What is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!
How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.
Reference Information
- Title
- Pharmacologic Management of Intensive Care Unit Delirium: Clinical Prescribing Practices and Outcomes in More Than 8500 Patient Encounters
- Authors
- Boncyk, C. S. Farrin, E. Stollings, J. L. Rumbaugh, K. Wilson, J. E. Marshall, M. Feng, X. Shotwell, M. S. Pandharipande, P. P. Hughes, C. G.
- Year
- 2021
- Journal
- Anesth Analg
- Abstract
BACKGROUND: Pharmacologic agents are frequently utilized for management of intensive care unit (ICU) delirium, yet prescribing patterns and impact of medication choices on patient outcomes are poorly described. We sought to describe prescribing practices for management of ICU delirium and investigate the independent association of medication choice on key in-hospital outcomes including delirium resolution, in-hospital mortality, and days alive and free of the ICU or hospital. METHODS: A retrospective study of delirious adult ICU patients at a tertiary academic medical center. Data were obtained regarding daily mental status (normal, delirious, and comatose), pharmacologic treatment, hospital course, and survival via electronic health record. Daily transition models were constructed to assess the independent association of previous day mental status and medication administration on mental status the following day and in-hospital mortality, after adjusting for prespecified covariates. Linear regression models investigated the association of medication administration on days alive and free of the ICU or the hospital during the first 30 days after ICU admission. RESULTS: We identified 8591 encounters of ICU delirium. Half (45.6%) of patients received pharmacologic treatment for delirium, including 45.4% receiving antipsychotics, 2.2% guanfacine, and 0.84% valproic acid. Median highest Richmond Agitation-Sedation Scale (RASS) score was 1 (0, 1) in patients initiated on medications and 0 (-1, 0) for nonrecipients. Haloperidol, olanzapine, and quetiapine comprised >97% of antipsychotics utilized with 48% receiving 2 or more and 20.6% continued on antipsychotic medications at hospital discharge. Haloperidol and olanzapine were associated with greater odds of continued delirium (odds ratio [OR], 1.48; 95% confidence interval [95% CI], 1.30-1.65; P < .001 and OR, 1.37; 95% CI, 1.20-1.56; P = .003, respectively) and increased hazard of in-hospital mortality (hazard ratio [HR], 1.46; 95% CI, 1.10-1.93; P = .01 and HR, 1.67; 95% CI, 1.14-2.45; P = .01, respectively) while quetiapine showed a decreased hazard of in-hospital mortality (HR, 0.58; 95% CI, 0.40-0.84; P = .01). Haloperidol, olanzapine, and quetiapine were associated with fewer days alive and free of hospitalization (all P < .001). There was no significant association of any antipsychotic medication with days alive and free of the ICU. Neither guanfacine nor valproic acid were associated with in-hospital outcomes examined. CONCLUSIONS: Pharmacologic interventions for management of ICU delirium are common, most often with antipsychotics, and frequently continued at hospital discharge. These medications may not portend benefit, may introduce additional harm, and should be used with caution for delirium management. Continuation of these medications through hospitalization and discharge draws into question their safety and role in patient recovery.
- PMID
- Keywords
- Page(s)
- Volume
- Issue
Title | Authors | Journal | Year | Keywords |
---|---|---|---|---|
Development of the AL-O-A Score for Delirium Screening in Acute Internal Medicine: a Monocentric Prospective Study | John, G. Bovet, V. Verdon, V. Zender, H. Donzé, J. | J Gen Intern Med | 2021 |
adult |
Intravenous Iron in a Prehabilitation Program for Older Surgical Patients: Prospective Cohort Study | Janssen, T. L. Steyerberg, E. W. van Gammeren, A. J. Ho, G. H. Gobardhan, P. D. van der Laan, L. | J Surg Res | 2021 |
Abdomen/surgery |
Comparative associations between anticholinergic burden and emergency department visits for anticholinergic adverse events in older Korean adults: a nested case-control study using national claims data for validation of a novel country-specific scale | Hwang, S. Chung, J. E. Jun, K. Ah, Y. M. Kim, K. I. Lee, J. Y. | BMC Pharmacol Toxicol | 2021 |
Anticholinergic syndromes |
Evaluation of QTc Interval Effects of Antipsychotic Medications for Intensive Care Unit Delirium in Pediatric Patients | Hutchins, L. M. Shipman, A. Zimmerman, K. O. Heath, T. S. | J Pediatr Pharmacol Ther | 2021 |
QTc interval prolongation |
Implementing a Rapid, Two-Step Delirium Screening Protocol in Acute Care: Barriers and Facilitators | Husser, E. K. Fick, D. M. Boltz, M. Shrestha, P. Siuta, J. Malloy, S. Overstreet, A. Leslie, D. L. Ngo, L. Jung, Y. Inouye, S. K. Marcantonio, E. R. | J Am Geriatr Soc | 2021 |
delirium |
Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial | Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J. | J Clin Anesth | 2021 |
Elderly patients |
Personalized Blood Pressure Management During Cardiac Surgery With Cerebral Autoregulation Monitoring: A Randomized Trial | Hogue, C. W. Brown, C. H. th Hori, D. Ono, M. Nomura, Y. Balmert, L. C. Srdanovic, N. Grafman, J. Brady, K. | Semin Thorac Cardiovasc Surg | 2021 |
Blood pressure |
Clinical Features and Outcomes of Patients with Dementia Compared to an Aging Cohort Hospitalized During the Initial New York City COVID-19 Wave | Harb, A. A. Chen, R. Chase, H. S. Natarajan, K. Noble, J. M. | J Alzheimers Dis | 2021 |
Aged |
Perioperative Multidisciplinary Delirium Prevention: A Longitudinal Case Report | Hamlet, K. M. Pasternak, E. Rabai, F. Mufti, M. Hernaiz Alonso, C. Price, C. C. | A A Pract | 2021 | |
Cerebrospinal Fluid Concentration of Neurogranin in Hip Fracture Patients with Delirium | Halaas, N. B. Zetterberg, H. Idland, A. V. Knapskog, A. B. Watne, L. O. Blennow, K. | J Alzheimers Dis | 2021 |
Alzheimer’s disease |
A retrospective study of factors associated with persistent delirium | Goto, H. Yamauchi, T. Okumura, K. Matsuoka, K. Toritsuka, M. Yasuno, F. Uemura, H. Kuki, K. Makinodan, M. Kishimoto, T. | Psychogeriatrics | 2021 |
Case-Control Studies |
Association Between Early Tracheostomy and Delirium in Older Adults in the United States | Gazda, A. J. Kwak, M. J. Jani, P. Dinh, K. Hussain, R. Dronavalli, G. Warner, M. Salas De Armas, I. Kumar, S. Nathan, S. Kar, B. Gregoric, I. D. Patel, B. Akkanti, B. | J Cardiothorac Vasc Anesth | 2021 |
delirium |
Poor outcomes of delirium in the intensive care units are amplified by increasing age: A retrospective cohort study | Gao, W. Zhang, Y. P. Jin, J. F. | World J Emerg Med | 2021 |
Aging |
Postoperative Delirium is Associated With Prolonged Head and Neck Resection and Reconstruction Surgery: An Institutional Study | Edwards, D. A. Medhavy, A. Hoffman, O. G. Hoffman, G. R. | J Oral Maxillofac Surg | 2021 |
Aged |
Delirium Assessment in Critically Ill Older Adults: Considerations During the COVID-19 Pandemic | Duggan, M. C. Van, J. Ely, E. W. | Crit Care Clin | 2021 |
Aged |
Delirium occurrence in older Irish adults admitted to an acute medical hospital: a prospective cohort study | Dolan, C. Mohd Zubir, M. Melvin, V. McCarthy, G. Meagher, D. Adamis, D. | Ir J Psychol Med | 2021 |
Delirium |
Clinical utility of brain computed tomography in prediction of post-stroke delirium | Czyzycki, M. Glen, A. Slowik, A. Chrzan, R. Dziedzic, T. | J Neural Transm (Vienna) | 2021 |
Brain atrophy |
Risk factors for long-term cognitive impairment in ICU survivors: A multicenter, prospective cohort study | Collet, M. O. Egerod, I. Thomsen, T. Wetterslev, J. Lange, T. Ebdrup, B. H. Perner, A. | Acta Anaesthesiol Scand | 2021 | |
Integration of family caregivers in delirium prevention care for hospitalized older adults: A case study analysis | Cohen, C. Pereira, F. Kampel, T. Bélanger, L. | J Adv Nurs | 2021 |
Aged |
Investigating how electroencephalogram measures associate with delirium: A systematic review | Boord, M. S. Moezzi, B. Davis, D. Ross, T. J. Coussens, S. Psaltis, P. J. Bourke, A. Keage, H. A. D. | Clin Neurophysiol | 2021 |
Delirium |
Pharmacologic Management of Intensive Care Unit Delirium: Clinical Prescribing Practices and Outcomes in More Than 8500 Patient Encounters | Boncyk, C. S. Farrin, E. Stollings, J. L. Rumbaugh, K. Wilson, J. E. Marshall, M. Feng, X. Shotwell, M. S. Pandharipande, P. P. Hughes, C. G. | Anesth Analg | 2021 | |
Predictors of delirium in older patients at the emergency department: a prospective multicentre derivation study | Béland, E. Nadeau, A. Carmichael, P. H. Boucher, V. Voyer, P. Pelletier, M. Gouin, É Daoust, R. Berthelot, S. Lamontagne, M. E. Morin, M. Lemire, S. Vu, T. T. M. Émond, M. | CJEM | 2021 |
Delirium |
Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort | Atkins, J. L. Pilling, L. C. Heales, C. J. Savage, S. Kuo, C. L. Kuchel, G. A. Steffens, D. C. Melzer, D. | J Alzheimers Dis | 2021 |
Cohort |
Awareness of Delirium by ICU Nurses | Asmar, I. T. Yaseen, K. S. Jaghama, M. K. Khawaja, Y. F. Alwredat, A. A. Sadaqa, M. H. | Crit Care Nurs Q | 2021 | |
Psychiatric Clinical Profiles and Pharmacological Interactions in COVID-19 Inpatients Referred to a Consultation Liaison Psychiatry Unit: a Cross-Sectional Study | Arbelo, N. López-Pelayo, H. Sagué, M. Madero, S. Pinzón-Espinosa, J. Gomes-da-Costa, S. Ilzarbe, L. Anmella, G. Llach, C. D. Imaz, M. L. Cámara, M. M. Pintor, L. | Psychiatr Q | 2021 |
Covid-19 |
Octogenarian patients' sleep and delirium experiences in hospital and four years after aortic valve replacement: a qualitative interview study | Amofah, H. A. Broström, A. Instenes, I. Fridlund, B. Haaverstad, R. Kuiper, K. Ranhoff, A. H. Norekvål, T. M. | BMJ Open | 2021 |
Aged, 80 and over |
Delirium and quality of life in critically ill patients: a prospective cohort study | Luz, L. F. D. S. Santos, M. C. D. Ramos, T. A. Almeida, C. B. Rover, M. C. Dal'Pizzol, C. P. Pohren, C. L. D. S. Martins, A. V. D. S. Boniatti, M. M. | Rev Bras Ter Intensiva | 2020 |
adult |
Bispectral Index Monitoring With Density Spectral Array for Delirium Detection | Luo, A. Muraida, S. Pinchotti, D. Richardson, E. Ye, E. Hollingsworth, B. Win, A. Myers, O. Langsjoen, J. Valles, E. Zolyomi, A. Quinn, D. K. | Psychosomatics | 2020 |
bispectral index monitoring |
Delirium prediction in the intensive care unit: a temporal approach | Lucini, F. R. Fiest, K. M. Stelfox, H. T. Lee, J. | Annu Int Conf IEEE Eng Med Biol Soc | 2020 |
Alberta |
Impact of place of residence, frailty and other factors on rehabilitation outcomes post hip fracture | Low, S. Wee, E. Dorevitch, M. | Age Ageing | 2020 |
clinical frailty scale |
Ramelteon for Decreasing Delirium in Surgical Intensive Care Unit Patients | Lopez, C. N. Fuentes, A. Dhala, A. Balk, J. | Clinical Medicine Insights: Psychiatry | 2020 |
haloperidol |
Different depths of sedation versus risk of delirium in adult mechanically ventilated patients: A systematic review and meta-analysis | Long, L. Ren, S. Gong, Y. Zhao, H. He, C. Shen, L. Zhao, H. Ma, P. | PLoS One | 2020 |
Adult |
Association of Troponin Levels With Mortality in Italian Patients Hospitalized With Coronavirus Disease 2019: Results of a Multicenter Study | Lombardi, C. M. Carubelli, V. Iorio, A. Inciardi, R. M. Bellasi, A. Canale, C. Camporotondo, R. Catagnano, F. Dalla Vecchia, L. A. Giovinazzo, S. Maccagni, G. Mapelli, M. Margonato, D. Monzo, L. Nuzzi, V. Oriecuia, C. Peveri, G. Pozzi, A. Provenzale, G. S | JAMA Cardiol | 2020 |
Aged |
Role of dexmedetomidine in the treatment of delirium in critically ill patients: a systematic review and meta-analysis | Liu, X. Xiong, J. Tang, Y. Gong, C. C. Wang, D. F. | Minerva anestesiologica | 2020 |
adult |
Delirium Severity Trajectories and Outcomes in ICU Patients. Defining a Dynamic Symptom Phenotype | Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. | Ann Am Thorac Soc | 2020 |
critical care |
Risk factors for postoperative delirium in patients with triple-branched stent graft implantation | Lin, Y. Chen, Q. Zhang, H. Chen, L. W. Peng, Y. Huang, X. Chen, Y. Li, S. Lin, L. | J Cardiothorac Surg | 2020 |
Apache |
Cerebrospinal fluid cholinergic biomarkers are associated with postoperative delirium in elderly patients undergoing Total hip/knee replacement: a prospective cohort study | Lin, X. Tang, J. Liu, C. Li, X. Cao, X. Wang, B. Dong, R. Xu, W. Yu, X. Wang, M. Bi, Y. | BMC Anesthesiol | 2020 |
Cerebrospinal fluid |
Effect of Dexmedetomidine on Delirium in Elderly Surgical Patients: A Meta-analysis of Randomized Controlled Trials | Lin, C. Tu, H. Jie, Z. Zhou, X. Li, C. | Ann Pharmacother | 2020 |
delirium |
The relationship between intraoperative cerebral oximetry and postoperative delirium in patients undergoing off-pump coronary artery bypass graft surgery: a retrospective study | Lim, L. Nam, K. Lee, S. Cho, Y. J. Yeom, C. W. Jung, S. Moon, J. Y. Jeon, Y. | BMC Anesthesiol | 2020 |
Cerebral oximetry |
Effects of nonpharmacological delirium-prevention interventions on critically ill patients' clinical, psychological, and family outcomes: A systematic review and meta-analysis | Liang, S. Chau, J. P. C. Lo, S. H. S. Zhao, J. Choi, K. C. | Aust Crit Care | 2020 |
Delirium |
Validation of PREdiction of DELIRium in ICu patients (PRE-DELIRIC) among patients in intensive care units: A retrospective cohort study | Liang, S. Chau, J. P. C. Lo, S. H. S. Bai, L. Yao, L. Choi, K. C. | Nurs Crit Care | 2020 |
Icu |
Prognostic Impact of Delirium in Older People With/Without Dementia: A Retrospective Cohort Study in Taiwan | Liang, C. K. Chuang, H. Y. Hsiao, F. Y. Chou, M. Y. Liu, T. Y. Yang, C. C. Chen, L. K. | Journal of Nutrition, Health and Aging | 2020 |
aged |
Effects of modified version of the Hospital Elder Life Program on post-discharge cognitive function and activities of daily living among older adults undergoing total knee arthroplasty | Liang, C. K. Chu, C. S. Hsu, Y. H. Chou, M. Y. Wang, Y. C. Lin, Y. T. Renn, J. H. Liu, T. Y. Yang, C. C. | Arch Gerontol Geriatr | 2020 |
Cognitive decline |
Incidence and Risk Factors for Delirium in Older Patients Following Intensive Care Unit Admission: A Prospective Observational Study | Li, X. Zhang, L. Gong, F. Ai, Y. | The journal of nursing research : JNR | 2020 |
aged |
Surviving and Thriving 1 Year After Cardiac Surgery: Frailty and Delirium Matter | Li, H. C. Wei, Y. C. Hsu, R. B. Chi, N. H. Wang, S. S. Chen, Y. S. Chen, S. Y. Chen, C. C. H. Inouye, S. K. | Annals of Thoracic Surgery | 2020 |
ADL disability |
Pharmacist Identification of Medication Therapy Problems Involving Cognition Among Older Adults Followed by a Home-Based Care Team | Levine, A. M. P. Emonds, E. E. Smith, M. A. Rickles, N. M. Kuchel, G. A. Steffens, D. C. Ohlheiser, A. Fortinsky, R. H. | Drugs and Aging | 2020 |
aged |
Multicomponent Interventions for the Prevention of Delirium in Hospitalized Older People: A Meta-Analysis | León-Salas, B. Trujillo-Martín, M. M. Martínez Del Castillo, L. P. García-García, J. Pérez-Ros, P. Rivas-Ruiz, F. Serrano-Aguilar, P. | J Am Geriatr Soc | 2020 |
delirium |
Pharmacologic interventions for prevention of delirium in hospitalized older people: A meta-analysis | León-Salas, B. Trujillo-Martín, M. M. Del Castillo, L. P. M. García, J. G. Pérez-Ros, P. Ruiz, F. R. Serrano-Aguilar, P. | Arch Gerontol Geriatr | 2020 |
Aged |
"You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting | Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. | J Clin Nurs | 2020 |
Aged |
The Effect of Intraoperative Magnesium Sulphate Infusion on Emergence Agitation after Ambulatory Ophthalmic Surgery in Children | Lee, Y. J. Kim, B. Y. Park, J. H. Kim, S. Y. Park, H. Y. Do, S. H. | J Clin Med | 2020 |
ambulatory surgery |
Effects of the ABCDE bundle on the prevention of post-intensive care syndrome: A retrospective study | Lee, Y. Kim, K. Lim, C. Kim, J. S. | Journal of advanced nursing | 2020 |
adult |
Effect of Antipsychotics and Non-Pharmacotherapy for the Management of Delirium in People Receiving Palliative Care | Lee, K. Y. Tan, E. C. K. Hanrahan, J. R. Chircop, C. Michael, F. Ong, J. A. | J Pain Palliat Care Pharmacother | 2020 |
Delirium |
Effect of magnesium supplementation on emergence delirium and postoperative pain in children undergoing strabismus surgery: a prospective randomised controlled study | Lee, J. H. Choi, S. Lee, M. Jang, Y. E. Kim, E. H. Kim, J. T. Kim, H. S. | BMC Anesthesiol | 2020 |
Emergence delirium |
Neurologic Complications in Patients With Cancer | Lee, E. Q. | Continuum (Minneapolis, Minn.) | 2020 |
adult |
Melatonin to prevent delirium in patients with advanced cancer: a double blind, parallel, randomized, controlled, feasibility trial | Lawlor, P. G. McNamara-Kilian, M. T. MacDonald, A. R. Momoli, F. Tierney, S. Lacaze-Masmonteil, N. Dasgupta, M. Agar, M. Pereira, J. L. Currow, D. C. Bush, S. H. | BMC Palliat Care | 2020 |
Advanced cancer |
Cognitive function and health-related quality of life 1 year after acute brain injury: An observational study | Larsen, L. K. Møller, K. Petersen, M. Egerod, I. | Acta Anaesthesiol Scand | 2020 |
Acute brain injury |
The One-Two Punch of Delirium and Dementia During the COVID-19 Pandemic and Beyond | LaHue, S. C. Douglas, V. C. Miller, B. L. | Front Neurol | 2020 |
Alzheimer’s disease and related dementias (ADRD) |
Postoperative Delirium is a Risk Factor of Poor Evolution Three Years After Cardiac Surgery: An Observational Cohort Study | Labaste, F. Porterie, J. Bousquet, P. Marcheix, B. Sanchez-Verlaan, P. Frances, B. Valet, P. Dray, C. Minville, V. | Clin Interv Aging | 2020 |
cardiac surgery |
Delirium among Hospitalized Older Adults with Acute Heart Failure Exacerbation | Kwak, M. J. Avritscher, E. Holmes, H. M. Jantea, R. Flores, R. Rianon, N. Chung, T. H. Balan, P. Dhoble, A. | J Card Fail | 2020 |
Acute Heart Failure |
Association between polypharmacy and the persistence of delirium: a retrospective cohort study | Kurisu, K. Miyabe, D. Furukawa, Y. Shibayama, O. Yoshiuchi, K. | Biopsychosoc Med | 2020 |
Classification and regression tree |
Elevated Procalcitonin as a Risk Factor for Postoperative Delirium in the Elderly after Cardiac Surgery-A Prospective Observational Study | Kupiec, A. Adamik, B. Kozera, N. Gozdzik, W. | J Clin Med | 2020 |
cardiac surgery |
The CAM-ICU-7 and ICDSC as measures of delirium severity in critically ill adult patients | Krewulak, K. D. Rosgen, B. K. Ely, E. W. Stelfox, H. T. Fiest, K. M. | PLoS One | 2020 |
Adult |
Adaptation and Validation of a Chart-Based Delirium Detection Tool for the ICU (CHART-DEL-ICU) | Krewulak, K. D. Hiploylee, C. Ely, E. W. Stelfox, H. T. Inouye, S. K. Fiest, K. M. | J Am Geriatr Soc | 2020 |
Confusion Assessment Method for Intensive Care Unit (CAM-ICU) |
Effectiveness of an intensive care unit family education intervention on delirium knowledge: a pre-test post-test quasi-experimental study | Krewulak, K. D. Bull, M. J. Wesley Ely, E. Davidson, J. E. Stelfox, H. T. Fiest, K. M. | Can J Anaesth | 2020 |
Critical care |
Assessment and Management of Delirium in Critically Ill Veterans | Kresevic, D. M. Miller, D. Fuseck, C. W. Wade, M. Whitney, L. Conley, M. Rimac, J. Jacono, F. O'Leary-Wilson, H. L. Burant, C. J. | Critical care nurse | 2020 |
article |
Delirium Post-Stroke: Short- and Long-Term Effect on Depression, Anxiety, Apathy and Aggression (Research Study-Part of PROPOLIS Study) | Kowalska, K. Droś, J. Mazurek, M. Pasińska, P. Gorzkowska, A. Klimkowicz-Mrowiec, A. | J Clin Med | 2020 |
aggression |
Intrathecal Morphine Is Associated with Less Delirium Following Hip Fracture Surgery: A Register Study | Koning, M. V. van der Sijp, M. Stolker, R. J. Niggebrugge, A. | Anesth Pain Med | 2020 |
Delirium |
Evaluation of Pediatric Delirium Awareness and Management in Pediatric Intensive Care Units in Turkey | Konca, C. Anil, A. B. Küllüoglu, E. P. Luleyap, D. Anil, M. Tekin, M. | Journal of Pediatric Intensive Care | 2020 |
Awareness Delirium Management Pediatric Turkey |
Preventive effect of ramelteon on emergence agitation after general anaesthesia in paediatric patients undergoing tonsillectomy: a randomised, placebo-controlled clinical trial | Komazaki, M. Mihara, T. Nakamura, N. Ka, K. Goto, T. | Sci Rep | 2020 | |
Delirium in burn patients: developing a mobile application for assessment and diagnosis | Kolaei, N. M. M. Ayatollahi, H. Elyasi, F. | J Burn Care Res | 2020 |
Burn |
Delirium at the end of life | Knoepfel, S. Bode, L. Gehrke, S. Spiller, T. Fuchs, S. Ernst, J. von Känel, R. Boettger, S. | Palliat Support Care | 2020 |
Delirium at the end of life |
Protocol for the effectiveness of an anesthesiology control tower system in improving perioperative quality metrics and clinical outcomes: The tectonics randomized, pragmatic trial | King, C. R. Abraham, J. Kannampallil, T. G. Fritz, B. A. Abdallah, A. B. Chen, Y. Henrichs, B. Politi, M. Torres, B. A. Mickle, A. Budelier, T. P. McKinnon, S. Gregory, S. Kheterpal, S. Wildes, T. Avidan, M. S. Tectonics Research, Group | F1000Research | 2020 |
NCT02032030 |
Sleep disturbance and delirium in patients with acromegaly in the early postoperative period after transsphenoidal pituitary surgery | Kim, S. H. Kim, N. Min, K. T. Kim, E. H. Oh, H. Choi, S. H. | Medicine (Baltimore) | 2020 |
Acromegaly/ surgery |
Frontal electroencephalogram activity during emergence from general anaesthesia in children with and without emergence delirium | Kim, J. Lee, H. C. Byun, S. H. Lim, H. Lee, M. Choung, Y. Kim, E. | Br J Anaesth | 2020 |
brain waves |
Safety and efficacy of pharmacologic agents used for rapid tranquilization of emergency department patients with acute agitation or excited delirium | Kim, H. K. Leonard, J. B. Corwell, B. N. Connors, N. J. | 2020 |
acute agitation |
|
Effect of Timing of Intravenous Fentanyl Administration on the Incidence of Posttonsillectomy Nausea and Vomiting | Kim, H. J. Kim, M. S. Kim, H. Y. Park, W. K. Kim, W. S. Kim, S. Kim, H. J. | Laryngoscope | 2020 |
Postoperative nausea and vomiting |
Effect on Quality of Care of a Delirium Prevention Campaign for Surgical Intensive Care Nurses | Kim, H. Lee, S. M. | Publish Ahead of Print | 2020 | |
Ultrasound-Guided Pecto-Intercostal Fascial Block for Postoperative Pain Management in Cardiac Surgery: A Prospective, Randomized, Placebo-Controlled Trial | Khera, T. Murugappan, K. R. Leibowitz, A. Bareli, N. Shankar, P. Gilleland, S. Wilson, K. Oren-Grinberg, A. Novack, V. Venkatachalam, S. Rangasamy, V. Subramaniam, B. | J Cardiothorac Vasc Anesth | 2020 |
3-minute diagnostic Confusion Assessment Method |
Delirium Incidence, Duration, and Severity in Critically Ill Patients With Coronavirus Disease 2019 | Khan, S. H. Lindroth, H. Perkins, A. J. Jamil, Y. Wang, S. Roberts, S. Farber, M. Rahman, O. Gao, S. Marcantonio, E. R. Boustani, M. Machado, R. Khan, B. A. | Crit Care Explor | 2020 |
brain diseases |
Delirium, Cerebral Perfusion and High Frequency Vital Sign Monitoring in the Critically Ill: The CONFOCAL-2 Feasibility Study | Khan, J. M. Wood, M. D. Lee, K. F. H. Maslove, D. Muscedere, J. English, S. W. Ball, I. Slessarev, M. Boyd, J. G. | Annals of the American Thoracic Society | 2020 |
NCT03141619 |
Melatonin for delirium prevention in hospitalized patients: A systematic review and meta-analysis | Khaing, K. Nair, B. R. | J Psychiatr Res | 2020 |
Delirium |
Delirium in Older Patients With COVID-19 Presenting to the Emergency Department | Kennedy, M. Helfand, B. K. I. Gou, R. Y. Gartaganis, S. L. Webb, M. Moccia, J. M. Bruursema, S. N. Dokic, B. McCulloch, B. Ring, H. Margolin, J. D. Zhang, E. Anderson, R. Babine, R. L. Hshieh, T. Wong, A. H. Taylor, R. A. Davenport, K. Teresi, B. Fong, T. | JAMA Netw Open | 2020 |
Aged |
Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: A prospective observational study of delirium in elderly cardiac surgical patients | Kendall Smith, S. Nguyen, T. Labonte, A. K. Kafashan, M. Hyche, O. Guay, C. S. Wilson, E. Chan, C. W. Luong, A. Brian Hickman, L. Fritz, B. A. Emmert, D. Graetz, T. J. Melby, S. J. Lucey, B. P. Ju, Y. E. S. Wildes, T. S. Avidan, M. S. Palanca, B. J. A. | BMJ Open | 2020 |
aged |
Prevalence of Geriatric Syndromes and the Need for Hospice Care in Older Patients of the Emergency Department: A Study in an Asian Medical Center | Ke, Y. T. Peng, A. C. Shu, Y. M. Chung, M. H. Tsai, K. T. Chen, P. J. Weng, T. C. Hsu, C. C. Lin, H. J. Huang, C. C. | Emergency Medicine International | 2020 |
advance care planning |
The Role of Inflammation after Surgery for Elders (RISE) study: Examination of [11C]PBR28 binding and exploration of its link to post-operative delirium | Katsumi, Y. Racine, A. M. Torrado-Carvajal, A. Loggia, M. L. Hooker, J. M. Greve, D. N. Hightower, B. G. Catana, C. Cavallari, M. Arnold, S. E. Fong, T. G. Vasunilashorn, S. M. Marcantonio, E. R. Schmitt, E. M. Xu, G. Libermann, T. A. Barrett, L. F. Inouy | NeuroImage: Clinical | 2020 |
PET-MRI scanner |
Association between visitation restriction during the COVID-19 pandemic and delirium incidence among emergency admission patients: a single-center retrospective observational cohort study in Japan | Kandori, K. Okada, Y. Ishii, W. Narumiya, H. Maebayashi, Y. Iizuka, R. | Journal of Intensive Care | 2020 |
adult |
Intensive Care Unit Nurses’ Beliefs About Delirium Assessment and Management | Kimberly J. Oosterhouse, RN, PhD Catherine Vincent, RN, PhD Marquis D. Foreman, RN, PhD Valerie A. Gruss, PhD, APRN Colleen Corte, RN, PhD Barbara Berger, RN, PhD | AACN Adv Crit Care | 2016 |
beliefs; critical care nurses; delirium; older adult; vignettes |
Using Concept Unique Identifiers to Filter Electronic Health Records for Delirium Cases | Kimberly J. Oosterhouse, PhD, RN, Cynthia D. Young, MSN, RN, Manushi Desai, MBA, RN, Steven Birch, BS, Ron Price, Jr, BA, Kathleen L. Bobay, PhD, RN, FAAN | CIN: Computers, Informatics, Nursing | 2021 |
Concept unique identifiers, Delirium, |
Delirium incidence, risk factors, and treatments in older adults receiving chemotherapy: A systematic review and meta-analysis | Jung, P. Puts, M. Frankel, N. Syed, A. T. Alam, Z. Yeung, L. Malik, U. Rosario, C. Ayala, A. P. Hudson, J. Alibhai, S. M. H. | J Geriatr Oncol | 2020 |
Aged |
Postoperative delirium: perioperative assessment, risk reduction, and management | Jin, Z. Hu, J. Ma, D. | Br J Anaesth | 2020 |
Blood Transfusion |
Platelet-to-lymphocyte ratio as a predictive index for delirium in critically ill patients: A retrospective observational study | Jiang, X. Shen, Y. Fang, Q. Zhang, W. Cheng, X. | Medicine (Baltimore) | 2020 |
Aged |
Validation of the 3-minute diagnostic interview for CAM-defined Delirium in Chinese older adults | Ji, M. Wang, J. Yang, X. Huang, Y. Xiao, Y. Wu, Y. | Geriatr Nurs | 2020 |
3d-cam |
Diagnostic Test Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis | Jeong, E. Park, J. Lee, J. | Int J Environ Res Public Health | 2020 |
4at |
Development and Evaluation of Clinical Practice Guideline for Delirium in Long-Term Care | Jeong, E. Park, J. Chang, S. O. | Int J Environ Res Public Health | 2020 |
aged |
Risk prediction of delirium in hospitalized patients using machine learning: An implementation and prospective evaluation study | Jauk, S. Kramer, D. Großauer, B. Rienmüller, S. Avian, A. Berghold, A. Leodolter, W. Schulz, S. | J Am Med Inform Assoc | 2020 |
Machine learning |
Objectively measured sleep fragmentation is associated with incident delirium in older hospitalized patients: Analysis of data collected from an randomized controlled trial | Jaiswal, S. J. Kang, D. Y. Wineinger, N. E. Owens, R. L. | J Sleep Res | 2020 |
actigraphy |
Incidence and predictors of delirium on the intensive care unit after acute myocardial infarction, insight from a retrospective registry | Jäckel, M. Zotzmann, V. Wengenmayer, T. Duerschmied, D. Biever, P. M. Spieler, D. von Zur Mühlen, C. Stachon, P. Bode, C. Staudacher, D. L. | Catheter Cardiovasc Interv | 2020 |
NuDesc |
Real-World Preventive Effects of Suvorexant in Intensive Care Delirium: A Retrospective Cohort Study | Izuhara, M. Izuhara, H. K. Tsuchie, K. Araki, T. Ito, T. Sato, K. Miura, S. Otsuki, K. Nagahama, M. Hayashida, M. Hashioka, S. Wake, R. Kimura, T. Tsumoto, S. Saito, Y. Inagaki, M. | J Clin Psychiatry | 2020 |
Adolescent |
Prognostic Value of Delirium in Patients With Acute Heart Failure in the Intensive Care Unit | Iwata, E. Kondo, T. Kato, T. Okumura, T. Nishiyama, I. Kazama, S. Ishihara, T. Kondo, S. Hiraiwa, H. Tsuda, T. Ito, M. Aoyama, M. Tanimura, D. Awaji, Y. Unno, K. Murohara, T. | Canadian Journal of Cardiology | 2020 |
acute heart failure |
Postoperative delirium after reconstructive surgery for oral tumor: a retrospective clinical study | Ishibashi-Kanno, N. Takaoka, S. Nagai, H. Okubo-Sato, M. Fukuzawa, S. Uchida, F. Yamagata, K. Yanagawa, T. Bukawa, H. | Int J Oral Maxillofac Surg | 2020 |
Delirium |