Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Postoperative Delirium and the Older Adult: Untangling the Confusion
Authors
Thedim, M. Vacas, S.
Year
2024
Journal
J Neurosurg Anesthesiol
Abstract

Postoperative delirium is one of the most prevalent postoperative complications, affecting mostly older adults. Its incidence is expected to rise because of surgical advances, shifting demographics, and increased life expectancy. Although an acute alteration in brain function, postoperative delirium is associated with adverse outcomes, including progressive cognitive decline and dementia, that place significant burdens on patients’ lives and healthcare systems. This has prompted efforts to understand the mechanisms of postoperative delirium to provide effective prevention and treatment. There are multiple mechanisms involved in the etiology of postoperative delirium that share similarities with the physiological changes associated with the aging brain. In addition, older patients often have multiple comorbidities including increased cognitive impairment that is also implicated in the genesis of delirium. These tangled connections pinpointed a shift toward creation of a holistic model of the pathophysiology of postoperative delirium. Scientific advancements integrating clinical risk factors, possible postoperative delirium biomarkers, genetic features, digital platforms, and other biotechnical and information technological innovations, will become available in the near future. Advances in artificial intelligence, for example, will aggregate cognitive testing platforms with patient-specific postoperative delirium risk stratification studies, panels of serum and cerebrospinal fluid molecules, electroencephalogram signatures, and gut microbiome features, along with the integration of novel polygenetic variants of sleep and cognition. These advances will allow for the enrollment of high-risk patients into prevention programs and help uncover new pharmacologic targets.

PMID

PMID: 38683185

Keywords

aging, anesthesia, delirium, inflammation, sleep

Page(s)
Issue

Search:
Total Records Found: 6050, showing 100 per page
TitleAuthorsJournalYearKeywords
Socioeconomic Factors and Intensive Care Unit-Related Cognitive Impairment Haddad, D. N. Mart, M. F. Wang, L. Lindsell, C. J. Raman, R. Nordness, M. F. Sharp, K. W. Pandharipande, P. P. Girard, T. D. Ely, E. W. Patel, M. B. Ann Surg 2020

Aged
Cognitive Dysfunction/ epidemiology/etiology
Female
Humans
Intensive Care Units
Male
Middle Aged
Prospective Studies
Risk Factors
Socioeconomic Factors
Time Factors

Opioid use is Associated with ICU Delirium in Mechanically Ventilated Children Gupta, N. Woolley, A. Talathi, S. Davlyatov, G. Colston, C. Hayes, L. J Crit Care Med (Targu Mures) 2020

intensive care unit
mechanically ventilated children
pediatric delirium

A two-year multicenter point prevalence study of older patients with hip fractures admitted to rehabilitation units in Italy Guerzoni, V. Lanzoni, A. Pozzi, C. Paci, M. Gatti, R. Benedetti, M. G. Gentile, S. Trabucchi, M. Bellelli, G. Morandi, A. Eur Geriatr Med 2020

Delirium
Dementia
Elderly
Fragility fractures
Geriatric syndromes
Hip fractures

Preoperative Cognitive Impairment and Postoperative Delirium Predict Decline in Activities of Daily Living after Cardiac Surgery-A Prospective, Observational Cohort Study Guenther, U. Hoffmann, F. Dewald, O. Malek, R. Brimmers, K. Theuerkauf, N. Putensen, C. Popp, J. Geriatrics (Basel) 2020

activity of daily living
cardiac
cognition
cognitive
delirium
intensive care
older people
outcomes
surgery

Risk Factors for Delirium and Cognitive Decline Following Coronary Artery Bypass Grafting Surgery: A Systematic Review and Meta-Analysis Greaves, D. Psaltis, P. J. Davis, D. H. J. Ross, T. J. Ghezzi, E. S. Lampit, A. Smith, A. E. Keage, H. A. D. J Am Heart Assoc 2020

cognitive decline
coronary artery bypass grafting
delirium
meta‐analysis

Prevalence and risk factors of delirium in the intensive care unit: An observational study Gravante, F. Giannarelli, D. Pucci, A. Gagliardi, A. M. Mitello, L. Montagna, A. Latina, R. Nurs Crit Care 2020

delirium
epidemiology
intensive care units
prevalence
risk factors
trauma units

Health Care Professionals' Reports of Cancer Pain Cues Among Older People With Delirium: A Qualitative-Quantitative Content Analysis Graham, C. A. Chaves, G. Harrison, R. Gauthier, L. R. Nissim, R. Zimmermann, C. Chan, V. Rodin, G. Stevens, B. Gagliese, L. J Pain Symptom Manage 2020

Cancer pain
delirium
older people
pain assessment

Benzodiazepinics and the treatment of delirium: a literature review Gonçalves, O. H. P. Pellissari, G. M. Paiva, H. S. Rev Assoc Med Bras (1992) 2020

Benzodiazepines/therapeutic use
Cognition
Delirium/drug therapy
Humans
Risk Factors

Analysis of Delirium from the Dynamic Symptoms Model: A Literature Review Gómez Tovar, L. O. Henao Castaño, A. M. Critical Care Nursing Quarterly 2020

conceptual framework
delirium
Dynamic Symptoms Model
experience
human
review
symptom assessment
systematic review

Association of delirium with long-term cognitive decline: A meta-analysis Goldberg, T. E. Chen, C. Wang, Y. Jung, E. Swanson, A. Ing, C. Garcia, P. S. Whittington, R. A. Moitra, V. JAMA Neurology 2020

article
cognition
cognitive defect
delirium
disease association
effect size
follow up
human
meta analysis
priority journal
prognosis
risk assessment
risk factor
statistical analysis
surgery
systematic review

Functional and cognitive decline in older delirious adults after an emergency department visit Giroux, M. Émond, M. Nadeau, A. Boucher, V. Carmichael, P. H. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Sirois, M. J. Age Ageing 2020

cognitive decline
delirium
emergency department
functional decline
older people
seniors

The prevalence rates and sequelae of delirium at age older than 90 years Gehrke, S. Bode, L. Seiler, A. Ernst, J. von Känel, R. Boettger, S. Palliat Support Care 2020

Delirium
Impact of delirium
Older than 90 years
Prevalence rate
Sequelae

Complications of LVAD utilization in older adults Gazda, A. J. Kwak, M. J. Akkanti, B. Nathan, S. Kumar, S. de Armas, I. S. Baer, P. Patel, B. Kar, B. Gregoric, I. D. Heart and Lung 2020

aged
article
clinical feature
complication
controlled study
female
heart failure
hospital mortality
hospital patient
human
implantation
incidence
left ventricular assist device
major clinical study
male
outcome assessment
postoperative delirium
retrospective study

Consolidated framework for advancing implementation science for the implementation process and adherence assessment of a non-pharmacological delirium prevention program Garrido, M. A. Alvarez, E. A. Ponce, D. P. Salech, F. Tobar, D. I. Tobar, E. A. Int J Geriatr Psychiatry 2020

Cfir
adherence
delirium
implementation
non-pharmacological intervention
prevention

Delirium and Adverse Outcomes in Hospitalized Patients with COVID-19 Garcez, F. B. Aliberti, M. J. R. Poco, P. C. E. Hiratsuka, M. Takahashi, S. D. F. Coelho, V. A. Salotto, D. B. Moreira, M. L. V. Jacob-Filho, W. Avelino-Silva, T. J. Journal of the American Geriatrics Society 2020

mechanical ventilator
albumin
C reactive protein
D dimer
adult
adverse outcome
aged
article
Brazil
controlled study
coronavirus disease 2019
delirium
disease association
female
glomerulus filtration rate
hospital discharge
hospital mortality
hospital patient
human
intensive care unit
length of stay
longitudinal study
lymphocyte count
lymphocytopenia
major clinical study
male
medical record review
middle aged
observational study
oxygen therapy
prognosis
retrospective study
telephone interview
university hospital
very elderly
vital sign

The Effects of Melatonin Supplementation on Sleep Quality and Assessment of the Serum Melatonin in ICU Patients: A Randomized Controlled Trial Gandolfi, J. V. Di Bernardo, A. P. A. Chanes, D. A. V. Martin, D. F. Joles, V. B. Amendola, C. P. Sanches, L. C. Ciorlia, G. L. Lobo, S. M. Critical care medicine 2020

adult
anxiety
article
artificial ventilation
clinical trial
controlled study
critically ill patient
delirium
double blind procedure
drug therapy
enzyme linked immunosorbent assay
female
hospitalization
human
human tissue
major clinical study
male
maximum plasma concentration
multicenter study
night sleep
nurse
pain
prevalence
questionnaire
randomized controlled trial
sleep quality
tertiary care center
analgesic agent
melatonin
placebo
sedative agent

Atypical presentation of COVID-19 in hospitalised older adults Gan, J. M. Kho, J. Akhunbay-Fudge, M. Choo, H. M. Wright, M. Batt, F. Mandal, A. K. J. Chauhan, R. Missouris, C. G. Ir J Med Sci 2020

Atypical symptoms
Covid-19
Coronavirus
Older adults

Delirium in elderly patients: Prospective prevalence across hospital services Fuchs, S. Bode, L. Ernst, J. Marquetand, J. von Känel, R. Böttger, S. Gen Hosp Psychiatry 2020

>65 years
Admission
Delirium
Discharge
Elderly
Hospital services

Ascertainment of delirium status using natural language processing from electronic health records Fu, S. Lopes, G. S. Pagali, S. R. Thorsteinsdottir, B. LeBrasseur, N. K. Wen, A. Liu, H. Rocca, W. A. Olson, J. E. St Sauver, J. Sohn, S. J Gerontol A Biol Sci Med Sci 2020

confusion assessment method
delirium
electronic health records
natural language processing

A Multi-Phase Quality Improvement Initiative for the Treatment of Active Delirium in Older Persons Friedman, J. I. Li, L. Kirpalani, S. Zhong, X. Freeman, R. Cheng, Y. T. Alfonso, F. L. McAlpine, G. Vakil, A. Macon, B. Francaviglia, P. Cassara, M. LoPachin, V. Reina, K. Davis, K. Reich, D. Craven, C. K. Mazumdar, M. Siu, A. L. J Am Geriatr Soc 2020

Confusion Assessment Method
active delirium treatment program
delirium prevention program
electronic medical record

Delirium diagnostic tool-provisional (DDT-Pro) scores in delirium, subsyndromal delirium and no delirium Franco, J. G. Trzepacz, P. T. Sepúlveda, E. Ocampo, M. V. Velásquez-Tirado, J. D. Zaraza, D. R. Restrepo, C. Giraldo, A. M. Serna, P. A. Zuluaga, A. López, C. Gen Hosp Psychiatry 2020

Cluster analysis
Delirium phenotype
Geriatric assessment
Psychiatric nosology
Psychiatric status rating scales
Subsyndromal delirium

A multimodal sevoflurane-based sedation regimen in combination with targeted temperature management in post-cardiac arrest patients reduces the incidence of delirium: An observational propensity score-matched study Foudraine, N. A. Algargoush, A. van Osch, F. H. Bos, A. T. Resuscitation 2020

Cardiac arrest
Delirium
Post-anoxic encephalopathy
Temperature management
Volatile anaesthetics

Association of Plasma Neurofilament Light with Postoperative Delirium Fong, T. G. Vasunilashorn, S. M. Ngo, L. Libermann, T. A. Dillon, S. T. Schmitt, E. M. Pascual-Leone, A. Arnold, S. E. Jones, R. N. Marcantonio, E. R. Inouye, S. K. Ann Neurol 2020

Aged
Aged, 80 and over
Cognition
Cognitive Dysfunction/etiology/psychology
Cohort Studies
Elective Surgical Procedures/adverse effects/psychology
Emergence Delirium/ blood/psychology
Female
Glial Fibrillary Acidic Protein/blood
Humans
Incidence
Male
Neurofilament Proteins/ blood
Neuropsychological Tests
Postoperative Complications/psychology
Prospective Studies
Psychomotor Performance
tau Proteins/blood

Course and Recognition of Poststroke Delirium: A Prospective Noninferiority Trial of Delirium Screening Tools Fleischmann, R. Warwas, S. Andrasch, T. Kunz, R. Witt, C. Mengel, A. von Sarnowski, B. Stroke 2020

delirium
incidence
risk factors
screening
sensitivity and specificity
stroke

The collateral history: an overlooked core clinical skill Fitzpatrick, D. Doyle, K. Finn, G. Gallagher, P. Eur Geriatr Med 2020

Clinical training
Cognitive impairment
Collateral history
Delirium
Dementia
Informant history

Management of delirium superimposed on dementia in a dementia service FitzGerald, J. Yan, M. Bandecar, A. Ratnasabapathy, V. Rubinsztein, J. Hatfield, C. Ruhi, S. Progress in Neurology and Psychiatry 2020

adult
article
automutilation
clinical audit
cohort analysis
delirium
dementia
female
health service
home care
hospital discharge
hospitalization
human
intensive care unit
Lewy body
male
mental health
mental health service
middle aged
outcome assessment
Parkinson disease
patient care
phenotype
posttraumatic stress disorder
priority journal
psychiatry
quality control
schizophrenia

Partnering With Family Members to Detect Delirium in Critically Ill Patients Fiest, K. M. Krewulak, K. D. Ely, E. W. Davidson, J. E. Ismail, Z. Sept, B. G. Stelfox, H. T. Crit Care Med 2020

adult
article
brain injury
checklist
clinical assessment
cognition
controlled study
critically ill patient
diagnostic accuracy
diagnostic test accuracy study
health care quality
human
informed consent
intensive care psychosis
intensive care unit
major clinical study
male
nurse
patient care
receiver operating characteristic
Richmond Agitation Sedation Scale
sensitivity and specificity
spouse
tertiary health care
university hospital
validation study

The correlation of intraoperative hypotension and postoperative cognitive impairment: a meta-analysis of randomized controlled trials Feng, X. Hu, J. Hua, F. Zhang, J. Zhang, L. Xu, G. BMC Anesthesiol 2020

Intraoperative hypotension
Meta-analysis
Postoperative cognitive dysfunction
Postoperative delirium

The effect of joints range of motion exercises on delirium prevention in patients admitted to intensive care units Farzammanesh, A. Jahani, S. Rashidi, M. Maraghi, E. Ravanbakhsh, M. International Journal of Pharmaceutical and Phytopharmacological Research 2020

IRCT20180114038362N1
adult
article
checklist
clinical outcome
controlled study
exercise
female
hospital admission
hospital discharge
human
intensive care psychosis
joint mobilization
major clinical study
male
randomized controlled trial
range of motion

Sleep and Delirium in Older Adults Farasat, S. Dorsch, J. J. Pearce, A. K. Moore, A. A. Martin, J. L. Malhotra, A. Kamdar, B. B. Curr Sleep Med Rep 2020

Acetylcholine
Aging
Delirium
Dopamine
Intensive care
Sleep

Association between use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and postoperative delirium Farag, E. Farag, E. Liang, C. Liang, C. Mascha, E. J. Mascha, E. J. Argalious, M. Y. Ezell, J. Maheshwari, K. Esa, W. A. S. Troianos, C. A. Sessler, D. I. Anesthesiology 2020

adult
Alzheimer disease
article
clinical trial
cohort analysis
controlled study
drug therapy
female
human
incidence
intensive care unit
major clinical study
male
neurosurgery
postoperative delirium
preoperative evaluation
randomized controlled trial
angiotensin
angiotensin receptor antagonist
dipeptidyl carboxypeptidase
dipeptidyl carboxypeptidase inhibitor
endogenous compound

Delirium in cardiology: An old problem, a new emergency Falsini, G. Romanelli, S. Insana, L. Frongillo, D. Grotti, S. Angioli, P. Ducci, K. Liistro, F. Calchetti, B. Rossi, R. Bolognese, L. Giornale Italiano di Cardiologia 2020

attitude to illness
cardiology
delirium
human
patient care
prognosis
prophylaxis
review

Surveying work-as-done in post-operative delirium risk factors collection and diagnosis monitoring Falegnami, A. Patriarca, R. Costantino, F. Di Gravio, G. Bilotta, F. Appl Ergon 2020

RiskSOAP
Stamp
Team awareness

Psychiatric disorders, delirium and mortality in patients referred for consultation in a burn center: A four-year retrospective study Erdoğan, E. Delibaş, D. H. Medical Journal of Bakirkoy 2020

antidepressant agent
benzodiazepine derivative
neuroleptic agent
psychotropic agent
acute stress disorder
adjustment disorder
adult
adult respiratory distress syndrome
aged
anxiety disorder
article
bipolar disorder
burn
burn unit
cause of death
consultation
delirium
depression
drug dependence
female
heart arrest
high risk patient
human
length of stay
major clinical study
male
mental disease
morbidity
mortality
multiple organ failure
psychiatric diagnosis
psychosis
retrospective study
sepsis

Delirium in Older People with COVID-19: Clinical Scenario and Literature Review Emmerton, D. Abdelhafiz, A. SN Compr Clin Med 2020

Covid-19
Delirium
Hospitalised
Management
Older people

"It should not be that difficult to manage a condition that is so frequent": A qualitative study on hospital nurses' experience of delirium guidelines Emme, C. J Clin Nurs 2020

Adult
Delirium/ nursing
Disease Management
Female
Focus Groups
Guideline Adherence
Health Knowledge, Attitudes, Practice
Humans
Male
Middle Aged
Nursing Staff, Hospital/ organization & administration/psychology
Qualitative Research
barriers
clinical guidelines
delirium
evidence-based practice
hospitalised patients
interviews
nursing

Where should patients with or at risk of delirium be treated in an acute care system? Comparing the rates of delirium in patients receiving usual care versus alternative care: a systematic review and meta-analysis Ekeozor, C. U. Jeyaruban, D. Lasserson, D. Int J Clin Pract 2020

Acute care
Comparing, Usual care
Delirium
Hospitalised patients
Interventions
Prevention
Systematic review

Effect of General Versus Spinal Anesthesia on Postoperative Delirium and Early Cognitive Dysfunction in Elderly Patients Ehsani, R. Djalali Motlagh, S. Zaman, B. Sehat Kashani, S. Ghodraty, M. R. Anesth Pain Med 2020

Delirium
General Anesthesia
Pocd
Spinal Anesthesia

Anticholinergic Drug Burden and Delirium: A Systematic Review Egberts, A. Moreno-Gonzalez, R. Alan, H. Ziere, G. Mattace-Raso, F. U. S. Journal of the American Medical Directors Association 2020

adult
Cinahl
Cochrane Library
delirium
Embase
female
follow up
human
male
Medline
PsycINFO
review
scoring system
summer
systematic review
Web of Science
cholinergic receptor blocking agent

Antipsychotics and Lorazepam During Delirium: Are We Harming Older Patients? A Real-Life Data Study Egberts, A. Alan, H. Ziere, G. Mattace-Raso, F. U. S. Drugs and Aging 2020

acutely ill patient
aged
article
controlled study
delirium
drug combination
drug therapy
female
hospital mortality
hospitalization
human
incidence
institutionalization
major clinical study
male
medical record review
prescription
retrospective study
risk assessment
very elderly
lorazepam
neuroleptic agent

Delirium in Internal Medicine Departments in a Tertiary Hospital in Israel: Occurrence, Detection Rates, Risk Factors, and Outcomes Efraim, N. T. Zikrin, E. Shacham, D. Katz, D. Makulin, E. Barski, L. Zeller, L. Bartal, C. Freud, T. Lebedinski, S. Press, Y. Front Med (Lausanne) 2020

delirium
detection rate
occurence
outcomes
risk facors

Development and validation of an aetiology in delirium diagnostic support tool Eeles, E. Huang, L. Dakin, L. Ling, C. Dunn, E. Fraser, J. Dissanayaka, N. N. Age Ageing 2020

aetiology
algorithm
delirium
diagnosis
differential
older people

Association of Geriatric Events With Perioperative Outcomes After Elective Inpatient Surgery Dworsky, J. Q. Shellito, A. D. Childers, C. P. Copeland, T. P. Maggard-Gibbons, M. Tan, H. J. Saliba, D. Russell, M. M. J Surg Res 2020

Elderly
Elective surgery
Frailty
Geriatric events
Geriatric surgery
Older adults

Is there an association between subjective sleep quality and daily delirium occurrence in critically ill adults? A post hoc analysis of a randomised controlled trial Duprey, M. S. Devlin, J. W. Skrobik, Y. BMJ Open Respir Res 2020

clinical epidemiology

Approaches to Optimize Medication Data Analysis in Clinical Cohort Studies Duprey, M. S. Devlin, J. W. Briesacher, B. A. Travison, T. G. Griffith, J. L. Inouye, S. K. J Am Geriatr Soc 2020

delirium
medication
older adults
pharmacoepidemiology
research methods

Delirium definition influences prediction of functional survival in patients one-year postcardiac surgery Dubiel, C. Hiebert, B. M. Stammers, A. N. Sanjanwala, R. M. Tangri, N. Singal, R. K. Manji, R. A. Rudolph, J. L. Arora, R. C. J Thorac Cardiovasc Surg 2020

cardiac surgery
delirium
functional decline
postoperative outcomes

Prevalence and outcome of delirium among acute general medical inpatients in Cape Town, South Africa Du Plooy, N. Day, C. Manning, K. Abdullah, F. James, K. Grace, L. Vorajee, N. April, C. Peter, J. Peter, J. Raubenheimer, P. J. South African Medical Journal 2020

indwelling urinary catheter
creatinine
hemoglobin
potassium
sodium
urea
adult
aphasia
article
cardiovascular disease
central nervous system disease
cognitive defect
cohort analysis
confusion assessment method
delirium
depression
DSM-IV
female
Glasgow coma scale
hearing impairment
heart failure
hospital admission
hospital mortality
hospital patient
hospital readmission
human
Human immunodeficiency virus infection
ICD-10
immobility
interview
length of stay
leukocyte count
major clinical study
male
moderate renal impairment
mortality
neurologic disease
observational study
respiratory failure
risk factor
urea blood level

Delirium Post-Stroke-Influence on Post-Stroke Dementia (Research Study-Part of the PROPOLIS Study) Droś, J. Kowalska, K. Pasińska, P. Szyper-Maciejowska, A. Gorzkowska, A. Klimkowicz-Mrowiec, A. J Clin Med 2020

cognitive impairment
post-stroke delirium
post-stroke dementia
stroke

Providing Evidence-Based Care, Day and Night: A Quality Improvement Initiative to Improve Intensive Care Unit Patient Sleep Quality Douglas, S. L. Hobbs, H. A. Sibley, S. R. Digby, G. C. J Intensive Care Med 2020

critical care
nursing care
quality improvement
sleep

An Implementation-Effectiveness Study of a Perioperative Delirium Prevention Initiative for Older Adults Donovan, A. L. Braehler, M. R. Robinowitz, D. L. Lazar, A. A. Finlayson, E. Rogers, S. Douglas, V. C. Whitlock, E. L. Anesth Analg 2020

Aged
Electronic Health Records/ standards
Emergence Delirium/etiology/ prevention & control
Female
Humans
Male
Perioperative Care/methods/ standards
Practice Guidelines as Topic/ standards
Treatment Outcome

Effectiveness of a multidisciplinary comprehensive intervention model based on the Hospital Elderly Life Program to prevent delirium in patients with severe acute pancreatitis Dong, Z. Song, J. Ge, M. Lin, C. Zhang, J. Chen, J. Wu, Y. Ann Palliat Med 2020

Pancreatitis
aged
cognitive function
delirium
geriatric nursing
self-care

Does Preoperative Comprehensive Geriatric Assessment and Frailty Predict Postoperative Complications? Dogrul, R. T. Dogrul, A. B. Konan, A. Caglar, O. Sumer, F. Caliskan, H. Kizilarslanoglu, M. C. Kilic, M. K. Balci, C. Arik, G. Aycicek, G. S. Ozsurekci, C. Halil, M. Cankurtaran, M. Yavuz, B. B. World journal of surgery 2020

aged
anesthesiologist
article
Charlson Comorbidity Index
complication
controlled study
delirium
female
frailty
geriatric assessment
Geriatric Depression Scale
human
Katz index
major clinical study
male
Mini Mental State Examination
morbidity
mortality
nutritional assessment
postoperative complication
preoperative evaluation
surgery
systolic blood pressure

Preoperative Acute Pain Is Associated with Postoperative Delirium Ding, X. Gao, X. Chen, Q. Jiang, X. Li, Y. Xu, J. Qin, G. Lu, S. Huang, D. Pain Med 2020

C-Reactive Protein
Postoperative Delirium
Preoperative Pain

Effects of electroencephalography and regional cerebral oxygen saturation monitoring on perioperative neurocognitive disorders: a systematic review and meta-analysis Ding, L. Chen, D. X. Li, Q. BMC Anesthesiol 2020

Electroencephalography
Perioperative neurocognitive disorders
Postoperative cognitive decline
Postoperative delirium
Regional cerebral oxygen saturation

The Addition of Intravenous Propofol and Ketorolac to a Sevoflurane Anesthetic Lessens Emergence Agitation in Children Having Bilateral Myringotomy with Tympanostomy Tube Insertion: A Prospective Observational Study d'Eon, B. Hackmann, T. Wright, A. S. Children (Basel) 2020

emergence agitation
ketorolac
myringotomy
pediatric
propofol
sevoflurane

Preoperative Nutritional Status and Risk for Subsyndromal Delirium in Older Adults Following Joint Replacement Surgery Denny, D. L. Trotter, T. Lindseth, G. Orthopedic nursing 2020

aged
article
cognition
controlled study
correlational study
delirium
female
human
major clinical study
male
nutritional assessment
nutritional status
preoperative evaluation
prevention
replacement arthroplasty
risk assessment

Non-pharmacological interventions to reduce the incidence and duration of delirium in critically ill patients: A systematic review and network meta-analysis Deng, L. X. Cao, L. Zhang, L. N. Peng, X. B. Zhang, L. J Crit Care 2020

Delirium prevention
Intensive care unit
Network meta-analysis
Non-pharmacological interventions

Multidimensional nursing interventions effect on delirium and hospital admission duration Dehghani, S. Asadizaker, M. Adineh, M. Maraghi, E. Akbarian, S. Ramezani, B. International Journal of Pharmaceutical and Phytopharmacological Research 2020

IRCT20181005041233N1
adult
article
controlled study
coronary care unit
delirium
disease duration
emergency ward
female
hospital admission
hospitalization
human
major clinical study
male
middle aged
Mini Mental State Examination
nursing intervention
prevalence
randomized controlled trial

Effects of pain, sedation and delirium monitoring on clinical and economic outcome: A retrospective study Deffland, M. Spies, C. Weiss, B. Keller, N. Jenny, M. Kruppa, J. Balzer, F. PLoS ONE 2020

NCT02265263
adult
aged
article
artificial ventilation
clinical effectiveness
clinical evaluation
clinical outcome
cohort analysis
controlled study
delirium
disease severity
economics
female
Germany
hospital admission
hospital discharge
human
intensive care unit
length of stay
machine learning
major clinical study
male
observational study
pain
patient compliance
reimbursement
retrospective study
sedation

The association of post-operative delirium with health-related quality of life and mortality after lung transplantation DeBolt, C. Gao, Y. Sutter, N. Soong, A. Trinh, B. N. Kukreja, J. Kleinhenz, M. Venado, A. Leard, L. E. Hays, S. Greenland, J. R. Shah, R. J. Douglas, V. Kolaitis, N. A. Diamond, J. M. Smith, P. J. Singer, J. P. American Journal of Respiratory and Critical Care Medicine 2020

adult
conference abstract
controlled study
depression
female
gender
human
human tissue
intensive care unit
Kaplan Meier method
lung disease
lung transplantation
major clinical study
male
medical record
mixed cell culture
mortality risk
postoperative delirium
primary graft dysfunction
quality of life
Short Form 12
surgery

Development and validation of a delirium risk prediction preoperative model for cardiac surgery patients (DELIPRECAS): An observational multicentre study de la Varga-Martínez, O. Gómez-Pesquera, E. Muñoz-Moreno, M. F. Marcos-Vidal, J. M. López-Gómez, A. Rodenas-Gómez, F. Ramasco, F. Álvarez-Refojo, F. Tamayo, E. Gómez-Sánchez, E. J Clin Anesth 2020

Cardiac surgery
Delirium
Prevention
Risk factors

The Effect of Multiple Assessments on Delirium Detection: a Pilot Study de Freitas, S. A. Wong, E. Lee, J. Y. Reppas-Rindlisbacher, C. Gabor, C. Curkovic, A. Patterson, C. J. Can Geriatr J 2020

3d-cam
delirium
multiple observations
orthopedic
point-prevalence

Delirium Detection Based on the Clinical Experience of Pediatric Intensivists de Castro, R. E. V. de Magalhães-Barbosa, M. C. Cunha, Ajlad Cheniaux, E. Prata-Barbosa, A. Pediatr Crit Care Med 2020
Kidney Function Modifies the Effect of Intraoperative Opioid Dosage on Postoperative Delirium Davani, A. B. Snyder, S. H. Oh, E. S. Mears, S. C. Crews, D. C. Wang, N. Y. Sieber, F. E. J Am Geriatr Soc 2020

analgesics, opioids
delirium, postoperative
hip fracture
kidney

One-year mortality rate after fragility hip fractures and associated risk in Nan, Thailand Daraphongsataporn, N. Saloa, S. Sriruanthong, K. Philawuth, N. Waiwattana, K. Chonyuen, P. Pimolbutr, K. Sucharitpongpan, W. Osteoporosis and Sarcopenia 2020

aged
article
cohort analysis
delirium
electronic medical record
end stage renal disease
female
fragility fracture
health statistics
hip fracture
hospital discharge
human
major clinical study
male
medical record review
mortality rate
pneumonia
retrospective study
risk factor
Thailand

Abnormal Sleep, Circadian Rhythm Disruption, and Delirium in the ICU: Are They Related? Daou, M. Telias, I. Younes, M. Brochard, L. Wilcox, M. E. Front Neurol 2020

ICU acquired delirium
circadian rhythm
intervention
mechanisms
sleep

Delirium prevention and treatment in the emergency department (ED): a systematic review protocol Dahlstrom, E. B. Han, J. H. Healy, H. Kennedy, M. Arendts, G. Lee, J. Carpenter, C. Lee, S. BMJ Open 2020

accident & emergency medicine
delirium & cognitive disorders
geriatric medicine

Pathomechanisms of Non-Traumatic Acute Brain Injury in Critically Ill Patients Dabrowski, W. Siwicka-Gieroba, D. Gasinska-Blotniak, M. Zaid, S. Jezierska, M. Pakulski, C. Williams Roberson, S. Wesley Ely, E. Kotfis, K. Medicina (Kaunas) 2020

critical illness
delirium
gastrointestinal microbiome
hyperoxia
hypoxia
kynurenine pathway
neuroinflammation
neurotransmitter agents
tryptophan

Low molecular weight heparin in COVID-19 patients prevents delirium and shortens hospitalization D’Ardes, D. Carrarini, C. Russo, M. Dono, F. Speranza, R. Digiovanni, A. Martinotti, G. Di Iorio, A. Onofrj, M. Cipollone, F. Bonanni, L. Neurological Sciences 2020

adult
article
cognitive defect
cohort analysis
comorbidity
complication
controlled study
coronavirus disease 2019
drug therapy
female
hospitalization
human
intensive care unit
length of stay
major clinical study
male
prevention
C reactive protein
endogenous compound
enoxaparin

Postoperative delirium: why, what, and how to confront it at your institution Curtis, M. S. Forman, N. A. Donovan, A. L. Whitlock, E. L. Curr Opin Anaesthesiol 2020

Aged
Delirium/ prevention & control
Humans
Perioperative Care
Postoperative Complications

Delirium due to intoxication with quetiapine: A systematic literature review Crombez, S. van Den Wijngaert, V. Demyttenaere, K. de Fruyt, J. Tijdschrift voor Psychiatrie 2020

physostigmine
quetiapine
agitation
article
delirium
drug intoxication
human
incidence
systematic review

Postoperative delirium in patients with head and neck oral cancer in the West of Scotland Crawford, J. E. Zubair, F. Baniulyte, G. Wales, C. J. Ansell, M. Thomson, E. Hislop, S. MacIver, C. Devine, J. McCaul, J. Young, D. McMahon, J. Br J Oral Maxillofac Surg 2020

Eras
Head and neck
delirium
free flap
oral cancer
postoperative care

Diagnosis, prevention, and management of delirium in the intensive cardiac care unit Cortés-Beringola, A. Vicent, L. Martín-Asenjo, R. Puerto, E. Domínguez-Pérez, L. Maruri, R. Moreno, G. Vidán, M. T. Fernando, Arribas Bueno, H. Am Heart J 2020
Serum DBI and biomarkers of neuroinflammation in Alzheimer's disease and delirium Conti, E. Andreoni, S. Tomaselli, D. Storti, B. Brovelli, F. Acampora, R. Da Re, F. Appollonio, I. Ferrarese, C. Tremolizzo, L. Neurol Sci 2020

Alzheimer’s disease
Cytokines
Delirium
Diazepam binding inhibitor
Monocytes
Serum

A complication of coronavirus disease 2019: delirium Cipriani, G. Danti, S. Nuti, A. Carlesi, C. Lucetti, C. Di Fiorino, M. Acta Neurol Belg 2020

Betacoronavirus
Covid-19
Coronavirus Infections/ complications
Delirium/ virology
Humans
Pandemics
Pneumonia, Viral/ complications
SARS-CoV-2
Delirium
Dementia
Intensive-care unit

Post-operative delirium and cognitive decline in kidney transplantation Chu, N. M. Chen, X. Segev, D. L. McAdams-DeMarco, M. Journal of the American Society of Nephrology 2020

adult
cognitive defect
cohort analysis
conference abstract
controlled study
executive function
female
human
kidney transplantation
major clinical study
male
medical record
memory
nephrologist
postoperative delirium

Vitamin D and Delirium in Older Adults: A Case-Control Study in Geriatric Acute Care Unit Chouët, J. Sacco, G. Karras, S. N. Llewellyn, D. J. Sánchez-Rodríguez, D. Annweiler, C. Front Neurol 2020

cognition
delirium
neuroendocrinology
older adults
vitamin D

Risk factors for postoperative delirium in elderly patients after spinal fusion surgery Choi, S. Jung, I. Yoo, B. Lee, S. Kim, M. C. Anesth Pain Med (Seoul) 2020

Aged
Anesthesia, general
Delirium
Postoperative complication
Risk factors
Spinal, surgery

Multimodal Education Program to Improve Nurses' Knowledge and Confidence on Delirium Recognition in a Surgical-Trauma Intermediate-Care Setting Choi, M. DeGennaro, R. Blevins, C. Journal of doctoral nursing practice 2020

adult
article
controlled study
delirium
education program
human
intermediate care unit
learning
nurse
nursing unit
pretest posttest design
simulation
surgical injury
university hospital
videorecording

Development and validation of delirium prediction model for critically ill adults parameterized to ICU admission acuity Cherak, S. J. Soo, A. Brown, K. N. Ely, E. W. Stelfox, H. T. Fiest, K. M. PLoS One 2020

Apache
Adult
Aged
Critical Illness
Decision Support Techniques
Delirium/ diagnosis
Female
Hospitalization/ statistics & numerical data
Humans
Intensive Care Units/ statistics & numerical data
Male
Middle Aged
Prospective Studies
ROC Curve
Retrospective Studies
Risk Factors

Association of Glucose Variability and ICU Delirium of Patients after Liver Transplantation Cheng, J. L. Dong, M. L. Zhang, Z. W. Liao, X. L. Yang, J. Y. Kang, Y. Journal of Sichuan University. Medical science edition 2020

adverse event
cohort analysis
delirium
glucose blood level
human
intensive care unit
liver transplantation
retrospective study
risk factor

Modified Frailty Index Independently Predicts Postoperative Delirium and Delayed Neurocognitive Recovery After Elective Total Joint Arthroplasty Chen, Y. Qin, J. J Arthroplasty 2020

delayed neurocognitive recovery
delirium
modified frailty index
osteoarthritis
total joint arthroplasty

Risk predictive models for delirium in the intensive care unit: a systematic review and meta-analysis Chen, X. Lao, Y. Zhang, Y. Qiao, L. Zhuang, Y. Ann Palliat Med 2020

Delirium
intensive care units
meta-analysis
prediction model

Diagnostic accuracy of the CAM-ICU and ICDSC in detecting intensive care unit delirium: A bivariate meta-analysis Chen, T. J. Chung, Y. W. Chang, H. C. R. Chen, P. Y. Wu, C. R. Hsieh, S. H. Chiu, H. Y. International journal of nursing studies 2020

adult
artificial ventilation
checklist
Cinahl
critically ill patient
diagnostic accuracy
diagnostic test accuracy study
Embase
female
human
intensive care psychosis
medical intensive care unit
Medline
meta analysis
outpatient
patient selection
review
sensitivity and specificity
standard
systematic review

Atypical Sleep and Postoperative Delirium in the Cardiothoracic Surgical Intensive Care Unit: A Pilot Prospective Study Chen, Q. Peng, Y. Lin, Y. Li, S. Huang, X. Chen, L. W. Nat Sci Sleep 2020

atypical sleep
cardiac surgery
intensive care unit
postoperative delirium

Delirium risk prediction models for intensive care unit patients: A systematic review Chen, J. Yu, J. Zhang, A. Intensive Crit Care Nurs 2020

Delirium
Icu
Prediction model
Systematic review

The role of statins in the management of delirium: Recent advances Chen, J. Wang, Y. Hu, X. Li, M. Xiong, K. Zhang, Z. Chen, Q. CNS Neurol Disord Drug Targets 2020

Delirium
cerebral hypoperfusion
microthrombosis
neurotransmitters
statins
systemic neuroinflammation

Analysis of Risk Factors for Postoperative Delirium After Liver Transplantation Chen, J. Wang, H. He, Z. Li, T. Neuropsychiatr Dis Treat 2020

ammonia
hepatic encephalopathy
liver transplantation
postoperative delirium
risk factors

Analgesia and sedation in patients with ARDS Chanques, G. Constantin, J. M. Devlin, J. W. Ely, E. W. Fraser, G. L. Gélinas, C. Girard, T. D. Guérin, C. Jabaudon, M. Jaber, S. Mehta, S. Langer, T. Murray, M. J. Pandharipande, P. Patel, B. Payen, J. F. Puntillo, K. Rochwerg, B. Shehabi, Y. Strøm, T Intensive Care Med 2020

Analgesia/methods/ standards
Guidelines as Topic
Humans
Hypnotics and Sedatives/ therapeutic use
Pain Management/methods
Respiratory Distress Syndrome/ drug therapy
Acute respiratory distress syndrome
Analgesia
Covid-19
Intensive care unit
Mechanical ventilation
Rehabilitation
Sedation

Delirium Prevention, Detection, and Treatment in Emergency Medicine Settings: A Geriatric Emergency Care Applied Research (GEAR) Network Scoping Review and Consensus Statement Carpenter, C. R. Hammouda, N. Linton, E. A. Doering, M. Ohuabunwa, U. K. Ko, K. J. Hung, W. W. Shah, M. N. Lindquist, L. A. Biese, K. Wei, D. Hoy, L. Nerbonne, L. Hwang, U. Dresden, S. M. Academic Emergency Medicine 2020

aged
applied research
article
consensus
controlled study
delirium
education
emergency care
emergency medicine
emergency physician
emergency ward
female
geriatrician
gestalt psychology
human
intervention study
librarian
male
meta analysis
nurse
pharmacist
phenotype
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
prevalence
prevention
prevention study
randomized controlled trial (topic)
sensitivity and specificity
social worker
systematic review

Geriatric emergency care applied research network cognitive impairment priorities consensus conference Carpenter, C. R. Hammouda, N. Linton, E. Doerring, M. Ohuabunwa, U. Ko, K. Hung, W. Dresden, S. M. Shah, M. N. Lindquist, L. Biese, K. Wei, D. Hwang, U. Academic Emergency Medicine 2020

adult
aging
applied research
care bundle
clinical assessment
cognitive defect
conference abstract
controlled study
diagnostic accuracy
diagnostic test accuracy study
emergency care
emergency medicine
emergency ward
female
geriatrics
human
implementation science
incidence
intensive care
language
leadership
length of stay
librarian
male
multicenter study (topic)
nurse
pharmacy (discipline)
phenotype
physician
pilot study
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
prevention
psychology
randomized controlled trial (topic)
research priority
social work
systematic review
workload

Identifying and Responding to Delirium in Acute Stroke: Clinical Team Members' Understandings Carin-Levy, G. Nicol, K. van Wijck, F. Mead, G. McVittie, C. Qualitative health research 2020

adult
article
clinical article
controlled study
delirium
female
grounded theory
human
interview
male
nurse
occupational therapist
physiotherapist
Scotland
speech language pathologist
stroke survivor
stroke unit
vignette

Antipsychotic use in the prevention and treatment of intensive care unit delirium in pediatric patients Capino, A. C. Thomas, A. N. Baylor, S. Hughes, K. M. Miller, J. L. Johnson, P. N. Journal of Pediatric Pharmacology and Therapeutics 2020

haloperidol
midazolam
neuroleptic agent
olanzapine
quetiapine
risperidone
child
consciousness disorder
drug efficacy
dystonia
extrapyramidal symptom
fever
human
hyperpyrexia
hypersalivation
intensive care psychosis
muscle rigidity
oculogyric crisis
QT prolongation
review
tachycardia
tremor

Screening instruments for cognitive impairment in older patients in the Emergency Department: a systematic review and meta-analysis Calf, A. H. Pouw, M. A. van Munster, B. C. Burgerhof, J. G. M. de Rooij, S. E. Smidt, N. Age Ageing 2020

Emergency Department
cognitive impairment
delirium
dementia
older people
screening

Prevalence, Predictors, and Early Outcomes of Post-operative Delirium in Patients With Type A Aortic Dissection During Intensive Care Unit Stay Cai, S. Zhang, X. Pan, W. Latour, J. M. Zheng, J. Zhong, J. Gao, J. Lv, M. Luo, Z. Wang, C. Zhang, Y. Front Med (Lausanne) 2020

delirium
early outcomes
incidence
risk factors
type A aortic dissection

Toxin-Induced Acute Delirium Cai, A. Cai, X. Neurol Clin 2020

Anticholinergic
Delirium
GABA withdrawal
Hallucinogen
Sympathomimetic
Toxidrome
Wernicke

Cognitive and psychosocial outcomes of mechanically ventilated intensive care patients with and without delirium Bulic, D. Bennett, M. Georgousopoulou, E. N. Shehabi, Y. Pham, T. Looi, J. C. L. van Haren, F. M. P. Ann Intensive Care 2020

Cognition
Delirium
Intensive care
Long-term outcomes
Post-traumatic stress disorder
Psychosocial function

The influence of a serious game's narrative on students' attitudes and learning experiences regarding delirium: an interview study Buijs-Spanjers, K. R. Harmsen, A. Hegge, H. H. Spook, J. E. de Rooij, S. E. Jaarsma, Dadc BMC Med Educ 2020

Delirium
Education
Narrative
Serious game

Preoperative prognostic factors associated with postoperative delirium in older people undergoing surgery: protocol for a systematic review and individual patient data meta-analysis Buchan, T. A. Sadeghirad, B. Schmutz, N. Goettel, N. Foroutan, F. Couban, R. Mbuagbaw, L. Dodsworth, B. T. Syst Rev 2020

Elderly
Individual patient data meta-analysis
Postoperative
Prognostic factors

Impact of Therapeutic Music Listening on Intensive Care Unit Patients: A Pilot Study Browning, S. G. Watters, R. Thomson-Smith, C. Nurs Clin North Am 2020

Aged
Critical Illness/psychology/ therapy
Delirium/psychology/therapy
Female
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Middle Aged
Music Therapy/methods/ standards/trends
Pilot Projects
Intensive care unit (ICU) delirium
Mechanical ventilation
Therapeutic music listening