Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
An Interdisciplinary Reappraisal of Delirium and Proposed Subtypes
Authors
Oldham, M. A. Slooter, A. J. C. Ely, E. W. Crone, C. Maldonado, J. R. Rosenthal, L. J.
Year
2022
Journal
J Acad Consult Liaison Psychiatry
Abstract

An interdisciplinary plenary session entitled “Rethinking and Rehashing Delirium” was held during the 2021 Annual Meeting of the Academy of Consultation-Liaison Psychiatry to facilitate dialog on the prevalent approach to delirium. Panel members included a psychiatrist, neurointensivist, and critical care specialist, and attendee comments were solicited with the goal of developing a statement. Discussion was focused on a reappraisal of delirium and, in particular, its disparate terminology and history in relation to acute encephalopathy. The authors endorse a recent joint position statement that describes acute encephalopathy as a rapidly evolving (<4 weeks) pathobiological brain process that presents as subsyndromal delirium, delirium, or coma and suggest the following points of refinement: (1) to suggest that “delirium disorder” describe the diagnostic construct including its syndrome, precipitant(s), and unique pathophysiology; (2) to restrict the term “delirium” to describing the clinical syndrome encountered at the bedside; (3) to clarify that the disfavored term “altered mental status” may occasionally be an appropriate preliminary designation where the diagnosis cannot yet be specified further; and (4) to provide rationale for rejecting the terms acute brain injury, failure, or dysfunction. The final common pathway of delirium appears to involve higher-level brain network dysfunction, but there are many insults that can disrupt functional connectivity. We propose that future delirium classification systems should seek to characterize the unique pathophysiological disturbances (“endotypes”) that underlie delirium and delirium’s individual neuropsychiatric symptoms. We provide provisional means of classification in hopes that novel subtypes might lead to specific intervention to improve patient experience and outcomes. This paper concludes by considering future directions for the field. Key areas of opportunity include interdisciplinary initiatives to harmonize efforts across specialties and settings, enhance underrepresented groups in research, integration of delirium and encephalopathy in coding, development of relevant quality and safety measures, and exploration of opportunities for translational science.

PMID

35840003

Keywords

acute encephalopathy
altered mental status
delirium disorder
neuropsychiatric symptoms
pathophysiology
subtypes

Page(s)
Issue

Search:
Total Records Found: 6300, showing 100 per page
TitleAuthorsJournalYearKeywords
Risk prediction models for emergence delirium in paediatric general anaesthesia: a systematic review Petre, M. A. Saha, B. Kasuya, S. Englesakis, M. Gai, N. Peliowski, A. Aoyama, K. BMJ Open 2021

Anesthesia, General/ adverse effects
Bias
Child
Cognition/ drug effects
Cognition Disorders/chemically induced
Emergence Delirium/ chemically induced/diagnosis
Humans
Risk Assessment
Surgical Procedures, Operative
Delirium & cognitive disorders
Paediatric anaesthesia
emergence delirium

The Effects of Propofol or Dexmedetomidine Sedation on Postoperative Recovery in Elderly Patients Receiving Lower Limb Surgery under Spinal Anesthesia: A Retrospective Propensity Score-Matched Analysis Park, J. W. Kim, E. K. Lee, H. T. Park, S. Do, S. H. J Clin Med 2021

dexmedetomidine
intraoperative sedation
postoperative delirium
propofol

High proportion of thiamine deficiency in referred cancer patients with delirium: a retrospective descriptive study Onishi, H. Sato, I. Uchida, N. Takahashi, T. Furuya, D. Ebihara, Y. Yoshioka, A. Ito, H. Ishida, M. Eur J Clin Nutr 2021
Association between discontinuation of benzodiazepine receptor agonists and post-operative delirium among inpatients with liaison intervention: A retrospective cohort study Omichi, C. Ayani, N. Oya, N. Matsumoto, Y. Tanaka, M. Morimoto, T. Kadotani, H. Narumoto, J. Compr Psychiatry 2021

Benzodiazepines/adverse effects
Delirium/chemically induced/diagnosis/epidemiology
Humans
Inpatients
Receptors, GABA-A
Retrospective Studies
benzodiazepine receptor agonist
benzodiazepine withdrawal syndrome
consultation-liaison psychiatry
discontinuation
post-operative delirium

The Independent Association of Prestroke Psychiatric Symptoms and Acute Phase Delirium with Poststroke Mortality at One Year in Nigeria Ojagbemi, A. Bello, T. Owolabi, M. Baiyewu, O. J Stroke Cerebrovasc Dis 2021

Delirium/diagnosis/ mortality/psychology
Female
Humans
Longitudinal Studies
Male
Mental Disorders/diagnosis/ mortality/psychology
Mental Health
Middle Aged
Nigeria/epidemiology
Prognosis
Prospective Studies
Risk Assessment
Risk Factors
Stroke/diagnosis/ mortality/psychology
Surveys and Questionnaires
Time Factors
Mental health complications
Neurocognitive disorders
Prestroke symptoms
Stroke burden
Sub-Saharan Africa

Depression predicts long-term cognitive impairment in survivors of critical illness Nordness, M. F. Bipin Patel, M. Erickson, C. R. Kiehl, A. Jackson, J. C. Raman, R. Pandharipande, P. P. Ely, E. W. Wilson, J. E. J Trauma Acute Care Surg 2021

Aged
Cognitive Dysfunction/ etiology
Critical Illness/ psychology
Depression/ complications/etiology
Female
Humans
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Neuropsychological Tests
Prospective Studies
Stress Disorders, Post-Traumatic/complications/etiology
Survivors/ psychology/statistics & numerical data

Effects of uncomfortable care and histamine H2-antagonists on delirium in acute stroke: A propensity score analysis Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. J Neurol Sci 2021

Delirium/epidemiology/etiology
Histamine
Histamine H2 Antagonists
Humans
Intensive Care Units
Propensity Score
Prospective Studies
Stroke/complications/drug therapy
Adverse effect
Anti-ulcer agent
Clinical nursing research
Gastrointestinal haemorrhage
Immobilization
Indwelling catheter
Prevention and control
Sleep deprivation

Family automated voice reorientation (FAVoR) intervention for mechanically ventilated patients in the intensive care unit: Study protocol for a randomized controlled trial Munro, C. L. Liang, Z. Ji, M. Elías, M. N. Chen, X. Calero, K. Ely, E. W. Contemp Clin Trials 2021

Cognition
Critical illness
Delirium
Mechanical ventilation
Randomized controlled trial
Sleep

Evaluation of a delirium awareness podcast for undergraduate nursing students in Northern Ireland: a pre-/post-test study Mitchell, G. Scott, J. Carter, G. Wilson, C. B. BMC Nurs 2021

Constructivist pedagogy
Delirium
Nurse education
Nursing student
Pedagogical research
Podcast
Quantitative research methods

Impact of delirium in acute cardiac care unit after transcatheter aortic valve replacement Luque, T. Noriega, F. J. McInerney, A. Travieso, A. Corrochano, D. Tirado-Conte, G. Ferrera, C. Fossati, S. Jimenez-Quevedo, P. Nuñez-Gil, I. Gonzalo, N. Escaned, J. Macaya, C. Fernández-Ortiz, A. Nombela-Franco, L. Viana-Tejedor, A. Int J Cardiol 2021

Aortic Valve/surgery
Aortic Valve Stenosis/surgery
Delirium/diagnosis/epidemiology/etiology
Humans
Length of Stay
Postoperative Complications/diagnosis/epidemiology
Risk Factors
Transcatheter Aortic Valve Replacement/adverse effects
Treatment Outcome
Acute cardiac care
Aortic stenosis
Delirium
Transcatheter aortic valve replacement

Preoperative Prognostic Nutritional Index Value is Related to Postoperative Delirium in Elderly Patients After Noncardiac Surgery: A Retrospective Cohort Study Liu, H. Dai, M. Guan, H. Gao, X. Zhou, Y. Sun, X. Zhou, J. Hu, X. Li, X. Song, Y. Han, Y. Cao, J. Risk Manag Healthc Policy 2021

elderly patients
noncardiac surgery
nutritional status
postoperative delirium
prognostic nutritional index

Implementation of ABCDEF care bundle in intensive care units: A cross-sectional survey Liang, S. Chau, J. P. C. Lo, S. H. S. Li, S. Gao, M. Nurs Crit Care 2021

ABCDEF care bundle
delirium
intensive care unit
registered nurses

Lymphocyte and NK Cell Counts Can Predict Sepsis-Associated Delirium in Elderly Patients Li, D. Zhang, J. Bai, G. Chen, J. Cheng, W. Cui, N. Front Aging Neurosci 2021

NK cell
delirium
elderly people
lymphocyte subsets
sepsis-associated delirium

Safety and Efficacy of Dexmedetomidine in Acutely Ill Adults Requiring Noninvasive Ventilation: A Systematic Review and Meta-analysis of Randomized Trials Lewis, K. Piticaru, J. Chaudhuri, D. Basmaji, J. Fan, E. Møller, M. H. Devlin, J. W. Alhazzani, W. Chest 2021

dexmedetomidine
noninvasive ventilation
positive pressure ventilation
respiratory failure
sedation

Pharmacological strategies to prevent postoperative delirium: a systematic review and network meta-analysis Lee, J. M. Cho, Y. J. Ahn, E. J. Choi, G. J. Kang, H. Anesth Pain Med (Seoul) 2021

Delirium
Network meta-analysis
Pharmacology
Surgical procedures

Evaluation of Melatonin Practices for Delirium in Pediatric Critically Ill Patients Laudone, T. W. Beck, S. D. Lahr, H. J. J Pediatr Pharmacol Ther 2021

antipsychotic
delirium
melatonin
pediatric intensive care unit
prophylaxis
sedation

Results from a double blinded, randomised, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B. Intern Med J 2021

Aged
Delirium/diagnosis/drug therapy
Double-Blind Method
Feasibility Studies
Humans
Inpatients
Melatonin
delirium
neurocognitive disorder
sepsis-associated encephalopathy
sleep
treatment

Delirium, Cerebral Perfusion, and High-Frequency Vital-Sign Monitoring in the Critically Ill. The CONFOCAL-2 Feasibility Study Khan, J. M. Wood, M. D. Lee, K. F. H. Maslove, D. Muscedere, J. English, S. W. Ball, I. Slessarev, M. Boyd, J. G. Ann Am Thorac Soc 2021

cerebral oxygenation
cognitive outcomes
critical illness
delirium
near-infrared spectroscopy

Preoperative brain MRI features and occurrence of postoperative delirium Kant, I. M. J. de Bresser, J. van Montfort, S. J. T. Mutsaerts, Hjmm Witkamp, T. D. Buijsrogge, M. Spies, C. Hendrikse, J. Slooter, A. J. C. J Psychosom Res 2021

Aged
Brain/ diagnostic imaging
Delirium/ etiology/pathology
Female
Humans
Magnetic Resonance Imaging/ adverse effects
Male
Preoperative Period
Prospective Studies
Cortical infarcts
Delirium
MRI markers
White matter hyperintensities

Intraoperative monitoring parameters and postoperative delirium: Results of a prospective cross-sectional trial Jung, C. Hinken, L. Fischer-Kumbruch, M. Trübenbach, D. Fielbrand, R. Schenk, I. Diegmann, O. Krauß, T. Scheinichen, D. Schultz, B. Medicine (Baltimore) 2021

Adult
Aged
Aged, 80 and over
Anesthetics, Inhalation/adverse effects/therapeutic use
Cross-Sectional Studies
Delirium/ classification/ etiology
Female
Humans
Logistic Models
Male
Middle Aged
Monitoring, Intraoperative/ methods/statistics & numerical data
Postoperative Complications/classification/physiopathology
Prospective Studies
Sevoflurane/adverse effects/therapeutic use
Sufentanil/adverse effects/therapeutic use

Development of the AL-O-A Score for Delirium Screening in Acute Internal Medicine: a Monocentric Prospective Study John, G. Bovet, V. Verdon, V. Zender, H. Donzé, J. J Gen Intern Med 2021

adult
delirium
inpatients
internal medicine
prospective study
score

Intravenous Iron in a Prehabilitation Program for Older Surgical Patients: Prospective Cohort Study Janssen, T. L. Steyerberg, E. W. van Gammeren, A. J. Ho, G. H. Gobardhan, P. D. van der Laan, L. J Surg Res 2021

Abdomen/surgery
Aged
Aged, 80 and over
Anemia/epidemiology
Anemia, Iron-Deficiency/drug therapy/epidemiology
Blood Transfusion/statistics & numerical data
Cohort Studies
Delirium/epidemiology
Elective Surgical Procedures
Female
Hemoglobins/analysis
Humans
Infusions, Intravenous
Iron/ administration & dosage
Male
Postoperative Complications/epidemiology/prevention & control
Preoperative Care/ methods
Prospective Studies
(Iron deficiency) anemia
Colorectal surgery
Delirium
Vascular surgery

Comparative associations between anticholinergic burden and emergency department visits for anticholinergic adverse events in older Korean adults: a nested case-control study using national claims data for validation of a novel country-specific scale Hwang, S. Chung, J. E. Jun, K. Ah, Y. M. Kim, K. I. Lee, J. Y. BMC Pharmacol Toxicol 2021

Anticholinergic syndromes
Cholinergic antagonists
Emergency medical services
Geriatrics

Evaluation of QTc Interval Effects of Antipsychotic Medications for Intensive Care Unit Delirium in Pediatric Patients Hutchins, L. M. Shipman, A. Zimmerman, K. O. Heath, T. S. J Pediatr Pharmacol Ther 2021

QTc interval prolongation
antipsychotics
intensive care unit delirium
pediatric delirium

Implementing a Rapid, Two-Step Delirium Screening Protocol in Acute Care: Barriers and Facilitators Husser, E. K. Fick, D. M. Boltz, M. Shrestha, P. Siuta, J. Malloy, S. Overstreet, A. Leslie, D. L. Ngo, L. Jung, Y. Inouye, S. K. Marcantonio, E. R. J Am Geriatr Soc 2021

delirium
hospitalized older adults
observations

Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J. J Clin Anesth 2021

Elderly patients
General anaesthesia
Mean arterial pressure
Postoperative delirium

Personalized Blood Pressure Management During Cardiac Surgery With Cerebral Autoregulation Monitoring: A Randomized Trial Hogue, C. W. Brown, C. H. th Hori, D. Ono, M. Nomura, Y. Balmert, L. C. Srdanovic, N. Grafman, J. Brady, K. Semin Thorac Cardiovasc Surg 2021

Blood pressure
Cardiopulmonary bypass
Cerebral autoregulation
Neurological complications

Clinical Features and Outcomes of Patients with Dementia Compared to an Aging Cohort Hospitalized During the Initial New York City COVID-19 Wave Harb, A. A. Chen, R. Chase, H. S. Natarajan, K. Noble, J. M. J Alzheimers Dis 2021

Aged
Aged, 80 and over
COVID-19/ epidemiology/mortality
Comorbidity
Delirium/ epidemiology/mortality
Dementia/ epidemiology/mortality
Female
Hospital Mortality
Hospitalization
Humans
Male
New York City/epidemiology
Pandemics
Retrospective Studies
Advance directives
Covid-19
delirium
dementia
geriatrics
neurology

Perioperative Multidisciplinary Delirium Prevention: A Longitudinal Case Report Hamlet, K. M. Pasternak, E. Rabai, F. Mufti, M. Hernaiz Alonso, C. Price, C. C. A A Pract 2021
Cerebrospinal Fluid Concentration of Neurogranin in Hip Fracture Patients with Delirium Halaas, N. B. Zetterberg, H. Idland, A. V. Knapskog, A. B. Watne, L. O. Blennow, K. J Alzheimers Dis 2021

Alzheimer’s disease
biomarkers
cerebrospinal fluid proteins
delirium
neurotransmitter agents

A retrospective study of factors associated with persistent delirium Goto, H. Yamauchi, T. Okumura, K. Matsuoka, K. Toritsuka, M. Yasuno, F. Uemura, H. Kuki, K. Makinodan, M. Kishimoto, T. Psychogeriatrics 2021

Case-Control Studies
Delirium/diagnosis/epidemiology
Hospitals, General
Humans
Male
Pain
Retrospective Studies
Risk Factors
analgesic
case-control study
delirium
general hospital
persistent delirium

Association Between Early Tracheostomy and Delirium in Older Adults in the United States Gazda, A. J. Kwak, M. J. Jani, P. Dinh, K. Hussain, R. Dronavalli, G. Warner, M. Salas De Armas, I. Kumar, S. Nathan, S. Kar, B. Gregoric, I. D. Patel, B. Akkanti, B. J Cardiothorac Vasc Anesth 2021

delirium
intensive care unit
mechanical ventilation
prevention of ICU delirium
tracheostomy

Poor outcomes of delirium in the intensive care units are amplified by increasing age: A retrospective cohort study Gao, W. Zhang, Y. P. Jin, J. F. World J Emerg Med 2021

Aging
Delirium
Intensive care
Mortality

Postoperative Delirium is Associated With Prolonged Head and Neck Resection and Reconstruction Surgery: An Institutional Study Edwards, D. A. Medhavy, A. Hoffman, O. G. Hoffman, G. R. J Oral Maxillofac Surg 2021

Aged
Delirium/epidemiology/etiology
Female
Humans
Male
Postoperative Complications/epidemiology/etiology
Reconstructive Surgical Procedures
Retrospective Studies
Risk Factors

Delirium Assessment in Critically Ill Older Adults: Considerations During the COVID-19 Pandemic Duggan, M. C. Van, J. Ely, E. W. Crit Care Clin 2021

Aged
Aged, 80 and over
Betacoronavirus
Covid-19
Coronavirus Infections/ complications
Delirium/ complications/ diagnosis/prevention & control
Dementia/ complications
Hearing Loss/complications
Humans
Intensive Care Units
Pandemics
Patient Care Team
Pneumonia, Viral/ complications
SARS-CoV-2
Vision Disorders/complications
Assessment
Critical care
Delirium
Geriatrics
Intensive care unit
Older adults
Pandemic
Screening

Delirium occurrence in older Irish adults admitted to an acute medical hospital: a prospective cohort study Dolan, C. Mohd Zubir, M. Melvin, V. McCarthy, G. Meagher, D. Adamis, D. Ir J Psychol Med 2021

Delirium
epidemiology
incidence
inpatient
older adults
prevalence

Clinical utility of brain computed tomography in prediction of post-stroke delirium Czyzycki, M. Glen, A. Slowik, A. Chrzan, R. Dziedzic, T. J Neural Transm (Vienna) 2021

Brain atrophy
Delirium
Prediction
Stroke
White matter changes

Risk factors for long-term cognitive impairment in ICU survivors: A multicenter, prospective cohort study Collet, M. O. Egerod, I. Thomsen, T. Wetterslev, J. Lange, T. Ebdrup, B. H. Perner, A. Acta Anaesthesiol Scand 2021
Integration of family caregivers in delirium prevention care for hospitalized older adults: A case study analysis Cohen, C. Pereira, F. Kampel, T. Bélanger, L. J Adv Nurs 2021

Aged
Caregivers
Communication
Delirium/prevention & control
Family
Geriatric Nursing
Hospitalization
Humans
delirium
family caregivers
integration
nurses
older adults
orthopaedic surgery
prevention

Investigating how electroencephalogram measures associate with delirium: A systematic review Boord, M. S. Moezzi, B. Davis, D. Ross, T. J. Coussens, S. Psaltis, P. J. Bourke, A. Keage, H. A. D. Clin Neurophysiol 2021

Delirium
Eeg
Electroencephalography
Review

Pharmacologic Management of Intensive Care Unit Delirium: Clinical Prescribing Practices and Outcomes in More Than 8500 Patient Encounters Boncyk, C. S. Farrin, E. Stollings, J. L. Rumbaugh, K. Wilson, J. E. Marshall, M. Feng, X. Shotwell, M. S. Pandharipande, P. P. Hughes, C. G. Anesth Analg 2021
Predictors of delirium in older patients at the emergency department: a prospective multicentre derivation study Béland, E. Nadeau, A. Carmichael, P. H. Boucher, V. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Vu, T. T. M. Émond, M. CJEM 2021

Delirium
Emergency department
Predictor factors

Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort Atkins, J. L. Pilling, L. C. Heales, C. J. Savage, S. Kuo, C. L. Kuchel, G. A. Steffens, D. C. Melzer, D. J Alzheimers Dis 2021

Cohort
delirium
dementia
gene
hemochromatosis
iron
mutation

Awareness of Delirium by ICU Nurses Asmar, I. T. Yaseen, K. S. Jaghama, M. K. Khawaja, Y. F. Alwredat, A. A. Sadaqa, M. H. Crit Care Nurs Q 2021
Psychiatric Clinical Profiles and Pharmacological Interactions in COVID-19 Inpatients Referred to a Consultation Liaison Psychiatry Unit: a Cross-Sectional Study Arbelo, N. López-Pelayo, H. Sagué, M. Madero, S. Pinzón-Espinosa, J. Gomes-da-Costa, S. Ilzarbe, L. Anmella, G. Llach, C. D. Imaz, M. L. Cámara, M. M. Pintor, L. Psychiatr Q 2021

Covid-19
Consultation-liaison psychiatry
Delirium
Mental health residential facilities
Pharmacological interactions
Psychopharmacology

Octogenarian patients' sleep and delirium experiences in hospital and four years after aortic valve replacement: a qualitative interview study Amofah, H. A. Broström, A. Instenes, I. Fridlund, B. Haaverstad, R. Kuiper, K. Ranhoff, A. H. Norekvål, T. M. BMJ Open 2021

Aged, 80 and over
Aortic Valve/surgery
Aortic Valve Stenosis/surgery
Delirium/epidemiology/etiology
Female
Heart Valve Prosthesis Implantation/adverse effects
Hospitals
Humans
Male
Prospective Studies
Risk Factors
Sleep
Treatment Outcome
cardiac surgery
coronary intervention
delirium & cognitive disorders
qualitative research
sleep medicine
valvular heart disease

Delirium and quality of life in critically ill patients: a prospective cohort study Luz, L. F. D. S. Santos, M. C. D. Ramos, T. A. Almeida, C. B. Rover, M. C. Dal'Pizzol, C. P. Pohren, C. L. D. S. Martins, A. V. D. S. Boniatti, M. M. Rev Bras Ter Intensiva 2020

adult
article
Barthel index
cognitive defect
cohort analysis
controlled study
critically ill patient
female
functional status
hospital discharge
human
intensive care unit
major clinical study
male
Mini Mental State Examination
physical disability
prospective study
quality of life
questionnaire
telephone
World Health Organization

Bispectral Index Monitoring With Density Spectral Array for Delirium Detection Luo, A. Muraida, S. Pinchotti, D. Richardson, E. Ye, E. Hollingsworth, B. Win, A. Myers, O. Langsjoen, J. Valles, E. Zolyomi, A. Quinn, D. K. Psychosomatics 2020

bispectral index monitoring
delirium
density spectral array

Delirium prediction in the intensive care unit: a temporal approach Lucini, F. R. Fiest, K. M. Stelfox, H. T. Lee, J. Annu Int Conf IEEE Eng Med Biol Soc 2020

Alberta
Delirium/diagnosis
Humans
Intensive Care Units
Logistic Models
Retrospective Studies

Impact of place of residence, frailty and other factors on rehabilitation outcomes post hip fracture Low, S. Wee, E. Dorevitch, M. Age Ageing 2020

clinical frailty scale
frailty
hip fracture
older people
rehabilitation
residential care

Ramelteon for Decreasing Delirium in Surgical Intensive Care Unit Patients Lopez, C. N. Fuentes, A. Dhala, A. Balk, J. Clinical Medicine Insights: Psychiatry 2020

haloperidol
lorazepam
melatonin
neuroleptic agent
quetiapine
ramelteon
risperidone
acute disease
adult
article
artificial ventilation
cardiovascular surgery
clinical assessment
clinical evaluation
cognitive defect
cohort analysis
comparative study
confusion
delirium
disease severity
female
hemodynamics
hospital admission
hospitalization
human
incidence
intensive care unit
length of stay
liver transplantation
major clinical study
male
middle aged
Model For End Stage Liver Disease Score
mortality rate
priority journal
retrospective study
risk factor
Sequential Organ Failure Assessment Score
surgical intensive care unit

Different depths of sedation versus risk of delirium in adult mechanically ventilated patients: A systematic review and meta-analysis Long, L. Ren, S. Gong, Y. Zhao, H. He, C. Shen, L. Zhao, H. Ma, P. PLoS One 2020

Adult
Conscious Sedation/ adverse effects
Delirium/ etiology/pathology
Humans
Hypnotics and Sedatives/ adverse effects
Length of Stay
Respiration, Artificial/ adverse effects
Ventilators, Mechanical/ adverse effects

Association of Troponin Levels With Mortality in Italian Patients Hospitalized With Coronavirus Disease 2019: Results of a Multicenter Study Lombardi, C. M. Carubelli, V. Iorio, A. Inciardi, R. M. Bellasi, A. Canale, C. Camporotondo, R. Catagnano, F. Dalla Vecchia, L. A. Giovinazzo, S. Maccagni, G. Mapelli, M. Margonato, D. Monzo, L. Nuzzi, V. Oriecuia, C. Peveri, G. Pozzi, A. Provenzale, G. S JAMA Cardiol 2020

Aged
Aged, 80 and over
COVID-19/ blood/epidemiology/ mortality/virology
Cardiovascular Diseases/ blood/epidemiology
Comorbidity
Cross-Sectional Studies
Female
Hospital Mortality/trends
Hospitalization/statistics & numerical data
Humans
Italy/epidemiology
Male
Middle Aged
Prevalence
Risk Factors
SARS-CoV-2/ genetics
Troponin I/blood
Troponin T/blood

Role of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis Liu, X. Xiong, J. Tang, Y. Gong, C. C. Wang, D. F. Minerva anestesiologica 2020

adult
article
bradycardia
clinical trial
Cochrane Library
comparative effectiveness
critically ill patient
delirium
drug efficacy
drug safety
drug therapy
Embase
female
human
incidence
male
Medline
pharmacokinetics
prevalence
randomized controlled trial (topic)
systematic review
Web of Science
dexmedetomidine
haloperidol
placebo

Delirium Severity Trajectories and Outcomes in ICU Patients. Defining a Dynamic Symptom Phenotype Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. Ann Am Thorac Soc 2020

critical care
delirium
delirium severity
prediction
trajectory of illness

Risk factors for postoperative delirium in patients with triple-branched stent graft implantation Lin, Y. Chen, Q. Zhang, H. Chen, L. W. Peng, Y. Huang, X. Chen, Y. Li, S. Lin, L. J Cardiothorac Surg 2020

Apache
Aneurysm, Dissecting/ surgery
Aortic Aneurysm, Thoracic/ surgery
Delirium/ etiology
Female
Humans
Incidence
Japan
Male
Middle Aged
Postoperative Complications/ etiology
Proportional Hazards Models
Retrospective Studies
Risk Factors
Stents
Aortic dissection
Postoperative delirium
Triple-branched stent graft implantation

Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study Lin, X. Tang, J. Liu, C. Li, X. Cao, X. Wang, B. Dong, R. Xu, W. Yu, X. Wang, M. Bi, Y. BMC Anesthesiol 2020

Cerebrospinal fluid
Cholinergic
Elderly
Postoperative delirium

Effect of Dexmedetomidine on Delirium in Elderly Surgical Patients: A Meta-analysis of Randomized Controlled Trials Lin, C. Tu, H. Jie, Z. Zhou, X. Li, C. Ann Pharmacother 2020

delirium
dexmedetomidine
elderly surgical patients
meta-analysis

The relationship between intraoperative cerebral oximetry and postoperative delirium in patients undergoing off-pump coronary artery bypass graft surgery: a retrospective study Lim, L. Nam, K. Lee, S. Cho, Y. J. Yeom, C. W. Jung, S. Moon, J. Y. Jeon, Y. BMC Anesthesiol 2020

Cerebral oximetry
Delirium
Off-pump coronary artery bypass graft surgery

Effects of nonpharmacological delirium-prevention interventions on critically ill patients' clinical, psychological, and family outcomes: A systematic review and meta-analysis Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Choi, K. C. Aust Crit Care 2020

Delirium
Intensive care units
Meta-analysis
Systematic review

Validation of PREdiction of DELIRium in ICu patients (PRE-DELIRIC) among patients in intensive care units: A retrospective cohort study Liang, S. Chau, J. P. C. Lo, S. H. S. Bai, L. Yao, L. Choi, K. C. Nurs Crit Care 2020

Icu
Predeliric
delirium
prevention
risk factor

Prognostic Impact of Delirium in Older People With/Without Dementia: A Retrospective Cohort Study in Taiwan Liang, C. K. Chuang, H. Y. Hsiao, F. Y. Chou, M. Y. Liu, T. Y. Yang, C. C. Chen, L. K. Journal of Nutrition, Health and Aging 2020

aged
article
awareness
cohort analysis
controlled study
delirium
dementia
emergency ward
female
follow up
health care utilization
hospital readmission
human
major clinical study
male
mortality
national health insurance
prognosis
propensity score
public hospital
retrospective study
Taiwan
psychotropic agent

Effects of modified version of the Hospital Elder Life Program on post-discharge cognitive function and activities of daily living among older adults undergoing total knee arthroplasty Liang, C. K. Chu, C. S. Hsu, Y. H. Chou, M. Y. Wang, Y. C. Lin, Y. T. Renn, J. H. Liu, T. Y. Yang, C. C. Arch Gerontol Geriatr 2020

Cognitive decline
Delirium
Functional decline
Intervention
Total knee arthroplasty

Incidence and Risk Factors for Delirium in Older Patients Following Intensive Care Unit Admission: A Prospective Observational Study Li, X. Zhang, L. Gong, F. Ai, Y. The journal of nursing research : JNR 2020

aged
article
China
controlled study
critically ill patient
delirium
demography
doctor nurse relation
female
human
incidence
intensive care unit
major clinical study
male
observational study
prospective study
Richmond Agitation Sedation Scale
risk factor
sleep quality
fentanyl

Surviving and Thriving 1 Year After Cardiac Surgery: Frailty and Delirium Matter Li, H. C. Wei, Y. C. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. H. Inouye, S. K. Annals of Thoracic Surgery 2020

ADL disability
adult
all cause mortality
article
Barthel index
controlled study
female
frailty
heart surgery
human
major clinical study
male
phenotype
postoperative delirium
preoperative evaluation
prevention
surgery
university hospital

Pharmacist Identification of Medication Therapy Problems Involving Cognition Among Older Adults Followed by a Home-Based Care Team Levine, A. M. P. Emonds, E. E. Smith, M. A. Rickles, N. M. Kuchel, G. A. Steffens, D. C. Ohlheiser, A. Fortinsky, R. H. Drugs and Aging 2020

aged
article
clinical pharmacist
cognition
Connecticut
controlled study
dementia
drug megadose
drug overdose
drug safety
drug therapy
drug withdrawal
female
geriatrician
human
International Classification of Diseases
low drug dose
major clinical study
male
medicare
medication therapy management
multidisciplinary team
pharmacokinetics
potentially inappropriate medication
primary medical care
psychiatrist
randomized controlled trial
registered nurse
retrospective study
side effect
antidepressant agent
benzodiazepine derivative
cholinergic receptor blocking agent

Multicomponent Interventions for the Prevention of Delirium in Hospitalized Older People: A Meta-Analysis León-Salas, B. Trujillo-Martín, M. M. Martínez Del Castillo, L. P. García-García, J. Pérez-Ros, P. Rivas-Ruiz, F. Serrano-Aguilar, P. J Am Geriatr Soc 2020

delirium
hospitalization
meta-analysis
multicomponent
older people
prevention

Pharmacologic interventions for prevention of delirium in hospitalized older people: A meta-analysis León-Salas, B. Trujillo-Martín, M. M. Del Castillo, L. P. M. García, J. G. Pérez-Ros, P. Ruiz, F. R. Serrano-Aguilar, P. Arch Gerontol Geriatr 2020

Aged
Aged, 80 and over
Antipsychotic Agents/therapeutic use
Delirium/drug therapy/prevention & control
Humans
Incidence
Postoperative Complications
Time Factors
Delirium
Hospitalization
Meta-Analysis
Older
Pharmacologic intervention
Prevention

"You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. J Clin Nurs 2020

Aged
Aged, 80 and over
Critical Care Nursing/ methods
Delirium/nursing/ prevention & control/psychology
Female
Hospitalization
Humans
Male
Nurse-Patient Relations
Patient-Centered Care/ methods
Qualitative Research
adult
awareness
caregivers
delirium
exercise
inpatients
perception

The Effect of Intraoperative Magnesium Sulphate Infusion on Emergence Agitation after Ambulatory Ophthalmic Surgery in Children Lee, Y. J. Kim, B. Y. Park, J. H. Kim, S. Y. Park, H. Y. Do, S. H. J Clin Med 2020

ambulatory surgery
emergence agitation
magnesium sulphate
ophthalmic surgery
paediatric patients

Effects of the ABCDE bundle on the prevention of post-intensive care syndrome: A retrospective study Lee, Y. Kim, K. Lim, C. Kim, J. S. Journal of advanced nursing 2020

adult
aged
chronic disease
coma
comparative study
critical illness
delirium
female
human
intensive care
length of stay
male
middle aged
nursing
physiology
procedures
retrospective study
survivor
very elderly
walking

Effect of Antipsychotics and Non-Pharmacotherapy for the Management of Delirium in People Receiving Palliative Care Lee, K. Y. Tan, E. C. K. Hanrahan, J. R. Chircop, C. Michael, F. Ong, J. A. J Pain Palliat Care Pharmacother 2020

Delirium
anti-psychotics
palliative care

Effect of magnesium supplementation on emergence delirium and postoperative pain in children undergoing strabismus surgery: a prospective randomised controlled study Lee, J. H. Choi, S. Lee, M. Jang, Y. E. Kim, E. H. Kim, J. T. Kim, H. S. BMC Anesthesiol 2020

Emergence delirium
Magnesium
Ophthalmologic surgical procedure
Paediatrics
Pain

Neurologic Complications in Patients With Cancer Lee, E. Q. Continuum (Minneapolis, Minn.) 2020

adult
article
aspergillosis
blood clotting
brain hemorrhage
cancer patient
central nervous system infection
cerebrovascular accident
chimeric antigen receptor T-cell immunotherapy
complication
delirium
diagnosis
differential diagnosis
early diagnosis
effector cell
human
neurological complication
angiogenesis inhibitor
ibrutinib

Melatonin to prevent delirium in patients with advanced cancer: a double blind, parallel, randomized, controlled, feasibility trial Lawlor, P. G. McNamara-Kilian, M. T. MacDonald, A. R. Momoli, F. Tierney, S. Lacaze-Masmonteil, N. Dasgupta, M. Agar, M. Pereira, J. L. Currow, D. C. Bush, S. H. BMC Palliat Care 2020

Advanced cancer
Delirium
Feasibility study
Melatonin
Pilot
Prevention
Randomized controlled trial
Sleep

Cognitive function and health-related quality of life 1 year after acute brain injury: An observational study Larsen, L. K. Møller, K. Petersen, M. Egerod, I. Acta Anaesthesiol Scand 2020

Acute brain injury
cognitive impairment
delirium
health-related quality of life
neuro intensive care unit

The One-Two Punch of Delirium and Dementia During the COVID-19 Pandemic and Beyond LaHue, S. C. Douglas, V. C. Miller, B. L. Front Neurol 2020

Alzheimer’s disease and related dementias (ADRD)
Covid-19
accessibility
delirium
dementia
hospitalization
technology

Postoperative Delirium is a Risk Factor of Poor Evolution Three Years After Cardiac Surgery: An Observational Cohort Study Labaste, F. Porterie, J. Bousquet, P. Marcheix, B. Sanchez-Verlaan, P. Frances, B. Valet, P. Dray, C. Minville, V. Clin Interv Aging 2020

cardiac surgery
delirium
dependence
mortality
quality of life

Delirium among Hospitalized Older Adults with Acute Heart Failure Exacerbation Kwak, M. J. Avritscher, E. Holmes, H. M. Jantea, R. Flores, R. Rianon, N. Chung, T. H. Balan, P. Dhoble, A. J Card Fail 2020

Acute Heart Failure
Delirium
Hospital Cost
Length of Stay
Older Adults

Association between polypharmacy and the persistence of delirium: a retrospective cohort study Kurisu, K. Miyabe, D. Furukawa, Y. Shibayama, O. Yoshiuchi, K. Biopsychosoc Med 2020

Classification and regression tree
Delirium
Polypharmacy
Propensity score
Receiver operating characteristic curve

Elevated Procalcitonin as a Risk Factor for Postoperative Delirium in the Elderly after Cardiac Surgery-A Prospective Observational Study Kupiec, A. Adamik, B. Kozera, N. Gozdzik, W. J Clin Med 2020

cardiac surgery
delirium
depression
elderly
functional decline
procalcitonin

The CAM-ICU-7 and ICDSC as measures of delirium severity in critically ill adult patients Krewulak, K. D. Rosgen, B. K. Ely, E. W. Stelfox, H. T. Fiest, K. M. PLoS One 2020

Adult
Aged
Critical Care/methods
Critical Illness/ classification
Cross-Sectional Studies
Delirium/ classification/diagnosis
Female
Humans
Intensive Care Units
Length of Stay/statistics & numerical data
Logistic Models
Male
Mass Screening/ methods
Middle Aged
Odds Ratio
Prevalence

Adaptation and Validation of a Chart-Based Delirium Detection Tool for the ICU (CHART-DEL-ICU) Krewulak, K. D. Hiploylee, C. Ely, E. W. Stelfox, H. T. Inouye, S. K. Fiest, K. M. J Am Geriatr Soc 2020

Confusion Assessment Method for Intensive Care Unit (CAM-ICU)
Intensive Care Delirium Screening Checklist (ICDSC)
critical care
delirium screening
intensive care unit

Effectiveness of an intensive care unit family education intervention on delirium knowledge: a pre-test post-test quasi-experimental study Krewulak, K. D. Bull, M. J. Wesley Ely, E. Davidson, J. E. Stelfox, H. T. Fiest, K. M. Can J Anaesth 2020

Critical care
Delirium education
Family
Intensive care unit

Assessment and Management of Delirium in Critically Ill Veterans Kresevic, D. M. Miller, D. Fuseck, C. W. Wade, M. Whitney, L. Conley, M. Rimac, J. Jacono, F. O'Leary-Wilson, H. L. Burant, C. J. Critical care nurse 2020

article
breathing
controlled study
critically ill patient
delirium
doctor nurse relation
education program
hip
human
leadership
medical record
pain assessment
screening test
sedation
simulation training
surgical intensive care unit
total quality management
veteran

Delirium Post-Stroke: Short- and Long-Term Effect on Depression, Anxiety, Apathy and Aggression (Research Study-Part of PROPOLIS Study) Kowalska, K. Droś, J. Mazurek, M. Pasińska, P. Gorzkowska, A. Klimkowicz-Mrowiec, A. J Clin Med 2020

aggression
anxiety
apathy
depression
post-stroke delirium
stroke

Intrathecal Morphine Is Associated with Less Delirium Following Hip Fracture Surgery: A Register Study Koning, M. V. van der Sijp, M. Stolker, R. J. Niggebrugge, A. Anesth Pain Med 2020

Delirium
Femoral Fractures
Morphine
Spinal Anesthesia
Spinal Injections

Evaluation of Pediatric Delirium Awareness and Management in Pediatric Intensive Care Units in Turkey Konca, C. Anil, A. B. Küllüoglu, E. P. Luleyap, D. Anil, M. Tekin, M. Journal of Pediatric Intensive Care 2020

Awareness

Delirium

Management

Pediatric

Turkey

Preventive effect of ramelteon on emergence agitation after general anaesthesia in paediatric patients undergoing tonsillectomy: a randomised, placebo-controlled clinical trial Komazaki, M. Mihara, T. Nakamura, N. Ka, K. Goto, T. Sci Rep 2020
Delirium in burn patients: developing a mobile application for assessment and diagnosis Kolaei, N. M. M. Ayatollahi, H. Elyasi, F. J Burn Care Res 2020

Burn
Delirium
Delirium screening
Mobile application

Delirium at the end of life Knoepfel, S. Bode, L. Gehrke, S. Spiller, T. Fuchs, S. Ernst, J. von Känel, R. Boettger, S. Palliat Support Care 2020

Delirium at the end of life
In-hospital mortality
Interrelationship of delirium and death
Terminal delirium

Protocol for the effectiveness of an anesthesiology control tower system in improving perioperative quality metrics and clinical outcomes: The tectonics randomized, pragmatic trial King, C. R. Abraham, J. Kannampallil, T. G. Fritz, B. A. Abdallah, A. B. Chen, Y. Henrichs, B. Politi, M. Torres, B. A. Mickle, A. Budelier, T. P. McKinnon, S. Gregory, S. Kheterpal, S. Wildes, T. Avidan, M. S. Tectonics Research, Group F1000Research 2020

NCT02032030
NCT03923699
AlertWatch
anesthesiology control tower system
anesthesiology monitoring device
operating room
antibiotic agent
glucose
acute kidney failure
adult
airway pressure
anesthesia level
article
artificial ventilation
clinical effectiveness
clinical outcome
clinical protocol
controlled study
gas flow
glucose blood level
human
intention to treat analysis
major clinical study
mean airway pressure
mean arterial pressure
perioperative period
phase 3 clinical trial
postoperative delirium
randomized controlled trial
respiratory failure
surgical mortality
surgical technique
temperature measurement

Sleep disturbance and delirium in patients with acromegaly in the early postoperative period after transsphenoidal pituitary surgery Kim, S. H. Kim, N. Min, K. T. Kim, E. H. Oh, H. Choi, S. H. Medicine (Baltimore) 2020

Acromegaly/ surgery
Adult
Aged
Delirium/ epidemiology
Endocrine Surgical Procedures/methods
Female
Humans
Incidence
Male
Middle Aged
Pituitary Neoplasms/ surgery
Postoperative Complications/ epidemiology
Retrospective Studies
Sleep Wake Disorders/ epidemiology
Sphenoid Sinus
Time Factors

Frontal electroencephalogram activity during emergence from general anaesthesia in children with and without emergence delirium Kim, J. Lee, H. C. Byun, S. H. Lim, H. Lee, M. Choung, Y. Kim, E. Br J Anaesth 2020

brain waves
children
electroencephalogram (EEG)
emergence delirium
neurocognitive disorders
post operative delirium
sevoflurane anaesthesia

Safety and efficacy of pharmacologic agents used for rapid tranquilization of emergency department patients with acute agitation or excited delirium Kim, H. K. Leonard, J. B. Corwell, B. N. Connors, N. J. 2020

acute agitation
emergency department
excited delirium
excited delirium syndrome
rapid tranquilization
safety

Effect of Timing of Intravenous Fentanyl Administration on the Incidence of Posttonsillectomy Nausea and Vomiting Kim, H. J. Kim, M. S. Kim, H. Y. Park, W. K. Kim, W. S. Kim, S. Kim, H. J. Laryngoscope 2020

Postoperative nausea and vomiting
emergence delirium
fentanyl
pain, postoperative
tonsillectomy

Effect on Quality of Care of a Delirium Prevention Campaign for Surgical Intensive Care Nurses Kim, H. Lee, S. M. Publish Ahead of Print 2020
Ultrasound-Guided Pecto-Intercostal Fascial Block for Postoperative Pain Management in Cardiac Surgery: A Prospective, Randomized, Placebo-Controlled Trial Khera, T. Murugappan, K. R. Leibowitz, A. Bareli, N. Shankar, P. Gilleland, S. Wilson, K. Oren-Grinberg, A. Novack, V. Venkatachalam, S. Rangasamy, V. Subramaniam, B. J Cardiothorac Vasc Anesth 2020

3-minute diagnostic Confusion Assessment Method
3d-cam
Pifb
Pecto-intercostal fascial plane block
Vas
cardiac surgery
pain scores
postoperative delirium
visual analog scale

Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019 Khan, S. H. Lindroth, H. Perkins, A. J. Jamil, Y. Wang, S. Roberts, S. Farber, M. Rahman, O. Gao, S. Marcantonio, E. R. Boustani, M. Machado, R. Khan, B. A. Crit Care Explor 2020

brain diseases
coma
coronavirus disease 2019
critical illness
delirium
respiratory insufficiency

Delirium, Cerebral Perfusion and High Frequency Vital Sign Monitoring in the Critically Ill: The CONFOCAL-2 Feasibility Study Khan, J. M. Wood, M. D. Lee, K. F. H. Maslove, D. Muscedere, J. English, S. W. Ball, I. Slessarev, M. Boyd, J. G. Annals of the American Thoracic Society 2020

NCT03141619
adult
area under the curve
arterial line
article
artificial ventilation
autoregulation
blood gas
brain perfusion
cognitive defect
controlled study
critically ill patient
feasibility study
female
follow up
forehead
heart rate
human
intensive care unit
major clinical study
male
mean arterial pressure
multicenter study
near infrared spectroscopy
observational study
prospective study
respiratory failure
sensor
tissue oxygenation
vital sign