Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Impact of Delirium Onset and Duration on Mortality in Patients With Cancer Admitted to the ICU
Authors
Tao, J. Seier, K. P. Chawla, S. Tan, K. S. Wheeler, A. Sanzone, J. Marasigan-Stone, C. B. Simondac, J. S. Pascual, A. V. Kostelecky, N. T. Voigt, L. P.
Year
2024
Journal
J Intensive Care Med
Abstract

BACKGROUND: Little is known on the effects of delirium onset and duration on outcome in critically ill patients with cancer. OBJECTIVES: To determine the impact of delirium onset and duration on intensive care unit (ICU) and hospital mortality and length of stay (LOS) in patients with cancer. METHODS: Of the 915 ICU patients admitted in 2018, 371 were included for analysis after excluding for terminal disease, <24-h ICU stay, lack of active cancer and delirium. Delirium was defined as early if onset was within 2 days of ICU admission, late if onset was on day 3 or later, short if duration was 2 days or less, and long if duration was 3 days or longer. Patients were placed into 4 combination groups: early-short, early-long, late-short, and late-long delirium. Multivariate analysis controlling for sex, age, metastatic disease, and predelirium hospital LOS was performed to determine ICU and hospital mortality and LOS. Exploratory analysis of long-term survival was also performed. Restricted cubic splines were performed to confirm the use of 2 days to distinguish between early versus late onset and short versus long duration. RESULTS: A total of 32.9% (n = 122) patients had early-short, 39.1% (n = 145) early-long, 16.2% (n = 60) late-short, and 11.9% (n = 44) late-long delirium. Late-long delirium was independently associated with increased ICU (OR 4.45, CI 1.92-10.30; P < .001) and hospital (OR 2.91, CI 1.37-6.19; P = .005) mortality and longer ICU (OR 1.97, CI 1.58-2.47; P < .001) LOS compared to early-short delirium. Early delirium had better overall survival at 18 months than late delirium. Long-term survival further improved when delirium duration was 2 days or less. Prediction heatmaps confirm the use of a 2-day cutoff. CONCLUSION: Late delirium, especially with long duration, significantly worsens outcome in ICU patients with cancer and should be considered a harbinger of poor overall condition.

PMID

PMID: 38629453

Keywords

ICU outcomes
cancer
delirium
hospital mortality

Page(s)
Issue

Search:
Total Records Found: 6300, showing 100 per page
TitleAuthorsJournalYearKeywords
Comparison of Esophagectomy outcomes between a National Center, a National Audit Collaborative, and an International database using the Esophageal Complications Consensus Group (ECCG) standardized definitions Reynolds, J. V. Donlon, N. Elliott, J. A. Donohoe, C. Ravi, N. Kuppusamy, M. K. Low, D. E. Dis Esophagus 2021

Aged
Anastomotic Leak/epidemiology/etiology
Consensus
*Esophageal Neoplasms/surgery
*Esophagectomy/adverse effects
Female
Humans
Male
Postoperative Complications/epidemiology/etiology
Retrospective Studies
complications
esophageal cancers
esophagectomy

Health Profiles, Health Services Use, and Transition to Dementia in Inpatients With Late-Life Depression and Other Mental Illnesses Reppermund, S. Heintze, T. Srasuebkul, P. Trollor, J. N. J Am Med Dir Assoc 2021

Aged
Australia/epidemiology
*Dementia/epidemiology
Depression/epidemiology
Humans
*Inpatients
Length of Stay
Male
New South Wales
Retrospective Studies
Risk Factors
*Depression
*data linkage
*dementia
*mental disorders
*older adults

A Survey of Nurses' Perspectives on Delirium Screening in Older Adult Medical Inpatients With Limited English Proficiency Reppas-Rindlisbacher, C. Panov, E. D. Cuperfain, A. B. Rawal, S. J Gerontol Nurs 2021

Aged
*Delirium/diagnosis
Health Knowledge, Attitudes, Practice
Humans
Inpatients
*Limited English Proficiency
*Nurses

Post-hospital falls incidence and risk factors among older adults: a systematic review and meta-analysis Qian, X. X. Chen, Z. Fong, D. Y. T. Ho, M. Chau, P. H. Age Ageing 2021

incidence
meta-analysis
older population
post-hospital Falls
risk factors

The prevalence of serotonin syndrome in an intensive care unit: A prospective observational study Prakash, S. Rathore, C. Rana, K. J Crit Care 2021

Adult
Humans
Intensive Care Units
Male
Middle Aged
Prevalence
Prospective Studies
*Respiratory Insufficiency
*Serotonin Syndrome/chemically induced/diagnosis/epidemiology
*Cyproheptadine
*Serotonin syndrome
*Serotonin toxicity

Associations of subclinical heart failure and atrial fibrillation with mild cognitive impairment: a cross-sectional study in a subclinical heart failure screening programme Potter, E. L. Ramkumar, S. Wright, L. Marwick, T. H. BMJ Open 2021

Aged
*Atrial Fibrillation/diagnosis/epidemiology
Australia/epidemiology
*Cognitive Dysfunction/diagnosis/epidemiology
Cross-Sectional Studies
*Heart Failure
Humans
*delirium & cognitive disorders
*preventive medicine

A One-Day Prospective National Observational Study on Sedation-Analgesia of Patients with Brain Injury in French Intensive Care Units: The SEDA-BIP-ICU (Sedation-Analgesia in Brain Injury Patient in ICU) Study Poignant, S. Vigué, B. Balram, P. Biais, M. Carillon, R. Cottenceau, V. Dahyot-Fizelier, C. Degos, V. Geeraerts, T. Jeanjean, P. Vega, E. Lasocki, S. Espitalier, F. Laffon, M. Neurocrit Care 2021

Brain injury
Intensive care unit
Sedation-analgesia

Risk factors and adverse clinical outcomes of postoperative delirium in Thai elderly patients: A prospective cohort study Pipanmekaporn, T. Punjasawadwong, Y. Wongpakaran, N. Wongpakaran, T. Suwannachai, K. Chittawatanarat, K. Mueankwan, S. Perspect Psychiatr Care 2021

Aged
*Delirium/epidemiology
Humans
*Postoperative Complications/epidemiology
Prospective Studies
Risk Factors
Thailand/epidemiology
adverse clinical outcomes
elderly patients
mortality
postoperative delirium

Multifaceted intervention including Facebook-groups to improve guideline-adherence in ICU: A quasi-experimental interrupted time series study Petosic, A. Småstuen, M. C. Beeckman, D. Flaatten, H. Sunde, K. Wøien, H. Acta Anaesthesiol Scand 2021

agitation/sedation
delirium
facebook
guideline adherence
intensive care unit
interrupted time series
multifacetted intervention
pain
quality improvement
quasi experimental
social media
social networking sites

Perioperative Optimization of Senior Health in Spine Surgery: Impact on Postoperative Delirium Pernik, M. N. Deme, P. R. Nguyen, M. L. Aoun, S. G. Adogwa, O. Hall, K. Stewart, N. A. Dosselman, L. J. El Tecle, N. E. McDonald, S. R. Bagley, C. A. Wingfield, S. A. J Am Geriatr Soc 2021

Aged
Delirium/epidemiology/*prevention & control
Elective Surgical Procedures/*adverse effects
Female
Geriatric Assessment
Health Plan Implementation
Humans
Incidence
Male
Patient Care Team
Perioperative Care/*methods
Postoperative Cognitive Complications/epidemiology/*prevention & control
Program Evaluation
Retrospective Studies
Spine/*surgery
*deformity
*delirium
*geriatric
*interdisciplinary | surgery
*prevention
*spine

Postoperative delirium mediates 180-day mortality in orthopaedic trauma patients Pedemonte, J. C. Sun, H. Franco-Garcia, E. Zhou, C. Heng, M. Quraishi, S. A. Westover, B. Akeju, O. Br J Anaesth 2021

Aged
Aged, 80 and over
Emergence Delirium/diagnosis/*mortality
Female
Frail Elderly
Frailty/diagnosis/*mortality/*surgery
Geriatric Assessment/methods
Humans
Male
Mortality/trends
Orthopedic Procedures/*mortality/trends
Retrospective Studies
Time Factors
Wounds and Injuries/diagnosis/*mortality/*surgery
*frailty
*mortality
*orthopaedic trauma
*perioperative
*postoperative delirium

Evaluating Pain, Opioids, and Delirium in Critically Ill Older Adults Pavone, K. J. Jablonski, J. Cacchione, P. Z. Polomano, R. C. Compton, P. Clin Nurs Res 2021

Aged
*Analgesics, Opioid/adverse effects
Critical Illness
*Delirium
Humans
Intensive Care Units
Pain/drug therapy
Prospective Studies
Retrospective Studies
*sicu
*critical care
*elderly
*older adult
*opioid
*pain

Optimizing the Recognition and Treatment of In-Hospital Stroke: Evaluation of the 2CAN Score Parrino, C. R. Noles, A. Lalla, R. Mehndiratta, P. Phipps, M. Cronin, C. Cole, J. Wozniak, M. Yarbrough, K. Chaturvedi, S. J Stroke Cerebrovasc Dis 2021

Aged
Clinical Decision-Making
*Decision Support Techniques
Diagnosis, Differential
Female
Fibrinolytic Agents/*administration & dosage
Functional Status
Humans
Inpatients
Male
Middle Aged
Predictive Value of Tests
Reproducibility of Results
Retrospective Studies
Risk Assessment
Risk Factors
Stroke/*diagnosis/etiology/physiopathology/*therapy
*Thrombectomy
*Thrombolytic Therapy
Tissue Plasminogen Activator/*administration & dosage
Treatment Outcome
2CAN score
Cerebrovascular disorders
Inpatient stroke
Nihss
Quality improvement
Validation study

Cohort Analysis of the Association of Delirium Severity with Cerebrospinal Fluid Amyloid-Tau-Neurodegeneration Pathologies Parker, M. White, M. Casey, C. Kunkel, D. Bo, A. Blennow, K. Zetterberg, H. Pearce, R. A. Lennertz, R. Sanders, R. D. J Gerontol A Biol Sci Med Sci 2021

Biology of aging, Biomarkers, Dementia

The Delirium Observation Screening Scale: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy Park, J. Jeong, E. Lee, J Clin Nurs Res 2021

*Delirium/diagnosis
*Diagnostic Tests, Routine
Humans
Mass Screening
Sensitivity and Specificity
*delirium
*diagnostic test accuracy
*meta-analysis
*screening test
*systematic review

Higher neutrophil-to-lymphocyte ratio, mean platelet volume, and platelet distribution width are associated with postoperative delirium in patients undergoing esophagectomy: a retrospective observational study Oyama, T. Kinoshita, H. Takekawa, D. Saito, J. Kushikata, T. Hirota, K. J Anesth 2021

Esophagectomy
Mean platelet volume
Neutrophil-to-lymphocyte ratio
Platelet distribution width
Postoperative delirium

The predictive value of the 'VMS frail older patients' for adverse outcomes in geriatric inpatients Oud, F. M. M. Wolzak, N. K. Spies, P. E. Zaag-Loonen, H. J. V. van Munster, B. C. Arch Gerontol Geriatr 2021

Aged
Aged, 80 and over
*Frail Elderly
Geriatric Assessment
Humans
Inpatients
Male
*Malnutrition/diagnosis/epidemiology
Retrospective Studies
*Institutionalization
*Mortality
*Prediction
*Readmission
*Vulnerable

Impact of ABCDE Bundle Implementation in the Intensive Care Unit on Specific Patient Costs Otusanya, O. T. Hsieh, S. J. Gong, M. N. Gershengorn, H. B. J Intensive Care Med 2021

cost and cost analysis
critical care
early ambulation
intensive care units
laboratories
radiology

Use of Suvorexant and Antipsychotics in the Treatment of Delirium After Infectious Diseases: A Retrospective Study Okino, K. Yamada, H. Tomioka, H. Nozaki, S. Iwanami, A. Inamoto, A. J Clin Psychopharmacol 2021

Antipsychotics, Suvorexant, Delirium, Infectious Disease, C-reactive protein, White blood cell count

The assessment of risk factors for postoperative delirium using cubic spline curves in gastroenterological surgery Okawa, Y. Tanaka, K. Nakanishi, Y. Asano, T. Noji, T. Ebihara, Y. Kurashima, Y. Nakamura, T. Murakami, S. Tsuchikawa, T. Okamura, K. Shichinohe, T. Hirano, S. Surg Today 2021

Cubic spline curve
Gastroenterological surgery
Postoperative delirium
Risk factor

Delirium and Long-Term Outcomes among Survivors of Extracorporeal Membrane Oxygenation Therapy: A Nationwide Cohort Study in South Korea Oh, T. K. Park, H. Y. Song, I. A. J Intensive Care Med 2021

Critical Care
Ecmo
ICU outcomes
intensive care unit
mortality

The Impact of Earplugs and Eye Masks on Sleep Quality in Surgical ICU Patients at Risk for Frequent Awakenings Obanor, O. O. McBroom, M. M. Elia, J. M. Ahmed, F. Sasaki, J. D. Murphy, K. M. Chalk, S. Menard, G. A. Pratt, N. V. Venkatachalam, A. M. Romito, B. T. Crit Care Med 2021

Adult
Delirium/diagnosis/epidemiology
Ear Protective Devices/*standards/statistics & numerical data
Eye Protective Devices/*standards/statistics & numerical data
Female
Hospitalization/statistics & numerical data
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Middle Aged
Noise/adverse effects
Prospective Studies
Simplified Acute Physiology Score
Sleep Wake Disorders/epidemiology/*prevention & control
Surveys and Questionnaires
Texas/epidemiology
interest.

Interventions to support recovery following an episode of delirium: A realist synthesis O'Rourke, G. Parker, D. Anderson, R. Morgan-Trimmer, S. Allan, L Aging Ment Health 2021

Aged
*Cognitive Behavioral Therapy
*Delirium/therapy
Humans
*Delirium
*older adults
*realist review
*rehabilitation

Preoperative inflammatory mediators and postoperative delirium: systematic review and meta-analysis Noah, A. M. Almghairbi, D. Evley, R. Moppett, I. K. Br J Anaesth 2021

Aged
Aged, 80 and over
Biomarkers/blood
Delirium/blood/diagnosis/*etiology
Female
Humans
Inflammation Mediators/*blood
Interleukin-6/blood
Male
Middle Aged
Neopterin/blood
Preoperative Care
Risk Assessment
Risk Factors
Surgical Procedures, Operative/*adverse effects
Treatment Outcome
Up-Regulation
cytokines
delirium
inflammatory markers
neuroinflammation
older people
postoperative delirium

Development of an algorithm for assessing fall risk in a Japanese inpatient population Nakanishi, T. Ikeda, T. Nakamura, T. Yamanouchi, Y. Chikamoto, A. Usuku, K. Sci Rep 2021

Disease prevention, Geriatrics, Public health

Relationship among melatonin, postoperative delirium, and postoperative cognitive dysfunction Mu, S. Wu, Y. Wu, A. Ann Palliat Med 2021

*Cognition Disorders
*Delirium
Humans
Incidence
*Melatonin
*Postoperative Cognitive Complications
6-sulfatoxymelatonin (6-SMT)
Melatonin
creatinine
postoperative cognitive dysfunction (POCD)
postoperative delirium (POD)

Hospital complications among older adults: Better processes could reduce the risk of delirium Moura Junior, V. Westover, M. B. Li, F. Kimchi, E. Kennedy, M. Benson, N. M. Moura, L. M. Hsu, J. Health Serv Manage Res 2021

access/demand/utilization of services
aging
clinical practice patterns
geriatrics
health care organizations and systems
hospitals
integrated delivery systems
mental health
quality of care/patient safety

Precipitated Withdrawal, Delirium, and Cerebellar Stroke: The Pharmacology of Buprenorphine Induction in Non-pharmaceutical Fentanyl and the Neuropsychiatric Manifestations of Cerebellar Stroke Montalvo, C. von Horn, A. Lane, C. E. Weinstein, Z. M. Sharma, M. Suzuki, J. Harv Rev Psychiatry 2021
The effect of foot massage on the level of consciousness and delirium of intensive care patients: A randomized single-blind controlled trial Momeni, M. Arab, M. Dehghan, M. Ahmadinejad, M. J Bodyw Mov Ther 2021

*Consciousness
Critical Care
*Delirium
Humans
Massage
Single-Blind Method
Delirium
Intensive care unit
Level of consciousness
Massage
competing financial interests or personal relationships that could have appeared to
influence the work reported in this paper.

Intravenous patient-controlled analgesia does not increase the risk of postoperative delirium compared to patient-controlled epidural analgesia: a propensity score-matched retrospective cohort study Miyoshi, H. Nakamura, R. Noda, Y. Yokomi, H. Kamiya, S. Morio, A. Watanabe, T. Narasaki, S. Toyota, Y. Saeki, N. Hamada, H. Tsutsumi, Y. M. Ann Palliat Med 2021

Patient-controlled analgesia (PCA)
epidural analgesia
opioid
postoperative delirium (POD)

Standardized Semistructured Psychosocial Evaluation Before Stem Cell Transplantation Predicts Delirium After Transplant Mishkin, A. D. Schmajuk, M. Reshef, R. Lopez-Pintado, S. Mapara, M. Y. Shapiro, P. A. J Acad Consult Liaison Psychiatry 2021

*cancer (PSY0140)
*consultation-liaison psychiatry (PSY0230)
*psycho-oncology (PSY0550)
*transplantation (PSY0710)

Pattern of Brain Injury in Patients With Thrombotic Thrombocytopenic Purpura in the Precaplacizumab Era Mirouse, A. Legriel, S. Dumas, G. Labro, G. Veyradier, A. Zafrani, L. Valade, S. Hourmant, Y. Boutboul, D. Darmon, M. Coppo, P. Mariotte, E. Azoulay, E. Crit Care Med 2021

Adult
Brain Injuries/epidemiology/*etiology
Cohort Studies
Female
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Middle Aged
Prognosis
Prospective Studies
Purpura, Thrombotic Thrombocytopenic/*complications/epidemiology

Postoperative delirium is a risk factor for complications and poor outcome after total hip and knee arthroplasty Meyer, M. Götz, J. Parik, L. Renkawitz, T. Grifka, J. Maderbacher, G. Kappenschneider, T. Weber, M. Acta Orthop 2021

Geriatrics, Surgery, Postoperative delirium, Elective joint replacement

Why should you stay one night? Prospective observational study of enhanced recovery in elderly patients Melegari, G. Albertini, G. Romani, A. Malaguti, S. Traccitto, F. Giuliani, E. Cavallini, G. M. Bertellini, E. Barbieri, A. Aging Clin Exp Res 2021

Aged
*Delirium
Humans
Incidence
Postoperative Complications
Prospective Studies
Delirium
Elderly patients
Perioperative management
Surgery

Inhaled isoflurane via the anaesthetic conserving device versus propofol for sedation of invasively ventilated patients in intensive care units in Germany and Slovenia: an open-label, phase 3, randomised controlled, non-inferiority trial Meiser, A. Volk, T. Wallenborn, J. Guenther, U. Becher, T. Bracht, H. Schwarzkopf, K. Knafelj, R. Faltlhauser, A. Thal, S. C. Soukup, J. Kellner, P. Drüner, M. Vogelsang, H. Bellgardt, M. Sackey, P. Lancet Respir Med 2021

Isoflurane, ICU, Propofol, Invasive ventilation, RASS

Perioperative Considerations for Patients with a Known Diagnosis of Dementia McSwain, J. R. Sirianni, J. M. Wilson, S. H. Adv Anesth 2021

Alzheimer’s dementia
Dementia
Intraoperative considerations
Multidisciplinary care
Perioperative considerations
Postoperative considerations
Postoperative delirium
Preoperative evaluation
interest to declare with regards to this article. There is no external funding to
report. All authors fully participated in the research, writing, and editing of this
article.

The relationship between frailty and delirium: insights from the 2017 Delirium Day study Mazzola, P. Tassistro, E. Di Santo, S. Rossi, E. Andreano, A. Valsecchi, M. G. Cherubini, A. Marengoni, A. Mossello, E. Bo, M. Inzitari, M. Di Bari, M. Udina, C. Latronico, N. Paolillo, C. Morandi, A. Bellelli, G. Age Ageing 2021

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology
*Frailty/diagnosis
Geriatric Assessment
Humans
Prospective Studies
Risk Factors
*Delirium Day
*delirium
*frailty
*mortality
*older people

Absence of Longer Reorientation Times in Patients Undergoing Electroconvulsive Therapy and Concomitant Treatment with Lithium Martins-Ascencao, R. Rodrigues-Silva, N. Trovão, N. Clin Psychopharmacol Neurosci 2021

Cognitive dysfunction
Confusion
Electroconvulsive therapy
Lithium
Orientation

Period-Prevalence and Risk Factors for Delirium in a Tertiary Referral ICU: A prospective cohort study Martinez, F. E. Ho, V. W. Brogan, G. Pickering, C. Leung, G. Parrey, J. Charlton, A. Acute Med 2021

Adult
*Delirium/epidemiology/etiology
Humans
Intensive Care Units
Prevalence
Prospective Studies
Referral and Consultation
Risk Factors

Cross-Cultural Adaptation and Validation of the Italian Version of the Observational Scale of Level of Arousal Martella, L. A. Carmisciano, L. Giannotti, C. Signori, A. Pontremoli, R. Giusti, M. Gualco, E. Beccati, V. Marengoni, A. Nencioni, A. Monacelli, F. J Am Med Dir Assoc 2021

Aged
Arousal
*Cross-Cultural Comparison
*Delirium/diagnosis
Humans
Italy
Longitudinal Studies
Middle Aged
Reproducibility of Results
*Delirium
*OSLA validation.
*level of consciousness
*longitudinal assessment
*older adults

Prevalence and management of delirium in community dwelling older people with dementia referred to a memory clinic Manni, B. Federzoni, L. Zucchi, P. Mussi, C. Inzitari, M. Carda, C. A. Fabbo, A. Morandi, A. Aging Clin Exp Res 2021

Aged
*Delirium/diagnosis/epidemiology/therapy
*Dementia/epidemiology
Hospitalization
Humans
Independent Living
Prevalence
Retrospective Studies
Delirium
Dementia
Home care

Impact of a Real-Time, Pharmacist-Led, Intensive Care Unit-Based Feedback Intervention on Analgesia and Sedation Quality Among Mechanically Ventilated Patients Mancheril, B. Kram, B. Schultheis, J. Kram, S. Trammel, M. Liu, B. Jordan, W. Cox, C. E. J Nurs Care Qual 2021

*Analgesia
*Delirium
Feedback
Humans
Hypnotics and Sedatives
Intensive Care Units
Pain
Pharmacists
Prospective Studies
Respiration, Artificial

A New ICU Delirium Prevention Bundle to Reduce the Incidence of Delirium: A Randomized Parallel Group Trial Malik, A. K. Baidya, D. K. Anand, R. K. Subramaniam, R. Indian J Crit Care Med 2021

Delirium
Intensive care unit
Mechanical ventilation

Risk factors associated with the development of delirium in general ICU patients. A prospective observational study Lobo-Valbuena, B. Gordo, F. Abella, A. Garcia-Manzanedo, S. Garcia-Arias, M. M. Torrejón, I. Varillas-Delgado, D. Molina, R. PLoS One 2021

Delirium, ICU Delirium, CAM-ICU, Clinical Frailty Scale, Length of stay, Readmission rate

Incidence, Predictors and Outcomes of Delirium in Complicated Type B Aortic Dissection Patients After Thoracic Endovascular Aortic Repai Liu, J. Yang, F. Luo, S. Li, C. Liu, W. Liu, Y. Huang, W. Xie, E. Chen, L. Su, S. Yang, X. Geng, Q. Luo, J. Clin Interv Aging 2021

*Aneurysm, Dissecting/surgery
*Aortic Aneurysm, Thoracic/surgery
*Blood Vessel Prosthesis Implantation
Cross-Sectional Studies
*Delirium/epidemiology
*Endovascular Procedures
Humans
Incidence
Male
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
hybrid procedure
outcomes
postoperative delirium
predictors
thoracic endovascular aortic repair
type B aortic dissection

Dynamic Delirium Severity Trajectories and Their Association With 2-Year Healthcare Utilization and Mortality Outcomes Lindroth, H. Mohanty, S. Ortiz, D. Gao, S. Perkins, A. J. Khan, S. H. Boustani, M. A. Khan, B. A. Crit Care Explor 2021

delirium
delirium severity
healthcare utilization
mortality
trajectories

Intraoperative Oxygen Concentration and Postoperative Delirium After Laparoscopic Gastric and Colorectal Malignancies Surgery: A Randomized, Double-Blind, Controlled Trial Lin, X. Wang, P. Liu, D. W. Guo, Y. W. Xie, C. H. Wang, B. Dong, R. Sun, L. X. Wang, M. S. Bi, Y. L. Clin Interv Aging 2021

Aged
Aged, 80 and over
Colorectal Neoplasms/surgery
Delirium/*blood/etiology
Digestive System Surgical Procedures/adverse effects/*methods
Double-Blind Method
Humans
Laparoscopy/adverse effects
Male
Oxygen/*blood
Postoperative Complications/*blood/etiology
Postoperative Period
intraoperative oxygen concentration
malignancy
postoperative delirium
conflicts of interest to report.

Incidence of delirium following hospitalization of elderly people with fractures: risk factors and mortality Lima, B. R. Nunes, B. K. G. Guimarães, Lcdc Almeida, L. F. Pagotto, V. Rev Esc Enferm USP 2021

Aged
Aged, 80 and over
*Delirium/epidemiology/etiology
Hospitalization
Humans
Incidence
Male
Prospective Studies
Risk Factors

Regional Nerve Block Decreases the Incidence of Postoperative Delirium in Elderly Hip Fracture Lim, E. J. Koh, W. U. Kim, H. Kim, H. J. Shon, H. C. Kim, J. W. J Clin Med 2021

delirium
hip fracture
nerve block
opioids
pain

Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials Li, X. Wang, Y. Liu, J. Xiong, Y. Chen, S. Han, J. Xie, W. Wu, Q. Medicine (Baltimore) 2021

Delirium/*prevention & control
Humans
Postoperative Complications/prevention & control
Preoperative Period
Randomized Controlled Trials as Topic
Research Design

Developing a machine learning model to identify delirium risk in geriatric internal medicine inpatients Li, Q. Zhao, Y. Chen, Y. Yue, J. Xiong, Y. Eur Geriatr Med 2021

Delirium
Elderly
Internal medicine
Machine learning
Predictive model

Development and validation of a risk score for predicting postoperative delirium after major abdominal surgery by incorporating preoperative risk factors and surgical Apgar score Li, G. H. Zhao, L. Lu, Y. Wang, W. Ma, T. Zhang, Y. X. Zhang, H. J Clin Anesth 2021

Bootstrapping
Elastic net regression
Major open abdominal surgery
Postoperative delirium prediction
Surgical Apgar score

Non-Pharmacological Nursing Interventions for Prevention and Treatment of Delirium in Hospitalized Adult Patients: Systematic Review of Randomized Controlled Trials Lee, Y. Lee, J. Kim, J. Jung, Y. Int J Environ Res Public Health 2021

Adult
Cognition
*Delirium/prevention & control
Ear Protective Devices
Humans
Patients
Randomized Controlled Trials as Topic
*delirium
*hospitalization
*non-pharmacologic intervention
*nursing intervention
*systematic review

Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit Lee, H. J. Bae, E. Lee, H. Y. Lee, S. M. Lee, J. Acute Crit Care 2021

delirium
intensive care unit
light

Knowledge, barriers, and training needs of nurses working in delirium care Lee, G. Roh, Y. S Nurs Crit Care 2021

barrier
delirium
knowledge
nurse
performance

Causes and Predictors of 30-Day Readmission in Elderly Patients With Delirium Lau, H. L. Patel, S. D. Garg, N. Neurol Clin Pract 2021

Readmission rate, Delirium, Hospitalization, Length of stay, Post discharge care

Comparison of Antipsychotics for the Treatment of Patients With Delirium and QTc Interval Prolongation: A Clinical Decision Analysis Kurisu, K. Yoshiuchi, K. Front Psychiatry 2021

QTc prolongation
antipsychotics
clinical decision analysis
delirium
quetiapine
or financial relationships that could be construed as a potential conflict of
interest.

The Polish Version of the Nursing Delirium Screening Scale (NuDESC PL)-Experience of Using in Nursing Practice in Cardiac Surgery Intensive Care Unit Krupa, S. Dorota, O. Friganovic, A. Mędrzycka-Dąbrowska, W. Jurek, K. Int J Environ Res Public Health 2021

Cardiac Surgical Procedures/adverse effects
*Delirium/diagnosis
Humans
Intensive Care Units
*Nurses
Poland
*delirium
*disorientation
*nursing delirium screening scale
*screening

Associations of delirium with urinary tract infections and asymptomatic bacteriuria in adults aged 65 and older: A systematic review and meta-analysis Krinitski, D. Kasina, R. Klöppel, S. Lenouvel, E. J Am Geriatr Soc 2021

asymptomatic bacteriuria
delirium
urinary tract infection

Prevalence and Factors Affecting Postoperative Delirium in a Neurosurgical Intensive Care Unit Kose, G. Şirin, K. Inel, M. B. Mertoglu, S. Aksakal, R. Kurucu, Ş J Neurosci Nurs 2021

Cross-Sectional Studies
*Delirium
Humans
*Intensive Care Units
*Neurosurgery
Postoperative Complications
Prevalence
Prospective Studies
Risk Factors

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Kong, S. Wang, J. Xu, H. Wang, K. Oncotarget 2021

hypertension
oral tumor surgery
postoperative delirium
the elderly
respect to the research, authorship and/or publication of this article.

Perioperative Electroencephalogram Spectral Dynamics Related to Postoperative Delirium in Older Patients Koch, S. Windmann, V. Chakravarty, S. Kruppa, J. Yürek, F. Brown, E. N. Winterer, G. Spies, C. Anesth Analg 2021

Electroencephalography, Postoperative delirium, Surgery, Spectral edge frequency

Is dislocation following total hip arthroplasty caused while suffering from delirium? Kobayashi, T. Morimoto, T. Sonohata, M. Mawatari, M. Nagoya J Med Sci 2021

dislocation
postoperative delirium
total hip arthroplasty

Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study Kinoshita, H. Saito, J. Takekawa, D. Ohyama, T. Kushikata, T. Hirota, K. PLoS One 2021

Postoperative delirium, ICU delirium, Neutrophil-lymphocyte ratio, Surgery, Length of Stay

Delirium risk of histamine-2 receptor antagonists and proton pump inhibitors: A study based on the adverse drug event reporting database in Japan Kikkawa, N. Sogawa, R. Monji, A. Sumi, S. Murakawa-Hirachi, T. Kubo, T. Eguchi, Y. Miyamoto, Y. Kamo, M. Tobita, S. Yukawa, M. Uchida, R. Egoshi, M. Shimanoe, C. Gen Hosp Psychiatry 2021

Delirium
Histamine-2 receptor antagonist
Proton pump inhibitor

Delirium in neurosurgery: a systematic review and meta-analysis Kappen, P. R. Kakar, E. Dirven, C. M. F. van der Jagt, M. Klimek, M. Osse, R. J. Vincent, Apje Neurosurg Rev 2021

Delirium
Incidence rates
Neurosurgery
Screening tools

Risk factors for postoperative delirium and subsyndromal delirium in older patients in the surgical ward: A prospective observational study Kanno, M. Doi, M. Kubota, K. Kanoya, Y. PLoS One 2021

Postoperative delirium, Subsyndromal delirium, Surgery, CAM

Diagnostic accuracy and clinical applicability of the Swedish version of the 4AT assessment test for delirium detection, in a mixed patient population and setting Johansson, Y. A. Tsevis, T. Nasic, S. Gillsjö, C. Johansson, L. Bogdanovic, N. Kenne Sarenmalm, E BMC Geriatr 2021

Aged
*Delirium/diagnosis/epidemiology
Geriatric Assessment
Humans
Reproducibility of Results
Sensitivity and Specificity
Sweden/epidemiology
*4at
*Applicability
*Delirium
*Diagnostic accuracy
*Qualitative content analysis
*Validation study

In-Hospital Delirium as a Prognostic Factor for New Cognitive Disorder in a 1-Year Post-Hip Fracture Follow-Up Jaatinen, R. Luukkaala, T. Hongisto, M. T. Helminen, H. Nuotio, M. S. Dement Geriatr Cogn Disord 2021

Cognition
Delirium
Hip fracture
Outcome
Prognosis

Italian version of the short 10/66 dementia diagnostic schedule: a validation study Ibnidris, A. Piumatti, G. Carlevaro, F. Fadda, M. Magno, F. Magistro, D. Albanese, E. BMJ Open 2021

Aged
Cross-Sectional Studies
*Dementia/diagnosis
Female
Humans
Italy/epidemiology
Male
Middle Aged
ROC Curve
Switzerland
*delirium & cognitive disorders
*dementia
*old age psychiatry

A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study Hur, S. Ko, R. E. Yoo, J. Ha, J. Cha, W. C. Chung, C. R. JMIR Med Inform 2021

clinical prediction
delirium
electronic health record
intensive care unit
machine learning

The effect of evidence-based cluster nursing intervention on the incidences of delirium and the prognoses of ICU patients Huang, S. Xu, J. Du, Y. Wang, Y. Wei, H. Wei, G. Hu, M. Am J Transl Res 2021

Evidence-based medicine
Icu
cluster nursing intervention
delirium
prognosis

Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled tria Hong, H. Zhang, D. Z. Li, M. Wang, G. Zhu, S. N. Zhang, Y. Wang, D. X. Sessler, D. I. BMC Anesthesiol 2021

Delirium
Dexmedetomidine
Elderly
Orthopedic Procedures
Postoperative Period

Effects of a simulation-based education programme on delirium care for critical care nurses: A randomized controlled trial Ho, M. H. Yu, L. F. Lin, P. H. Chang, H. R. Traynor, V. Huang, W. C. Montayre, J. Chen, K. H. J Adv Nurs 2021

Clinical Competence
Critical Care
*Delirium
Humans
*Nurses
Taiwan
competence
confidence
delirium
knowledge
nurses
simulation

Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium Ho, M. H. Nealon, J. Igwe, E. Traynor, V. Chang, H. R. Chen, K. H. Montayre, J. Worldviews Evid Based Nurs 2021

Aged
Checklist
Cohort Studies
*Delirium/epidemiology/etiology
Humans
Incidence
Risk Factors
data pooling
epidemiology
geriatrics
gerontology
healthcare outcomes
meta-analysis
nervous system diseases
neurology
patient outcomes

Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N. Am J Geriatr Psychiatry 2021
Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients Heinrich, M. Sieg, M. Kruppa, J. Nürnberg, P. Schreier, P. H. Heilmann-Heimbach, S. Hoffmann, P. Nöthen, M. M. Janke, J. Pischon, T. Slooter, A. J. C. Winterer, G. Spies, C. D. BMC Med Genomics 2021

Chrm2
Chrm4
Genome-wide association study
Neurocognitive disorder

Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury Hansen, P. M. Lauridsen, J. T. Frandsen, N. S. Dan Med J 2021

*Brain Injuries
*Delirium/etiology
Glasgow Coma Scale
Humans
*Neurological Rehabilitation
*Stroke

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis Han, Q. Y. C. Rodrigues, N. G. Klainin-Yobas, P. Haugan, G. Wu, X. J Am Med Dir Assoc 2021

Dementia
delirium
delirium superimposed on dementia
meta-analysis
older adults
prevalence
risk factors

Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study Guan, H. L. Liu, H. Hu, X. Y. Abdul, M. Dai, M. S. Gao, X. Chen, X. F. Zhou, Y. Sun, X. Zhou, J. Li, X. Zhao, Q. Zhang, Q. Q. Wang, J. Han, Y. Cao, J. L. CNS Neurosci Ther 2021

delirium
elderly patient
the blood-brain barrier
urinary albumin creatinine ratio

Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery Goldstein, D. P. Blasco, M. de Almeida, J. Su, J. Xu, W. Cohen, M. Sklar, M. Alibhai, S Otolaryngol Head Neck Surg 2021

clock draw test
cognitive impairment
delirium
head neck surgery
older patients

What prompts patients to present with delirium? Gibb, K. Krywonos, A. Shah, R. Jha, A. Davis, D. Eur Geriatr Med 2021

Adult
Aged, 80 and over
Caregivers
*Delirium/diagnosis
Hospitalization
Humans
Surveys and Questionnaires
*Awareness
*Delirium
*Recognition
*Response

Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit Fu, Z. Xu, Q. Zhang, C. Bai, H. Chen, X. Zhang, Y. Luo, W. Lin, G. Int J Gen Med 2021

acute Stanford type A aortic dissection
intensive care unit
major surgery
post-operative delirium
systolic blood pressure

Postoperative Delirium in Patients After Brain Tumor Surgery French, J. Weber, T. Ge, B. Litofsky, N. S. World Neurosurg 2021

Confusion assessment method
Delirium
Recognition
Tumor resection

Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis Franks, Z. M. Alcock, J. A. Lam, T. Haines, K. J. Arora, N. Ramanan, M. Ann Am Thorac Soc 2021

Adult
*Critical Illness
Humans
Intensive Care Units
Randomized Controlled Trials as Topic
Restraint, Physical
*Stress Disorders, Post-Traumatic/etiology/prevention & control
Survivors
*critical care
*delirium
*physical restraint
*post-traumatic stress disorder
*post–intensive care syndrome

Long-Term Outcomes in ICU Patients with Delirium: A Population-based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

Adolescent
Adult
Aged
Aged, 80 and over
Alberta/epidemiology
Critical Illness
Delirium/*mortality
Facilities and Services Utilization/*statistics & numerical data
Female
Follow-Up Studies
Humans
*Intensive Care Units
Male
Middle Aged
Patient Discharge
Prognosis
Propensity Score
Retrospective Studies
Survival Analysis
Young Adult
*critical care
*delirium
*mortality

The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial Fazlollah, A. Babatabar Darzi, H. Heidaranlu, E. Moradian, S. T. Complement Ther Med 2021

*Cardiac Surgical Procedures/adverse effects
*Delirium/etiology/therapy
Humans
*Massage
*Musculoskeletal Manipulations
Sleep
*Sleep Wake Disorders/etiology/therapy
Cardiac surgical procedure
Delirium
Massage
Pain measurement
Sleep hygiene

A delirium prevalence audit and a pre and post evaluation of an interprofessional education intervention to increase staff knowledge about delirium in older adults Ewens, B. Seaman, K. Whitehead, L. Towell-Barnard, A. Young, M. BMC Nurs 2021

Delirium
Delirium assessment
Delirium knowledge
Interprofessional education, quality improvement
Symptom recognition

Anaesthetic depth and delirium after major surgery: a randomised clinical trial Evered, L. A. Chan, M. T. V. Han, R. Chu, M. H. M. Cheng, B. P. Scott, D. A. Pryor, K. O. Sessler, D. I. Veselis, R. Frampton, C. Sumner, M. Ayeni, A. Myles, P. S. Campbell, D. Leslie, K. Short, T. G. Br J Anaesth 2021

anaesthesia
bispectral index
cognitive dysfunction
delirium
electroencephalography
postoperative delirium

Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients Esmaeeli, S. Franco-Garcia, E. Akeju, O. Heng, M. Zhou, C. Azocar, R. J. Quraishi, S. A. Aging Clin Exp Res 2021

Cognition
Delirium
Frailty
Postoperative delirium
Trauma

Prevention of postoperative delirium after cardiovascular surgery: A team-based approach Enomoto, K. Kosaka, S. Kimura, T. Matsubara, M. Kitada, Y. Mieno, M. Okamura, H. J Thorac Cardiovasc Surg 2021

Delirium Team Approach program
benzodiazepine
cardiovascular surgery
postoperative delirium

Serum Levels of S100β, Neuron-Specific Enolase, Glial Fibrillary Acidic Protein in Kidney Transplant Recipients and Donors: A Prospective Cohort Study Dinc, B. Yılmaz, V. T. Aslan, M. Aycan, I. O. Kiraz, N. Kisaoglu, A. Dandin, O. Hadimioglu, N. Ertug, Z. Transplant Proc 2021

Nephrectomy, Kidney transplant, Neuromarkers, Postoperative delirium

Delirium and Its Pharmacological Causes in Older People, Part 1 DeMaagd, G. A. DeMaagd, D. R. Philip, A. Coalter, C. F. Sr Care Pharm 2021

Aged
*Delirium/chemically induced/diagnosis/epidemiology
Human

Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes Delgado, J. Jones, L. Bradley, M. C. Allan, L. M. Ballard, C. Clare, L. Fortinsky, R. H. Hughes, C. M. Melzer, D. Age Ageing 2021

Aged
Aged, 80 and over
*Dementia/diagnosis/drug therapy/epidemiology
England/epidemiology
Humans
*Inappropriate Prescribing
Incidence
Multimorbidity
Outcome Assessment, Health Care
Potentially Inappropriate Medication List
Retrospective Studies
*Alzheimer’s
*Beer’s
*Parkinson’s
*delirium
*hospitalisation
*misprescribing
*mortality
*older people
*vascular dementia

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients Delaney, L. J. Litton, E. Van Haren, F. Crit Care Nurs Clin North Am 2021

Critical Care
*Delirium/epidemiology
Humans
Intensive Care Units
Sleep
*Sleep Wake Disorders/epidemiology
Delirium
Intensive care
Light
Noise
Sleep disturbance

Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer De León, L. E. Rochefort, M. M. Bravo-Iñiguez, C. E. Fox, S. W. Tarascio, J. N. Cardin, K. DuMontier, C. Frain, L. N. Jaklitsch, M. T. J Geriatr Oncol 2021

Aged
Humans
Length of Stay
*Lung Neoplasms/surgery
Morbidity
Postoperative Complications/epidemiology
*Quality Improvement
Retrospective Studies
Thoracic Surgery, Video-Assisted
Thoracotomy
*Lobectomy
*Minimally invasive surgery
*Morbidity
*Older adult
*Oncology outcomes
*Postoperative outcomes
*Thoracic surgery

Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study de Araujo, C. Z. S. de Araújo, L. Z. S. Nassar Junior, A. P. Palliat Support Care 2021

Cancer
Cancer care facilities
Deep sedation
End-of-life care
Palliative care

Development and Implementation of a Multicomponent Protocol to Promote Sleep and Reduce Delirium in a Medical Intensive Care Unit Darby, A. Northam, K. Austin, C. A. Chang, L. Campbell-Bright, S Ann Pharmacother 2021

critical care
mechanical ventilators
quality assurance
sedatives
sleep disorders

Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors Damoiseaux-Volman, B. A. van der Velde, N. Ruige, S. G. Romijn, J. A. Abu-Hanna, A. Medlock, S. JMIR Med Inform 2021

aged
clinical decision support systems
geriatrics
hospital
quality of care

Sevoflurane-Remifentanil Versus Propofol-Remifentanil Anesthesia During Noncardiac Surgery for Patients with Coronary Artery Disease - A Prospective Study Between 2016 and 2017 at a Single Center Dai, Z. Lin, M. Li, Y. Gao, W. Wang, P. Lin, J. Wan, Z. Jiang, Y. Med Sci Monit 2021

Acute Coronary Syndrome, Coronary Artery Disease, Propofol