation
immunostimulation
incidence
major clinical study
major surgery
male
nervous system inflammation
nuclear magnetic resonance imaging
orthopedic surgery
peripheral nervous system
positron emission tomography
postoperative delirium
preoperative evaluation
priority journal
Biograph mMR

Association between visitation restriction during the COVID-19 pandemic and delirium incidence among emergency admission patients: a single-center retrospective observational cohort study in Japan Kandori, K. Okada, Y. Ishii, W. Narumiya, H. Maebayashi, Y. Iizuka, R. Journal of Intensive Care 2020

adult
aged
article
cohort analysis
coronavirus disease 2019
delirium
dementia
emergency health service
emergency patient
emergency ward
female
general anesthesia
hospital patient
human
incidence
intensive care
Japan
major clinical study
male
outcome assessment
pandemic
retrospective study
ventilator

Intensive Care Unit Nurses’ Beliefs About Delirium Assessment and Management Kimberly J. Oosterhouse, RN, PhD Catherine Vincent, RN, PhD Marquis D. Foreman, RN, PhD Valerie A. Gruss, PhD, APRN Colleen Corte, RN, PhD Barbara Berger, RN, PhD AACN Adv Crit Care 2016

beliefs; critical care nurses; delirium; older adult; vignettes

Using Concept Unique Identifiers to Filter Electronic Health Records for Delirium Cases Kimberly J. Oosterhouse, PhD, RN, Cynthia D. Young, MSN, RN, Manushi Desai, MBA, RN, Steven Birch, BS, Ron Price, Jr, BA, Kathleen L. Bobay, PhD, RN, FAAN CIN: Computers, Informatics, Nursing 2021

Concept unique identifiers, Delirium,
Electronic health records, Older adults, Unified Medical
Language System

Delirium incidence, risk factors, and treatments in older adults receiving chemotherapy: A systematic review and meta-analysis Jung, P. Puts, M. Frankel, N. Syed, A. T. Alam, Z. Yeung, L. Malik, U. Rosario, C. Ayala, A. P. Hudson, J. Alibhai, S. M. H. J Geriatr Oncol 2020

Aged
Chemotherapy
Delirium
Geriatric oncology
Systematic review
Toxicity

Postoperative delirium: perioperative assessment, risk reduction, and management Jin, Z. Hu, J. Ma, D. Br J Anaesth 2020

Blood Transfusion
Delirium/prevention & control/ therapy
Fluid Therapy
Humans
Pain Management
Postoperative Complications/prevention & control/ therapy
Preoperative Care
Risk Assessment
Risk Reduction Behavior
delirium
neurocognitive dysfunction
pharmacotherapy
postoperative cognitive dysfunction
prevention
risk management

Platelet-to-lymphocyte ratio as a predictive index for delirium in critically ill patients: A retrospective observational study Jiang, X. Shen, Y. Fang, Q. Zhang, W. Cheng, X. Medicine (Baltimore) 2020

Aged
Blood Gas Monitoring, Transcutaneous/methods
Blood Platelets/ cytology
Case-Control Studies
China/epidemiology
Critical Illness/ psychology
Delirium/ blood/diagnosis/epidemiology/physiopathology
Female
Humans
Incidence
Inflammation/metabolism/pathology
Inhalation/physiology
Intensive Care Units
Lymphocytes/ cytology
Male
Middle Aged
Oxygen/analysis
Predictive Value of Tests
Respiration, Artificial/statistics & numerical data
Retrospective Studies

Validation of the 3-minute diagnostic interview for CAM-defined Delirium in Chinese older adults Ji, M. Wang, J. Yang, X. Huang, Y. Xiao, Y. Wu, Y. Geriatr Nurs 2020

3d-cam
Delirium
Older adult
Sensitivity and specificity

Diagnostic Test Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis Jeong, E. Park, J. Lee, J. Int J Environ Res Public Health 2020

4at
delirium
meta-analysis
sensitivity
specificity
systematic review

Development and Evaluation of Clinical Practice Guideline for Delirium in Long-Term Care Jeong, E. Park, J. Chang, S. O. Int J Environ Res Public Health 2020

aged
delirium
guideline
long-term care
nursing home

Risk prediction of delirium in hospitalized patients using machine learning: An implementation and prospective evaluation study Jauk, S. Kramer, D. Großauer, B. Rienmüller, S. Avian, A. Berghold, A. Leodolter, W. Schulz, S. J Am Med Inform Assoc 2020

Machine learning
clinical decision support
delirium
electronic health records
prospective studies

Objectively measured sleep fragmentation is associated with incident delirium in older hospitalized patients: Analysis of data collected from an randomized controlled trial Jaiswal, S. J. Kang, D. Y. Wineinger, N. E. Owens, R. L. J Sleep Res 2020

actigraphy
delirium
melatonin
sleep

Incidence and predictors of delirium on the intensive care unit after acute myocardial infarction, insight from a retrospective registry Jäckel, M. Zotzmann, V. Wengenmayer, T. Duerschmied, D. Biever, P. M. Spieler, D. von Zur Mühlen, C. Stachon, P. Bode, C. Staudacher, D. L. Catheter Cardiovasc Interv 2020

NuDesc
delirium
intensive care unit
myocardial infarction

Real-World Preventive Effects of Suvorexant in Intensive Care Delirium: A Retrospective Cohort Study Izuhara, M. Izuhara, H. K. Tsuchie, K. Araki, T. Ito, T. Sato, K. Miura, S. Otsuki, K. Nagahama, M. Hayashida, M. Hashioka, S. Wake, R. Kimura, T. Tsumoto, S. Saito, Y. Inagaki, M. J Clin Psychiatry 2020

Adolescent
Adult
Aged
Aged, 80 and over
Azepines/ administration & dosage
Child
Child, Preschool
Critical Care/methods/ statistics & numerical data
Delirium/epidemiology/ prevention & control
Female
Humans
Male
Middle Aged
Orexin Receptor Antagonists/ administration & dosage
Outcome Assessment, Health Care/ statistics & numerical data
Prevalence
Proportional Hazards Models
Retrospective Studies
Serotonin Uptake Inhibitors/pharmacology
Sleep Initiation and Maintenance Disorders/ drug therapy
Trazodone/pharmacology
Triazoles/ administration & dosage
Young Adult

Prognostic Value of Delirium in Patients With Acute Heart Failure in the Intensive Care Unit Iwata, E. Kondo, T. Kato, T. Okumura, T. Nishiyama, I. Kazama, S. Ishihara, T. Kondo, S. Hiraiwa, H. Tsuda, T. Ito, M. Aoyama, M. Tanimura, D. Awaji, Y. Unno, K. Murohara, T. Canadian Journal of Cardiology 2020

acute heart failure
adult
adverse outcome
age
aged
article
delirium
dementia
disease severity
female
hospital mortality
human
intensive care unit
major clinical study
male
mortality rate
nursing home patient
prognosis
prospective study
risk factor

Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. Int J Oral Maxillofac Surg 2020

Delirium
Humans
Intensive Care Units
Mouth Neoplasms
Postoperative Complications
Reconstructive Surgical Procedures
Retrospective Studies
Risk Factors
oral tumor
postoperative delirium
reconstructive surgery

Vitamin D status and complications, readmissions, and mortality after hip fracture Ingstad, F. Solberg, L. B. Nordsletten, L. Thorsby, P. M. Hestnes, I. Frihagen, F. Osteoporos Int 2020

Delirium
Fracture healing
Hip fracture
Post-fracture complications
Prevention
Vitamin D deficiency

Multi-disciplinary and pharmacological interventions to reduce post-operative delirium in elderly patients: A systematic review and meta-analysis Igwe, E. O. Nealon, J. Mohammed, M. Hickey, B. Chou, K. R. Chen, J. K. Traynor, V. Journal of Clinical Anesthesia 2020

bupivacaine
dexmedetomidine
haloperidol
placebo
pregabalin
propofol
sevoflurane
checklist
confidence interval
emergency surgery
geriatric care
high risk population
human
meta analysis
postoperative care
postoperative delirium
priority journal
review
statistically significant result
systematic review

Preoperative serum biomarkers in the prediction of postoperative delirium following abdominal surgery Ida, M. Takeshita, Y. Kawaguchi, M. Geriatr Gerontol Int 2020

biomarker
delirium
inflammation
postoperative period

Rotigotine patch prescription in inpatients with Parkinson's disease: evaluating prescription accuracy, delirium and end-of-life use Ibrahim, H. Woodward, Z. Pooley, J. Richfield, E. W. Age Ageing 2020

Parkinson’s disease
advance care planning
dysphagia
neuropharmacology
older people
palliative care

Effect of Cognitive Prehabilitation on the Incidence of Postoperative Delirium among Older Adults Undergoing Major Noncardiac Surgery: The Neurobics Randomized Clinical Trial Humeidan, M. L. Reyes, J. P. C. Mavarez-Martinez, A. Roeth, C. Nguyen, C. M. Sheridan, E. Zuleta-Alarcon, A. Otey, A. Abdel-Rasoul, M. Bergese, S. D. JAMA Surgery 2020

aged
article
attention
brain
cognitive defect
exercise
female
general anesthesia
hospitalization
human
incidence
major clinical study
medical record review
memory
Ohio
post hoc analysis
postoperative delirium
problem solving
prospective study
randomized controlled trial
risk assessment
secondary analysis
single blind procedure
surgery
tablet computer
velocity

Delirium in intensive care: violence, loss and humanity Hume, V. J. Med Humanit 2020

arts in health/arts and health
critical care/intensive care
music
psychology

Neuroleptic strategies for terminal agitation in patients with cancer and delirium at an acute palliative care unit: a single-centre, double-blind, parallel-group, randomised trial Hui, D. De La Rosa, A. Wilson, A. Nguyen, T. Wu, J. Delgado-Guay, M. Azhar, A. Arthur, J. Epner, D. Haider, A. De La Cruz, M. Heung, Y. Tanco, K. Dalal, S. Reddy, A. Williams, J. Amin, S. Armstrong, T. S. Breitbart, W. Bruera, E. Lancet Oncol 2020

Aged
Antipsychotic Agents/ therapeutic use
Delirium/ drug therapy/etiology/pathology
Double-Blind Method
Female
Follow-Up Studies
Haloperidol/ therapeutic use
Humans
Male
Middle Aged
Neoplasms/ complications/psychology/therapy
Palliative Care
Prognosis
Psychomotor Agitation/ drug therapy/etiology/pathology

Incidence and risk factors of delirium after percutaneous coronary intervention in individuals hospitalised for acute myocardial infarction: protocol for a systematic review and meta-analysis Huang, K. Lu, J. Zhu, Y. Cheng, T. Du, D. Qian, X. Pan, H. Wang, X. Yang, H. Lou, S. BMJ Open 2020

coronary intervention
delirium & cognitive disorders
myocardial infarction