Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
A large-scale causal analysis of gut microbiota and delirium: A Mendelian randomization study
Authors
Yu, H. Wan, X. Yang, M. Xie, J. Xu, K. Wang, J. Wang, G. Xu, P.
Year
2023
Journal
J Affect Disord
Abstract

BACKGROUND: Several studies have linked gut microbiota to human brain activity. This study used Mendelian randomization (MR) to investigate the causal relationship between gut microbes and delirium. METHODS: MR was used to select SNPs from large-scale GWAS summary data on 211 gut microbiota taxa and delirium. Inverse variance weighting (IVW), weighted median, and MR-Egger methods were used for statistical analyses. Outliers were assessed using the leave-one-out method. To avoid horizontal pleiotropy, we performed the MR-PRESSO and MR-Egger intercept tests. Cochran’s Q and I(2) values for IVW and MR-Egger were used to assess heterogeneity. RESULTS: IVW suggested that genetic prediction of the family Desulfovibrionaceae (1.784 (1.267-2.512), P = 0.001), order Desulfovibrionales (1.501 (1.058-2.128), P = 0.023), and genus Candidatus Soleaferrea (1.322 (1.052-1.659), P = 0.016) increased the risk of delirium, but the family Oxalobacteraceae (0.841 (0.722-0.981), P = 0.027), and genera Holdemania (0.766 (0.620-0.946), P = 0.013), Ruminococcus gnavus (0.806 (0.661-0.982), P = 0.033), and Eggerthella (0.815 (0.667-0.997), P = 0.047) reduced the risk of delirium. LIMITATIONS: (1) Limited sample size, (2) inability to assess gut microbiota interactions, and (3) limited to European populations. CONCLUSION: Our results suggest that presence of the microbial family Desulfovibrionaceae, order Desulfovibrionales, and genus Candidatus Soleaferrea increased the risk of delirium, whereas the Oxalobacteraceae family, and the genera Holdemania, Ruminococcus gnavus, and Eggerthella decreased the risk of delirium. However, the potential of gut probiotic interventions in the prevention of perioperative delirium should be emphasized.

PMID

PMID:36842654

Keywords

Humans, *Gastrointestinal Microbiome/genetics, Mendelian Randomization, Analysis, Causality, *Delirium/epidemiology/genetics, Genome-Wide Association Study, Causal correlation, Delirium, Gut microbiota, Large scale analysis, Mendelian randomization

Page(s)
64-71
Issue

Search:
Total Records Found: 6050, showing 100 per page
TitleAuthorsJournalYearKeywords
Association between delirium in the intensive care unit and subsequent neuropsychiatric disorders Brown, K. N. Soo, A. Faris, P. Patten, S. B. Fiest, K. M. Stelfox, H. T. Crit Care 2020

Aged
Alberta/epidemiology
Delirium/epidemiology/ therapy
Female
Humans
Incidence
Intensive Care Units
Male
Middle Aged
Neurocognitive Disorders/ epidemiology
Odds Ratio
Retrospective Studies
Adult
Cognition disorders
Cohort studies
Critical care
Mental health

Association of Positive Delirium Screening with Incident Dementia in Skilled Nursing Facilities Briesacher, B. A. Koethe, B. Olivieri-Mui, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. J Am Geriatr Soc 2020

delirium
dementia
skilled nursing facilities

Economic Burden of Postoperative Neurocognitive Disorders Among US Medicare Patients Boone, M. D. Sites, B. von Recklinghausen, F. M. Mueller, A. Taenzer, A. H. Shaefi, S. JAMA Netw Open 2020

Aged
Cost of Illness
Female
Hospitalization/statistics & numerical data
Humans
Male
Medicare/economics
Needs Assessment
Neurocognitive Disorders/diagnosis/economics/epidemiology/etiology
Postoperative Cognitive Complications/economics/epidemiology/etiology
Quality Improvement
Surgical Procedures, Operative/ adverse effects/statistics & numerical data
United States/epidemiology

Hospital Elder Life Program in Long-Term Care (HELP-LTC): A Cluster Randomized Controlled Trial Boockvar, K. S. Judon, K. M. Eimicke, J. P. Teresi, J. A. Inouye, S. K. J Am Geriatr Soc 2020

delirium
intervention
nursing homes
randomized controlled trial

Pain Incidence, Treatment, and Associated Symptoms in Hospitalized Persons with Dementia Boltz, M. Resnick, B. Kuzmik, A. Mogle, J. Jones, J. R. Arendacs, R. BeLue, R. Cacchione, P. Galvin, J. E. Pain Manag Nurs 2020
Disparities in Physical and Psychological Symptoms in Hospitalized African American and White Persons with Dementia Boltz, M. BeLue, R. Resnick, B. Kuzmik, A. Galik, E. Jones, J. R. Arendacs, R. Sinvani, L. Mogle, J. Galvin, J. E. J Aging Health 2020

African Americans
dementia
disparities
hospitalization
race

The prevalence rates and adversities of delirium: Too common and disadvantageous Boettger, S. Zipser, C. M. Bode, L. Spiller, T. Deuel, J. Osterhoff, G. Ernst, J. Petry, H. Volbracht, J. von Känel, R. Palliat Support Care 2020

Delirium
Impact of delirium
Prevalence rate
Underdiagnosis

Assessing delirium with nursing care instruments: Evaluation of the cognitive and associated domains Bode, L. Fuchs, S. Gehrke, S. Ernst, J. Schubert, M. Nuñez, D. G. von Känel, R. Boettger, S. Palliat Support Care 2020

Assessment
Cognitive domains
Delirium
Electronic Patient Assessment — Acute Care (ePA-AC)
Nursing

Iranian Nurses Perception and Practices for Delirium Assessment in Intensive Care Units Biyabanaki, F. Arab, M. Dehghan, M. Indian J Crit Care Med 2020

Assessment
Barriers
Delirium
Intensive care unit
Nurses
Perception
Practices

How to fight against overtreatment? Example of neuroleptic prescriptions for acute delirium Bianchi, C. Blondet, F. Aebischer, O. Méan, M. Revue Medicale Suisse 2020

neuroleptic agent
article
clinical practice
delirium
health care planning
internal medicine
practice guideline
prescription

Clinical Presentation of COVID19 in Dementia Patients Bianchetti, A. Rozzini, R. Guerini, F. Boffelli, S. Ranieri, P. Minelli, G. Bianchetti, L. Trabucchi, M. Journal of Nutrition, Health and Aging 2020

aged
article
behavior disorder
clinical feature
controlled study
coronavirus disease 2019
coughing
delirium
dementia
dyspnea
female
fever
functional status
hospitalization
human
major clinical study
male
mortality rate
mortality risk
prevalence
priority journal
retrospective study
risk factor
symptomatology

Validation of two nurse-based screening tools for delirium in elderly patients in general medical wards Bergjan, M. Zilezinski, M. Schwalbach, T. Franke, C. Erdur, H. Audebert, H. J. Hauß, A. BMC Nurs 2020

Confusion
Delirium
Delirium observation screening Scale
Nursing delirium screening Scale
Risk factor
Screening

Prevalence and management of delirium in intensive care units in the Netherlands: An observational multicentre study Berger, E. Wils, E. J. Vos, P. van Santen, S. Koets, J. Slooter, A. J. C. van der Woude, M. Koopmans, M. Rinket, M. A. Hoiting, O. Hoogendoorn, E. E. Streefkerk, J. O. de Vreede, E. W. Riekerk, B. Simons, K. S. Toscano, E. Schoonderbeek, F. J. Hofstra, L. Intensive Crit Care Nurs 2020

Critically ill
Delirium management
Icu
Prevalence
Risk factors

Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial Bellapart, J. Appadurai, V. Lassig-Smith, M. Stuart, J. Zappala, C. Boots, R. Crit Care Res Pract 2020
Delirium, functional decline and quality of life after transcatheter aortic valve implantation: An explorative study Beishuizen, S. J. Festen, S. Loonstra, Y. E. van der Werf, H. W. de Rooij, S. E. van Munster, B. C. Geriatr Gerontol Int 2020

activities of daily living
cardiovascular surgery
delirium
quality of life
transcatheter aortic valve implantation

Clinical outcomes in patients admitted to hospital with cervical spine fractures or with hip fractures Baxter, J. Lisk, R. Osmani, A. Yeong, K. Robin, J. Fluck, D. Fry, C. H. Han, T. S. Intern Emerg Med 2020

Discharge destination
Geriatrics
Length of stay
Mortality
Pressure ulcers

Frequency and Implications of Complications in the ICU After Status Epilepticus: No Calm After the Storm Baumann, S. M. Semmlack, S. De Marchis, G. M. Hunziker, S. Rüegg, S. Marsch, S. Sutter, R. Critical care medicine 2020

adult
article
artificial ventilation
awareness
complication
consciousness
controlled study
delirium
epileptic state
female
hospital infection
hospitalization
human
hypotension
major clinical study
male
medical record
nervous system function
outcome assessment
prediction
retrospective study
risk assessment
risk factor

Neurological Complications and Noninvasive Multimodal Neuromonitoring in Critically Ill Mechanically Ventilated COVID-19 Patients Battaglini, D. Santori, G. Chandraptham, K. Iannuzzi, F. Bastianello, M. Tarantino, F. Ball, L. Giacobbe, D. R. Vena, A. Bassetti, M. Inglese, M. Uccelli, A. Rocco, P. R. M. Patroniti, N. Brunetti, I. Pelosi, P. Robba, C. Front Neurol 2020

Covid-19
SARS-CoV-2
neurocritical care
neurological complications
neuromonitoring

Association between plasma tau and postoperative delirium incidence and severity: a prospective observational study Ballweg, T. White, M. Parker, M. Casey, C. Bo, A. Farahbakhsh, Z. Kayser, A. Blair, A. Lindroth, H. Pearce, R. A. Blennow, K. Zetterberg, H. Lennertz, R. Sanders, R. D. Br J Anaesth 2020

biomarker
delirium
glial fibrillary acidic protein
inflammation
neuronal injury
postoperative
surgery
tau

Neurocovid: Pharmacological Recommendations for Delirium Associated With COVID-19 Baller, E. B. Hogan, C. S. Fusunyan, M. A. Ivkovic, A. Luccarelli, J. W. Madva, E. Nisavic, M. Praschan, N. Quijije, N. V. Beach, S. R. Smith, F. A. Psychosomatics 2020

Adrenergic alpha-2 Receptor Agonists/ therapeutic use
Antipsychotic Agents/ therapeutic use
Betacoronavirus
Brain Diseases/ physiopathology/psychology
Covid-19
Central Nervous System Depressants/therapeutic use
Coronavirus Infections/ physiopathology/psychology
Delirium/ drug therapy/physiopathology/psychology
Dopamine Agonists/ therapeutic use
GABA Modulators/therapeutic use
Humans
Lorazepam/therapeutic use
Melatonin/therapeutic use
Pandemics
Pneumonia, Viral/ physiopathology/psychology
Practice Guidelines as Topic
SARS-CoV-2
consultation-liaison psychiatry
coronavirus
delirium
neuropsychiatry
psychopharmacology

An Implementation Assessment of the Virtual Acute Care for Elders Program From the Perspective of Key Stakeholders Balentine, C. J. Morris, M. Knight, S. J. Turan, J. M. Flood, K. L. Gutierrez-Meza, D. Macdonald, C. L. Bhatia, S. Brown, C. J. Ann Surg 2020
The 'third wave': impending cognitive and functional decline in COVID-19 survivors Baker, H. A. Safavynia, S. A. Evered, L. A. Br J Anaesth 2020

Covid-19
delirium
frailty
hypoxaemia
neurocognitive dysfunction
neuroinflammation

Presence of urinary symptoms in bacteremic urinary tract infection: a retrospective cohort study of Escherichia coli bacteremia Bai, A. D. Bonares, M. J. Thrall, S. Bell, C. M. Morris, A. M. BMC Infect Dis 2020

Aged
Aged, 80 and over
Anti-Bacterial Agents/therapeutic use
Bacteremia/drug therapy/ epidemiology/ physiopathology
Community-Acquired Infections/drug therapy/epidemiology/microbiology/physiopathology
Escherichia coli/ isolation & purification
Escherichia coli Infections/drug therapy/ epidemiology/microbiology/ physiopathology
Female
Humans
Length of Stay
Logistic Models
Male
Middle Aged
Ontario/epidemiology
Retrospective Studies
Risk Factors
Treatment Outcome
Urinary Tract Infections/drug therapy/ epidemiology/microbiology/ physiopathology
Bacteremia
Diagnosis
Escherichia coli
Urinary tract infection

Risk Factors of Postoperative Delirium in Older Adult Spine Surgery Patients: A Meta-Analysis Baek, W. Kim, Y. M. Lee, H. AORN J 2020

delirium
older adults
postoperative complication
risk factors
spine surgery

Psychosocial volunteer support for older adults with cognitive impairment: development of MyCare Ageing using a codesign approach via action research Ayton, D. O'Donnell, R. Vicary, D. Bateman, C. Moran, C. Srikanth, V. K. Lustig, J. Banaszak-Holl, J. Hunter, P. Pritchard, E. Morris, H. Savaglio, M. Parikh, S. Skouteris, H. BMJ Open 2020

dementia
health services administration & management
quality in health care

The Volunteer Dementia and Delirium Care (VDDC)©: A pre-implementation study exploring perceived acceptability to implementing the program in an acute and subacute metropolitan hospital Ayton, D. Moran, C. Berkovic, D. Bateman, C. Anderson, K. Blair, A. Soh, S. E. Morello, R. Lim, Y. Y. Liew, D. Australas J Ageing 2020

delirium
dementia
hospital
volunteers

A call to action for delirium research: Meta-analysis and regression of delirium associated mortality Aung Thein, M. Z. Pereira, J. V. Nitchingham, A. Caplan, G. A. BMC Geriatr 2020

Aged
Delirium/diagnosis
Humans
Acute confusion
Death
Delirium
Mortality
Prognosis

Accuracy and Feasibility of Clinically Applied Frailty Instruments before Surgery: A Systematic Review and Meta-analysis Aucoin, S. D. Hao, M. Sohi, R. Shaw, J. Bentov, I. Walker, D. McIsaac, D. I. Anesthesiology 2020

Aged
Aged, 80 and over
Emergence Delirium/diagnosis
Frail Elderly
Frailty/ diagnosis
Geriatric Assessment
Hospital Mortality
Humans
Middle Aged
Postoperative Complications/ diagnosis/epidemiology/mortality
Predictive Value of Tests
Preoperative Care/ methods
Reproducibility of Results

Could COVID delirium bring on dementia? Arnold, C. Nature 2020

COVID-19/ complications/epidemiology/ psychology
Cognitive Dysfunction/epidemiology/ etiology
Critical Illness/epidemiology/psychology
Delirium/ complications/epidemiology/ psychology
Dementia/epidemiology/ etiology
Dexmedetomidine/therapeutic use
Follow-Up Studies
Humans
Medical research
Neuroscience
SARS-CoV-2

Neighborhood-Level Social Disadvantage and Risk of Delirium Following Major Surgery Arias, F. Chen, F. Fong, T. G. Shiff, H. Alegria, M. Marcantonio, E. R. Gou, Y. Jones, R. N. Travison, T. G. Schmitt, E. M. Kind, A. J. H. Inouye, S. K. J Am Geriatr Soc 2020

Area Deprivation Index
clinical outcomes in hospitalization
delirium
delirium severity
social determinants of health

Delirium is independently associated with early mortality in elderly patients starting hemodialysis Arai, Y. Shioji, S. Tanaka, H. Kondo, I. Sakamoto, E. Suzuki, M. Katagiri, D. Tada, M. Hinoshita, F. Clin Exp Nephrol 2020

Chronic kidney disease
Delirium
End-stage renal disease
Hemodialysis
Mortality

COVID-19 inpatients with psychiatric disorders: Real-world clinical recommendations from an expert team in consultation-liaison psychiatry Anmella, G. Arbelo, N. Fico, G. Murru, A. Llach, C. D. Madero, S. Gomes-da-Costa, S. Imaz, M. L. López-Pelayo, H. Vieta, E. Pintor, L. J Affect Disord 2020

Aged
Anti-Anxiety Agents/therapeutic use
Antidepressive Agents/therapeutic use
Antipsychotic Agents/therapeutic use
Betacoronavirus
Covid-19
Coronavirus Infections/ complications/psychology
Female
Humans
Inpatients/ psychology
Male
Mental Disorders/ complications/psychology/ therapy
Middle Aged
Pandemics
Pneumonia, Viral/ complications/psychology
Psychiatry
Referral and Consultation
SARS-CoV-2
Consultation liaison psychiatry
Interactions
Psychodrug
Psychopharmacology

Relationship Between Intensive Care Unit Delirium Severity and 2-Year Mortality and Health Care Utilization Andrews, P. S. Wang, S. Perkins, A. J. Gao, S. Khan, S. Lindroth, H. Boustani, M. Khan, B. American journal of critical care : an official publication, American Association of Critical-Care Nurses 2020

adult
APACHE
article
Charlson Comorbidity Index
coma
controlled study
delirium
emergency ward
female
health care utilization
hospital readmission
human
intensive care unit
major clinical study
male
mortality risk
race
randomization
randomized controlled trial
Richmond Agitation Sedation Scale

Impact of a Pharmacist-Led Intensive Care Unit Sleep Improvement Protocol on Sleep Duration and Quality Andrews, J. L. Louzon, P. R. Torres, X. Pyles, E. Ali, M. H. Du, Y. Devlin, J. W. Ann Pharmacother 2020

activity tracker
complementary therapies
intensive care
pharmaceutical services
pharmacist
quality improvement
sleep
sleep quality

A Case of Concurrent Delirium and Catatonia in a Woman With Coronavirus Disease 2019 Amouri, J. Andrews, P. S. Heckers, S. Ely, E. W. Wilson, J. E. Psychosomatics 2020
Delirium pathway: a North Hampshire experience Al-Rawi, Y. A. Progress in Neurology and Psychiatry 2020

aged
article
attitude to health
caregiver
clinical article
cognitive defect
daily life activity
delirium
dementia
elderly care
female
frailty
human
length of stay
male
mental health service
Mini Mental State Examination
Montreal cognitive assessment
New Hampshire
Parkinson disease
priority journal
residential care
social worker
very elderly

Incidence and risk factors for acute delirium in older patients with a hip fracture: A retrospective cohort study Aldwikat, R. K. Manias, E. Nicholson, P. Nurs Health Sci 2020

hip fracture
incidence
postoperative delirium
risk factors

Delirium, insulin-like growth factor I, growth hormone in older inpatients Adamis, D. Coada, I. Eikelenboom, P. Chu, C. S. Finn, K. Melvin, V. Williams, J. Meagher, D. J. McCarthy, G. World J Psychiatry 2020

Cognition
Delirium
Growth hormone
Insulin-like growth factor-I
Old age psychiatry
Older people
Pathophysiology
Physical illness

Critical Review and Meta-Analysis of Postoperative Sedation after Adult Cardiac Surgery: Dexmedetomidine Versus Propofol Abowali, H. A. Paganini, M. Enten, G. Elbadawi, A. Camporesi, E. M. J Cardiothorac Vasc Anesth 2020

adult open cardiac surgery
dexmedetomidine
postoperative sedation
propofol

Polypharmacy at admission prolongs length of hospitalization in gastrointestinal surgery patients Abe, N. Kakamu, T. Kumagai, T. Hidaka, T. Masuishi, Y. Endo, S. Kasuga, H. Fukushima, T. Geriatr Gerontol Int 2020

Adult
Aged
Aged, 80 and over
Critical Pathways
Digestive System Surgical Procedures
Female
Hospitalization
Hospitals, University
Humans
Japan
Length of Stay/ statistics & numerical data
Logistic Models
Male
Middle Aged
Polypharmacy
Retrospective Studies
clinical pathway
elderly people
gastrointestinal surgery
prolonged hospitalization

Stroke-related delirium Al-Khaled, M. Journal of the Neurological Sciences 2021

article
cerebrovascular accident
delirium
human

Practice Variability in Screening and Treating Pediatric Critical Illness Delirium: Survey Aljabari, S. Carter, C. Waheed, S. Anderson, J. E. Journal of Pediatric Intensive Care 2020

child
critical illness
delirium
drug therapy
human
intensive care unit
review
United States
university hospital
quetiapine

Perioperative complications of pediatric otorhinolaryngological operations Aleksandrovich, Y. Rybianov, V. Pshenisnov, K. V. Razumov, S. Saudi Journal of Anaesthesia 2020

Complications

ENT

Heart rate variability

Pediatric

Perioperative

Prevention as Intervention: Reducing Incident Delirium in Heart Failure Albert, B. L. Journal of doctoral nursing practice 2019

acute heart failure
adult
article
controlled study
delirium
drug safety
education
human
nurse
nursing knowledge
prevention
quality of nursing care

The prevalence of prescribing medications associated with geriatric syndromes among discharged elderly patients Akkawi, M. E. Taufek, N. H. M. Hadi, A. D. A. Nik Lah, N. N. N. F. Journal of Pharmacy and Bioallied Sciences 2020

Elderly patients

Geriatric Syndromes

Medication prescribing

Incidence and predictors of delirium after cardiac arrest – A retrospective registry Aicher, N. Jäckel, M. Faye, C. Wengenmayer, T. Bode, C. Staudacher, D. L. Resuscitation 2020

noradrenalin
aged
complication
conference abstract
controlled study
delirium
extubation
female
heart arrest
human
incidence
induced hypothermia
invasive ventilation
linear regression analysis
major clinical study
male
medical intensive care unit
nurse
professional standard
resuscitation
retrospective study
rhythm
risk factor

Is ketamine safe for the pre-hospital sedation of patients with excited delirium secondary to sympathomimetic toxicity? Adams, Y. Australasian Journal of Paramedicine 2019

adrenergic receptor stimulating agent
ketamine
adult
adverse drug reaction
ambulance
Cinahl
cohort analysis
conference abstract
delirium
drug safety
drug therapy
evidence based medicine
female
human
male
Medline
New Zealand
pharmacokinetics
retrospective study
Scopus
sedation
side effect
systematic review

Prospective, multi-centric benchmark study assessing delirium: prevalence, incidence and its correlates in hospitalized elderly Lebanese patients Zrour, C. Haddad, R. Zoghbi, M. Kharsa, Z. Hijazi, M. Naja, W. Aging Clin Exp Res 2020

Correlated factors
Delirium
Hospitalized elderly patients
Incidence
Overall prevalence

Knowledge and attitudes of adolescents with psychiatric disorders and their caregivers towards electroconvulsive therapy in China Zong, Q. Q. Qi, H. Wang, Y. Y. Zhang, C. Balbuena, L. Ungvari, G. S. An, F. R. Xiang, Y. T. Asian Journal of Psychiatry 2020

adolescent
adolescent disease
adverse outcome
article
caregiver
China
confusion
controlled study
critically ill patient
cross-sectional study
electroconvulsive therapy
female
headache
human
major clinical study
male
memory disorder
mental disease
patient attitude
priority journal
risk factor
therapy effect

Does postoperative delirium following elective noncardiac surgery predict long-term mortality? Ziman, N. Sands, L. P. Tang, C. Zhu, J. Leung, J. M. Age Ageing 2020

long-term mortality
older people
postoperative delirium
prospective studies
surgery

Anxiety administrated by dexmedetomidine to prevent new-onset of postoperative atrial fibrillation in patients undergoing off-pump coronary artery bypass graft Zi, J. Fan, Y. Dong, C. Zhao, Y. Li, D. Tan, Q. International Heart Journal 2020

1800014314
C reactive protein
calcium channel blocking agent
dexmedetomidine
dopamine
epinephrine
fentanyl
hydroxymethylglutaryl coenzyme A reductase inhibitor
metoprolol
propofol
sufentanil
vecuronium
adult
anxiety
aortic pressure
artery catheterization
article
artificial ventilation
atrial fibrillation
bradycardia
brain infarction
chronic obstructive lung disease
clinical feature
clinical trial
controlled study
delirium
double blind procedure
drug efficacy
electrocardiography
endotracheal intubation
female
heart left ventricle ejection fraction
human
hypotension
incidence
infusion rate
intensive care unit
ischemic heart disease
lung pressure
major clinical study
male
middle aged
off pump coronary surgery
outcome assessment
priority journal
prospective study
psychologic assessment
randomized controlled trial
respiration depression
risk factor
sedation
Self-rating Anxiety Scale
sternotomy
surgical technique
transthoracic echocardiography

Assessment of Melatonergics in Prevention of Delirium: A Systematic Review and Meta-Analysis Zhu, Y. Jiang, Z. Huang, H. Li, W. Ren, C. Yao, R. Wang, Y. Yao, Y. Li, W. Du, B. Xi, X. Front Neurol 2020

critical care medicine
delirium
melatonin
prevention
systematic review

Geriatric Nutritional Risk Index can predict postoperative delirium and hospital length of stay in elderly patients undergoing non-cardiac surgery Zhao, Y. Xia, X. Xie, D. Liao, Y. Wang, Y. Chen, L. Ge, N. Yue, J. Geriatr Gerontol Int 2020

Geriatric Nutritional Risk Index
elderly
length of stay
postoperative delirium

The geriatric nutrition risk index versus the mini-nutritional assessment short form in predicting postoperative delirium and hospital length of stay among older non-cardiac surgical patients: a prospective cohort study Zhao, Y. Ge, N. Xie, D. Gao, L. Wang, Y. Liao, Y. Yue, J. BMC Geriatr 2020

Geriatric nutritional risk index
Length of stay
Mini-nutritional assessment short form
Non-cardiac surgery
Older people
Postoperative delirium

Perioperative Multicomponent Interdisciplinary Program Reduces Delirium Incidence in Elderly Patients With Hip Fracture Zhao, X. Yuan, W. J Am Psychiatr Nurses Assoc 2020

delirium
hip fracture
multicomponent
nurse
prevention

Emergence delirium is associated with increased postoperative delirium in elderly: a prospective observational study Zhang, Y. He, S. T. Nie, B. Li, X. Y. Wang, D. X. J Anesth 2020

Elderly
Emergence delirium
General anesthesia
Major surgery
Postoperative delirium

S100β as a potential biomarker of incident delirium: a systematic review and meta-analysis Zhang, X. Lyu, Y. Wang, D. Minerva Anestesiol 2020
Effects of Dexmedetomidine on Postoperative Delirium and Expression of IL-1β, IL-6, and TNF-α in Elderly Patients After Hip Fracture Operation Zhang, W. Wang, T. Wang, G. Yang, M. Zhou, Y. Yuan, Y. Front Pharmacol 2020

dexmedetomidine
elderly patients
hip fracture
postoperative delirium
pro-inflammatory factor

Nomogram Model for Predicting Risk of Postoperative Delirium After Deep Brain Stimulation Surgery in Patients Older Than 50 Years with Parkinson Disease Zhan, L. Wang, X. Q. Zhang, L. X. World Neurosurg 2020

Advanced age
Deep brain stimulation
Nomogram
Parkinson disease
Postoperative delirium
Risk factor

Combining Ultrafast Anaesthesia and Minimal Invasive Implantation in HeartMate 3: A Pilot Study Zayat, R. Ahmad, U. Twarie, L. Moza, A. Schaelte, G. Allham, O. Haneya, A. Khattab, M. Schnoering, H. Autschbach, R. The Journal of heart and lung transplantation 2020

adult
anesthesia
article
artificial ventilation
bleeding
cardiac index
central venous pressure
clinical article
complication
controlled study
delirium
extubation
female
heart right ventricle failure
human
implantation
incidence
intermethod comparison
left ventricular assist device
male
middle aged
multicenter study
outcome assessment
pilot study
pneumonia
postoperative complication
postoperative period
pulmonary artery occlusion pressure
pulse wave
reoperation
sternotomy
surgery
thoracotomy
inotropic agent

Exosome α-Synuclein Release in Plasma May be Associated With Postoperative Delirium in Hip Fracture Patients Yuan, Y. Li, Z. Yang, N. Han, Y. Ji, X. Han, D. Wang, X. Li, Y. Liu, T. Yuan, F. He, J. Liu, Y. Ni, C. Zou, P. Wang, G. Guo, X. Zhou, Y. Front Aging Neurosci 2020

exosome
geriatric (aging)
hip fracture
postoperative delirium
α-synuclein

A multicentre, pragmatic, cluster randomised, controlled feasibility trial of the POD system of care Young, J. Green, J. Farrin, A. Collinson, M. Hartley, S. Smith, J. Teale, E. Siddiqi, N. Inouye, S. K. Age Ageing 2020

delirium
hospitals
multicomponent interventions
older people
prevention

Association of Reversal of Anticoagulation Preoperatively on 30-Day Mortality and Outcomes for Hip Fracture Surgery Yoo, M. S. Zhu, S. Jiang, S. F. Hammer, H. L. McBride, W. J. McCarthy, C. M. Green, C. E. Ananias, M. P. American Journal of Medicine 2020

adult
aged
anticoagulation
article
California
controlled study
delirium
drug therapy
hip fracture
human
international normalized ratio
length of stay
male
mortality
multicenter study (topic)
perioperative medicine
preoperative evaluation
surgery
systematic review
warfarin

Perioperative Complications and Prognosis of Curative Surgical Resection for Spinal Metastases in Elderly Patients Yonezawa, N. Murakami, H. Demura, S. Kato, S. Yoshioka, K. Shinmura, K. Yokogawa, N. Shimizu, T. Oku, N. Kitagawa, R. Handa, M. Annen, R. Kurokawa, Y. Tsuchiya, H. World Neurosurgery 2020

titanium cage
liquid nitrogen
tranexamic acid
adult
aged
aged hospital patient
article
autograft
bladder cancer
breast cancer
cancer of unknown primary site
cancer prognosis
cancer recurrence
cerebellum hemorrhage
cervical spine
chondrosarcoma
chylothorax
computer assisted tomography
corpectomy
deep vein thrombosis
distant metastasis
female
follow up
Frankel grade
functional status
hemivertebrectomy
human
Kaplan Meier method
leiomyosarcoma
liquorrhea
lung embolism
major clinical study
male
middle aged
neurological complication
osteosarcoma
overall survival
peroperative complication
pleura effusion
pneumocephalus
pneumothorax
postoperative complication
postoperative delirium
preoperative evaluation
renal cell carcinoma
reoperation
retrospective study
sarcoma
spinal cord infarction
spinal cord ischemia
spine metastasis
spine radiography
spine surgery
subdural hematoma
surgical approach
surgical infection
surgical technique
survival analysis
survival rate
thoracolumbar spine
thyroid cancer
total en bloc spondylectomy
vertebra body
walking
wound dehiscence

Risk factors for delirium in intensive care unit and its duration Yanyan, L. Dajiang, Y. Xiaoya, L. Shao, W. Zhonghua Wei Zhong Bing Ji Jiu Yi Xue 2020

sedative agent
APACHE
article
artificial ventilation
disease duration
drug use
female
general anesthesia
human
hypoxia
incidence
intensive care psychosis
intensive care unit
length of stay
major clinical study
male
risk factor
screening
sex difference
spinal anesthesia
treatment duration

Melatonergic agents in the prevention of delirium: A network meta-analysis of randomized controlled trials Yang, C. P. Tseng, P. T. Pei-Chen Chang, J. Su, H. Satyanarayanan, S. K. Su, K. P. Sleep Med Rev 2020

Delirium
Melatonin
Melatonin agonist
Prevention
Ramelteon

Oxycodone preemptive analgesia after endoscopic plasma total adenotonsillectomy in children a randomized controlled trial Wu, J. Gui, Q. Wang, J. Ye, J. Xia, Z. Wang, S. Liu, F. Kong, F. Zhong, L. Medicine (United States) 2020

ChiCTR-INR-16009116
BCDB-100 electronic analgesia pump
Datex-Ohmeda S/5 monitor
monitor
pump
atropine
cisatracurium
hetastarch
messenger RNA
oxycodone
oxygen
propofol
protein c fos
remifentanil
sufentanil
adenotonsillar hypertrophy
adenotonsillectomy
analgesia
analgesic activity
article
child
continuous infusion
controlled study
drug efficacy
electroencephalogram
endoscopic plasma total adenotonsillectomy
endoscopic surgery
extubation
Face Legs Activity Cry and Consolability score
female
follow up
human
major clinical study
male
nausea
operation duration
outcome assessment
pediatric anesthesia
Pediatric Anesthesia Emergence Delirium score
postoperative analgesia
postoperative pain
postoperative period
prediction
preemptive analgesia
preschool child
priority journal
probability
protein blood level
quantitative analysis
randomized controlled trial
real time polymerase chain reaction
response entropy
scoring system
sleep disordered breathing
stress

Delirium screening practice in specialist palliative care units: a survey Woodhouse, R. Siddiqi, N. Boland, J. W. Featherstone, I. Johnson, M. J. BMJ Support Palliat Care 2020

delirium
hospice care
terminal care

Movements and trends in intensive care pain treatment and sedation: What matters to the patient? Wøien, H. J Clin Nurs 2020

Adult
Aged
Critical Care/ methods
Delirium/prevention & control
Female
Guideline Adherence
Humans
Hypnotics and Sedatives/administration & dosage/ adverse effects
Longitudinal Studies
Male
Middle Aged
Pain/drug therapy
Pain Management/ methods
Prospective Studies
Respiration, Artificial/methods
analgosedation
critically ill
delirium
implementation
intensive care
pain
sedation

Quetiapine therapy in critically injured trauma patients is associated with an increased risk of pulmonary complications Wessels, L. E. Wallace, J. D. Calvo, R. Y. Levko, T. Bowie, J. M. Butler, W. J. Bansal, V. Sise, C. B. Martin, M. J. Sise, M. J. Am J Surg 2020

Antipsychotic Agents/ adverse effects
Critical Illness
Delirium/ drug therapy/ etiology
Female
Humans
Intensive Care Units
Lung Diseases/ chemically induced
Male
Middle Aged
Quetiapine Fumarate/ adverse effects
Retrospective Studies
Risk Factors
Trauma Centers
Wounds and Injuries/ complications
Delirium
Pulmonary complications
Quetiapine
Sedation
Trauma

Combined non-intubated anaesthesia and paravertebral nerve block in comparison with intubated anaesthesia in children undergoing video-assisted thoracic surgery Wei, W. Fan, Y. Liu, W. Zhao, T. Tian, H. Xu, Y. Tan, Y. Song, X. Ma, D. Acta Anaesthesiol Scand 2020
The occurrence and timing of delirium in acute care hospitalizations in the last year of life: A population-based retrospective cohort study Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Talarico, R. Tanuseputro, P. Palliat Med 2020

Delirium
hospitalization
prevalence
retrospective studies
risk factors
terminal care

Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach? Warnier, R. M. J. van Rossum, E. van Kuijk, S. M. J. Magdelijns, F. Schols, Jmga Kempen, Gijm J Clin Nurs 2020

Aged
Aged, 80 and over
Female
Frailty/ diagnosis/mortality
Geriatric Assessment/ methods
Humans
Male
Mass Screening/ methods
Patient Readmission/statistics & numerical data
Predictive Value of Tests
ROC Curve
Retrospective Studies
Risk Assessment/methods
feasibility
frailty
frailty screening
geriatric assessment
hospitalised patients
nursing assessment
risk screening
safety programme
validity

Predicting postoperative delirium after microvascular decompression surgery with machine learning Wang, Y. Lei, L. Ji, M. Tong, J. Zhou, C. M. Yang, J. J. J Clin Anesth 2020

Machine learning
Microvascular decompression
Postoperative delirium

Propensity score-adjusted three-component mixture model for drug-drug interaction data mining in FDA Adverse Event Reporting System Wang, X. Li, L. Wang, L. Feng, W. Zhang, P. Statistics in Medicine 2020

amfebutamone
bevacizumab
bimatoprost
budesonide
bupivacaine
carboplatin
carvedilol
duloxetine
escitalopram
filgrastim
gemcitabine
lamotrigine
metaxalone
methamphetamine
naloxone
parathyroid hormone[1-34]
pegfilgrastim
phenytoin
prednisone
rofecoxib
rosiglitazone
rosuvastatin
telmisartan
tetracycline
unindexed drug
valdecoxib
valproic acid
varenicline
warfarin
zoledronic acid
adverse outcome
analytic method
article
comparative study
controlled study
data analysis
data mining
delirium
disease association
drug potentiation
false positive result
human
mathematical model
neuropathy
risk factor
signal detection
simulation

Comparison between Dexmedetomidine and Midazolam for Sedation in Patients with Intubation after Oral and Maxillofacial Surgery Wang, L. Zhang, T. Huang, L. Peng, W. Biomed Res Int 2020
Comparison of Intranasal Dexmedetomidine and Oral Midazolam for Premedication in Pediatric Dental Patients under General Anesthesia: A Randomised Clinical Trial Wang, L. Huang, L. Zhang, T. Peng, W. Biomed Res Int 2020
Accelerated magnetic seizure therapy (aMST) for treatment of major depressive disorder: A pilot study Wang, J. Vila-Rodriguez, F. Ge, R. Gao, S. Gregory, E. Jiang, W. Yang, C. Wang, G. J Affect Disord 2020

Cognition
Magnetic seizure therapy
Major depressive disorder

Development and validation of the delirium risk assessment score (DRAS) Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. Eur Geriatr Med 2020

Delirium
Predisposing risk factors
Prevention
Risk assessment
Screening instrument

Development and validation of the delirium risk assessment score (DRAS) Vreeswijk, R. Kalisvaart, I. Maier, A. B. Kalisvaart, K. J. Eur Geriatr Med 2020

Delirium
Predisposing risk factors
Prevention
Risk assessment
Screening instrument

Hospital readmission following transjugular intrahepatic portosystemic shunt: A 14-year single-center experience Vozzo, C. F. Singh, T. Bullen, J. Sarvepalli, S. McCullough, A. Kapoor, B. Gastroenterology Report 2020

politef implant
stent graft
TIPS endoprosthesis
lactulose
politef
rifaximin
abdominal pain
abdominal wall hernia
adult
alcohol liver disease
article
ascites
clinical outcome
combination drug therapy
confusion
controlled study
electronic medical record
female
hepatic encephalopathy
hospital readmission
human
hypervolemia
longitudinal study
major clinical study
male
medical record review
middle aged
Model For End Stage Liver Disease Score
nonalcoholic steatohepatitis
pancreatitis
postoperative hemorrhage
postoperative infection
postoperative nausea and vomiting
postoperative pain
priority journal
retrospective study
transjugular intrahepatic portosystemic shunt

Anticholinergic drug exposure at intensive care unit admission affects the occurrence of delirium. A prospective cohort study Vondeling, A. M. Knol, W. Egberts, T. C. G. Slooter, A. J. C. Eur J Intern Med 2020

Anticholinergics
Cohort studies
Critical care
Delirium
Intensive care
Survival analysis

Delirium Screening in Neurocritical Care and Stroke Unit Patients: A Pilot Study on the Influence of Neurological Deficits on CAM-ICU and ICDSC Outcome von Hofen-Hohloch, J. Awissus, C. Fischer, M. M. Michalski, D. Rumpf, J. J. Classen, J. Neurocrit Care 2020

Cam-icu
Delirium
Icdsc
Neurocritical care
Stroke

Intensive Care Unit Delirium in Surgical Patients Is Associated with Upregulation in Tryptophan Metabolism Voils, S. A. Shoulders, B. R. Singh, S. Solberg, L. M. Garrett, T. J. Frye, R. F. Pharmacotherapy 2020

critical care
delirium
metabolomics
surgery

Vitamin D and Postoperative Delirium After Coronary Artery Bypass Grafting: A Prospective Cohort Study Velayati, A. Vahdat Shariatpanahi, M. Dehghan, S. Zayeri, F. Vahdat Shariatpanahi, Z. Journal of Cardiothoracic and Vascular Anesthesia 2020

adult
article
cardiopulmonary bypass
cohort analysis
controlled study
coronary artery bypass surgery
female
human
human tissue
intensive care unit
major clinical study
male
postoperative delirium
prospective study
risk factor
surgery
university hospital
vitamin D deficiency
vitamin D

New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study Vasunilashorn, S. M. Schulman-Green, D. Tommet, D. Fong, T. G. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Helfand, B. Inouye, S. K. Jones, R. N. Dement Geriatr Cogn Disord 2020

Delirium
Delirium severity
Psychometrics

A New Severity Scoring Scale for the 3-Minute Confusion Assessment Method (3D-CAM) Vasunilashorn, S. M. Devinney, M. J. Acker, L. Jung, Y. Ngo, L. Cooter, M. Huang, R. Marcantonio, E. R. Berger, M. J Am Geriatr Soc 2020
Use of a digital delirium pathway and quality improvement to improve delirium detection in the emergency department and outcomes in an acute hospital Vardy, E. Collins, N. Grover, U. Thompson, R. Bagnall, A. Clarke, G. Heywood, S. Thompson, B. Wintle, L. Nutt, L. Hulme, S. Age Ageing 2020

acute
delirium
digital
electronic health record
older people
quality improvement

Registration of attentional function as a predictor of incident delirium (the RAPID study) van Zuylen, M. L. Hermanides, J. Ten Hoope, W. Preckel, B. van de Beek, D. van Gool, W. A. Schoenmaker, N. Alzheimers Dement (N Y) 2020

attentional function
attentional impairments
consciousness
elective major surgery
postoperative delirium

Predisposition for delirium and EEG characteristics van Montfort, S. J. T. van Dellen, E. Wattel, L. L. Kant, I. M. J. Numan, T. Stam, C. J. Slooter, A. J. C. Clin Neurophysiol 2020

Delirium
Eeg
Functional connectivity
Functional impairment
Graph analysis
Risk factors

Geriatric assessment in the prediction of delirium and long-term survival after transcatheter aortic valve implantation van der Wulp, K. van Wely, M. H. Schoon, Y. Vart, P. Olde Rikkert, M. G. M. Morshuis, W. J. van Royen, N. Verkroost, M. W. A. Gehlmann, H. R. Van Garsse, L. A. F. M. Kievit, P. C. Journal of Thoracic and Cardiovascular Surgery 2020

aged
article
clinical assessment
controlled study
facilitation
female
frailty
geriatric assessment
geriatrician
high risk patient
hospitalization
human
long term survival
major clinical study
male
mortality
multicenter study
postoperative delirium
prediction
prospective study
risk assessment
transcatheter aortic valve implantation
very elderly

Complications with focus on delirium during hospital stay related to femoral nerve block compared to conventional pain management among patients with hip fracture – A randomised controlled trial Unneby, A. Svensson, P. O. Gustafson, P. Y. Lindgren, A. P. B. M. Bergström, U. Olofsson, P. B. Injury 2020

aged
analgesia
anemia
article
clinical trial
complication
constipation
controlled study
dementia
drug therapy
DSM-IV-TR
female
femoral nerve
geriatrics
hip fracture
hospitalization
human
incidence
major clinical study
male
nerve block
nurse
nutritional disorder
peripheral nerve
postoperative delirium
randomized controlled trial
surgery
urinary tract infection
very elderly
opiate

Preoperative Vitamin D Level is Associated with Postoperative Delirium After Cardiac Surgery in Patients Over 65 Years of Age Tumer, N. B. Tekeli Kunt, A. Gunaydin, S. Ozisik, K. Heart Surg Forum 2020
Epileptic seizure discharges in patients after open chamber cardiac surgery—a prospective prevalence pilot study using continuous electroencephalography Tschernatsch, M. Juenemann, M. Alhaidar, F. El Shazly, J. Butz, M. Meyer, M. Gerriets, T. Schönburg, M. Schramm, P. Intensive Care Medicine 2020

adult
anesthesia
article
cardiac surgery intensive care unit
controlled study
delirium
electroencephalography monitoring
female
human
incidence
major clinical study
male
neurologist
observational study
pilot study
postoperative care
prevalence
prospective study
retrospective study
seizure
single blind procedure
surgery
theta rhythm
valve

Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium Trogrlić, Z. van der Jagt, M. Osse, R. J. Devlin, J. W. Nieboer, D. Koch, B. C. P. van Schaik, R. H. N. Hunfeld, N. G. M. J Crit Care 2020

Delirium
Haloperidol
Intensive care
Pharmacodynamics
Pharmacogenetics
Pharmacokinetics

The Impact of Music and Noise-Cancellation on Sedation Requirements During Total Knee Replacement: A Randomized Controlled Trial Tran, B. W. Nowrouz, M. Y. Dhillon, S. K. Xie, K. K. Breslin, K. M. Golladay, G. J. Geriatr Orthop Surg Rehabil 2020

acute pain medicine
adult reconstructive surgery
anesthesia
geriatric medicine
music therapy
regional anesthesia

The Prevalence and Impact of Undiagnosed Mild Cognitive Impairment in Elderly Patients Undergoing Thoracic Surgery: A Prospective Cohort Study Tong, C. Huang, C. Wu, J. Xu, M. Cao, H. J Cardiothorac Vasc Anesth 2020

Mild cognitive impairment
Postoperative delirium
Postoperative pulmonary complications
Thoracic surgery

Development of a Palliative Care Toolkit for the COVID-19 Pandemic Thomas, J. D. Leiter, R. E. Abrahm, J. L. Shameklis, J. C. Kiser, S. B. Gelfand, S. L. Sciacca, K. R. Reville, B. Siegert, C. A. Zhang, H. Lai, L. Sato, R. Smith, L. N. Kamdar, M. M. Greco, L. Lee, K. A. Tulsky, J. A. Lawton, A. J. Journal of pain and symptom management 2020

adult
article
communication skill
controlled study
conversation
coronavirus disease 2019
critically ill patient
delirium
dyspnea
evidence based practice center
hospitalization
human
nurse practitioner
pain
palliative therapy
pandemic
videorecording

Interventions to Improve Clinical Outcomes in Older Adults Admitted to a Surgical Service: A Systematic Review and Meta-analysis Thillainadesan, J. Yumol, M. F. Hilmer, S. Aitken, S. J. Naganathan, V. J Am Med Dir Assoc 2020

Aging
comprehensive geriatric assessment
delirium
functional status
outcomes
surgery

Timeliness of care and adverse event profile in children undergoing general anesthesia or sedation for MRI: An observational prospective cohort study Thampi, S. Jose, R. Kothandan, P. Jiwanmall, M. Rai, E. Saudi Journal of Anaesthesia 2020

laryngeal mask
propofol
sevoflurane
adverse drug reaction
airway obstruction
anesthesia complication
anesthesia induction
anesthetic recovery
article
bradycardia
child
clinical outcome
cohort analysis
controlled study
disease re-emergence
emergence agitation
female
health care
human
inhalation anesthesia
larynx spasm
major clinical study
male
nausea
nuclear magnetic resonance imaging
observational study
oxygen desaturation
pediatric anesthesia
preschool child
priority journal
prospective study
sedation
side effect
timeliness
vomiting