Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Comparison of Esophagectomy outcomes between a National Center, a National Audit Collaborative, and an International database using the Esophageal Complications Consensus Group (ECCG) standardized definitions
Authors
Reynolds, J. V. Donlon, N. Elliott, J. A. Donohoe, C. Ravi, N. Kuppusamy, M. K. Low, D. E.
Year
2021
Journal
Dis Esophagus
Abstract

The ECCG developed a standardized platform for reporting operative complications, with consensus definitions. The Dutch Upper Gastrointestinal Cancer Audit (DUCA) published a national comparison against these benchmarks. This study compares ECCG data from the Irish National Center (INC) with both published benchmark studies. All patients undergoing multimodal therapy or surgery with curative intent from 2014 to 2018 inclusive were studied, with data recorded prospectively and entered onto a secure online database (Esodata.org). 219 patients (mean age 67; 77% male) underwent open resection, 66.6% via transthoracic en bloc resection. 30-day and 90-day mortality were 0.0 and 0.9%,nrespectively. Anastomotic leak rate was 5.4%, pneumonia 18.2%, respiratory failure 10%, ARDS 2.7%, atrial dysrhythmia 22.8%, recurrent nerve injury 3%, and delirium in 5% of patients. Compared with both ECCG and DUCA, where MIE constituted 47 and 86% of surgical approaches, respectively, overall complications were similar, as were severity of complications; however, anastomotic leak rate was several-fold less, and mortality was significantly lower (P < 0.001). In this consecutive series and comparative audit with benchmark averages from the ECCG and DUCA publications, a low mortality and anastomotic leak rate were the key differential findings. Although not risk stratified, the severity of complications from this ‘open’ series is consistent with series containing large numbers of total or hybrid MIE, highlighting a need to adhere to these strictly defined definitions in further prospective research and randomized studies.

PMID

32591791

Keywords

Aged
Anastomotic Leak/epidemiology/etiology
Consensus
*Esophageal Neoplasms/surgery
*Esophagectomy/adverse effects
Female
Humans
Male
Postoperative Complications/epidemiology/etiology
Retrospective Studies
complications
esophageal cancers
esophagectomy

Page(s)
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Preoperative Cognitive Impairment and the Prevalence of Postoperative Delirium in Elderly Cancer Patients-A Prospective Observational Study Ristescu, A. I. Pintilie, G. Moscalu, M. Rusu, D. Grigoras, I. Diagnostics (Basel) 2021

Mini-Cog test
Nu-DESC score
elderly patients
postoperative delirium
preoperative cognitive impairment

Delirium in Patients with SARS-CoV-2 Infection: A Multicenter Study Rebora, P. Rozzini, R. Bianchetti, A. Blangiardo, P. Marchegiani, A. Piazzoli, A. Mazzeo, F. Cesaroni, G. Chizzoli, A. Guerini, F. Bonfanti, P. Morandi, A. Faraci, B. Gentile, S. Bna, C. Savelli, G. Citerio, G. Valsecchi, M. G. Mazzola, P. Bellelli, G. J Am Geriatr Soc 2021

Aged
Aged, 80 and over
COVID-19/ mortality
Cohort Studies
Comorbidity
Delirium/ diagnosis/ mortality
Female
Geriatric Assessment
Hospital Mortality
Humans
Inpatients/ statistics & numerical data
Intensive Care Units
Italy/epidemiology
Male
Prevalence
Risk Factors
Covid-19
delirium
hospital
mortality
older adults

Machine Learning to Develop and Internally Validate a Predictive Model for Post-operative Delirium in a Prospective, Observational Clinical Cohort Study of Older Surgical Patients Racine, A. M. Tommet, D. D'Aquila, M. L. Fong, T. G. Gou, Y. Tabloski, P. A. Metzger, E. D. Hshieh, T. T. Schmitt, E. M. Vasunilashorn, S. M. Kunze, L. Vlassakov, K. Abdeen, A. Lange, J. Earp, B. Dickerson, B. C. Marcantonio, E. R. Steingrimsson, J. Travi J Gen Intern Med 2021

Aged
Cohort Studies
Delirium/diagnosis/epidemiology
Humans
Logistic Models
Machine Learning
Prospective Studies
delirium
model prediction
post-operative
statistical learning

Low Vitamin D Levels and Risk of Incident Delirium in 351,000 Older UK Biobank Participants Pilling, L. C. Jones, L. C. Masoli, J. A. H. Delgado, J. Atkins, J. L. Bowden, J. Fortinsky, R. H. Kuchel, G. A. Melzer, D. J Am Geriatr Soc 2021

biomarker
delirium
genetic
risk factor
vitamin D

Delirium in older adults is associated with development of new dementia: a systematic review and meta-analysis Pereira, J. V. Aung Thein, M. Z. Nitchingham, A. Caplan, G. A. Int J Geriatr Psychiatry 2021

delirium
dementia
meta-analysis
older adults
systematic review

Mortality and Medical Complications of Subtrochanteric Fracture Fixation Panteli, M. Giannoudi, M. P. Lodge, C. J. West, R. M. Pountos, I. Giannoudis, P. V. J Clin Med 2021

complications
hip fractures
mortality
subtrochanteric

Predicting Delirium Risk Using an Automated Mayo Delirium Prediction Tool: Development and Validation of a Risk-Stratification Model Pagali, S. R. Miller, D. Fischer, K. Schroeder, D. Egger, N. Manning, D. M. Lapid, M. I. Pignolo, R. J. Burton, M. C. Mayo Clin Proc 2021

Aged
Aged, 80 and over
Clinical Decision Rules
Delirium/ diagnosis/ etiology
Female
Health Status Indicators
Hospitalization
Humans
Logistic Models
Male
Middle Aged
Reproducibility of Results
Retrospective Studies
Risk Assessment
Risk Factors

Effectiveness of Quetiapine as a Sedative Adjunct in Mechanically Ventilated Adults Without Delirium Ohman, K. L. Schultheis, J. M. Kram, S. J. Cox, C. E. Gilstrap, D. L. Yang, Z. Kram, B. L. Ann Pharmacother 2021

Adjuvants, Pharmaceutic/administration & dosage/ therapeutic use
Adult
Analgesics, Opioid/administration & dosage/therapeutic use
Benzodiazepines/administration & dosage/therapeutic use
Cohort Studies
Delirium
Dexmedetomidine/administration & dosage/therapeutic use
Dose-Response Relationship, Drug
Female
Humans
Hypnotics and Sedatives/administration & dosage/ therapeutic use
Intensive Care Units
Male
Middle Aged
Pain/drug therapy
Propofol/administration & dosage/therapeutic use
Quetiapine Fumarate/ therapeutic use
Respiration, Artificial
Retrospective Studies
antipsychotics
antipsychotics (atypical)
critical care
mechanical
sedatives
ventilators

Development of a postoperative delirium risk scoring tool using data from the Australian and New Zealand Hip Fracture Registry: an analysis of 6672 patients 2017-2018 Oberai, T. Oosterhoff, J. H. F. Woodman, R. Doornberg, J. N. Kerkhoffs, G. Jaarsma, R. Arch Gerontol Geriatr 2021

Aged, 80 and over
Australia/epidemiology
Delirium/diagnosis/epidemiology/etiology
Hip Fractures/epidemiology/surgery
Humans
Male
New Zealand/epidemiology
Postoperative Complications/epidemiology/etiology
Registries
Risk Factors
Tool Use Behavior
Delirium
hip fractures
multivariate
risk score

Does implementation of a tailored intervention increase adherence to a National Safety and Quality Standard? A study to improve delirium care Oberai, T. Laver, K. Woodman, R. Crotty, M. Kerkhoffs, G. Jaarsma, R. Int J Qual Health Care 2021

elderly
health policy
hospital care
quality improvement
standards

Delirium in Burn Patients: Developing a Mobile Application for Assessment and Diagnosis Mohseni Moallem Kolaei, N. Ayatollahi, H. Elyasi, F. J Burn Care Res 2021
Combination of delirium and coma predicts psychiatric symptoms at twelve months in critically ill patients: A longitudinal cohort study Miyamoto, K. Shibata, M. Shima, N. Nakashima, T. Kida, M. Matsumoto, H. Oka, N. Yazaki, A. Uchigaki, A. Takemoto, A. Kato, S. J Crit Care 2021

Activity of daily living disability
Coma
Delirium
Post intensive care syndrome
Psychiatric symptoms

Implementation of the Family HELP Protocol: A Feasibility Project for a West Texas ICU McClay, R. Healthcare (Basel) 2021

Icu
bedside nurse
critical care
delirium
family HELP
hospital elder life program

Prevention and Management of Delirium in the Intensive Care Unit Mart, M. F. Williams Roberson, S. Salas, B. Pandharipande, P. P. Ely, E. W. Semin Respir Crit Care Med 2021
Haloperidol for preventing delirium in ICU patients: a systematic review and meta-analysis Marra, A. Vargas, M. Buonanno, P. Iacovazzo, C. Kotfis, K. Servillo, G. Eur Rev Med Pharmacol Sci 2021

Delirium
Disorders
Factors
Prospective
Trauma

Delirium in trauma patients: a 1-year prospective cohort study of 2026 patients Marquetand, J. Gehrke, S. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Känel, R. Boettger, S. Eur J Trauma Emerg Surg 2021

Delirium
Disorders
Factors
Prospective
Trauma

Subsyndromal Delirium in Cardiac Surgery Patients: Risk Factors and Outcomes of the Different Trajectories Mailhot, T. Cossette, S. Maheu-Cadotte, M. A. Fontaine, G. Denault, A. Y. J Cardiovasc Nurs 2021
Low-Dose Trazodone for Delirium in Patients with Cancer Who Received Specialist Palliative Care: A Multicenter Prospective Study Maeda, I. Inoue, S. Uemura, K. Tanimukai, H. Hatano, Y. Yokomichi, N. Amano, K. Tagami, K. Yoshiuchi, K. Ogawa, A. Iwase, S J Palliat Med 2021

cancer
delirium
palliative care units
psycho-oncology
trazodone

Preoperative anxiety predicted the incidence of postoperative delirium in patients undergoing total hip arthroplasty: a prospective cohort study Ma, J. Li, C. Zhang, W. Zhou, L. Shu, S. Wang, S. Wang, D. Chai, X. BMC Anesthesiol 2021

Anxiety
Cognitive ability
Delirium
Hip surgery

Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study Likhvantsev, V. V. Landoni, G. Grebenchikov, O. A. Ovezov, A. M. Skripkin, Y. V. Lembo, R. Gaevskiy, D. I. Tereshina, A. A. Yavorovskiy, A. G. J Cardiothorac Vasc Anesth 2021

Adult
Cardiac Surgical Procedures/adverse effects
Delirium/epidemiology/prevention & control
Dexmedetomidine
Double-Blind Method
Humans
Hypnotics and Sedatives/adverse effects
Incidence
anesthesia
cardiac surgery
cardiopulmonary bypass
outcomes
postoperative delirium

An observational study of hypoactive delirium in the post-anesthesia recovery unit of a pediatric hospital Lee-Archer, P. F. von Ungern-Sternberg, B. S. Reade, M. C. Law, K. C. Long, D. Paediatr Anaesth 2021

emergence delirium
pediatrics
postoperative complications

A prospective observational cohort pilot study of the association between midazolam use and delirium in elderly endoscopy patients Lee, D. Petersen, F. Wu, M. Chapman, G. Hayman, M. Tomkins, K. Fernando, J. BMC Anesthesiol 2021

Anaesthesia
Delirium
Elderly
Endoscopy
Midazolam
Sedation

Discharge from hospital with newly administered antipsychotics after intensive care unit delirium - Incidence and contributing factors Lambert, J. Vermassen, J. Fierens, J. Peperstraete, H. Petrovic, M. Colpaert, K. J Crit Care 2021

Antipsychotics
Delirium
Haloperidol
Intensive care unit
Polypharmacy
Transitions of care

Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis Hughes, C. G. Mailloux, P. T. Devlin, J. W. Swan, J. T. Sanders, R. D. Anzueto, A. Jackson, J. C. Hoskins, A. S. Pun, B. T. Orun, O. M. Raman, R. Stollings, J. L. Kiehl, A. L. Duprey, M. S. Bui, L. N. O'Neal, H. R., Jr. Snyder, A. Gropper, M. A. Guntupall N Engl J Med 2021

Adult
Cognition/drug effects
Conscious Sedation/ methods
Critical Illness
Dexmedetomidine/administration & dosage
Double-Blind Method
Humans
Hypnotics and Sedatives/administration & dosage/adverse effects
Kaplan-Meier Estimate
Propofol/administration & dosage
Respiration, Artificial
Sepsis/mortality/ therapy

Repeated Preoperative Intranasal Administration of Insulin Decreases the Incidence of Postoperative Delirium in Elderly Patients Undergoing Laparoscopic Radical Gastrointestinal Surgery: A Randomized, Placebo-Controlled, Double-Blinded Clinical Study Huang, Q. Li, Q. Qin, F. Yuan, L. Lu, Z. Nie, H. Gong, G. Am J Geriatr Psychiatry 2021

Postoperative delirium
elderly
insulin
intranasal

The diagnostic threshold of Cornell assessment of pediatric delirium in detection of postoperative delirium in pediatric surgical patients Hong, H. Guo, C. Liu, Z. H. Wang, B. J. Zhou, S. Z. Mu, D. L. Wang, D. X. BMC Pediatr 2021

Child
Child, Preschool
Critical Illness
Delirium/diagnosis
Diagnostic and Statistical Manual of Mental Disorders
Humans
Prospective Studies
Reproducibility of Results
Chinese version
Cornell assessment of pediatric delirium
Pediatric delirium
Surgery
Threshold

Ketamine vs. haloperidol for prevention of cognitive dysfunction and postoperative delirium: A phase IV multicentre randomised placebo-controlled double-blind clinical trial Hollinger, A. Rüst, C. A. Riegger, H. Gysi, B. Tran, F. Brügger, J. Huber, J. Toft, K. Surbeck, M. Schmid, H. R. Rentsch, K. Steiner, L. Siegemund, M. J Clin Anesth 2021

Adult
Cognitive Dysfunction/etiology/prevention & control
Delirium/prevention & control
Double-Blind Method
Haloperidol/adverse effects
Humans
Ketamine
Cortisol
Dos
Mmse
Nse
Nu-DESC
S100β

Delirium care knowledge in critical care nurses: A multiple-choice question-based quiz Ho, M. H. Traynor, V. Chen, K. H. Montayre, J. Lin, Y. K. Chang, H. R. Nurs Crit Care 2021

critical care nursing
delirium
evidence-based practice
instrument development
knowledge

Comparison of hospital course and outcome in hospital-acquired vs pre-existing delirium Guillory, J. Fitz-Gerald, C. Banik, A. Sterwald, C. Ashiofu, E. Knox, E. Muyco, M. A. Verlage, M. Abdali, A. O'Malley, P. W. Rezai, A. Bush, P. Brown, E. S. North, C. S. Ann Clin Psychiatry 2021
Dexmedetomidine reduces postoperative cognitive and behavioral dysfunction in adults submitted to general anesthesia for non-cardiac surgery: meta-analysis of randomized clinical trials Govêia, C. S. Miranda, D. B. Oliveira, L. V. B. Praxedes, F. B. Moreira, L. G. Guimarães, G. M. N. Braz J Anesthesiol 2021

Delirium
Dexmedetomidine
General anesthesia
Meta-analysis
Psychomotor agitation

An exploration of the reliability and usability of two delirium screening tools in an Australian intensive care unit: A pilot study Ewers, R. Bloomer, M. J. Hutchinson, A. Intensive Crit Care Nurs 2021

Confusion assessment methods -ICU
Delirium
Delirium screening tools
Intensive CARE Delirium Screening Checklist
Intensive care units
Nursing assessment

Haloperidol and Quetiapine for the Treatment of ICU-Associated Delirium in a Tertiary Pediatric ICU: A Propensity Score-Matched Cohort Study Cronin, M. T. Di Gennaro, J. L. Watson, R. S. Dervan, L. A. Paediatr Drugs 2021

Antipsychotic Agents/therapeutic use
Child
Cohort Studies
Delirium/ drug therapy
Female
Haloperidol/ administration & dosage/adverse effects
Humans
Intensive Care Units, Pediatric
Male
Propensity Score
Quetiapine Fumarate/ therapeutic use
Respiration, Artificial
Retrospective Studies

Post-operative delirium in older hip fracture patients: a new onset or was it already there? Costa-Martins, I. Carreteiro, J. Santos, A. Costa-Martins, M. Artilheiro, V. Duque, S. Campos, L. Chedas, M. Eur Geriatr Med 2021

Cognitive assessment
Hip fracture
Post-operative delirium
Pre-operative delirium

The Use of Tablet Computers to Reduce Preoperative Anxiety in Children Before Anesthesia: A Randomized Controlled Study Clausen, N. G. Madsen, D. Rosenkilde, C. Hasfeldt-Hansen, D. Larsen, L. G. Hansen, T. G. J Perianesth Nurs 2021

emergence delirium
general anesthesia
pediatric anesthesia
preoperative anxiety

A gap existed between physicians' perceptions and performance of pain, agitation-sedation and delirium assessments in Chinese intensive care units Chen, K. Yang, Y. L. Li, H. L. Xiao, D. Wang, Y. Zhang, L. Zhou, J. X. BMC Anesthesiol 2021

Analgesia
Critical care
Practice
Prevalence
Sedation
Survey

Association of Depressive Symptoms With Postoperative Delirium and CSF Biomarkers for Alzheimer's Disease Among Hip Fracture Patients Chan, C. K. Sieber, F. E. Blennow, K. Inouye, S. K. Kahn, G. Leoutsakos, J. S. Marcantonio, E. R. Neufeld, K. J. Rosenberg, P. B. Wang, N. Y. Zetterberg, H. Lyketsos, C. G. Oh, E. S. Am J Geriatr Psychiatry 2021

Alzheimer’s disease
amyloid
csf
delirium
depression
hip fracture
mild behavioral impairment
tau

Delirium as a predictor of mortality and disability among hospitalized patients in Zambia Banerdt, J. K. Mateyo, K. Wang, L. Lindsell, C. J. Riviello, E. D. Saylor, D. Heimburger, D. C. Ely, E. W. PLoS One 2021
Incidence and Risk Factors of Emergence Delirium after Anesthesia in Elderly Patients at a Postanesthesia Care Unit in Ethiopia: Prospective Observational Study Assefa, M. T. Chekol, W. B. Melesse, D. Y. Nigatu, Y. A. Patient Relat Outcome Meas 2021

delirium
emergence delirium
incidence and associated factors
postanesthesia care

Impact of SARS-CoV-2 Infection on Cognitive Function: A Systematic Review Alnefeesi, Y. Siegel, A. Lui, L. M. W. Teopiz, K. M. Ho, R. C. M. Lee, Y. Nasri, F. Gill, H. Lin, K. Cao, B. Rosenblat, J. D. McIntyre, R. S. Front Psychiatry 2021

Covid-19
brain health
cognitive function
cytokines
delirium
depression
neuroinflammation
neurotropism

Cognitive disorders associated with hospitalization of COVID-19: Results from an observational cohort study Zhou, J. Liu, C. Sun, Y. Huang, W. Ye, K. Brain Behav Immun 2021

Adult
Aged
Angiotensin-Converting Enzyme 2/genetics/metabolism
Biomarkers/blood
COVID-19/ psychology
Cognition
Cognitive Dysfunction/ physiopathology
Cohort Studies
European Continental Ancestry Group/genetics
Female
Hospitalization/ trends
Humans
Male
Middle Aged
Pandemics
Risk Factors
SARS-CoV-2/genetics/metabolism
Serine Endopeptidases/genetics/metabolism
Alzheimer’s disease
Covid-19
Cognitive disorders
Dementia
Pre-existing conditions
Risk factors

Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults Zazzara, M. B. Penfold, R. S. Roberts, A. L. Lee, K. A. Dooley, H. Sudre, C. H. Welch, C. Bowyer, R. C. E. Visconti, A. Mangino, M. Freidin, M. B. El-Sayed Moustafa, J. S. Small, K. S. Murray, B. Modat, M. Graham, M. S. Wolf, J. Ourselin, S. Martin, F. C. Age Ageing 2021

Aged
COVID-19/epidemiology/psychology/therapy
COVID-19 Nucleic Acid Testing/methods/statistics & numerical data
Cohort Studies
Delirium/diagnosis/epidemiology/etiology
Female
Frail Elderly
Frailty/diagnosis/epidemiology/etiology
Geriatric Assessment/methods
Hospitalization/statistics & numerical data
Humans
London/epidemiology
Male
Prevalence
Risk Assessment/ methods
Risk Factors
SARS-CoV-2/ isolation & purification
Covid-19
delirium
frailty
older people

Association between intensive care unit delirium and delusional memory after critical care in mechanically ventilated patients Yoshino, Y. Unoki, T. Sakuramoto, H. Ouchi, A. Hoshino, H. Matsuishi, Y. Mizutani, T. Nurs Open 2021

delirium
delusional memory
intensive care unit
mechanical ventilation

Delirium screening for patients in the intensive care unit: A prospective validation study of the iCAM-ICU by nurse researchers and bedside nurses in routine practice Yang, F. Ji, M. Wu, Y. Feng, Y. Li, J. Ren, D. Ely, E. W. Int J Nurs Stud 2021

Confusion
Delirium assessment
Diagnostic accuracy
Health information technology
Sensitivity and specificity

Six-Minute Walk Test Predicts Postoperative Delirium After Transcatheter Aortic Valve Replacement Yamashita, A. Suzuki, S. Otsuka, T. Matsuda, H. Ando, H. Sugimura, K. Maekawa, E. Meguro, K. Ako, J. Okamoto, H. J Cardiothorac Vasc Anesth 2021

Clinical Frailty Scale
postoperative delirium
six-minute walk test
transcatheter aortic valve replacement

Topological data analysis (TDA) enhances bispectral EEG (BSEEG) algorithm for detection of delirium Yamanashi, T. Kajitani, M. Iwata, M. Crutchley, K. J. Marra, P. Malicoat, J. R. Williams, J. C. Leyden, L. R. Long, H. Lo, D. Schacher, C. J. Hiraoka, K. Tsunoda, T. Kobayashi, K. Ikai, Y. Kaneko, K. Umeda, Y. Kadooka, Y. Shinozaki, G. Sci Rep 2021
New Cutoff Scores for Delirium Screening Tools to Predict Patient Mortality Yamanashi, T. Iwata, M. Crutchley, K. J. Sullivan, E. J. Malicoat, J. R. Anderson, Z. M. Marra, P. S. Chang, G. Kaneko, K. Shinozaki, E. Lee, S. Shinozaki, G. J Am Geriatr Soc 2021

Cam-icu
Doss
Drs-r-98
delirium
mortality

Intraoperative dexmedetomidine for prevention of postoperative delirium in elderly patients with mild cognitive impairment Xin, X. Chen, J. Hua, W. Wang, H. Int J Geriatr Psychiatry 2021

Aged
Anesthesia, General
Cognitive Dysfunction/etiology/prevention & control
Delirium/prevention & control
Dexmedetomidine/therapeutic use
Humans
Postoperative Complications/prevention & control
blood‐brain barrier
dexmedetomidine
elderly
mild cognitive impairment
neuroinflammation
postoperative delirium

The risk factors for postoperative delirium in adult patients after hip fracture surgery: a systematic review and meta-analysis Wu, J. Yin, Y. Jin, M. Li, B. Int J Geriatr Psychiatry 2021

Blood Transfusion
Delirium/epidemiology/etiology
Hip Fractures/surgery
Humans
Incidence
Postoperative Complications/epidemiology
Risk Factors
adult patients
hip fracture surgery
postoperative delirium

Preoperative Delirium Nursing Model Initiatives to Determine the Incidence of Postoperative Delirium Among Elderly Orthopaedic Patients Wu, H. Kapur, A. Gibson, B. Bubb, K. Alrawashdeh, M. Cipkala-Gaffin, J. Orthop Nurs 2021
Challenges of Delirium Management in Patients with Traumatic Brain Injury: From Pathophysiology to Clinical Practice Williams Roberson, S. Patel, M. B. Dabrowski, W. Ely, E. W. Pakulski, C. Kotfis, K. Curr Neuropharmacol 2021

barbiturates
critical care
delirium
dexmedetomidine
electroencephalography
post-traumatic delirium
traumatic brain injury
xanthohumol

A Systematic Review of Delirium Biomarkers and Their Alignment with the NIA-AA Research Framework Wang, S. Lindroth, H. Chan, C. Greene, R. Serrano-Andrews, P. Khan, S. Rios, G. Jabbari, S. Lim, J. Saykin, A. J. Khan, B. J Am Geriatr Soc 2021

Alzheimerʼs disease
biomarkers
delirium
inflammation
mild cognitive impairment
neuroimaging
preclinical Alzheimerʼʼs disease

Development and validation of the Terminal Delirium-Related Distress Scale to assess irreversible terminal delirium Uchida, M. Akechi, T. Morita, T. Shima, Y. Igarashi, N. Miyashita, M. Palliat Support Care 2021

Cancer
Delirium
End of life
Palliative care
Terminal delirium

Targeted metabolomics analysis of postoperative delirium Tripp, B. A. Dillon, S. T. Yuan, M. Asara, J. M. Vasunilashorn, S. M. Fong, T. G. Metzger, E. D. Inouye, S. K. Xie, Z. Ngo, L. H. Marcantonio, E. R. Libermann, T. A. Otu, H. H. Sci Rep 2021
Hospitalized older adult: predictors of functional decline Tavares, J. P. A. Nunes, Lanv Grácio, J. C. G. Rev Lat Am Enfermagem 2021

Activities of Daily Living
Aged
Aged, 80 and over
Delirium
Female
Hospitalization
Humans
Male
Patient Discharge
Prospective Studies
Risk Factors

Postoperative delirium in patients undergoing tumor resection with reconstructive surgery for oral cancer Takahashi, N. Hiraki, A. Kawahara, K. Nagata, M. Yoshida, R. Matsuoka, Y. Tanaka, T. Obayashi, Y. Sakata, J. Nakashima, H. Arita, H. Shinohara, M. Nakayama, H. Mol Clin Oncol 2021

early postoperative ambulation
oral cancer
postoperative delirium
reconstructive surgery
tumor resection

Prevalence of ICU Delirium in Postoperative Pediatric Cardiac Surgery Patients Staveski, S. L. Pickler, R. H. Khoury, P. R. Ollberding, N. J. Donnellan, A. L. Mauney, J. A. Lincoln, P. A. Baird, J. D. Gilliland, F. L. Merritt, A. D. Presnell, L. B. Lanese, A. R. Lisanti, A. J. Large, B. J. Fineman, L. D. Gibson, K. H. Mohler, L. A. Pediatr Crit Care Med 2021

Adolescent
Cardiac Surgical Procedures/adverse effects
Child
Delirium/diagnosis/epidemiology/etiology
Humans
Intensive Care Units, Pediatric
North America/epidemiology
Prevalence
Prospective Studies
Risk Factors

Physostigmine for prevention of postoperative delirium and long-term cognitive dysfunction in liver surgery: A double-blinded randomised controlled trial Spies, C. D. Knaak, C. Mertens, M. Brockhaus, W. R. Shadenok, A. Wiebach, J. Kunzmann, K. Feldheiser, A. Pratschke, J. Müller, O. Kipping, V. Fabian, M. Abels, W. Borchers, F. Akyüz, L. Ely, E. W. Wernecke, K. D. Menon, D. K. Piper, S. K. Eur J Anaesthesiol 2021
Intraoperative clonidine to prevent postoperative emergence delirium following sevoflurane anesthesia in pediatric patients: a randomized clinical trial Sousa-Júnior, F. A. Souza, A. S. R. Lima, L. C. Santos Í, G. M. Menezes, L. A. P. Ratis, Papl Couceiro, T. C. M. Braz J Anesthesiol 2021

Anesthesia
Children
Clonidine
Emergence delirium
Psychomotor agitation
Tonsillectomy

Training hospital inpatient nursing to know (THINK) delirium: A nursing educational program Solberg, L. M. Campbell, C. S. Jones, K. Vaughn, I. Suryadevara, U. Fernandez, C. Shorr, R. Geriatr Nurs 2021

Delirium
Dementia
Non-pharmacologic interventions
Nursing education

Delirium is associated with an increased morbidity and in-hospital mortality in cancer patients: Results from a prospective cohort study Seiler, A. Blum, D. Deuel, J. W. Hertler, C. Schettle, M. Zipser, C. M. Ernst, J. Schubert, M. von Känel, R. Boettger, S. Palliat Support Care 2021

Cancer patients
Delirium
Morbidity
Mortality
Precipitating factors
Predisposing factors

Delirium Triage Screen/Brief Confusion Assessment Method in Adult Orthopaedic and Hematological Patients: A Validation Study Sederstrom, J. R. Aliory, C. D. Hanneman, E. M. Buras, M. R. Orthop Nurs 2021
"SQiD, the Single Question in Delirium; can a single question help clinicians to detect delirium in hospitalised cancer patients?" running heading Single Question in Delirium" (Bcan-D-20-01665) Sands, M. B. Sharma, S. Carpenter, L. Hartshorn, A. Lee, J. T. Lujic, S. Congdon, M. E. Buchanan, A. M. Agar, M. Vardy, J. L. BMC Cancer 2021

Cancer
Delirium
Detection
Hospital
Oncology
Screening

Factors Impacting Early Mobilization Following Hip Fracture: An Observational Study Said, C. M. Delahunt, M. Ciavarella, V. Al Maliki, D. Boys, A. M. Vogrin, S. Berney, S. J Geriatr Phys Ther 2021
Risk factors of postoperative delirium in the knee and hip replacement patients: a systematic review and meta-analysis Rong, X. Ding, Z. C. Yu, H. D. Yao, S. Y. Zhou, Z. K. J Orthop Surg Res 2021

Hip replacement
Knee replacement
Postoperative delirium
Risk factors

Characteristics of Younger and Older Adults with Hospital-Acquired Delirium: a Claims Data Study Spanning 14 years Rohatgi, N. Weng, Y. Ahuja, N. Lansberg, M. G. J Gen Intern Med 2021

Aged
Delirium/diagnosis/epidemiology
Geriatric Assessment
Hospitals
Humans

Factors Associated with Hospital-Acquired Delirium in Patients 18-65 Years Old Rohatgi, N. Weng, Y. Ahuja, N. Lansberg, M. G. J Gen Intern Med 2021

Adolescent
Adult
Aged
Delirium/diagnosis/epidemiology
Hospitalization
Hospitals
Humans
Middle Aged
Risk Factors
Young Adult

Implementation of a multicomponent intervention sign to reduce delirium in orthopaedic inpatients (MIND-ORIENT): a quality improvement project Reppas-Rindlisbacher, C. Siddhpuria, S. Wong, E. K. Lee, J. Y. Gabor, C. Curkovic, A. Khalili, Y. Mavrak, C. De Freitas, S. Eshak, K. Patterson, C. BMJ Open Qual 2021

evidence-based practice
geriatrics
healthcare quality improvement
hip fractures
nurses

Anticholinergic Burden Does Not Influence Delirium Subtype or the Delirium-Mortality Association in Hospitalized Older Adults: Results from a Prospective Cohort Study Rawle, M. J. McCue, L. Sampson, E. L. Davis, D. Vickerstaff, V. Drugs Aging 2021
Incidence and Risk Factors of Delirium in the Intensive Care Unit: A Prospective Cohort Rahimi-Bashar, F. Abolhasani, G. Manouchehrian, N. Jiryaee, N. Vahedian-Azimi, A. Sahebkar, A. Biomed Res Int 2021

Adult
Analgesics/administration & dosage
Anti-Bacterial Agents/administration & dosage
Delirium/diagnosis/ epidemiology/mortality
Female
Humans
Hypnotics and Sedatives/administration & dosage
Incidence
Intensive Care Units
Male
Middle Aged
Prospective Studies
Risk Factors
Severity of Illness Index

Implementing Delirium Prevention in the Era of COVID-19 Radhakrishnan, N. S. Mufti, M. Ortiz, D. Maye, S. T. Melara, J. Lim, D. Rosenberg, E. I. Price, C. C. J Alzheimers Dis 2021

Aged
Alzheimer Disease/ diagnosis/psychology/ therapy
COVID-19/epidemiology/ prevention & control/psychology
Delirium/epidemiology/ prevention & control/psychology
Humans
Male
Alzheimer’s disease
Covid-19
dementia
hospitalization
quality of health care
tertiary care centers

Prevalence and risk factors of delirium in psychogeriatric outpatients Quispel-Aggenbach, D. W. P. Schep-de Ruiter, E. P. R. van Bergen, W. Bolling, J. R. Zuidema, S. U. Luijendijk, H. J. Int J Geriatr Psychiatry 2021

Aged
Delirium/epidemiology/etiology
Geriatric Psychiatry
Humans
Outpatients
Prevalence
Risk Factors
delirium
elderly
older patient

Prevalence and risk factors for delirium in critically ill patients with COVID-19 (COVID-D): a multicentre cohort study Pun, B. T. Badenes, R. Heras La Calle, G. Orun, O. M. Chen, W. Raman, R. Simpson, B. K. Wilson-Linville, S. Hinojal Olmedillo, B. Vallejo de la Cueva, A. van der Jagt, M. Navarro Casado, R. Leal Sanz, P. Orhun, G. Ferrer Gómez, C. Núñez Vázquez, K. Pi Lancet Respir Med 2021

Aged
COVID-19/ psychology
Coma/ epidemiology/virology
Critical Illness/psychology
Delirium/ epidemiology/virology
Female
Humans
Hypnotics and Sedatives/therapeutic use
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Prevalence
Respiration, Artificial/psychology/statistics & numerical data
Retrospective Studies
Risk Factors
SARS-CoV-2

Risk prediction models for emergence delirium in paediatric general anaesthesia: a systematic review Petre, M. A. Saha, B. Kasuya, S. Englesakis, M. Gai, N. Peliowski, A. Aoyama, K. BMJ Open 2021

Anesthesia, General/ adverse effects
Bias
Child
Cognition/ drug effects
Cognition Disorders/chemically induced
Emergence Delirium/ chemically induced/diagnosis
Humans
Risk Assessment
Surgical Procedures, Operative
Delirium & cognitive disorders
Paediatric anaesthesia
emergence delirium

The Effects of Propofol or Dexmedetomidine Sedation on Postoperative Recovery in Elderly Patients Receiving Lower Limb Surgery under Spinal Anesthesia: A Retrospective Propensity Score-Matched Analysis Park, J. W. Kim, E. K. Lee, H. T. Park, S. Do, S. H. J Clin Med 2021

dexmedetomidine
intraoperative sedation
postoperative delirium
propofol

High proportion of thiamine deficiency in referred cancer patients with delirium: a retrospective descriptive study Onishi, H. Sato, I. Uchida, N. Takahashi, T. Furuya, D. Ebihara, Y. Yoshioka, A. Ito, H. Ishida, M. Eur J Clin Nutr 2021
Association between discontinuation of benzodiazepine receptor agonists and post-operative delirium among inpatients with liaison intervention: A retrospective cohort study Omichi, C. Ayani, N. Oya, N. Matsumoto, Y. Tanaka, M. Morimoto, T. Kadotani, H. Narumoto, J. Compr Psychiatry 2021

Benzodiazepines/adverse effects
Delirium/chemically induced/diagnosis/epidemiology
Humans
Inpatients
Receptors, GABA-A
Retrospective Studies
benzodiazepine receptor agonist
benzodiazepine withdrawal syndrome
consultation-liaison psychiatry
discontinuation
post-operative delirium

The Independent Association of Prestroke Psychiatric Symptoms and Acute Phase Delirium with Poststroke Mortality at One Year in Nigeria Ojagbemi, A. Bello, T. Owolabi, M. Baiyewu, O. J Stroke Cerebrovasc Dis 2021

Delirium/diagnosis/ mortality/psychology
Female
Humans
Longitudinal Studies
Male
Mental Disorders/diagnosis/ mortality/psychology
Mental Health
Middle Aged
Nigeria/epidemiology
Prognosis
Prospective Studies
Risk Assessment
Risk Factors
Stroke/diagnosis/ mortality/psychology
Surveys and Questionnaires
Time Factors
Mental health complications
Neurocognitive disorders
Prestroke symptoms
Stroke burden
Sub-Saharan Africa

Depression predicts long-term cognitive impairment in survivors of critical illness Nordness, M. F. Bipin Patel, M. Erickson, C. R. Kiehl, A. Jackson, J. C. Raman, R. Pandharipande, P. P. Ely, E. W. Wilson, J. E. J Trauma Acute Care Surg 2021

Aged
Cognitive Dysfunction/ etiology
Critical Illness/ psychology
Depression/ complications/etiology
Female
Humans
Intensive Care Units/statistics & numerical data
Male
Middle Aged
Neuropsychological Tests
Prospective Studies
Stress Disorders, Post-Traumatic/complications/etiology
Survivors/ psychology/statistics & numerical data

Effects of uncomfortable care and histamine H2-antagonists on delirium in acute stroke: A propensity score analysis Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. J Neurol Sci 2021

Delirium/epidemiology/etiology
Histamine
Histamine H2 Antagonists
Humans
Intensive Care Units
Propensity Score
Prospective Studies
Stroke/complications/drug therapy
Adverse effect
Anti-ulcer agent
Clinical nursing research
Gastrointestinal haemorrhage
Immobilization
Indwelling catheter
Prevention and control
Sleep deprivation

Family automated voice reorientation (FAVoR) intervention for mechanically ventilated patients in the intensive care unit: Study protocol for a randomized controlled trial Munro, C. L. Liang, Z. Ji, M. Elías, M. N. Chen, X. Calero, K. Ely, E. W. Contemp Clin Trials 2021

Cognition
Critical illness
Delirium
Mechanical ventilation
Randomized controlled trial
Sleep

Evaluation of a delirium awareness podcast for undergraduate nursing students in Northern Ireland: a pre-/post-test study Mitchell, G. Scott, J. Carter, G. Wilson, C. B. BMC Nurs 2021

Constructivist pedagogy
Delirium
Nurse education
Nursing student
Pedagogical research
Podcast
Quantitative research methods

Impact of delirium in acute cardiac care unit after transcatheter aortic valve replacement Luque, T. Noriega, F. J. McInerney, A. Travieso, A. Corrochano, D. Tirado-Conte, G. Ferrera, C. Fossati, S. Jimenez-Quevedo, P. Nuñez-Gil, I. Gonzalo, N. Escaned, J. Macaya, C. Fernández-Ortiz, A. Nombela-Franco, L. Viana-Tejedor, A. Int J Cardiol 2021

Aortic Valve/surgery
Aortic Valve Stenosis/surgery
Delirium/diagnosis/epidemiology/etiology
Humans
Length of Stay
Postoperative Complications/diagnosis/epidemiology
Risk Factors
Transcatheter Aortic Valve Replacement/adverse effects
Treatment Outcome
Acute cardiac care
Aortic stenosis
Delirium
Transcatheter aortic valve replacement

Preoperative Prognostic Nutritional Index Value is Related to Postoperative Delirium in Elderly Patients After Noncardiac Surgery: A Retrospective Cohort Study Liu, H. Dai, M. Guan, H. Gao, X. Zhou, Y. Sun, X. Zhou, J. Hu, X. Li, X. Song, Y. Han, Y. Cao, J. Risk Manag Healthc Policy 2021

elderly patients
noncardiac surgery
nutritional status
postoperative delirium
prognostic nutritional index

Implementation of ABCDEF care bundle in intensive care units: A cross-sectional survey Liang, S. Chau, J. P. C. Lo, S. H. S. Li, S. Gao, M. Nurs Crit Care 2021

ABCDEF care bundle
delirium
intensive care unit
registered nurses

Lymphocyte and NK Cell Counts Can Predict Sepsis-Associated Delirium in Elderly Patients Li, D. Zhang, J. Bai, G. Chen, J. Cheng, W. Cui, N. Front Aging Neurosci 2021

NK cell
delirium
elderly people
lymphocyte subsets
sepsis-associated delirium

Safety and Efficacy of Dexmedetomidine in Acutely Ill Adults Requiring Noninvasive Ventilation: A Systematic Review and Meta-analysis of Randomized Trials Lewis, K. Piticaru, J. Chaudhuri, D. Basmaji, J. Fan, E. Møller, M. H. Devlin, J. W. Alhazzani, W. Chest 2021

dexmedetomidine
noninvasive ventilation
positive pressure ventilation
respiratory failure
sedation

Pharmacological strategies to prevent postoperative delirium: a systematic review and network meta-analysis Lee, J. M. Cho, Y. J. Ahn, E. J. Choi, G. J. Kang, H. Anesth Pain Med (Seoul) 2021

Delirium
Network meta-analysis
Pharmacology
Surgical procedures

Evaluation of Melatonin Practices for Delirium in Pediatric Critically Ill Patients Laudone, T. W. Beck, S. D. Lahr, H. J. J Pediatr Pharmacol Ther 2021

antipsychotic
delirium
melatonin
pediatric intensive care unit
prophylaxis
sedation

Results from a double blinded, randomised, placebo-controlled, feasibility trial of melatonin for the treatment of delirium in older medical inpatients Lange, P. W. Clayton-Chubb, D. I. Watson, R. Maier, A. B. Intern Med J 2021

Aged
Delirium/diagnosis/drug therapy
Double-Blind Method
Feasibility Studies
Humans
Inpatients
Melatonin
delirium
neurocognitive disorder
sepsis-associated encephalopathy
sleep
treatment

Delirium, Cerebral Perfusion, and High-Frequency Vital-Sign Monitoring in the Critically Ill. The CONFOCAL-2 Feasibility Study Khan, J. M. Wood, M. D. Lee, K. F. H. Maslove, D. Muscedere, J. English, S. W. Ball, I. Slessarev, M. Boyd, J. G. Ann Am Thorac Soc 2021

cerebral oxygenation
cognitive outcomes
critical illness
delirium
near-infrared spectroscopy

Preoperative brain MRI features and occurrence of postoperative delirium Kant, I. M. J. de Bresser, J. van Montfort, S. J. T. Mutsaerts, Hjmm Witkamp, T. D. Buijsrogge, M. Spies, C. Hendrikse, J. Slooter, A. J. C. J Psychosom Res 2021

Aged
Brain/ diagnostic imaging
Delirium/ etiology/pathology
Female
Humans
Magnetic Resonance Imaging/ adverse effects
Male
Preoperative Period
Prospective Studies
Cortical infarcts
Delirium
MRI markers
White matter hyperintensities

Intraoperative monitoring parameters and postoperative delirium: Results of a prospective cross-sectional trial Jung, C. Hinken, L. Fischer-Kumbruch, M. Trübenbach, D. Fielbrand, R. Schenk, I. Diegmann, O. Krauß, T. Scheinichen, D. Schultz, B. Medicine (Baltimore) 2021

Adult
Aged
Aged, 80 and over
Anesthetics, Inhalation/adverse effects/therapeutic use
Cross-Sectional Studies
Delirium/ classification/ etiology
Female
Humans
Logistic Models
Male
Middle Aged
Monitoring, Intraoperative/ methods/statistics & numerical data
Postoperative Complications/classification/physiopathology
Prospective Studies
Sevoflurane/adverse effects/therapeutic use
Sufentanil/adverse effects/therapeutic use

Development of the AL-O-A Score for Delirium Screening in Acute Internal Medicine: a Monocentric Prospective Study John, G. Bovet, V. Verdon, V. Zender, H. Donzé, J. J Gen Intern Med 2021

adult
delirium
inpatients
internal medicine
prospective study
score

Intravenous Iron in a Prehabilitation Program for Older Surgical Patients: Prospective Cohort Study Janssen, T. L. Steyerberg, E. W. van Gammeren, A. J. Ho, G. H. Gobardhan, P. D. van der Laan, L. J Surg Res 2021

Abdomen/surgery
Aged
Aged, 80 and over
Anemia/epidemiology
Anemia, Iron-Deficiency/drug therapy/epidemiology
Blood Transfusion/statistics & numerical data
Cohort Studies
Delirium/epidemiology
Elective Surgical Procedures
Female
Hemoglobins/analysis
Humans
Infusions, Intravenous
Iron/ administration & dosage
Male
Postoperative Complications/epidemiology/prevention & control
Preoperative Care/ methods
Prospective Studies
(Iron deficiency) anemia
Colorectal surgery
Delirium
Vascular surgery

Comparative associations between anticholinergic burden and emergency department visits for anticholinergic adverse events in older Korean adults: a nested case-control study using national claims data for validation of a novel country-specific scale Hwang, S. Chung, J. E. Jun, K. Ah, Y. M. Kim, K. I. Lee, J. Y. BMC Pharmacol Toxicol 2021

Anticholinergic syndromes
Cholinergic antagonists
Emergency medical services
Geriatrics

Evaluation of QTc Interval Effects of Antipsychotic Medications for Intensive Care Unit Delirium in Pediatric Patients Hutchins, L. M. Shipman, A. Zimmerman, K. O. Heath, T. S. J Pediatr Pharmacol Ther 2021

QTc interval prolongation
antipsychotics
intensive care unit delirium
pediatric delirium

Implementing a Rapid, Two-Step Delirium Screening Protocol in Acute Care: Barriers and Facilitators Husser, E. K. Fick, D. M. Boltz, M. Shrestha, P. Siuta, J. Malloy, S. Overstreet, A. Leslie, D. L. Ngo, L. Jung, Y. Inouye, S. K. Marcantonio, E. R. J Am Geriatr Soc 2021

delirium
hospitalized older adults
observations

Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J. J Clin Anesth 2021

Elderly patients
General anaesthesia
Mean arterial pressure
Postoperative delirium

Personalized Blood Pressure Management During Cardiac Surgery With Cerebral Autoregulation Monitoring: A Randomized Trial Hogue, C. W. Brown, C. H. th Hori, D. Ono, M. Nomura, Y. Balmert, L. C. Srdanovic, N. Grafman, J. Brady, K. Semin Thorac Cardiovasc Surg 2021

Blood pressure
Cardiopulmonary bypass
Cerebral autoregulation
Neurological complications

Clinical Features and Outcomes of Patients with Dementia Compared to an Aging Cohort Hospitalized During the Initial New York City COVID-19 Wave Harb, A. A. Chen, R. Chase, H. S. Natarajan, K. Noble, J. M. J Alzheimers Dis 2021

Aged
Aged, 80 and over
COVID-19/ epidemiology/mortality
Comorbidity
Delirium/ epidemiology/mortality
Dementia/ epidemiology/mortality
Female
Hospital Mortality
Hospitalization
Humans
Male
New York City/epidemiology
Pandemics
Retrospective Studies
Advance directives
Covid-19
delirium
dementia
geriatrics
neurology