Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
How to deal with the consent of adults with cognitive impairment involved in European geriatric living labs?
Authors
Sacco, G. Noublanche, F. Blazek, F. Hue, C. Carballido, L. Asfar, M. Allain, P. Annweiler, C.
Year
2021
Journal
Philos Ethics Humanit Med
Abstract

BACKGROUND: Living labs are realistic environments designed to create links between technology developers and end-users (i.e. mostly older adults). Research in LLH (Living labs in health) covers a wide range of studies from non-interventional studies to CT (clinical trials) and should involve patients with neurocognitive disorders. However, the ethical issues raised by the design, development, and implementation of research and development projects in LLH have been the subject of only little interest thus far. OBJECTIVE: Our aim was to determine a pragmatic, ethical and regulatory correct approach to seek the informed consent of patients with neurocognitive disorders according to the different types of studies carried out in European LLH, with a focus on the French context. METHODS: A narrative review of regulatory texts and clinical articles was conducted, and a pragmatic procedure to determine the decision-making capacity of older adults in LLH was proposed. RESULTS: Individuals must be adequately informed and freely agree to participate in CT. The capacity to consent should be assessed in CT including cognitively impaired older adults. We propose the following steps: first to assess for delirium using the 4 ‘A’s Test (4AT) or the 3-min Diagnostic interview for Confusion Assessment Method (3D-CAM), second to search for medical history of major neurocognitive disorder, and third to assess the decision capacity using the University of California, San Diego Brief Assessment of Capacity to Consent (UBACC). CONCLUSIONS: Including individuals with neurocognitive disorders in research implies using an efficient and pragmatic strategy to inform participants and obtain their consent. The tool we offer here may be useful in the routine operation of LLH but can also be extended to all CT with this population.

PMID

PMC8207703

Keywords

Aged
*Cognitive Dysfunction
Confusion
Humans
*Informed Consent
*Consent
*Ethics
*Geriatrics
*Living lab

Page(s)
Issue

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit Lee, H. J. Bae, E. Lee, H. Y. Lee, S. M. Lee, J. Acute Crit Care 2021

delirium
intensive care unit
light

Knowledge, barriers, and training needs of nurses working in delirium care Lee, G. Roh, Y. S Nurs Crit Care 2021

barrier
delirium
knowledge
nurse
performance

Causes and Predictors of 30-Day Readmission in Elderly Patients With Delirium Lau, H. L. Patel, S. D. Garg, N. Neurol Clin Pract 2021

Readmission rate, Delirium, Hospitalization, Length of stay, Post discharge care

Comparison of Antipsychotics for the Treatment of Patients With Delirium and QTc Interval Prolongation: A Clinical Decision Analysis Kurisu, K. Yoshiuchi, K. Front Psychiatry 2021

QTc prolongation
antipsychotics
clinical decision analysis
delirium
quetiapine
or financial relationships that could be construed as a potential conflict of
interest.

The Polish Version of the Nursing Delirium Screening Scale (NuDESC PL)-Experience of Using in Nursing Practice in Cardiac Surgery Intensive Care Unit Krupa, S. Dorota, O. Friganovic, A. Mędrzycka-Dąbrowska, W. Jurek, K. Int J Environ Res Public Health 2021

Cardiac Surgical Procedures/adverse effects
*Delirium/diagnosis
Humans
Intensive Care Units
*Nurses
Poland
*delirium
*disorientation
*nursing delirium screening scale
*screening

Associations of delirium with urinary tract infections and asymptomatic bacteriuria in adults aged 65 and older: A systematic review and meta-analysis Krinitski, D. Kasina, R. Klöppel, S. Lenouvel, E. J Am Geriatr Soc 2021

asymptomatic bacteriuria
delirium
urinary tract infection

Prevalence and Factors Affecting Postoperative Delirium in a Neurosurgical Intensive Care Unit Kose, G. Şirin, K. Inel, M. B. Mertoglu, S. Aksakal, R. Kurucu, Ş J Neurosci Nurs 2021

Cross-Sectional Studies
*Delirium
Humans
*Intensive Care Units
*Neurosurgery
Postoperative Complications
Prevalence
Prospective Studies
Risk Factors

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Kong, S. Wang, J. Xu, H. Wang, K. Oncotarget 2021

hypertension
oral tumor surgery
postoperative delirium
the elderly
respect to the research, authorship and/or publication of this article.

Perioperative Electroencephalogram Spectral Dynamics Related to Postoperative Delirium in Older Patients Koch, S. Windmann, V. Chakravarty, S. Kruppa, J. Yürek, F. Brown, E. N. Winterer, G. Spies, C. Anesth Analg 2021

Electroencephalography, Postoperative delirium, Surgery, Spectral edge frequency

Is dislocation following total hip arthroplasty caused while suffering from delirium? Kobayashi, T. Morimoto, T. Sonohata, M. Mawatari, M. Nagoya J Med Sci 2021

dislocation
postoperative delirium
total hip arthroplasty

Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study Kinoshita, H. Saito, J. Takekawa, D. Ohyama, T. Kushikata, T. Hirota, K. PLoS One 2021

Postoperative delirium, ICU delirium, Neutrophil-lymphocyte ratio, Surgery, Length of Stay

Delirium risk of histamine-2 receptor antagonists and proton pump inhibitors: A study based on the adverse drug event reporting database in Japan Kikkawa, N. Sogawa, R. Monji, A. Sumi, S. Murakawa-Hirachi, T. Kubo, T. Eguchi, Y. Miyamoto, Y. Kamo, M. Tobita, S. Yukawa, M. Uchida, R. Egoshi, M. Shimanoe, C. Gen Hosp Psychiatry 2021

Delirium
Histamine-2 receptor antagonist
Proton pump inhibitor

Delirium in neurosurgery: a systematic review and meta-analysis Kappen, P. R. Kakar, E. Dirven, C. M. F. van der Jagt, M. Klimek, M. Osse, R. J. Vincent, Apje Neurosurg Rev 2021

Delirium
Incidence rates
Neurosurgery
Screening tools

Risk factors for postoperative delirium and subsyndromal delirium in older patients in the surgical ward: A prospective observational study Kanno, M. Doi, M. Kubota, K. Kanoya, Y. PLoS One 2021

Postoperative delirium, Subsyndromal delirium, Surgery, CAM

Diagnostic accuracy and clinical applicability of the Swedish version of the 4AT assessment test for delirium detection, in a mixed patient population and setting Johansson, Y. A. Tsevis, T. Nasic, S. Gillsjö, C. Johansson, L. Bogdanovic, N. Kenne Sarenmalm, E BMC Geriatr 2021

Aged
*Delirium/diagnosis/epidemiology
Geriatric Assessment
Humans
Reproducibility of Results
Sensitivity and Specificity
Sweden/epidemiology
*4at
*Applicability
*Delirium
*Diagnostic accuracy
*Qualitative content analysis
*Validation study

In-Hospital Delirium as a Prognostic Factor for New Cognitive Disorder in a 1-Year Post-Hip Fracture Follow-Up Jaatinen, R. Luukkaala, T. Hongisto, M. T. Helminen, H. Nuotio, M. S. Dement Geriatr Cogn Disord 2021

Cognition
Delirium
Hip fracture
Outcome
Prognosis

Italian version of the short 10/66 dementia diagnostic schedule: a validation study Ibnidris, A. Piumatti, G. Carlevaro, F. Fadda, M. Magno, F. Magistro, D. Albanese, E. BMJ Open 2021

Aged
Cross-Sectional Studies
*Dementia/diagnosis
Female
Humans
Italy/epidemiology
Male
Middle Aged
ROC Curve
Switzerland
*delirium & cognitive disorders
*dementia
*old age psychiatry

A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study Hur, S. Ko, R. E. Yoo, J. Ha, J. Cha, W. C. Chung, C. R. JMIR Med Inform 2021

clinical prediction
delirium
electronic health record
intensive care unit
machine learning

The effect of evidence-based cluster nursing intervention on the incidences of delirium and the prognoses of ICU patients Huang, S. Xu, J. Du, Y. Wang, Y. Wei, H. Wei, G. Hu, M. Am J Transl Res 2021

Evidence-based medicine
Icu
cluster nursing intervention
delirium
prognosis

Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled tria Hong, H. Zhang, D. Z. Li, M. Wang, G. Zhu, S. N. Zhang, Y. Wang, D. X. Sessler, D. I. BMC Anesthesiol 2021

Delirium
Dexmedetomidine
Elderly
Orthopedic Procedures
Postoperative Period

Effects of a simulation-based education programme on delirium care for critical care nurses: A randomized controlled trial Ho, M. H. Yu, L. F. Lin, P. H. Chang, H. R. Traynor, V. Huang, W. C. Montayre, J. Chen, K. H. J Adv Nurs 2021

Clinical Competence
Critical Care
*Delirium
Humans
*Nurses
Taiwan
competence
confidence
delirium
knowledge
nurses
simulation

Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium Ho, M. H. Nealon, J. Igwe, E. Traynor, V. Chang, H. R. Chen, K. H. Montayre, J. Worldviews Evid Based Nurs 2021

Aged
Checklist
Cohort Studies
*Delirium/epidemiology/etiology
Humans
Incidence
Risk Factors
data pooling
epidemiology
geriatrics
gerontology
healthcare outcomes
meta-analysis
nervous system diseases
neurology
patient outcomes

Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N. Am J Geriatr Psychiatry 2021
Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients Heinrich, M. Sieg, M. Kruppa, J. Nürnberg, P. Schreier, P. H. Heilmann-Heimbach, S. Hoffmann, P. Nöthen, M. M. Janke, J. Pischon, T. Slooter, A. J. C. Winterer, G. Spies, C. D. BMC Med Genomics 2021

Chrm2
Chrm4
Genome-wide association study
Neurocognitive disorder

Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury Hansen, P. M. Lauridsen, J. T. Frandsen, N. S. Dan Med J 2021

*Brain Injuries
*Delirium/etiology
Glasgow Coma Scale
Humans
*Neurological Rehabilitation
*Stroke

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis Han, Q. Y. C. Rodrigues, N. G. Klainin-Yobas, P. Haugan, G. Wu, X. J Am Med Dir Assoc 2021

Dementia
delirium
delirium superimposed on dementia
meta-analysis
older adults
prevalence
risk factors

Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study Guan, H. L. Liu, H. Hu, X. Y. Abdul, M. Dai, M. S. Gao, X. Chen, X. F. Zhou, Y. Sun, X. Zhou, J. Li, X. Zhao, Q. Zhang, Q. Q. Wang, J. Han, Y. Cao, J. L. CNS Neurosci Ther 2021

delirium
elderly patient
the blood-brain barrier
urinary albumin creatinine ratio

Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery Goldstein, D. P. Blasco, M. de Almeida, J. Su, J. Xu, W. Cohen, M. Sklar, M. Alibhai, S Otolaryngol Head Neck Surg 2021

clock draw test
cognitive impairment
delirium
head neck surgery
older patients

What prompts patients to present with delirium? Gibb, K. Krywonos, A. Shah, R. Jha, A. Davis, D. Eur Geriatr Med 2021

Adult
Aged, 80 and over
Caregivers
*Delirium/diagnosis
Hospitalization
Humans
Surveys and Questionnaires
*Awareness
*Delirium
*Recognition
*Response

Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit Fu, Z. Xu, Q. Zhang, C. Bai, H. Chen, X. Zhang, Y. Luo, W. Lin, G. Int J Gen Med 2021

acute Stanford type A aortic dissection
intensive care unit
major surgery
post-operative delirium
systolic blood pressure

Postoperative Delirium in Patients After Brain Tumor Surgery French, J. Weber, T. Ge, B. Litofsky, N. S. World Neurosurg 2021

Confusion assessment method
Delirium
Recognition
Tumor resection

Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis Franks, Z. M. Alcock, J. A. Lam, T. Haines, K. J. Arora, N. Ramanan, M. Ann Am Thorac Soc 2021

Adult
*Critical Illness
Humans
Intensive Care Units
Randomized Controlled Trials as Topic
Restraint, Physical
*Stress Disorders, Post-Traumatic/etiology/prevention & control
Survivors
*critical care
*delirium
*physical restraint
*post-traumatic stress disorder
*post–intensive care syndrome

Long-Term Outcomes in ICU Patients with Delirium: A Population-based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

Adolescent
Adult
Aged
Aged, 80 and over
Alberta/epidemiology
Critical Illness
Delirium/*mortality
Facilities and Services Utilization/*statistics & numerical data
Female
Follow-Up Studies
Humans
*Intensive Care Units
Male
Middle Aged
Patient Discharge
Prognosis
Propensity Score
Retrospective Studies
Survival Analysis
Young Adult
*critical care
*delirium
*mortality

The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial Fazlollah, A. Babatabar Darzi, H. Heidaranlu, E. Moradian, S. T. Complement Ther Med 2021

*Cardiac Surgical Procedures/adverse effects
*Delirium/etiology/therapy
Humans
*Massage
*Musculoskeletal Manipulations
Sleep
*Sleep Wake Disorders/etiology/therapy
Cardiac surgical procedure
Delirium
Massage
Pain measurement
Sleep hygiene

A delirium prevalence audit and a pre and post evaluation of an interprofessional education intervention to increase staff knowledge about delirium in older adults Ewens, B. Seaman, K. Whitehead, L. Towell-Barnard, A. Young, M. BMC Nurs 2021

Delirium
Delirium assessment
Delirium knowledge
Interprofessional education, quality improvement
Symptom recognition

Anaesthetic depth and delirium after major surgery: a randomised clinical trial Evered, L. A. Chan, M. T. V. Han, R. Chu, M. H. M. Cheng, B. P. Scott, D. A. Pryor, K. O. Sessler, D. I. Veselis, R. Frampton, C. Sumner, M. Ayeni, A. Myles, P. S. Campbell, D. Leslie, K. Short, T. G. Br J Anaesth 2021

anaesthesia
bispectral index
cognitive dysfunction
delirium
electroencephalography
postoperative delirium

Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients Esmaeeli, S. Franco-Garcia, E. Akeju, O. Heng, M. Zhou, C. Azocar, R. J. Quraishi, S. A. Aging Clin Exp Res 2021

Cognition
Delirium
Frailty
Postoperative delirium
Trauma

Prevention of postoperative delirium after cardiovascular surgery: A team-based approach Enomoto, K. Kosaka, S. Kimura, T. Matsubara, M. Kitada, Y. Mieno, M. Okamura, H. J Thorac Cardiovasc Surg 2021

Delirium Team Approach program
benzodiazepine
cardiovascular surgery
postoperative delirium

Serum Levels of S100β, Neuron-Specific Enolase, Glial Fibrillary Acidic Protein in Kidney Transplant Recipients and Donors: A Prospective Cohort Study Dinc, B. Yılmaz, V. T. Aslan, M. Aycan, I. O. Kiraz, N. Kisaoglu, A. Dandin, O. Hadimioglu, N. Ertug, Z. Transplant Proc 2021

Nephrectomy, Kidney transplant, Neuromarkers, Postoperative delirium

Delirium and Its Pharmacological Causes in Older People, Part 1 DeMaagd, G. A. DeMaagd, D. R. Philip, A. Coalter, C. F. Sr Care Pharm 2021

Aged
*Delirium/chemically induced/diagnosis/epidemiology
Human

Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes Delgado, J. Jones, L. Bradley, M. C. Allan, L. M. Ballard, C. Clare, L. Fortinsky, R. H. Hughes, C. M. Melzer, D. Age Ageing 2021

Aged
Aged, 80 and over
*Dementia/diagnosis/drug therapy/epidemiology
England/epidemiology
Humans
*Inappropriate Prescribing
Incidence
Multimorbidity
Outcome Assessment, Health Care
Potentially Inappropriate Medication List
Retrospective Studies
*Alzheimer’s
*Beer’s
*Parkinson’s
*delirium
*hospitalisation
*misprescribing
*mortality
*older people
*vascular dementia

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients Delaney, L. J. Litton, E. Van Haren, F. Crit Care Nurs Clin North Am 2021

Critical Care
*Delirium/epidemiology
Humans
Intensive Care Units
Sleep
*Sleep Wake Disorders/epidemiology
Delirium
Intensive care
Light
Noise
Sleep disturbance

Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer De León, L. E. Rochefort, M. M. Bravo-Iñiguez, C. E. Fox, S. W. Tarascio, J. N. Cardin, K. DuMontier, C. Frain, L. N. Jaklitsch, M. T. J Geriatr Oncol 2021

Aged
Humans
Length of Stay
*Lung Neoplasms/surgery
Morbidity
Postoperative Complications/epidemiology
*Quality Improvement
Retrospective Studies
Thoracic Surgery, Video-Assisted
Thoracotomy
*Lobectomy
*Minimally invasive surgery
*Morbidity
*Older adult
*Oncology outcomes
*Postoperative outcomes
*Thoracic surgery

Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study de Araujo, C. Z. S. de Araújo, L. Z. S. Nassar Junior, A. P. Palliat Support Care 2021

Cancer
Cancer care facilities
Deep sedation
End-of-life care
Palliative care

Development and Implementation of a Multicomponent Protocol to Promote Sleep and Reduce Delirium in a Medical Intensive Care Unit Darby, A. Northam, K. Austin, C. A. Chang, L. Campbell-Bright, S Ann Pharmacother 2021

critical care
mechanical ventilators
quality assurance
sedatives
sleep disorders

Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors Damoiseaux-Volman, B. A. van der Velde, N. Ruige, S. G. Romijn, J. A. Abu-Hanna, A. Medlock, S. JMIR Med Inform 2021

aged
clinical decision support systems
geriatrics
hospital
quality of care

Sevoflurane-Remifentanil Versus Propofol-Remifentanil Anesthesia During Noncardiac Surgery for Patients with Coronary Artery Disease - A Prospective Study Between 2016 and 2017 at a Single Center Dai, Z. Lin, M. Li, Y. Gao, W. Wang, P. Lin, J. Wan, Z. Jiang, Y. Med Sci Monit 2021

Acute Coronary Syndrome, Coronary Artery Disease, Propofol

Symptom trajectories for palliative care inpatients with and without hyperactive delirium in the last week of life Dai, Y. Walpole, G. Ding, J. Scanlon, C. Ho, L. Khoo, R. H. Huang, C. Cook, A. William, L. Johnson, C. E. J Adv Nurs 2021

end of life
hyperactive delirium
inpatient palliative care
nurse caring
symptom trajectory

Subtypes of delirium after ischaemic stroke-predisposing factors and outcomes: a prospective observational study (PROPOLIS) Czyzycki, M. Klimiec-Moskal, E. Chrobak, A. A. Pera, J. Slowik, A. Dziedzic, T. Eur J Neurol 2021

delirium
motor subtypes
neuropsychiatric disturbances
outcome
stroke

Effectiveness of a Delirium Prevention Initiative on an Inpatient Neuroscience Unit Cyrus, T. Wenthold, R. Hall, B. Tu, L. Hedquist, K. Omodt, J. Kozub, E. Guthrie, P. F. J Neurosci Nurs 2021

Clinical Competence
*Delirium/prevention & control
Humans
Inpatients
*Nurses
Quality Improvement

Association Between Cerebral Desaturation and Postoperative Delirium in Thoracotomy With One-Lung Ventilation: A Prospective Cohort Study Cui, F. Zhao, W. Mu, D. L. Zhao, X. Li, X. Y. Wang, D. X. Jia, H. Q. Dai, F. Meng, L. Anesth Analg 2021

Aged
Cerebrovascular Circulation/*physiology
Cohort Studies
Delirium/diagnosis/*etiology/physiopathology
Female
Humans
Male
Middle Aged
One-Lung Ventilation/*adverse effects/trends
Postoperative Cognitive Complications/diagnosis/*etiology/physiopathology
Prospective Studies
Thoracotomy/*adverse effects/trends

Factors for Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study Corli, O. Santucci, C. Uggeri, S. Bosetti, C. Cattaneo, M. Ermolli, D. Varrassi, G. Myrcik, D. Paladini, A. Rekatsina, M. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Beretta, M. Adv Ther 2021

*Delirium/chemically induced/diagnosis/epidemiology
Hospitalization
Humans
*Palliative Care
Proportional Hazards Models
Prospective Studies
Risk Factors
*Causality
*Clinical predisposing factors
*Delirium

A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study Cooter Wright, M. Bunning, T. Eleswarpu, S. S. Heflin, M. T. McDonald, S. R. Lagoo-Deenadalayan, S. Whitson, H. E. Martinez-Camblor, P. Deiner, S. G. Berger, M. Anesth Analg 2021

age factors, anesthesia, methods, delirium, surgery/prevention & control, Electroencephalography, drug effects

Implementation and Routinization of the ABCDE Bundle: A Mixed Methods Evaluation Collinsworth, A. W. Brown, R. Cole, L. Jungeblut, C. Kouznetsova, M. Qiu, T. Richter, K. M. Smith, S. Masica, A. L. Dimens Crit Care Nurs 2021

Adult
Critical Care
*Delirium
Humans
Intensive Care Units
Respiration, Artificial
Surveys and Questionnaires

Prediction of delirium using data mining: A systematic review Chua, S. J. Wrigley, S. Hair, C. Sahathevan, R J Clin Neurosci 2021

Area Under Curve
Data Mining
*Delirium/diagnosis/epidemiology
Humans
Length of Stay
Retrospective Studies
Association mining
Big data
Delirium
Machine learning
Systematic review
competing financial interests or personal relationships that could have appeared to
influence the work reported in this paper.

Determinants of Non-emergency Use of Control Interventions in Older Canadian Psychiatric Inpatients: Analysizing the InterRAI Mental Health Electronic Health Records Cheung, G. Mah, T. M. Barak, Y. Hirdes, J. P. Front Psychiatry 2021

aggression
control interventions
delirium
geriatric psychiatry
restraints
or financial relationships that could be construed as a potential conflict of
interest.

Assessment of preoperative frailty and identification of patients at risk for postoperative delirium in cardiac intensive care units: a prospective observational study Cheng, H. W. Liu, C. Y. Chen, Y. S. Shih, C. C. Chen, W. Y. Chiou, A. F. Eur J Cardiovasc Nurs 2021

Anxiety
Arrhythmia
Cardiac surgery
Delirium
Depression
Frailty

Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty Chen, J. Zheng, C. Zhong, J. Zhao, G. Shi, J. Huang, G. Wei, Y. Wang, S. Yu, J. Xia, J. BMC Musculoskelet Disord 2021

Aged
Arthroplasty
*Delirium/diagnosis/epidemiology/etiology
Humans
*Nutrition Assessment
Prognosis
Retrospective Studies
Malnutrition
Postoperative delirium
Prognostic nutritional index
Risk factor
Total joint arthroplasty

Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery CheheiliSobbi, S. Peters van Ton, A. M. Wesselink, E. M. Looije, M. F. Gerretsen, J. Morshuis, W. J. Slooter, A. J. C. Abdo, W. F. Pickkers, P. van den Boogaard, M. J Cardiothorac Surg 2021

*Cardiac Surgical Procedures/adverse effects
Case-Control Studies
Cytokines
*Delirium/etiology
Humans
Prospective Studies
Tumor Necrosis Factor-alpha
Cardiothoracic surgery
Delirium
Immunity
Intensive care medicine

Diagnostic accuracy of the "4 A's Test" delirium screening tool for the postoperative cardiac surgery ward Chang, Y. Ragheb, S. M. Oravec, N. Kent, D. Nugent, K. Cornick, A. Hiebert, B. Rudolph, J. L. MacLullich, A. M. J. Arora, R. C. J Thorac Cardiovasc Surg 2021

4at
cardiac surgery
nursing
postoperative delirium

Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework Chan, C. K. Song, Y. Greene, R. Lindroth, H. Khan, S. Rios, G. Khan, B. Wang, S Am J Crit Care 2021

Alzheimer Disease
Biomarkers
*Delirium/diagnosis
Humans
*Intensive Care Units
National Institute on Aging (U.S.)
United States

Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study Casault, C. Soo, A. Lee, C. H. Couillard, P. Niven, D. Stelfox, T. Fiest, K. BMJ Open 2021

Adult
Alberta
Cohort Studies
*Delirium/chemically induced/epidemiology
Female
Humans
Hypnotics and Sedatives/adverse effects
*Intensive Care Units
Length of Stay
Male
Middle Aged
Propensity Score
Respiration, Artificial
Retrospective Studies
*adult intensive & critical care
*delirium & cognitive disorders
*health & safety
*quality in health care

Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. Rev Clin Esp (Barc) 2021

Atención continuada
Continued care
Fractura de cadera
Hip fracture
Internal Medicine
Medicina Interna
Orthogeriatrics
Ortogeriatría

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis Burry, L. D. Cheng, W. Williamson, D. R. Adhikari, N. K. Egerod, I. Kanji, S. Martin, C. M. Hutton, B. Rose, L. Intensive Care Med 2021

Adult
Bayes Theorem
*Critical Illness
*Delirium/prevention & control
Humans
Network Meta-Analysis
Randomized Controlled Trials as Topic
Respiration, Artificial/adverse effects
*Critical care
*Delirium
*Non-pharmacological interventions
*Pharmacological
*Prevention
financial relationships with any organizations that might have an interest in the
submitted work in the previous 3 years
no other relationships or activities that
could appear to have influenced the submitted work. BH has previously provided
methodologic advice to Eversana Inc for the conduct of systemic reviews and
meta-analysis on unrelated topics.

Dexmedetomidine for Facilitating Mechanical Ventilation Extubation in Difficult-to-Wean ICU Patients: Systematic Review and Meta-Analysis of Clinical Trials Buckley, M. S. Smithburger, P. L. Wong, A. Fraser, G. L. Reade, M. C. Klein-Fedyshin, M. Ardiles, T. Kane-Gill, S. L. J Intensive Care Med 2021

Adult
Airway Extubation
Critical Care
*Dexmedetomidine
Humans
Intensive Care Units
Length of Stay
*Respiration, Artificial
agitation
delirium
dexmedetomidine
extubation
intensive care
mechanical ventilation
weaning

Risk factors for postoperative delirium: An umbrella review of systematic reviews Bramley, P. McArthur, K. Blayney, A. McCullagh, I. Int J Surg 2021

*Cognitive Dysfunction
*Delirium/epidemiology/etiology
Humans
Length of Stay
Postoperative Complications/epidemiology/etiology
Risk Factors
Systematic Reviews as Topic
Delirium
Prognostic
Risk factor
Surgery
Umbrella review

Inadequate emergence after anesthesia for elective cancer surgery: a single-center cohort study Braga, A. Abelha, F. Braz J Anesthesiol 2021

Cancer surgeries
Emergence delirium
Hypoactive emergence
Inadequate emergence
Quality of recovery

Asthma and delirium episodes during hospitalization Bozek, A. Fiolka, R. Zajac, M. Aging Med (Milton) 2021

asthma
delirium

A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU Boyd, C. Hassig, T. MacLaren, R. Pharmacotherapy 2021

critical illness
delirium
histamine H2 antagonists
mortality
peptic ulcer prevention and control
proton pump inhibitors
stress

Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. Stroke 2021

MRI, functional
attention
basal ganglia
delirium
incidence
ischemic stroke
prevalence

Preventing Delirium and Promoting Long-Term Brain Health: A Clinical Trial Design for the Perioperative Cognitive Enhancement (PROTECT) Trial Atkins, K. J. Scott, D. A. Silbert, B. Pike, K. E. Evered, L. J Alzheimers Dis 2021

Anesthesia and analgesia
cognition
delirium
dementia
healthy aging
perioperative medicine
prehabilitation
preventive medicine
rehabilitation

Prevalence of Severe Neurocognitive Impairment and Its Association with Socio-Demographics and Functionality Among Ugandan Older Persons: A Hospital-Based Study Atim, L. M. Kaggwa, M. M. Mamun, M. A. Ashaba, S. Maling, S. Clin Interv Aging 2021

Aged
Aged, 80 and over
*Cognition Disorders
Cross-Sectional Studies
Female
Hospitals
Humans
Male
Middle Aged
Prevalence
Uganda/epidemiology
Barthel Index
Mini-Mental Status Examination
Ugandan elderly
dementia
early diagnosis
functionality
neurocognitive disorder
prevalence and associated factors

Clinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review Arantzamendi, M. Belar, A. Payne, S. Rijpstra, M. Preston, N. Menten, J. Van der Elst, M. Radbruch, L. Hasselaar, J. Centeno, C. J Pain Symptom Manage 2021

*Hospice and Palliative Care Nursing
Humans
Hypnotics and Sedatives/therapeutic use
Palliative Care
Prospective Studies
Retrospective Studies
*Terminal Care
*Palliative sedation
*deep sedation
*hospice care
*palliative care
*palliative medicine
*prospective studies
*sedation
*systematic review
*terminally ill

Psychometric Properties of Nursing Delirium Screening Scale in Patients Admitted to Intensive Care Units Amirajam, Z. Asadi-Noran, E. Molaei, B. Adiban, V. Heidarzadeh, M. Hassanpour-Darghah, M. Indian J Crit Care Med 2021

Delirium
Intensive care
Validity

Delirium researchers' perspectives of the challenges in delirium biomarker research: A qualitative study Amgarth-Duff, I. Hosie, A. Caplan, G. A. Agar, M. PLoS One 2021

Biomarkers/blood
Biomedical Research
Delirium/*blood
Female
Humans
Male
Qualitative Research
*Research Personnel

Addition of Valerian and Lemon Balm Extract to Quetiapine Reduces Agitation in Critically Ill Patients with Delirium: A Pilot Randomized Clinical Trial Alikiaie, B. Shahmoradi, E. Yekdaneh, A. Mousavi, S. Indian J Crit Care Med 2021

Delirium
Lemon balm
Quetiapine
Valerian

Spinal block and delirium in oncologic patients after laparoscopic surgery in the Trendelenburg position: A randomized controlled trial Mitsunaga, J. K. Junior Calsavara, V. F. Onari, E. S. Arantes, V. M. Akamine, C. P. Handa, A. M. Quezada, M. M. C. Ito, F. Y. Porto, A. C. S. Giroud Joaquim, E. H. Nakamura, G. PLoS One 2021
Perioperative Vascular Biomarker Profiling in Elective Surgery Patients Developing Postoperative Delirium: A Prospective Cohort Study Menzenbach, J. Frede, S. Petras, J. Guttenthaler, V. Kirfel, A. Neumann, C. Mayr, A. Wittmann, M. Coburn, M. Klaschik, S. Hilbert, T. Biomedicines 2021

Ccl2
Mcp-1
biomarker
cardiac surgery
elective surgery
glycocalyx
postoperative delirium
vascular inflammation

Preliminary Study of Serum Biomarkers Associated With Delirium After Major Cardiac Surgery McKay, T. B. Rhee, J. Colon, K. Adelsberger, K. Turco, I. Mueller, A. Qu, J. Akeju, O. J Cardiothorac Vasc Anesth 2021

Fgf
cardiac surgery
cardiopulmonary bypass
cognition
delirium
fibroblast growth factor
inflammation
metabolism
neurodegeneration

Stratified delirium risk using prescription medication data in a state-wide cohort McCoy, T. H., Jr. Castro, V. M. Hart, K. L. Perlis, R. H. Gen Hosp Psychiatry 2021

Cohort study
Data mining
Delirium
Feature engineering
Pharmacovigilance
Predictive modeling

Nutritional Risk at intensive care unit admission and outcomes in survivors of critical illness Mart, M. F. Girard, T. D. Thompson, J. L. Whitten-Vile, H. Raman, R. Pandharipande, P. P. Heyland, D. K. Ely, E. W. Brummel, N. E. Clin Nutr 2021

Activities of daily living
Cognitive dysfunction
Critical illness
Nutrition assessment
Patient discharge
Quality of life

Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Kaenel, R. Boettger, S. Front Psychiatry 2021

comparison
delirium
prospective
risk factors
very old

Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W. J Cardiothorac Surg 2021

Adult
Aged
Aneurysm, Dissecting/ surgery
Aortic Aneurysm/ surgery
Area Under Curve
Biomarkers/blood
Delirium/ blood/etiology
Humans
Interleukin-6/ blood
Male
Middle Aged
Postoperative Complications/blood/etiology
ROC Curve
Retrospective Studies
Aortic dissection
Inflammatory cytokines
Interleukin-6
Postoperative delirium

Association of early and later depressive symptoms with functional outcome after ischemic stroke Lopatkiewicz, A. M. Pera, J. Slowik, A. Dziedzic, T. J Neural Transm (Vienna) 2021

Cognitive decline
Delirium
Depression
Outcome
Stroke

Development and validation of a postoperative delirium prediction model for pediatric patients: A prospective, observational, single-center study Lin, N. Liu, K. Feng, J. Chen, R. Ying, Y. Lv, D. Zhou, Y. Xu, H. Medicine (Baltimore) 2021

Adolescent
Anesthesia, General/ adverse effects/methods
Child
Child, Preschool
Developmental Disabilities/ epidemiology
Dexmedetomidine/administration & dosage/ adverse effects
Emergence Delirium/ epidemiology/etiology/prevention & control
Female
Humans
Hypnotics and Sedatives/administration & dosage/ adverse effects
Infant
Infant, Newborn
Logistic Models
Male
Prevalence
Prospective Studies
ROC Curve
Risk Assessment/methods/statistics & numerical data
Risk Factors

Patients' experiences of delirium: A systematic review and meta-summary of qualitative research Kuusisto-Gussmann, E. Höckelmann, C. von der Lühe, V. Schmädig, R. Baltes, M. Stephan, A. J Adv Nurs 2021

delirium
nursing
qualitative research
systematic review

Effects of case-based confusion assessment methods for intensive care unit training on delirium knowledge and delirium assessment accuracy of intensive care units: A quasi-experimental study Kim, Y. N. Kim, D. H. Nurse Educ Today 2021

Critical Illness
Delirium/diagnosis
Hospitals, University
Humans
Intensive Care Units
Republic of Korea
Assessment
Delirium
Education
Intensive care unit
Knowledge
Nursing

Bridging the Gap Between the Intensive Care Unit and the Acute Medical Care Unit Kim, E. Kast, C. Afroz-Hossain, A. Qiu, M. Pappas, K. Sinvani, L. Am J Crit Care 2021
Preoperative MRI brain phenotypes are related to postoperative delirium in older individuals Kant, I. M. J. Slooter, A. J. C. Jaarsma-Coes, M. van Montfort, S. J. T. Witkamp, T. D. Pasma, W. Hendrikse, J. de Bresser, J. Neurobiol Aging 2021

Brain phenotypes
Delirium
Encephalopathy
Mri

Pre-Existing Psychiatric Illness Is Associated With an Increased Risk of Delirium in Patients With Acute Respiratory Distress Syndrome Kalra, S. S. Jaber, J. Alzghoul, B. N. Hyde, R. Parikh, S. Urbine, D. Reddy, R. J Intensive Care Med 2021

Ards
acute respiratory distress syndrome
anxiety
delirium
depression
psychiatric illness

Development and internal validation of a predictive model of cognitive decline 36 months following elective surgery Jones, R. N. Tommet, D. Steingrimsson, J. Racine, A. M. Fong, T. G. Gou, Y. Hshieh, T. T. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Vasunilashorn, S. M. Abdeen, A. Earp, B. Kunze, L. Lange, J. Vlassakov, K. Dickerson, B. C. Marcantonio Alzheimers Dement (Amst) 2021

cognitive decline
delirium
machine learning
model prediction
post‐operative
statistical learning

The performance of the Dutch Safety Management System frailty tool to predict the risk of readmission or mortality in older hospitalised cardiac patients Jepma, P. Verweij, L. Tijssen, A. Heymans, M. W. Flierman, I. Latour, C. H. M. Peters, R. J. G. Scholte Op Reimer, W. J. M. Buurman, B. M. Ter Riet, G. BMC Geriatr 2021

Aged
Aged, 80 and over
Female
Frailty
Geriatric Assessment
Humans
Male
Netherlands/epidemiology
Patient Readmission
Prospective Studies
Risk Assessment
Risk Factors
Safety Management
Cardiovascular diseases
Mortality
Predictive value of tests

Outcomes of transcatheter aortic valve replacement in patients with cognitive dysfunction Jain, V. Kalra, A. Panhwar, M. S. Bansal, A. Nowacki, A. Bhatia, K. Gupta, T. Ineman, N. L. Khan, S. U. Krishnaswamy, A. Reed, G. W. Puri, R. Kapadia, S. R. Svensson, L. G. Kanaa, N. A. Lahorra, J. A. J Am Geriatr Soc 2021

cognitive impairment
dementia
outcomes
transcatheter aortic valve replacement

The Importance of Delirium and Delirium Prevention in Older Adults During Lockdowns Inouye, S. K. JAMA 2021

Aged
COVID-19/ psychology
Delirium/etiology/ prevention & control
Hospitalization
Humans
Infection Control
Inpatients/psychology
Physical Distancing

Association of Pain With Atrial Fibrillation and Delirium After Cardiac Surgery: A DECADE Sub-Study Ince, I. Chiu, A. Sagir, A. Chahar, P. Lin, J. Douglas, A. Adi, A. Fang, J. Mao, G. Turan, A. J Cardiothorac Vasc Anesth 2021

atrial fibrillation
delirium
pain

Higher versus lower mean arterial pressure target management in older patients having non-cardiothoracic surgery: A prospective randomized controlled trial Hu, A. M. Qiu, Y. Zhang, P. Zhao, R. Li, S. T. Zhang, Y. X. Zheng, Z. H. Hu, B. L. Yang, Y. L. Zhang, Z. J. J Clin Anesth 2021

Aged
Anesthesia, General/adverse effects
Arterial Pressure
Delirium/epidemiology/etiology/prevention & control
Female
Humans
Postoperative Complications/epidemiology/etiology/prevention & control
Prospective Studies
Elderly patients
General anaesthesia
Mean arterial pressure
Postoperative delirium

Are Patients Taking Benzodiazepines at Increased Risk for Complications Following Primary Total Knee Arthroplasty? Hernandez, N. M. Cunningham, D. J. Hinton, Z. W. Wu, C. J. Seyler, T. M. J Arthroplasty 2021

Arthroplasty, Replacement, Knee/adverse effects
Benzodiazepines/adverse effects
Humans
Joint Diseases
Odds Ratio
Postoperative Complications/chemically induced/epidemiology
Reoperation
Retrospective Studies
Risk Factors
benzodiazepines
complications
delirium
revision
total knee arthroplasty

Preoperative medication use and development of postoperative delirium and cognitive dysfunction Heinrich, M. Nottbrock, A. Borchers, F. Mörgeli, R. Kruppa, J. Winterer, G. Slooter, A. J. C. Spies, C. Clin Transl Sci 2021
Radiological, Chemical, and Pharmacological Cholinergic System Parameters and Neurocognitive Disorders in Older Presurgical Adults Heinrich, M. Müller, A. Lammers-Lietz, F. Borchers, F. Mörgeli, R. Kruppa, J. Zacharias, N. Winterer, G. Slooter, A. J. C. Spies, C. D. J Gerontol A Biol Sci Med Sci 2021

Anticholinergic medication
Cholinesterase
Cognition
Magnetic resonance imaging

Predictors and Sequelae of Postoperative Delirium in a Geriatric Patient Population With Hip Fracture Haynes, M. S. Alder, K. D. Toombs, C. Amakiri, I. C. Rubin, L. E. Grauer, J. N J Am Acad Orthop Surg Glob Res Rev 2021

Postoperative Delirium

Hip fracture

Dementia

Geriatric

Preoperative dementia