Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Restraint use in the acute-care hospital setting: A cross-sectional multi-centre study
Authors
Thomann, S. Zwakhalen, S. Richter, D. Bauer, S. Hahn, S.
Year
2021
Journal
Int J Nurs Stud
Abstract

BACKGROUND: Restraints are likely to negatively affect patients’ health and therefore a reduction in their usage is recommended for all health-care settings. To date, research on restrictive practices has concentrated on mental health and long-term care settings. In the acute-care hospital setting few studies have been published and these studies mainly focus on physical/mechanical restraints in specific subpopulations and/or on intensive care units. However, to ensure restraints are used as little as possible in the acute-care hospital setting, it seems important to investigate more comprehensively the use of restraints, to include all types of restraints irrespective of ward type or subpopulations and to identify factors associated with restraint use. OBJECTIVE: The aim of this study was to investigate restraint use regardless of ward type in the acute-care hospital setting, including restraint type, reasons for restraint use, process indicators when using restraints and restraint use-associated patient characteristics. METHODS: Using a cross-sectional multi-centre design, data were collected by means of an annual international prevalence measurement in acute-care hospitals in Switzerland and Austria. All hospitalised patients aged 18+ who gave informed consent were included. Data were collected at three measurement points between 2016 and 2018. Descriptive and multivariate logistic regression analyses were performed. RESULTS: A total of 29,477 patients hospitalised in 140 hospitals were included in this study. The prevalence rate for the use of at least one restraint over a 30-day period was 8.7% (n = 2577), with mechanical restraints representing the highest proportion of restraint type used (55.0%, n = 1417). The main reason for restraint use was fall prevention (43.8%, n = 1129), followed by confusion or delirious behaviour (20.4%, n = 525). In 64.3% of the cases (n = 1657), restraint use was documented in the patient file. Regular evaluation occurred in 42.9% of the cases (n = 1105). Care dependency had the strongest association with restraint use (odds ratio [OR] 25.00, 95% confidence interval [CI] 21.01-29.78 for completely dependant patients in comparison to completely independent patients), followed by mental and behavioural disorders (OR 2.36, 95% CI 2.15-2.59). CONCLUSIONS: Restraints are often utilised in hospitals in complex care situations such as with patients at risk of falling or with delirium. When using restraints the consideration of processes like documentation and evaluation shows great potential for improvement. Standardisation of these processes and education of the interprofessional team could be beneficial for raising awareness and for the sustainable reduction of restraint use. Tweetable abstract: In hospitals restraints are often used in complex care situations. However, their use seems to be insufficiently documented and evaluated.

PMID

33217663

Keywords

Cross-Sectional Studies
*Hospitals
Humans
Long-Term Care
*Restraint, Physical
Switzerland
Health-care outcome and process assessment
Hospitals
Prevalence
Restraints
Risk factors

Page(s)
Issue

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Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
The effect of foot massage on the level of consciousness and delirium of intensive care patients: A randomized single-blind controlled trial Momeni, M. Arab, M. Dehghan, M. Ahmadinejad, M. J Bodyw Mov Ther 2021

*Consciousness
Critical Care
*Delirium
Humans
Massage
Single-Blind Method
Delirium
Intensive care unit
Level of consciousness
Massage
competing financial interests or personal relationships that could have appeared to
influence the work reported in this paper.

Intravenous patient-controlled analgesia does not increase the risk of postoperative delirium compared to patient-controlled epidural analgesia: a propensity score-matched retrospective cohort study Miyoshi, H. Nakamura, R. Noda, Y. Yokomi, H. Kamiya, S. Morio, A. Watanabe, T. Narasaki, S. Toyota, Y. Saeki, N. Hamada, H. Tsutsumi, Y. M. Ann Palliat Med 2021

Patient-controlled analgesia (PCA)
epidural analgesia
opioid
postoperative delirium (POD)

Standardized Semistructured Psychosocial Evaluation Before Stem Cell Transplantation Predicts Delirium After Transplant Mishkin, A. D. Schmajuk, M. Reshef, R. Lopez-Pintado, S. Mapara, M. Y. Shapiro, P. A. J Acad Consult Liaison Psychiatry 2021

*cancer (PSY0140)
*consultation-liaison psychiatry (PSY0230)
*psycho-oncology (PSY0550)
*transplantation (PSY0710)

Pattern of Brain Injury in Patients With Thrombotic Thrombocytopenic Purpura in the Precaplacizumab Era Mirouse, A. Legriel, S. Dumas, G. Labro, G. Veyradier, A. Zafrani, L. Valade, S. Hourmant, Y. Boutboul, D. Darmon, M. Coppo, P. Mariotte, E. Azoulay, E. Crit Care Med 2021

Adult
Brain Injuries/epidemiology/*etiology
Cohort Studies
Female
Humans
Intensive Care Units/organization & administration/statistics & numerical data
Male
Middle Aged
Prognosis
Prospective Studies
Purpura, Thrombotic Thrombocytopenic/*complications/epidemiology

Postoperative delirium is a risk factor for complications and poor outcome after total hip and knee arthroplasty Meyer, M. Götz, J. Parik, L. Renkawitz, T. Grifka, J. Maderbacher, G. Kappenschneider, T. Weber, M. Acta Orthop 2021

Geriatrics, Surgery, Postoperative delirium, Elective joint replacement

Why should you stay one night? Prospective observational study of enhanced recovery in elderly patients Melegari, G. Albertini, G. Romani, A. Malaguti, S. Traccitto, F. Giuliani, E. Cavallini, G. M. Bertellini, E. Barbieri, A. Aging Clin Exp Res 2021

Aged
*Delirium
Humans
Incidence
Postoperative Complications
Prospective Studies
Delirium
Elderly patients
Perioperative management
Surgery

Inhaled isoflurane via the anaesthetic conserving device versus propofol for sedation of invasively ventilated patients in intensive care units in Germany and Slovenia: an open-label, phase 3, randomised controlled, non-inferiority trial Meiser, A. Volk, T. Wallenborn, J. Guenther, U. Becher, T. Bracht, H. Schwarzkopf, K. Knafelj, R. Faltlhauser, A. Thal, S. C. Soukup, J. Kellner, P. Drüner, M. Vogelsang, H. Bellgardt, M. Sackey, P. Lancet Respir Med 2021

Isoflurane, ICU, Propofol, Invasive ventilation, RASS

Perioperative Considerations for Patients with a Known Diagnosis of Dementia McSwain, J. R. Sirianni, J. M. Wilson, S. H. Adv Anesth 2021

Alzheimer’s dementia
Dementia
Intraoperative considerations
Multidisciplinary care
Perioperative considerations
Postoperative considerations
Postoperative delirium
Preoperative evaluation
interest to declare with regards to this article. There is no external funding to
report. All authors fully participated in the research, writing, and editing of this
article.

The relationship between frailty and delirium: insights from the 2017 Delirium Day study Mazzola, P. Tassistro, E. Di Santo, S. Rossi, E. Andreano, A. Valsecchi, M. G. Cherubini, A. Marengoni, A. Mossello, E. Bo, M. Inzitari, M. Di Bari, M. Udina, C. Latronico, N. Paolillo, C. Morandi, A. Bellelli, G. Age Ageing 2021

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology
*Frailty/diagnosis
Geriatric Assessment
Humans
Prospective Studies
Risk Factors
*Delirium Day
*delirium
*frailty
*mortality
*older people

Absence of Longer Reorientation Times in Patients Undergoing Electroconvulsive Therapy and Concomitant Treatment with Lithium Martins-Ascencao, R. Rodrigues-Silva, N. Trovão, N. Clin Psychopharmacol Neurosci 2021

Cognitive dysfunction
Confusion
Electroconvulsive therapy
Lithium
Orientation

Period-Prevalence and Risk Factors for Delirium in a Tertiary Referral ICU: A prospective cohort study Martinez, F. E. Ho, V. W. Brogan, G. Pickering, C. Leung, G. Parrey, J. Charlton, A. Acute Med 2021

Adult
*Delirium/epidemiology/etiology
Humans
Intensive Care Units
Prevalence
Prospective Studies
Referral and Consultation
Risk Factors

Cross-Cultural Adaptation and Validation of the Italian Version of the Observational Scale of Level of Arousal Martella, L. A. Carmisciano, L. Giannotti, C. Signori, A. Pontremoli, R. Giusti, M. Gualco, E. Beccati, V. Marengoni, A. Nencioni, A. Monacelli, F. J Am Med Dir Assoc 2021

Aged
Arousal
*Cross-Cultural Comparison
*Delirium/diagnosis
Humans
Italy
Longitudinal Studies
Middle Aged
Reproducibility of Results
*Delirium
*OSLA validation.
*level of consciousness
*longitudinal assessment
*older adults

Prevalence and management of delirium in community dwelling older people with dementia referred to a memory clinic Manni, B. Federzoni, L. Zucchi, P. Mussi, C. Inzitari, M. Carda, C. A. Fabbo, A. Morandi, A. Aging Clin Exp Res 2021

Aged
*Delirium/diagnosis/epidemiology/therapy
*Dementia/epidemiology
Hospitalization
Humans
Independent Living
Prevalence
Retrospective Studies
Delirium
Dementia
Home care

Impact of a Real-Time, Pharmacist-Led, Intensive Care Unit-Based Feedback Intervention on Analgesia and Sedation Quality Among Mechanically Ventilated Patients Mancheril, B. Kram, B. Schultheis, J. Kram, S. Trammel, M. Liu, B. Jordan, W. Cox, C. E. J Nurs Care Qual 2021

*Analgesia
*Delirium
Feedback
Humans
Hypnotics and Sedatives
Intensive Care Units
Pain
Pharmacists
Prospective Studies
Respiration, Artificial

A New ICU Delirium Prevention Bundle to Reduce the Incidence of Delirium: A Randomized Parallel Group Trial Malik, A. K. Baidya, D. K. Anand, R. K. Subramaniam, R. Indian J Crit Care Med 2021

Delirium
Intensive care unit
Mechanical ventilation

Risk factors associated with the development of delirium in general ICU patients. A prospective observational study Lobo-Valbuena, B. Gordo, F. Abella, A. Garcia-Manzanedo, S. Garcia-Arias, M. M. Torrejón, I. Varillas-Delgado, D. Molina, R. PLoS One 2021

Delirium, ICU Delirium, CAM-ICU, Clinical Frailty Scale, Length of stay, Readmission rate

Incidence, Predictors and Outcomes of Delirium in Complicated Type B Aortic Dissection Patients After Thoracic Endovascular Aortic Repai Liu, J. Yang, F. Luo, S. Li, C. Liu, W. Liu, Y. Huang, W. Xie, E. Chen, L. Su, S. Yang, X. Geng, Q. Luo, J. Clin Interv Aging 2021

*Aneurysm, Dissecting/surgery
*Aortic Aneurysm, Thoracic/surgery
*Blood Vessel Prosthesis Implantation
Cross-Sectional Studies
*Delirium/epidemiology
*Endovascular Procedures
Humans
Incidence
Male
Retrospective Studies
Risk Factors
Time Factors
Treatment Outcome
hybrid procedure
outcomes
postoperative delirium
predictors
thoracic endovascular aortic repair
type B aortic dissection

Dynamic Delirium Severity Trajectories and Their Association With 2-Year Healthcare Utilization and Mortality Outcomes Lindroth, H. Mohanty, S. Ortiz, D. Gao, S. Perkins, A. J. Khan, S. H. Boustani, M. A. Khan, B. A. Crit Care Explor 2021

delirium
delirium severity
healthcare utilization
mortality
trajectories

Intraoperative Oxygen Concentration and Postoperative Delirium After Laparoscopic Gastric and Colorectal Malignancies Surgery: A Randomized, Double-Blind, Controlled Trial Lin, X. Wang, P. Liu, D. W. Guo, Y. W. Xie, C. H. Wang, B. Dong, R. Sun, L. X. Wang, M. S. Bi, Y. L. Clin Interv Aging 2021

Aged
Aged, 80 and over
Colorectal Neoplasms/surgery
Delirium/*blood/etiology
Digestive System Surgical Procedures/adverse effects/*methods
Double-Blind Method
Humans
Laparoscopy/adverse effects
Male
Oxygen/*blood
Postoperative Complications/*blood/etiology
Postoperative Period
intraoperative oxygen concentration
malignancy
postoperative delirium
conflicts of interest to report.

Incidence of delirium following hospitalization of elderly people with fractures: risk factors and mortality Lima, B. R. Nunes, B. K. G. Guimarães, Lcdc Almeida, L. F. Pagotto, V. Rev Esc Enferm USP 2021

Aged
Aged, 80 and over
*Delirium/epidemiology/etiology
Hospitalization
Humans
Incidence
Male
Prospective Studies
Risk Factors

Regional Nerve Block Decreases the Incidence of Postoperative Delirium in Elderly Hip Fracture Lim, E. J. Koh, W. U. Kim, H. Kim, H. J. Shon, H. C. Kim, J. W. J Clin Med 2021

delirium
hip fracture
nerve block
opioids
pain

Effects of perioperative interventions for preventing postoperative delirium: A protocol for systematic review and meta-analysis of randomized controlled trials Li, X. Wang, Y. Liu, J. Xiong, Y. Chen, S. Han, J. Xie, W. Wu, Q. Medicine (Baltimore) 2021

Delirium/*prevention & control
Humans
Postoperative Complications/prevention & control
Preoperative Period
Randomized Controlled Trials as Topic
Research Design

Developing a machine learning model to identify delirium risk in geriatric internal medicine inpatients Li, Q. Zhao, Y. Chen, Y. Yue, J. Xiong, Y. Eur Geriatr Med 2021

Delirium
Elderly
Internal medicine
Machine learning
Predictive model

Development and validation of a risk score for predicting postoperative delirium after major abdominal surgery by incorporating preoperative risk factors and surgical Apgar score Li, G. H. Zhao, L. Lu, Y. Wang, W. Ma, T. Zhang, Y. X. Zhang, H. J Clin Anesth 2021

Bootstrapping
Elastic net regression
Major open abdominal surgery
Postoperative delirium prediction
Surgical Apgar score

Non-Pharmacological Nursing Interventions for Prevention and Treatment of Delirium in Hospitalized Adult Patients: Systematic Review of Randomized Controlled Trials Lee, Y. Lee, J. Kim, J. Jung, Y. Int J Environ Res Public Health 2021

Adult
Cognition
*Delirium/prevention & control
Ear Protective Devices
Humans
Patients
Randomized Controlled Trials as Topic
*delirium
*hospitalization
*non-pharmacologic intervention
*nursing intervention
*systematic review

Association of natural light exposure and delirium according to the presence or absence of windows in the intensive care unit Lee, H. J. Bae, E. Lee, H. Y. Lee, S. M. Lee, J. Acute Crit Care 2021

delirium
intensive care unit
light

Knowledge, barriers, and training needs of nurses working in delirium care Lee, G. Roh, Y. S Nurs Crit Care 2021

barrier
delirium
knowledge
nurse
performance

Causes and Predictors of 30-Day Readmission in Elderly Patients With Delirium Lau, H. L. Patel, S. D. Garg, N. Neurol Clin Pract 2021

Readmission rate, Delirium, Hospitalization, Length of stay, Post discharge care

Comparison of Antipsychotics for the Treatment of Patients With Delirium and QTc Interval Prolongation: A Clinical Decision Analysis Kurisu, K. Yoshiuchi, K. Front Psychiatry 2021

QTc prolongation
antipsychotics
clinical decision analysis
delirium
quetiapine
or financial relationships that could be construed as a potential conflict of
interest.

The Polish Version of the Nursing Delirium Screening Scale (NuDESC PL)-Experience of Using in Nursing Practice in Cardiac Surgery Intensive Care Unit Krupa, S. Dorota, O. Friganovic, A. Mędrzycka-Dąbrowska, W. Jurek, K. Int J Environ Res Public Health 2021

Cardiac Surgical Procedures/adverse effects
*Delirium/diagnosis
Humans
Intensive Care Units
*Nurses
Poland
*delirium
*disorientation
*nursing delirium screening scale
*screening

Associations of delirium with urinary tract infections and asymptomatic bacteriuria in adults aged 65 and older: A systematic review and meta-analysis Krinitski, D. Kasina, R. Klöppel, S. Lenouvel, E. J Am Geriatr Soc 2021

asymptomatic bacteriuria
delirium
urinary tract infection

Prevalence and Factors Affecting Postoperative Delirium in a Neurosurgical Intensive Care Unit Kose, G. Şirin, K. Inel, M. B. Mertoglu, S. Aksakal, R. Kurucu, Ş J Neurosci Nurs 2021

Cross-Sectional Studies
*Delirium
Humans
*Intensive Care Units
*Neurosurgery
Postoperative Complications
Prevalence
Prospective Studies
Risk Factors

Effect of hypertension and medication use regularity on postoperative delirium after maxillofacial tumors radical surgery Kong, S. Wang, J. Xu, H. Wang, K. Oncotarget 2021

hypertension
oral tumor surgery
postoperative delirium
the elderly
respect to the research, authorship and/or publication of this article.

Perioperative Electroencephalogram Spectral Dynamics Related to Postoperative Delirium in Older Patients Koch, S. Windmann, V. Chakravarty, S. Kruppa, J. Yürek, F. Brown, E. N. Winterer, G. Spies, C. Anesth Analg 2021

Electroencephalography, Postoperative delirium, Surgery, Spectral edge frequency

Is dislocation following total hip arthroplasty caused while suffering from delirium? Kobayashi, T. Morimoto, T. Sonohata, M. Mawatari, M. Nagoya J Med Sci 2021

dislocation
postoperative delirium
total hip arthroplasty

Availability of preoperative neutrophil-lymphocyte ratio to predict postoperative delirium after head and neck free-flap reconstruction: A retrospective study Kinoshita, H. Saito, J. Takekawa, D. Ohyama, T. Kushikata, T. Hirota, K. PLoS One 2021

Postoperative delirium, ICU delirium, Neutrophil-lymphocyte ratio, Surgery, Length of Stay

Delirium risk of histamine-2 receptor antagonists and proton pump inhibitors: A study based on the adverse drug event reporting database in Japan Kikkawa, N. Sogawa, R. Monji, A. Sumi, S. Murakawa-Hirachi, T. Kubo, T. Eguchi, Y. Miyamoto, Y. Kamo, M. Tobita, S. Yukawa, M. Uchida, R. Egoshi, M. Shimanoe, C. Gen Hosp Psychiatry 2021

Delirium
Histamine-2 receptor antagonist
Proton pump inhibitor

Delirium in neurosurgery: a systematic review and meta-analysis Kappen, P. R. Kakar, E. Dirven, C. M. F. van der Jagt, M. Klimek, M. Osse, R. J. Vincent, Apje Neurosurg Rev 2021

Delirium
Incidence rates
Neurosurgery
Screening tools

Risk factors for postoperative delirium and subsyndromal delirium in older patients in the surgical ward: A prospective observational study Kanno, M. Doi, M. Kubota, K. Kanoya, Y. PLoS One 2021

Postoperative delirium, Subsyndromal delirium, Surgery, CAM

Diagnostic accuracy and clinical applicability of the Swedish version of the 4AT assessment test for delirium detection, in a mixed patient population and setting Johansson, Y. A. Tsevis, T. Nasic, S. Gillsjö, C. Johansson, L. Bogdanovic, N. Kenne Sarenmalm, E BMC Geriatr 2021

Aged
*Delirium/diagnosis/epidemiology
Geriatric Assessment
Humans
Reproducibility of Results
Sensitivity and Specificity
Sweden/epidemiology
*4at
*Applicability
*Delirium
*Diagnostic accuracy
*Qualitative content analysis
*Validation study

In-Hospital Delirium as a Prognostic Factor for New Cognitive Disorder in a 1-Year Post-Hip Fracture Follow-Up Jaatinen, R. Luukkaala, T. Hongisto, M. T. Helminen, H. Nuotio, M. S. Dement Geriatr Cogn Disord 2021

Cognition
Delirium
Hip fracture
Outcome
Prognosis

Italian version of the short 10/66 dementia diagnostic schedule: a validation study Ibnidris, A. Piumatti, G. Carlevaro, F. Fadda, M. Magno, F. Magistro, D. Albanese, E. BMJ Open 2021

Aged
Cross-Sectional Studies
*Dementia/diagnosis
Female
Humans
Italy/epidemiology
Male
Middle Aged
ROC Curve
Switzerland
*delirium & cognitive disorders
*dementia
*old age psychiatry

A Machine Learning-Based Algorithm for the Prediction of Intensive Care Unit Delirium (PRIDE): Retrospective Study Hur, S. Ko, R. E. Yoo, J. Ha, J. Cha, W. C. Chung, C. R. JMIR Med Inform 2021

clinical prediction
delirium
electronic health record
intensive care unit
machine learning

The effect of evidence-based cluster nursing intervention on the incidences of delirium and the prognoses of ICU patients Huang, S. Xu, J. Du, Y. Wang, Y. Wei, H. Wei, G. Hu, M. Am J Transl Res 2021

Evidence-based medicine
Icu
cluster nursing intervention
delirium
prognosis

Impact of dexmedetomidine supplemented analgesia on delirium in patients recovering from orthopedic surgery: A randomized controlled tria Hong, H. Zhang, D. Z. Li, M. Wang, G. Zhu, S. N. Zhang, Y. Wang, D. X. Sessler, D. I. BMC Anesthesiol 2021

Delirium
Dexmedetomidine
Elderly
Orthopedic Procedures
Postoperative Period

Effects of a simulation-based education programme on delirium care for critical care nurses: A randomized controlled trial Ho, M. H. Yu, L. F. Lin, P. H. Chang, H. R. Traynor, V. Huang, W. C. Montayre, J. Chen, K. H. J Adv Nurs 2021

Clinical Competence
Critical Care
*Delirium
Humans
*Nurses
Taiwan
competence
confidence
delirium
knowledge
nurses
simulation

Postoperative Delirium in Older Patients: A Systematic Review of Assessment and Incidence of Postoperative Delirium Ho, M. H. Nealon, J. Igwe, E. Traynor, V. Chang, H. R. Chen, K. H. Montayre, J. Worldviews Evid Based Nurs 2021

Aged
Checklist
Cohort Studies
*Delirium/epidemiology/etiology
Humans
Incidence
Risk Factors
data pooling
epidemiology
geriatrics
gerontology
healthcare outcomes
meta-analysis
nervous system diseases
neurology
patient outcomes

Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) Helfand, B. K. I. Detroyer, E. Milisen, K. Adamis, D. Metzger, E. D. Boudreaux, E. D. Inouye, S. K. Jones, R. N. Am J Geriatr Psychiatry 2021
Association between genetic variants of the cholinergic system and postoperative delirium and cognitive dysfunction in elderly patients Heinrich, M. Sieg, M. Kruppa, J. Nürnberg, P. Schreier, P. H. Heilmann-Heimbach, S. Hoffmann, P. Nöthen, M. M. Janke, J. Pischon, T. Slooter, A. J. C. Winterer, G. Spies, C. D. BMC Med Genomics 2021

Chrm2
Chrm4
Genome-wide association study
Neurocognitive disorder

Risk of delirium and impaired neurological outcome associated with delay in neurorehabilitation after acquired brain injury Hansen, P. M. Lauridsen, J. T. Frandsen, N. S. Dan Med J 2021

*Brain Injuries
*Delirium/etiology
Glasgow Coma Scale
Humans
*Neurological Rehabilitation
*Stroke

Prevalence, Risk Factors, and Impact of Delirium on Hospitalized Older Adults With Dementia: A Systematic Review and Meta-Analysis Han, Q. Y. C. Rodrigues, N. G. Klainin-Yobas, P. Haugan, G. Wu, X. J Am Med Dir Assoc 2021

Dementia
delirium
delirium superimposed on dementia
meta-analysis
older adults
prevalence
risk factors

Urinary albumin creatinine ratio associated with postoperative delirium in elderly patients undergoing elective non-cardiac surgery: A prospective observational study Guan, H. L. Liu, H. Hu, X. Y. Abdul, M. Dai, M. S. Gao, X. Chen, X. F. Zhou, Y. Sun, X. Zhou, J. Li, X. Zhao, Q. Zhang, Q. Q. Wang, J. Han, Y. Cao, J. L. CNS Neurosci Ther 2021

delirium
elderly patient
the blood-brain barrier
urinary albumin creatinine ratio

Cognitive Impairment and Delirium in Older Patients Undergoing Major Head and Neck Surgery Goldstein, D. P. Blasco, M. de Almeida, J. Su, J. Xu, W. Cohen, M. Sklar, M. Alibhai, S Otolaryngol Head Neck Surg 2021

clock draw test
cognitive impairment
delirium
head neck surgery
older patients

What prompts patients to present with delirium? Gibb, K. Krywonos, A. Shah, R. Jha, A. Davis, D. Eur Geriatr Med 2021

Adult
Aged, 80 and over
Caregivers
*Delirium/diagnosis
Hospitalization
Humans
Surveys and Questionnaires
*Awareness
*Delirium
*Recognition
*Response

Admission Systolic Blood Pressure Predicts Post-Operative Delirium of Acute Aortic Dissection Patients in the Intensive Care Unit Fu, Z. Xu, Q. Zhang, C. Bai, H. Chen, X. Zhang, Y. Luo, W. Lin, G. Int J Gen Med 2021

acute Stanford type A aortic dissection
intensive care unit
major surgery
post-operative delirium
systolic blood pressure

Postoperative Delirium in Patients After Brain Tumor Surgery French, J. Weber, T. Ge, B. Litofsky, N. S. World Neurosurg 2021

Confusion assessment method
Delirium
Recognition
Tumor resection

Physical Restraints and Post-Traumatic Stress Disorder in Survivors of Critical Illness. A Systematic Review and Meta-analysis Franks, Z. M. Alcock, J. A. Lam, T. Haines, K. J. Arora, N. Ramanan, M. Ann Am Thorac Soc 2021

Adult
*Critical Illness
Humans
Intensive Care Units
Randomized Controlled Trials as Topic
Restraint, Physical
*Stress Disorders, Post-Traumatic/etiology/prevention & control
Survivors
*critical care
*delirium
*physical restraint
*post-traumatic stress disorder
*post–intensive care syndrome

Long-Term Outcomes in ICU Patients with Delirium: A Population-based Cohort Study Fiest, K. M. Soo, A. Hee Lee, C. Niven, D. J. Ely, E. W. Doig, C. J. Stelfox, H. T. Am J Respir Crit Care Med 2021

Adolescent
Adult
Aged
Aged, 80 and over
Alberta/epidemiology
Critical Illness
Delirium/*mortality
Facilities and Services Utilization/*statistics & numerical data
Female
Follow-Up Studies
Humans
*Intensive Care Units
Male
Middle Aged
Patient Discharge
Prognosis
Propensity Score
Retrospective Studies
Survival Analysis
Young Adult
*critical care
*delirium
*mortality

The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial Fazlollah, A. Babatabar Darzi, H. Heidaranlu, E. Moradian, S. T. Complement Ther Med 2021

*Cardiac Surgical Procedures/adverse effects
*Delirium/etiology/therapy
Humans
*Massage
*Musculoskeletal Manipulations
Sleep
*Sleep Wake Disorders/etiology/therapy
Cardiac surgical procedure
Delirium
Massage
Pain measurement
Sleep hygiene

A delirium prevalence audit and a pre and post evaluation of an interprofessional education intervention to increase staff knowledge about delirium in older adults Ewens, B. Seaman, K. Whitehead, L. Towell-Barnard, A. Young, M. BMC Nurs 2021

Delirium
Delirium assessment
Delirium knowledge
Interprofessional education, quality improvement
Symptom recognition

Anaesthetic depth and delirium after major surgery: a randomised clinical trial Evered, L. A. Chan, M. T. V. Han, R. Chu, M. H. M. Cheng, B. P. Scott, D. A. Pryor, K. O. Sessler, D. I. Veselis, R. Frampton, C. Sumner, M. Ayeni, A. Myles, P. S. Campbell, D. Leslie, K. Short, T. G. Br J Anaesth 2021

anaesthesia
bispectral index
cognitive dysfunction
delirium
electroencephalography
postoperative delirium

Association of preoperative frailty with postoperative delirium in elderly orthopedic trauma patients Esmaeeli, S. Franco-Garcia, E. Akeju, O. Heng, M. Zhou, C. Azocar, R. J. Quraishi, S. A. Aging Clin Exp Res 2021

Cognition
Delirium
Frailty
Postoperative delirium
Trauma

Prevention of postoperative delirium after cardiovascular surgery: A team-based approach Enomoto, K. Kosaka, S. Kimura, T. Matsubara, M. Kitada, Y. Mieno, M. Okamura, H. J Thorac Cardiovasc Surg 2021

Delirium Team Approach program
benzodiazepine
cardiovascular surgery
postoperative delirium

Serum Levels of S100β, Neuron-Specific Enolase, Glial Fibrillary Acidic Protein in Kidney Transplant Recipients and Donors: A Prospective Cohort Study Dinc, B. Yılmaz, V. T. Aslan, M. Aycan, I. O. Kiraz, N. Kisaoglu, A. Dandin, O. Hadimioglu, N. Ertug, Z. Transplant Proc 2021

Nephrectomy, Kidney transplant, Neuromarkers, Postoperative delirium

Delirium and Its Pharmacological Causes in Older People, Part 1 DeMaagd, G. A. DeMaagd, D. R. Philip, A. Coalter, C. F. Sr Care Pharm 2021

Aged
*Delirium/chemically induced/diagnosis/epidemiology
Human

Potentially inappropriate prescribing in dementia, multi-morbidity and incidence of adverse health outcomes Delgado, J. Jones, L. Bradley, M. C. Allan, L. M. Ballard, C. Clare, L. Fortinsky, R. H. Hughes, C. M. Melzer, D. Age Ageing 2021

Aged
Aged, 80 and over
*Dementia/diagnosis/drug therapy/epidemiology
England/epidemiology
Humans
*Inappropriate Prescribing
Incidence
Multimorbidity
Outcome Assessment, Health Care
Potentially Inappropriate Medication List
Retrospective Studies
*Alzheimer’s
*Beer’s
*Parkinson’s
*delirium
*hospitalisation
*misprescribing
*mortality
*older people
*vascular dementia

The Nexus Between Sleep Disturbance and Delirium Among Intensive Care Patients Delaney, L. J. Litton, E. Van Haren, F. Crit Care Nurs Clin North Am 2021

Critical Care
*Delirium/epidemiology
Humans
Intensive Care Units
Sleep
*Sleep Wake Disorders/epidemiology
Delirium
Intensive care
Light
Noise
Sleep disturbance

Opportunities for quality improvement in the morbidity pattern of older adults undergoing pulmonary lobectomy for cancer De León, L. E. Rochefort, M. M. Bravo-Iñiguez, C. E. Fox, S. W. Tarascio, J. N. Cardin, K. DuMontier, C. Frain, L. N. Jaklitsch, M. T. J Geriatr Oncol 2021

Aged
Humans
Length of Stay
*Lung Neoplasms/surgery
Morbidity
Postoperative Complications/epidemiology
*Quality Improvement
Retrospective Studies
Thoracic Surgery, Video-Assisted
Thoracotomy
*Lobectomy
*Minimally invasive surgery
*Morbidity
*Older adult
*Oncology outcomes
*Postoperative outcomes
*Thoracic surgery

Palliative sedation in patients with advanced cancer in a specialized unit in a middle-income country: A retrospective cohort study de Araujo, C. Z. S. de Araújo, L. Z. S. Nassar Junior, A. P. Palliat Support Care 2021

Cancer
Cancer care facilities
Deep sedation
End-of-life care
Palliative care

Development and Implementation of a Multicomponent Protocol to Promote Sleep and Reduce Delirium in a Medical Intensive Care Unit Darby, A. Northam, K. Austin, C. A. Chang, L. Campbell-Bright, S Ann Pharmacother 2021

critical care
mechanical ventilators
quality assurance
sedatives
sleep disorders

Effect of Interventions With a Clinical Decision Support System for Hospitalized Older Patients: Systematic Review Mapping Implementation and Design Factors Damoiseaux-Volman, B. A. van der Velde, N. Ruige, S. G. Romijn, J. A. Abu-Hanna, A. Medlock, S. JMIR Med Inform 2021

aged
clinical decision support systems
geriatrics
hospital
quality of care

Sevoflurane-Remifentanil Versus Propofol-Remifentanil Anesthesia During Noncardiac Surgery for Patients with Coronary Artery Disease - A Prospective Study Between 2016 and 2017 at a Single Center Dai, Z. Lin, M. Li, Y. Gao, W. Wang, P. Lin, J. Wan, Z. Jiang, Y. Med Sci Monit 2021

Acute Coronary Syndrome, Coronary Artery Disease, Propofol

Symptom trajectories for palliative care inpatients with and without hyperactive delirium in the last week of life Dai, Y. Walpole, G. Ding, J. Scanlon, C. Ho, L. Khoo, R. H. Huang, C. Cook, A. William, L. Johnson, C. E. J Adv Nurs 2021

end of life
hyperactive delirium
inpatient palliative care
nurse caring
symptom trajectory

Subtypes of delirium after ischaemic stroke-predisposing factors and outcomes: a prospective observational study (PROPOLIS) Czyzycki, M. Klimiec-Moskal, E. Chrobak, A. A. Pera, J. Slowik, A. Dziedzic, T. Eur J Neurol 2021

delirium
motor subtypes
neuropsychiatric disturbances
outcome
stroke

Effectiveness of a Delirium Prevention Initiative on an Inpatient Neuroscience Unit Cyrus, T. Wenthold, R. Hall, B. Tu, L. Hedquist, K. Omodt, J. Kozub, E. Guthrie, P. F. J Neurosci Nurs 2021

Clinical Competence
*Delirium/prevention & control
Humans
Inpatients
*Nurses
Quality Improvement

Association Between Cerebral Desaturation and Postoperative Delirium in Thoracotomy With One-Lung Ventilation: A Prospective Cohort Study Cui, F. Zhao, W. Mu, D. L. Zhao, X. Li, X. Y. Wang, D. X. Jia, H. Q. Dai, F. Meng, L. Anesth Analg 2021

Aged
Cerebrovascular Circulation/*physiology
Cohort Studies
Delirium/diagnosis/*etiology/physiopathology
Female
Humans
Male
Middle Aged
One-Lung Ventilation/*adverse effects/trends
Postoperative Cognitive Complications/diagnosis/*etiology/physiopathology
Prospective Studies
Thoracotomy/*adverse effects/trends

Factors for Timely Identification of Possible Occurrence of Delirium in Palliative Care: A Prospective Observational Study Corli, O. Santucci, C. Uggeri, S. Bosetti, C. Cattaneo, M. Ermolli, D. Varrassi, G. Myrcik, D. Paladini, A. Rekatsina, M. Gerosa, C. Ornaghi, M. Roccasalva, A. Santambrogio, P. Beretta, M. Adv Ther 2021

*Delirium/chemically induced/diagnosis/epidemiology
Hospitalization
Humans
*Palliative Care
Proportional Hazards Models
Prospective Studies
Risk Factors
*Causality
*Clinical predisposing factors
*Delirium

A Processed Electroencephalogram-Based Brain Anesthetic Resistance Index Is Associated With Postoperative Delirium in Older Adults: A Dual Center Study Cooter Wright, M. Bunning, T. Eleswarpu, S. S. Heflin, M. T. McDonald, S. R. Lagoo-Deenadalayan, S. Whitson, H. E. Martinez-Camblor, P. Deiner, S. G. Berger, M. Anesth Analg 2021

age factors, anesthesia, methods, delirium, surgery/prevention & control, Electroencephalography, drug effects

Implementation and Routinization of the ABCDE Bundle: A Mixed Methods Evaluation Collinsworth, A. W. Brown, R. Cole, L. Jungeblut, C. Kouznetsova, M. Qiu, T. Richter, K. M. Smith, S. Masica, A. L. Dimens Crit Care Nurs 2021

Adult
Critical Care
*Delirium
Humans
Intensive Care Units
Respiration, Artificial
Surveys and Questionnaires

Prediction of delirium using data mining: A systematic review Chua, S. J. Wrigley, S. Hair, C. Sahathevan, R J Clin Neurosci 2021

Area Under Curve
Data Mining
*Delirium/diagnosis/epidemiology
Humans
Length of Stay
Retrospective Studies
Association mining
Big data
Delirium
Machine learning
Systematic review
competing financial interests or personal relationships that could have appeared to
influence the work reported in this paper.

Determinants of Non-emergency Use of Control Interventions in Older Canadian Psychiatric Inpatients: Analysizing the InterRAI Mental Health Electronic Health Records Cheung, G. Mah, T. M. Barak, Y. Hirdes, J. P. Front Psychiatry 2021

aggression
control interventions
delirium
geriatric psychiatry
restraints
or financial relationships that could be construed as a potential conflict of
interest.

Assessment of preoperative frailty and identification of patients at risk for postoperative delirium in cardiac intensive care units: a prospective observational study Cheng, H. W. Liu, C. Y. Chen, Y. S. Shih, C. C. Chen, W. Y. Chiou, A. F. Eur J Cardiovasc Nurs 2021

Anxiety
Arrhythmia
Cardiac surgery
Delirium
Depression
Frailty

Preoperative prognostic nutritional index is useful factor for predicting postoperative delirium after primary total joint arthroplasty Chen, J. Zheng, C. Zhong, J. Zhao, G. Shi, J. Huang, G. Wei, Y. Wang, S. Yu, J. Xia, J. BMC Musculoskelet Disord 2021

Aged
Arthroplasty
*Delirium/diagnosis/epidemiology/etiology
Humans
*Nutrition Assessment
Prognosis
Retrospective Studies
Malnutrition
Postoperative delirium
Prognostic nutritional index
Risk factor
Total joint arthroplasty

Case-control study on the interplay between immunoparalysis and delirium after cardiac surgery CheheiliSobbi, S. Peters van Ton, A. M. Wesselink, E. M. Looije, M. F. Gerretsen, J. Morshuis, W. J. Slooter, A. J. C. Abdo, W. F. Pickkers, P. van den Boogaard, M. J Cardiothorac Surg 2021

*Cardiac Surgical Procedures/adverse effects
Case-Control Studies
Cytokines
*Delirium/etiology
Humans
Prospective Studies
Tumor Necrosis Factor-alpha
Cardiothoracic surgery
Delirium
Immunity
Intensive care medicine

Diagnostic accuracy of the "4 A's Test" delirium screening tool for the postoperative cardiac surgery ward Chang, Y. Ragheb, S. M. Oravec, N. Kent, D. Nugent, K. Cornick, A. Hiebert, B. Rudolph, J. L. MacLullich, A. M. J. Arora, R. C. J Thorac Cardiovasc Surg 2021

4at
cardiac surgery
nursing
postoperative delirium

Meta-analysis of ICU Delirium Biomarkers and Their Alignment With the NIA-AA Research Framework Chan, C. K. Song, Y. Greene, R. Lindroth, H. Khan, S. Rios, G. Khan, B. Wang, S Am J Crit Care 2021

Alzheimer Disease
Biomarkers
*Delirium/diagnosis
Humans
*Intensive Care Units
National Institute on Aging (U.S.)
United States

Sedation strategy and ICU delirium: a multicentre, population-based propensity score-matched cohort study Casault, C. Soo, A. Lee, C. H. Couillard, P. Niven, D. Stelfox, T. Fiest, K. BMJ Open 2021

Adult
Alberta
Cohort Studies
*Delirium/chemically induced/epidemiology
Female
Humans
Hypnotics and Sedatives/adverse effects
*Intensive Care Units
Length of Stay
Male
Middle Aged
Propensity Score
Respiration, Artificial
Retrospective Studies
*adult intensive & critical care
*delirium & cognitive disorders
*health & safety
*quality in health care

Health outcomes after the implementation of multidisciplinary clinical guidelines for the care of hip fractures Casanova Querol, T. Santiago Bautista, J. M. Lafuente Salinas, M. Güell Farré, E. Girós Torres, J. Martín-Baranera, M. Miralles Basseda, R. Rev Clin Esp (Barc) 2021

Atención continuada
Continued care
Fractura de cadera
Hip fracture
Internal Medicine
Medicina Interna
Orthogeriatrics
Ortogeriatría

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis Burry, L. D. Cheng, W. Williamson, D. R. Adhikari, N. K. Egerod, I. Kanji, S. Martin, C. M. Hutton, B. Rose, L. Intensive Care Med 2021

Adult
Bayes Theorem
*Critical Illness
*Delirium/prevention & control
Humans
Network Meta-Analysis
Randomized Controlled Trials as Topic
Respiration, Artificial/adverse effects
*Critical care
*Delirium
*Non-pharmacological interventions
*Pharmacological
*Prevention
financial relationships with any organizations that might have an interest in the
submitted work in the previous 3 years
no other relationships or activities that
could appear to have influenced the submitted work. BH has previously provided
methodologic advice to Eversana Inc for the conduct of systemic reviews and
meta-analysis on unrelated topics.

Dexmedetomidine for Facilitating Mechanical Ventilation Extubation in Difficult-to-Wean ICU Patients: Systematic Review and Meta-Analysis of Clinical Trials Buckley, M. S. Smithburger, P. L. Wong, A. Fraser, G. L. Reade, M. C. Klein-Fedyshin, M. Ardiles, T. Kane-Gill, S. L. J Intensive Care Med 2021

Adult
Airway Extubation
Critical Care
*Dexmedetomidine
Humans
Intensive Care Units
Length of Stay
*Respiration, Artificial
agitation
delirium
dexmedetomidine
extubation
intensive care
mechanical ventilation
weaning

Risk factors for postoperative delirium: An umbrella review of systematic reviews Bramley, P. McArthur, K. Blayney, A. McCullagh, I. Int J Surg 2021

*Cognitive Dysfunction
*Delirium/epidemiology/etiology
Humans
Length of Stay
Postoperative Complications/epidemiology/etiology
Risk Factors
Systematic Reviews as Topic
Delirium
Prognostic
Risk factor
Surgery
Umbrella review

Inadequate emergence after anesthesia for elective cancer surgery: a single-center cohort study Braga, A. Abelha, F. Braz J Anesthesiol 2021

Cancer surgeries
Emergence delirium
Hypoactive emergence
Inadequate emergence
Quality of recovery

Asthma and delirium episodes during hospitalization Bozek, A. Fiolka, R. Zajac, M. Aging Med (Milton) 2021

asthma
delirium

A pragmatic assessment of proton pump inhibitors vs. histamine type 2 receptor antagonists on clinically important gastrointestinal bleeding and mortality when used for stress ulcer prophylaxis in the ICU Boyd, C. Hassig, T. MacLaren, R. Pharmacotherapy 2021

critical illness
delirium
histamine H2 antagonists
mortality
peptic ulcer prevention and control
proton pump inhibitors
stress

Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. Stroke 2021

MRI, functional
attention
basal ganglia
delirium
incidence
ischemic stroke
prevalence

Preventing Delirium and Promoting Long-Term Brain Health: A Clinical Trial Design for the Perioperative Cognitive Enhancement (PROTECT) Trial Atkins, K. J. Scott, D. A. Silbert, B. Pike, K. E. Evered, L. J Alzheimers Dis 2021

Anesthesia and analgesia
cognition
delirium
dementia
healthy aging
perioperative medicine
prehabilitation
preventive medicine
rehabilitation

Prevalence of Severe Neurocognitive Impairment and Its Association with Socio-Demographics and Functionality Among Ugandan Older Persons: A Hospital-Based Study Atim, L. M. Kaggwa, M. M. Mamun, M. A. Ashaba, S. Maling, S. Clin Interv Aging 2021

Aged
Aged, 80 and over
*Cognition Disorders
Cross-Sectional Studies
Female
Hospitals
Humans
Male
Middle Aged
Prevalence
Uganda/epidemiology
Barthel Index
Mini-Mental Status Examination
Ugandan elderly
dementia
early diagnosis
functionality
neurocognitive disorder
prevalence and associated factors

Clinical Aspects of Palliative Sedation in Prospective Studies. A Systematic Review Arantzamendi, M. Belar, A. Payne, S. Rijpstra, M. Preston, N. Menten, J. Van der Elst, M. Radbruch, L. Hasselaar, J. Centeno, C. J Pain Symptom Manage 2021

*Hospice and Palliative Care Nursing
Humans
Hypnotics and Sedatives/therapeutic use
Palliative Care
Prospective Studies
Retrospective Studies
*Terminal Care
*Palliative sedation
*deep sedation
*hospice care
*palliative care
*palliative medicine
*prospective studies
*sedation
*systematic review
*terminally ill

Psychometric Properties of Nursing Delirium Screening Scale in Patients Admitted to Intensive Care Units Amirajam, Z. Asadi-Noran, E. Molaei, B. Adiban, V. Heidarzadeh, M. Hassanpour-Darghah, M. Indian J Crit Care Med 2021

Delirium
Intensive care
Validity

Delirium researchers' perspectives of the challenges in delirium biomarker research: A qualitative study Amgarth-Duff, I. Hosie, A. Caplan, G. A. Agar, M. PLoS One 2021

Biomarkers/blood
Biomedical Research
Delirium/*blood
Female
Humans
Male
Qualitative Research
*Research Personnel