Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
The effects of elective aortic repair, colorectal cancer surgery and subsequent postoperative delirium on long-term quality of life, cognitive functioning and depressive symptoms in older patients
Authors
Janssen, T. L. de Vries, J. Lodder, P. Faes, M. C. Ho, G. H. Gobardhan, P. D. van der Laan, L.
Year
2020
Journal
Aging & mental health
Abstract

Objectives: This study aimed to demonstrate the impact of elective major abdominal surgery and subsequent postoperative delirium on quality of life (QOL; primary outcome), cognitive functioning and depressive symptoms (secondary outcomes) in older surgical patients.Method: A single-centre, longitudinal prospective cohort study was conducted between November 2015 and June 2018, including patients ≥70 years old who underwent surgery for colorectal cancer or an abdominal aortic aneurysm. They were followed-up at discharge and at 6 and 12 months postoperatively until June 2019. QOL was assessed with the World Health Organization Quality of Life-BREF questionnaire (WHOQOL-BREF). Cognitive functioning was measured with the Mini-Mental State Examination and depressive symptoms with the CES-D 16.Results: In all patients (n = 265), physical and psychological health were significantly lower at discharge compared to baseline (p < 0.001 for both domains). Physical health restored after 6 months, but psychological health remained decreased for the complete study period. Psychological, social and environmental QOL were significantly worse in patients with delirium compared to patients without (p = 0.001, p = 0.006 and p = 0.001 respectively). The cognitive functioning score was significantly lower at baseline in patients with delirium compared to those without (p = 0.006). Patients with delirium had a significantly higher CES-D 16 score compared to those without after 12 months (p = 0.027).Conclusion: Physical and psychological QOL were decreased in the early postoperative period. While physical health was restored after 6 and 12 months, psychological health remained decreased. After 12 months, postoperative delirium resulted in worse psychological, social and environmental QOL and more depressive symptoms. Decreased cognitive functioning may be a risk factor for delirium.

PMID

32054299

Keywords

abdominal aortic aneurysm
abdominal surgery
adult
aortic reconstruction
article
cancer patient
cancer surgery
cognition
cohort analysis
colorectal cancer
controlled study
depression
elective surgery
female
human
major clinical study
male
Mini Mental State Examination
outcome assessment
postoperative delirium
postoperative period
prospective study
psychological well-being
quality of life
questionnaire
risk factor
surgery
surgical patient
World Health Organization

Page(s)
1-10
Issue

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Diagnosis and management of delirium in hospital oncology service Ramírez Zuluaga, L. P. Ruano Restrepo, M. I. Osorio Bermúdez, J. D. Díaz Vallejo, J. A. J Geriatr Oncol 2021

Cancer
Delirium
Hospital oncology services

Preschool Confusion Assessment Method for the Intensive Care Unit-Spanish (psCAM-ICU-S): Cross-Cultural Adaptation and Validation in Colombia Pinzón-Casas, E. Soto-Trujillo, M. Camargo-Agón, L. Henao-Castaño, Á Gualdrón, N. Bonilla-González, C. Front Pediatr 2021

delirium
intensive care units
pediatric
preschool
psychiatry
validation study

Baseline Vulnerabilities May Play a Larger Role than Depth of Anesthesia or Sedation in Postoperative Delirium Pandharipande, P. P. Whitlock, E. L. Hughes, C. G. Anesthesiology 2021

*Anesthesia
*Delirium
Humans

Prediction of Postoperative Delirium in Geriatric Hip Fracture Patients: A Clinical Prediction Model Using Machine Learning Algorithms Oosterhoff, J. H. F. Karhade, A. V. Oberai, T. Franco-Garcia, E. Doornberg, J. N. Schwab, J. H. Geriatr Orthop Surg Rehabil 2021

clinical prediction model
delirium
geriatric trauma
hip fracture
machine learning
personalized medicine

REcognizing DElirium in geriatric Emergency Medicine: The REDEEM risk stratification score Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Mullan, A. F. Bower, S. M. Campbell, R. L. Rabinstein, A. A. Pignolo, R. J. Bellolio, F. Acad Emerg Med 2021

Geriatrics, Emergency department, delirium screening, REDEEM

Evaluation of the 3-Minute Diagnostic Confusion Assessment Method for Identification of Postoperative Delirium in Older Patients Oberhaus, J. Wang, W. Mickle, A. M. Becker, J. Tedeschi, C. Maybrier, H. R. Upadhyayula, R. T. Muench, M. R. Lin, N. Schmitt, E. M. Inouye, S. K. Avidan, M. S. JAMA Netw Open 2021

3D-CAM, Postoperative Delirium, Major Elective Surgery, Geriatrics, long-form CAM

Is delirium associated with negative outcomes in older patients with hip fracture: analysis of the 4904 patients 2017-2018 from the Australian and New Zealand hip fracture registry Oberai, T. Woodman, R. Laver, K. Crotty, M. Kerkhoffs, G. Jaarsma, R ANZ J Surg 2021

delirium
hip fracture
outcomes

Postoperative delirium in older patients with cancer: the role of psychological distress and social support O'Hanlon, S. Baxter, M. Hosie, A. Curr Opin Support Palliat Care 2021
Postoperative delirium and neurocognitive disorders Migirov, A. Chahar, P. Maheshwari, K. Curr Opin Crit Care 2021

Aging
*Delirium/diagnosis/etiology/therapy
Humans
Neurocognitive Disorders
*Postoperative Complications/etiology
Postoperative Period

Development of a delirium predictive model for adult trauma patients in an emergency and critical care center: a retrospective study Matsuoka, A. Miike, T. Miyazaki, M. Goto, T. Sasaki, A. Yamazaki, H. Komaki, M. Higuchi, M. Mori, K. Shinada, K. Nakayama, K. Sakurai, R. Asahi, M. Futami, A. Yoshitake, K. Narumi, S. Koba, M. Koami, H. Kawaguchi, A. Murakawa, T. H. Monji, A. Sakamoto, Y. Trauma Surg Acute Care Open 2021

adult
frailty
multiple trauma

Early-onset delirium after spontaneous intracerebral hemorrhage Marrama, F. Kyheng, M. Pasi, M. Pierre Rutgers, M. Moulin, S. Diomedi, M. Leys, D. Cordonnier, C. Hénon, H. Casolla, B. Int J Stroke 2021

Intracerebral hemorrhage
delirium
dementia
long-term outcomes
mortality

An Emergency Department Delirium Screening and Management Initiative: The Development and Refinement of the SCREENED-ED Intervention Mailhot, T. Saczynski, J. S. Malyuta, Y. Inouye, S. K. Darling, C. J Gerontol Nurs 2021

*Delirium/diagnosis/therapy
Delivery of Health Care
*Emergency Medical Services
Emergency Service, Hospital
Humans
Mass Screening

Impact of a multifaceted and multidisciplinary intervention on pain, agitation and delirium management in an intensive care unit: an experience of a Canadian community hospital in conducting a quality improvement project Ma, Z. Camargo Penuela, M. Law, M. Joshi, D. Chung, H. O. Lam, J. N. H. Tsang, J. L. BMJ Open Qual 2021

Canada
*Delirium/diagnosis/prevention & control
Hospitals, Community
Humans
Intensive Care Units
Pain
*Quality Improvement
Translational Science, Biomedical
*clinical practice guidelines
*critical care
*healthcare quality improvement
*implementation science

Prevalence, classification, risk factors and outcome impact of delirium in patients with COVID-19: a meta-analysis protocol for systematic review Lou, B. Guo, J. Liu, Y. Xiong, C. Shi, J. Zhou, C. BMJ Open 2021

*COVID-19/complications
*Delirium/complications/epidemiology
Humans
Meta-Analysis as Topic
Prevalence
Risk Factors
SARS-CoV-2
Systematic Reviews as Topic
*covid-19
*adult intensive & critical care
*delirium & cognitive disorders

Effect of Regional vs General Anesthesia on Incidence of Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: The RAGA Randomized Trial Li, T. Li, J. Yuan, L. Wu, J. Jiang, C. Daniels, J. Mehta, R. L. Wang, M. Yeung, J. Jackson, T. Melody, T. Jin, S. Yao, Y. Wu, J. Chen, J. Smith, F. G. Lian, Q. Jama 2021
Opioid and benzodiazepine use in the emergency department and the recognition of delirium within the first 24 hours of hospitalization Lee, S. Okoro, U. E. Swanson, M. B. Mohr, N. Faine, B. Carnahan, R. J Psychosom Res 2021

Delirium
Emergency department
High-risk medications
Prediction

Awareness and Perspectives among Asian Anesthesiologists on Postoperative Delirium: A Multinational Survey Lee, H. Kim, J. Lee, K. Y. Gan, T. J. Lekprasert, V. Laosuwan, P. Chew, S. T. H. Seet, E. Lim, V. Ti, L. K. J Clin Med 2021

NIR spectroscopy
anesthesiology
consciousness monitors
perioperative care
postoperative cognitive complications
postoperative complications

Utilization of Kotter's Stages and Statistical Process Control to Implement and Sustain Delirium Screening in PICU Kupferschmid, M. Tripathi, S. Pediatr Qual Saf 2021

Delirium, ICU Delirium, ICU morbidity and mortality, Screening compliance, Kotter’s stages

Impact of postoperative delirium on days alive and at home after surgery: a prospective cohort study Kunkel, D. Parker, M. Casey, C. Krause, B. Pearce, R. A. Lennertz, R. Sanders, R. D. Br J Anaesth 2021

Cohort Studies
Delirium/*mortality
Humans
Length of Stay/*statistics & numerical data
Patient Acuity
Postoperative Complications/*mortality
Prospective Studies
*days alive and at home
*delirium
*mortality
*postoperative
*surgery

Delirium in a Tertiary Pediatric Cardiac Intensive Care Unit: Risk Factors and Outcomes Koth, A. M. Chan, T. Tjoeng, Y. L. Watson, R. S. Dervan, L. A. J Intensive Care Med 2021

analgesics
benzodiazepines
child
critical care
critical illness
dexmedetomidine
hypnotics and sedatives
length of stay
opioids
retrospective studies

Postoperative delirium screening tools for post-anaesthetic adult patients in non-intensive care units: A systematic review and meta-analysis Kim, S. Choi, E. Jung, Y. Jang, I. J Clin Nurs 2021

adult nursing
emergence delirium
nursing assessment
postoperative care
systematic review and meta-analyses

Factors Related to Delirium of Intensive Care Unit Patients in Korea: A Systematic Review Kim, N. Y. Ryu, S. A. Kim, Y. H. Iran J Public Health 2021

Delirium
Intensive care units
Systematic review

Risk factors for postoperative delirium in patients with colorectal cancer Kim, H. Park, H. Kim, E. K. J Clin Nurs 2022

*Colorectal Neoplasms/complications/surgery
Cross-Sectional Studies
*Delirium/epidemiology/etiology
Humans
Postoperative Complications/epidemiology
Risk Factors
colorectal cancer
delirium

Influences of remote ischemic preconditioning on postoperative delirium and cognitive dysfunction in adults after cardiac surgery: a meta-analysis of randomized controlled trials Jing, Y. Gao, B. Li, X. Perioper Med (Lond) 2021

Cardiac surgery
Meta-analysis
Postoperative cognitive dysfunction
Postoperative delirium
Remote ischemic preconditioning

Delirium Reduction by Analgesia Management in Hip Fracture surgery (DRAM-HF): Exploration of perceived facilitators and barriers Hunter, C. L. Ni Chroinin, D. McEvoy, L. Chuan, A. Australas J Ageing 2021

*Analgesia
*Delirium/diagnosis/drug therapy/prevention & control
*Hip Fractures/diagnosis/surgery
Humans
Pharmacists
Prospective Studies
delirium
hip fractures
perioperative care

Management of Delirium in the Intensive Care Unit Huang, D. D. Fischer, P. E. Surg Clin North Am 2022

Age Factors
Antipsychotic Agents/therapeutic use
Behavior Therapy/methods
Combined Modality Therapy
Critical Care/*methods
Delirium/diagnosis/etiology/*therapy
Humans
Intensive Care Units
Risk Factors
Antipsychotics
Delirium
Elderly
Intensive care unit
Prevention

Postoperative delirium and quality of life after transcatheter and surgical aortic valve replacement: A prospective observational study Hoogma, D. F. Venmans, E. Al Tmimi, L. Tournoy, J. Verbrugghe, P. Jacobs, S. Fieuws, S. Milisen, K. Adriaenssens, T. Dubois, C. Rex, S. J Thorac Cardiovasc Surg 2021

Savr
Tavi
aortic valve
cardiac surgery
delirium
frailty
postoperative outcome
quality of life

Construction and Application of a Model for Predicting the Risk of Delirium in Postoperative Patients With Type a Aortic Dissection He, J. Ling, Q. Chen, Y. Front Surg 2021

factor
nursing
postoperative delirium
predictive model
type A aortic dissection

The Locus Coeruleus Noradrenaline System in Delirium Hansen, N. Rediske, A. I. Front Aging Neurosci 2021

attention
cognition
delirium
locus coeruleus
noradrenaline

Single bolus dexmedetomidine versus propofol for treatment of pediatric emergence delirium following general anesthesia Han, X. Sun, X. Liu, X. Wang, Q Paediatr Anaesth 2021

dexmedetomidine
pediatric emergence delirium
propofol

Prospective Analysis Between Neutrophil-to-Lymphocyte Ratio on Admission and Development of Delirium Among Older Hospitalized Patients With COVID-19 Fernández-Jiménez, E. Muñoz-Sanjose, A. Mediavilla, R. Martínez-Alés, G. Louzao,, II Andreo, J. Cebolla, S. Bravo-Ortiz, M. F. Bayón, C. Front Aging Neurosci 2021

Covid-19
delirium
hospitalization
neutrophil-to-lymphocyte ratio (NLR)
older adults

Relationship Between Cerebral Hemodynamics, Tissue Oxygen Saturation, and Delirium in Patients With Septic Shock: A Pilot Observational Cohort Study Feng, Q. Ai, M. Huang, L. Peng, Q. Ai, Y. Zhang, L. Front Med (Lausanne) 2021

cerebral oxygen saturation
delirium
sepsis
sepsis-associated delirium
septic shock
tissue oxygen saturation
transcranial Doppler ultrasound

Risk factors for delirium in adult patients receiving specialist palliative care: A systematic review and meta-analysis Featherstone, I. Sheldon, T. Johnson, M. Woodhouse, R. Boland, J. W. Hosie, A. Lawlor, P. Russell, G. Bush, S. Siddiqi, N. Palliat Med 2021

Risk factors
delirium
meta-analysis
palliative care
systematic review

Feasibility trial of weighted blankets as an intervention for emergence delirium in postoperative pediatric patients Eull, D. Zachrison, B. Nickel, A. J Pediatr Nurs 2021

Emergence delirium
Feasibility
Post-anesthesia care unit (PACU)
Watcha scale
Weighted blanket

The LiberAction Project: Implementation of a Pediatric Liberation Bundle to Screen Delirium, Reduce Benzodiazepine Sedation, and Provide Early Mobilization in a Human Resource-Limited Pediatric Intensive Care Unit Di Nardo, M. Boldrini, F. Broccati, F. Cancani, F. Satta, T. Stoppa, F. Genuini, L. Zampini, G. Perdichizzi, S. Bottari, G. Fischer, M. Gawronski, O. Bonetti, A. Piermarini, I. Recchiuti, V. Leone, P. Rossi, A. Tabarini, P. Biasucci, D. Villani, A. Raponi Front Pediatr 2021

benzodiazepine (BDZ)
bundle
delirium
early mobilization
pediatric intensive care
sedation

Outcomes of a Delirium Prevention Program in Older Persons After Elective Surgery: A Stepped-Wedge Cluster Randomized Clinical Trial Deeken, F. Sánchez, A. Rapp, M. A. Denkinger, M. Brefka, S. Spank, J. Bruns, C. von Arnim, C. A. F. Küster, O. C. Conzelmann, L. O. Metz, B. R. Maurer, C. Skrobik, Y. Forkavets, O. Eschweiler, G. W. Thomas, C. JAMA Surg 2021

Delirium, Elective surgery outcomes, Elderly patients, Nonpharmacologic delirium prevention, Delirium Education

Advanced Age Is Associated With Catatonia in Critical Illness: Results From the Delirium and Catatonia Prospective Cohort Investigation Connell, J. Kim, A. Brummel, N. E. Patel, M. B. Vandekar, S. N. Pandharipande, P. Dittus, R. S. Heckers, S. Ely, E. W. Wilson, J. E. Front Psychiatry 2021

age
catatonia
coma
critical illness
delirium
or financial relationships that could be construed as a potential conflict of
interest.

Identifying frequent drug combinations associated with delirium in older adults: Application of association rules method to a case-time-control design Chyou, T. Y. Nishtala, P. S. Pharmacoepidemiol Drug Saf 2021

Aged
Aged, 80 and over
*Delirium/chemically induced/diagnosis/epidemiology
Drug Combinations
Humans
New Zealand
*association rules
*case-time-control design
*delirium
*older people
*pharmacoepidemiology
*pharmacovigilance

Risk Factors and a Nomogram Model Establishment for Postoperative Delirium in Elderly Patients Undergoing Arthroplasty Surgery: A Single-Center Retrospective Study Chen, D. Li, Y. Li, Q. Gao, W. Li, J. Wang, S. Cao, J. Biomed Res Int 2021

Postoperative Delirium, Geriatrics, Knee and Hip Arthroplasty

Detecting Incident Delirium within Routinely Collected Inpatient Rehabilitation Data: Validation of a Chart-Based Method Ceppi, M. G. Rauch, M. S. Sándor, P. S. Gantenbein, A. R. Krishnakumar, S. Albert, M. Meier, C. R. Neurol Int 2021

delirium
neurocognitive disorders
patient-generated health data
rehabilitation
validation study

Spinal Anesthesia with Targeted Sedation based on Bispectral Index Values Compared with General Anesthesia with Masked Bispectral Index Values to Reduce Delirium: The SHARP Randomized Controlled Trial Brown, C. H. Edwards, C. Lin, C. Jones, E. L. Yanek, L. R. Esmaili, M. Gorashi, Y. Skelton, R. Kaganov, D. Curto, R. Lessing, N. L. Cha, S. Colantuoni, E. Neufeld, K. Sieber, F. Dean, C. L. Hogue, C. W. Anesthesiology 2021

Aged
Anesthesia, General/adverse effects/*methods
Anesthesia, Spinal/adverse effects/*methods
Electroencephalography/*methods
Emergence Delirium/*diagnosis/*physiopathology/prevention & control
Female
Humans
Male
Single-Blind Method

Delirium in Cardiac and Cardiovascular Surgical Intensive Care Units Breit, H. Bleck, T. P. Koffman, L. Semin Neurol 2021

Critical Care
*Delirium/diagnosis/etiology/therapy
Humans
Intensive Care Units

Are treatment effects consistent with hypothesized mechanisms of action proposed for postoperative delirium interventions? Reanalysis of systematic reviews Boxell, E. G. Malik, Y. Wong, J. Lee, M. H. Berntsson, H. M. Lee, M. J. Bourne, R. S. McCullagh, I. J. Hind, D. Wilson, M. J. J Comp Eff Res 2021

*Delirium/prevention & control
Humans
*Postoperative Complications
Systematic Reviews as Topic
*aging health
*meta-analysis
*methodology
*surgery

DelIrium VULnerability in GEriatrics (DIVULGE) study: a protocol for a prospective observational study of electroencephalogram associations with incident postoperative delirium Boord, M. S. Davis, D. H. J. Psaltis, P. J. Coussens, S. W. Feuerriegel, D. Garrido, M. I. Bourke, A. Keage, H. A. D BMJ Neurol Open 2021

Eeg
cognitive electrophysiology
event-related potentials
geriatrics
neurophysiology

Patient Factors That Influence Reliable Delirium Assessments in a Medical Intensive Care Unit During the Routine Clinical Practice Back, J. S. Jin, T. Jin, H. Lee, S. M. Clin Nurs Res 2021

Cam-icu
delirium
electronic health records
intensive care units
validation study

Monitoring Delirium in the Intensive Care Unit Practices, perceptions and attitudes of critical care nurses and physicians. A French National Survey Alaterre, C. Fazilleau, C. Constantin, J. M. James, A. Intensive Crit Care Nurs 2021

Critical Care
Critical care nurse
Delirium
Delirium monitoring
Intensive Care Unit
Medical Staff
Practices

Predictors of postoperative delirium in elderly patients following total hip and knee arthroplasty: a systematic review and meta-analysis Zhou, Q. Zhou, X. Zhang, Y. Hou, M. Tian, X. Yang, H. He, F. Chen, X. Liu, T. BMC Musculoskelet Disord 2021

Aged
*Arthroplasty, Replacement, Hip/adverse effects
*Arthroplasty, Replacement, Knee/adverse effects
*Delirium/diagnosis/epidemiology/etiology
Humans
Odds Ratio
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
Postoperative delirium
Predictors
Total hip arthroplasty
Total joint arthroplasty
Total knee arthroplasty

Incidence, characteristics, and outcomes of delirium in patients with noninvasive ventilation: a prospective observational study Zhang, R. Bai, L. Han, X. Huang, S. Zhou, L. Duan, J. BMC Pulm Med 2021

Aged
Aged, 80 and over
Critical Illness
Delirium/*epidemiology
Female
*Hospital Mortality
Hospitals, Teaching
Humans
Incidence
*Intensive Care Units
Logistic Models
Male
Middle Aged
Multivariate Analysis
Noninvasive Ventilation/*adverse effects
Prospective Studies
Risk Factors
Treatment Failure
Delirium
Noninvasive ventilation
Risk factor

A systematic review and meta-analysis of the correlation between operation time and postoperative delirium in total hip arthroplasty Zhang, G. Wang, Z. Wang, D. Jia, Q. Zeng, Y. Ann Palliat Med 2021

*Arthroplasty, Replacement, Hip/adverse effects
Case-Control Studies
*Delirium/etiology
Humans
Postoperative Complications/etiology
Retrospective Studies
*Total hip arthroplasty (THA)
*delirium
*meta-analysis
*operation time

The PREvention Program for Alzheimer's RElated Delirium (PREPARED) cluster randomized trial: a study protocol Wilchesky, M. Ballard, S. A. Voyer, P. McCusker, J. Lungu, O. Champoux, N. Vu, T. T. M. Cole, M. G. Monette, J. Ciampi, A. Belzile, E. Carmichael, P. H. McConnell, T. BMC Geriatr 2021

Aged
*Alzheimer Disease
*Delirium/diagnosis/epidemiology/prevention & control
Frail Elderly
Homes for the Aged
Humans
Randomized Controlled Trials as Topic
Retrospective Studies
*Delirium
*Delirium superimposed on dementia
*Long-term care
*Modifiable risk factors
*Multicomponent intervention
*Nursing

Anaesthetic depth and delirium: a challenging balancing act Whitlock, E. L. Gross, E. R. King, C. R. Avidan, M. S. Br J Anaesth 2021

Anesthesia, General
*Anesthesiology
*Anesthetics/adverse effects
*Delirium/epidemiology
Humans
*anaesthetic sensitivity
*bispectral index
*delirium
*depth of anaesthesia
*precision medicine

Identification of risk factors for postoperative delirium in elderly patients with hip fractures by a risk stratification index model: A retrospective study Wang, Y. Zhao, L. Zhang, C. An, Q. Guo, Q. Geng, J. Guo, Z. Guan, Z. Brain Behav 2021

health services for the elderly
hip fractures
postoperative cognitive complications
risk assessment
risk factors

Association between perioperative hypotension and postoperative delirium and atrial fibrillation after cardiac surgery: A post-hoc analysis of the DECADE trial Wang, J. Mao, G. Malackany, N. Marciniak, D. Donaldson, C. Wakefield, B. Hassan, M. Ruetzler, K. Sessler, D. I. Turan, A. J Clin Anesth 2021

Anesthesia
Atrial fibrillation
Delirium
Hypotension

The effect of the anticholinergic burden on duration and severity of delirium in older hip-surgery patients with and without haloperidol prophylaxis: A post hoc analysis Tillemans, M. P. H. Butterhoff-Terlingen, M. H. Stuffken, R. Vreeswijk, R. Egberts, T. C. G. Kalisvaart, K. J. Brain Behav 2021

anticholinergic burden
delirium
haloperidol
prophylaxis

Refractory hyperactive delirium in the dying: pharmacological management Tham, K. Shiu, A. William, L. Walpole, G. Rashed, S. BMJ Support Palliat Care 2021

delirium
pharmacology
symptoms and symptom management
terminal care

Time to Post-Anesthesia Neurological Evaluation and Hemodynamic Stability in Carotid Endarterectomy Comparing Three General Anesthetic Techniques Targeted to a Preset Bispectral Index Value: A Pilot Study Temmermand, R. Mitrev, L. van Helmond, N. Roberts, D. Lombardi, J. Vuckovic, D. Aana j 2021

Anesthesia, General
*Anesthetics, General/pharmacology
Anesthetics, Intravenous
*Endarterectomy, Carotid
Hemodynamics/drug effects
Humans
Pilot Projects
Piperidines/pharmacology
*Propofol
Prospective Studies
Carotid endarterectomy
general anesthesia
intraoperative stroke
postoperative cognitive dysfunction
postoperative delirium

Delirium During Acute Events in Nursing Home Patients Skretteberg, W. H. Holmefoss, I. Krogseth, M. J Am Med Dir Assoc 2021

Delirium
acute disease
benzodiazepines
nursing home

The impact of emergence delirium on hospital length of stay for children who underwent tonsillectomy/adenotonsillectomy: an observational retrospective study Simonini, A. Vittori, A. Cascella, M. Calevo, M. G. Marinangeli, F. Braz J Anesthesiol 2021

Anesthesia
Children
Dexmedetomidine
Emergence delirium
Length of stay
Pain

Effects of Melatonin on Postoperative Delirium After PCI in Elderly Patients: A Randomized, Single-Center, Double-Blind, Placebo-Controlled Trial Shi, Y. Heart Surg Forum 2021

Effects of Melatonin

Postoperative Delirium

PCI

Elderly Patients

Randomized

Single-Center

Double-Blind

Placebo-Controlled Trial

A Quality Improvement Initiative to Reduce Postoperative Delirium among Cardiac Surgery Patients Sanjanwala, R. M. Hiebert, B. Kent, D. Warren, S. Grocott, H. Arora, R. C. Geriatrics (Basel) 2021

cardiac surgery
care strategies
postoperative care
postoperative delirium
quality improvement

The prevalence of delirium in belgian nursing homes: a cross-sectional evaluation Sabbe, K. van der Mast, R. Dilles, T. Van Rompaey, B. BMC Geriatr 2021

Aged
Aged, 80 and over
Belgium/epidemiology
Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
Female
Humans
Nursing Homes
Prevalence
*Delirium
*delirium point-prevalence
*delirium screening
*long-term care
*nursing homes
*precipitating delirium factors

Family intervention for delirium for patients in the intensive care unit: A systematic meta-analysis Qin, M. Gao, Y. Guo, S. Lu, X. Zhu, H. Li, Y. J Clin Neurosci 2021

Delirium
Family engagement
Family intervention
ICU

Orthogeriatric co-management reduces incidence of delirium in hip fracture patients Pollmann, C. T. Mellingsæter, M. R. Neerland, B. E. Straume-Næsheim, T. Årøen, A. Watne, L. O. Osteoporos Int 2021

*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/epidemiology
Humans
Incidence
Logistic Models
Prospective Studies
Delirium
Hip fracture
Orthogeriatric co-management
Subsyndromal delirium

Accuracy of delirium assessments in critically ill children: A prospective, observational study during routine care Paterson, R. S. Kenardy, J. A. Dow, B. L. De Young, A. C. Pearson, K. Aitken, L. M. Long, D. A. Aust Crit Care 2021

Australia
Child
Child, Preschool
*Critical Illness
*Delirium/diagnosis
Humans
Intensive Care Units
Intensive Care Units, Pediatric
Prospective Studies
*Delirium
*Intensive care units
*Paediatric
*Psychometrics
*Screening
interest to disclose.

Comparative effectiveness of pharmacological interventions to prevent postoperative delirium: a network meta-analysis Park, S. K. Lim, T. Cho, H. Yoon, H. K. Lee, H. J. Lee, J. H. Yoo, S. Kim, J. T. Kim, W. H. Sci Rep 2021

Adult
Antipsychotic Agents/administration & dosage
*Bayes Theorem
Delirium/etiology/*prevention & control
Haloperidol/administration & dosage
Humans
Network Meta-Analysis
Pharmaceutical Preparations/*administration & dosage/classification
Postoperative Complications/etiology/*prevention & control
Randomized Controlled Trials as Topic
Treatment Outcome

Dexmedetomidine, Delirium, and Adverse Outcomes: Analysis of the Society of Thoracic Surgeons Adult Cardiac Surgery Database Pal, N. Abernathy, J. H., 3rd Taylor, M. A. Bollen, B. A. Shah, A. S. Feng, X. Shotwell, M. S. Kertai, M. D. Ann Thorac Surg 2021

Analgesics, Non-Narcotic/adverse effects
Cardiac Surgical Procedures/*adverse effects
Delirium/*epidemiology/etiology
Dexmedetomidine/*adverse effects
Humans
Incidence
Pain, Postoperative/prevention & control
Postoperative Complications/*epidemiology/etiology
*Propensity Score
Retrospective Studies
Societies, Medical/*statistics & numerical data
Thoracic Surgery/*statistics & numerical data
United States/epidemiology

ICU delirium burden predicts functional neurologic outcomes Paixao, L. Sun, H. Hogan, J. Hartnack, K. Westmeijer, M. Neelagiri, A. Zhou, D. W. McClain, L. M. Kimchi, E. Y. Purdon, P. L. Akeju, O. Westover, M. B. PLoS One 2021

ICU delirium

functional neurologic

outcomes

Delirium occurrence and association with outcomes in hospitalized COVID-19 patients Pagali, S. Fu, S. Lindroth, H. Sohn, S. Burton, M. C. Lapid, M. Int Psychogeriatr 2021

Adolescent
Adult
Aged
Aged, 80 and over
COVID-19/complications/*mortality
Child
Child, Preschool
Delirium/complications/*epidemiology
Hospitalization/*statistics & numerical data
Humans
Infant
Infant, Newborn
Intensive Care Units
Length of Stay
Male
Middle Aged
Minnesota/epidemiology
Retrospective Studies
SARS-CoV-2
Young Adult
*COVID-19 severity
*delirium
*hospitalized COVID-19
*outcomes

Risk Factors for Delirium in Older Adults in the Emergency Department: A Systematic Review and Meta-Analysis Oliveira, J. E. Silva L. Berning, M. J. Stanich, J. A. Gerberi, D. J. Murad, M. H. Han, J. H. Bellolio, F. Ann Emerg Med 2021

Aged
Aged, 80 and over
Delirium/*prevention & control
*Emergency Service, Hospital
Geriatric Assessment/*methods
Humans
Risk Assessment
Risk Factors

Factors associated with delirium among survivors of acute respiratory distress syndrome: a nationwide cohort study Oh, T. K. Park, H. Y. Song, I. A. BMC Pulm Med 2021

Critical Care
Delirium
Mortality
Respiratory distress syndrome

Rapid Handheld Continuous Electroencephalogram (EEG) Has the Potential to Detect Delirium in Older Adults Mulkey, M. A. Gantt, L. T. Hardin, S. R. Munro, C. L. Everhart, D. E. Kim, S. Schoeman, A. M. Roberson, D. W. McAuliffe, M. Olson, D. M. Dimens Crit Care Nurs 2021

Aged
Critical Illness
*Delirium/diagnosis
Electroencephalography
Humans
Pilot Projects
Prospective Studies

Delirium and Clusters of Older Patients Affected by Multimorbidity in Acute Hospitals Monacelli, F. Signori, A. Marengoni, A. Di Santo, S. Rossi, E. Valsecchi, M. G. Morandi, A. Bellelli, G. J Am Med Dir Assoc 2021

Delirium
multimorbidity

Major Surgery and Long Term Cognitive Outcomes: The Effect of Postoperative Delirium on Dementia in the Year Following Discharge Mohanty, S. Gillio, A. Lindroth, H. Ortiz, D. Holler, E. Azar, J. Boustani, M. Zarzaur, B. J Surg Res 2021

Dementia
Geriatrics
Postoperative delirium
Surgery

Elevated neuron-specific enolase level is associated with postoperative delirium and detection of phosphorylated neurofilament heavy subunit: A prospective observational study Mietani, K. Hasegawa-Moriyama, M. Inoue, R. Ogata, T. Shimojo, N. Kurano, M. Sumitani, M. Uchida, K. PLoS One 2021

Elevated neuron-specific enolase level

postoperative delirium

phosphorylated neurofilament heavy subunit

prospective observational study

Variations in analgesic, sedation, and delirium management between trauma and non-trauma critically ill children Mehl, S. C. Cunningham, M. E. Chance, M. D. Zhu, H. Fallon, S. C. Naik-Mathuria, B. Ettinger, N. A. Vogel, A. M. Pediatr Surg Int 2021

Analgesia
Children
Critically ill
Delirium
Sedation
Trauma

Simulation Training Exercise to Improve Outcomes of Emergence Delirium in Patients With Posttraumatic Stress Disorder Lovestrand, D. Beaumont, C. D. Calder, M. S. Schmidt, M. Calaro, R. Aana j 2021

Anesthesia
*Emergence Delirium
Humans
Military Personnel
*Simulation Training
*Stress Disorders, Post-Traumatic
Emergence delirium
perianesthesia
perioperative education
posttraumatic stress disorder
simulation

Effects of Glucocorticoids on Postoperative Delirium in Adult Patients Undergoing Cardiac Surgery: A Systematic Review and Meta-analysis Liu, W. Wang, Y. Wang, J. Shi, J. Pan, J. Wang, D. Clin Ther 2021

Glucocorticoids

Postoperative Delirium

Adult

Cardiac Surgery

A Systematic Review

Meta-analysis

The Association Between Preoperative Frailty and Postoperative Delirium: A Systematic Review and Meta-analysis Liu, C. Y. Gong, N. Liu, W. J Perianesth Nurs 2021

delirium
frailty
meta-analysis
perioperative period

A complex intervention to promote prevention of delirium in older adults by targeting caregiver's participation during and after hospital discharge - study protocol of the TRAnsport and DElirium in older people (TRADE) project Leinert, C. Brefka, S. Braisch, U. Denninger, N. Mueller, M. Benzinger, P. Bauer, J. Bahrmann, A. Frey, N. Katus, H. A. Geisler, T. Eschweiler, G. Klaus, J. Seufferlein, T. Schuetze, K. Gebhard, F. Dreyhaupt, J. Muche, R. Pahmeier, K. Biermann-Stallwitz, BMC Geriatr 2021

Aged
Caregivers
*Delirium/diagnosis/epidemiology/prevention & control
Hospitals
Humans
Multicenter Studies as Topic
*Patient Discharge
Pilot Projects
Prospective Studies
Systematic Reviews as Topic
*Caregiver
*Complex intervention
*Delirium
*Dementia
*Discharge
*Family
*Geriatrics
*Older adults
*Transfer
*Transport

Evaluation of Bedside Tests of Attention and Arousal Assessing Delirium in Parkinson's Disease, Dementia, and Older Adults Lawson, R. A. Richardson, S. J. Kershaw, D. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Burn, D. J. Yarnall, A. J. Taylor, J. P. Parker, S. Allan, L. M. J Parkinsons Dis 2021

Delirium
Parkinson disease
arousal
attention
dementia
diganosis

Dexmedetomidine and paralytic exposure after damage control laparotomy: risk factors for delirium? Results from the EAST SLEEP-TIME multicenter trial Krause, C. Kwon, E. Luo-Owen, X. McArthur, K. Cochran-Yu, M. Swentek, L. Burruss, S. Turay, D. Grigorian, A. Nahmias, J. Butt, A. Gutierrez, A. LaRiccia, A. Kincaid, M. Fiorentino, M. N. Glass, N. Toscano, S. Ley, E. Lombardo, S. R. Guillamondegui, O. D. Eur J Trauma Emerg Surg 2021

Damage control laparotomy
Delirium
Non-trauma
Sedation
Trauma

The effects of intraoperative magnesium sulfate administration on emergence agitation and delirium in pediatric patients: a systematic review and meta-analysis of randomized controlled trials Koo, C. H. Koo, B. W. Han, J. Lee, H. T. Lim, D. Shin, H. J. Paediatr Anaesth 2021

complications
emergence delirium
general anesthesia

The Modified Hospital Elder Life Program (HELP) in geriatric hospitalized patients in internal wards: A double-blind randomized control trial Kojaie-Bidgoli, A. Sharifi, F. Maghsoud, F. Alizadeh-Khoei, M. Jafari, F. Sadeghi, F. BMC Geriatr 2021

Aged
*Delirium/diagnosis/epidemiology/prevention & control
Double-Blind Method
Hospitals
Humans
Incidence
Iran/epidemiology
*Delirium
*Elderly
*Geriatric
*Hospital elder life program
*Patients
*Prevention

The economic cost of delirium: A systematic review and quality assessment Kinchin, I. Mitchell, E. Agar, M. Trépel, D. Alzheimers Dement 2021

Cost-Benefit Analysis/*economics
Delirium/*therapy
Humans
*Quality Assurance, Health Care
*cost
*cost of illness
*delirium
*economic impact
*methodology
*quality assessment
*systematic review

The Risk of Preoperative Central Nervous System-Acting Medications on Delirium Following Hip or Knee Surgery: A Matched Case-Control Study Kassie, G. M. Roughead, E. E. Nguyen, T. A. Pratt, N. L. Kalisch Ellett, L. M. Drug Saf 2021

Preoperative

Central Nervous System

Delirium

Hip or Knee Surgery

Matched Case-Control Study

Association between ankle brachial index and development of postoperative intensive care unit delirium in patients with peripheral arterial disease Kang, J. An, J. H. Jeon, H. J. Park, Y. J. Sci Rep 2021

Aged
Ankle Brachial Index/*methods
Delirium/*complications
Female
Humans
*Intensive Care Units
Leg/blood supply
Male
Peripheral Arterial Disease/physiopathology/*surgery
*Postoperative Care
*Postoperative Complications
Retrospective Studies

Incidence and predictors of delirium on the intensive care unit in patients with acute kidney injury, insight from a retrospective registry Jäckel, M. Aicher, N. Rilinger, J. Bemtgen, X. Widmeier, E. Wengenmayer, T. Duerschmied, D. Biever, P. M. Stachon, P. Bode, C. Staudacher, D. L. Sci Rep 2021

Acute Kidney Injury/*diagnosis/epidemiology
Aged
Aged, 80 and over
Delirium/*diagnosis/epidemiology
Female
Germany/epidemiology
Hospital Mortality
Humans
Incidence
Intensive Care Units/*statistics & numerical data
Length of Stay
Male
Middle Aged
Prognosis
Registries/*statistics & numerical data
Respiration, Artificial
Retrospective Studies
Risk Factors

Advantages of score-based delirium detection compared to a clinical delirium assessment-a retrospective, monocentric cohort study Jäckel, M. Aicher, N. Bemtgen, X. Rilinger, J. Zotzmann, V. Biever, P. M. Supady, A. Stachon, P. Duerschmied, D. Wengenmayer, T. Bode, C. Staudacher, D. L. PLoS One 2021

score-based delirium detection

clinical delirium

monocentric cohort study

A Comparison of Dexmedetomidine and Propofol on Emergence Delirium in Children Undergoing Cleft Palate Surgery With Sevoflurane-Based Anesthesia Huang, L. Wang, L. Peng, W. Qin, C. J Craniofac Surg 2021

Emergence Delirium

Children

Cleft Palate Surgery

Sevoflurane

Automated machine learning-based model predicts postoperative delirium using readily extractable perioperative collected electronic data Hu, X. Y. Liu, H. Zhao, X. Sun, X. Zhou, J. Gao, X. Guan, H. L. Zhou, Y. Zhao, Q. Han, Y. Cao, J. L. CNS Neurosci Ther 2021

delirium
machine learning
model prediction
nomogram
postoperative

Feasibility of low-dose dexmedetomidine for prevention of postoperative delirium after intracranial operations: a pilot randomized controlled trial He, X. Cheng, K. M. Duan, Y. Q. Xu, S. S. Gao, H. R. Miao, M. Y. Li, H. L. Chen, K. Yang, Y. L. Zhang, L. Gu, H. Q. Zhou, J. X. BMC Neurol 2021

Delirium
Dexmedetomidine
Intracranial operation
Postoperative
Prevention

Reliability and validity of the Japanese version of the 4A's Test for delirium screening in the elderly patient Hasegawa, T. Seo, T. Kubota, Y. Sudo, T. Yokota, K. Miyazaki, N. Muranaka, A. Hirano, S. Yamauchi, A. Nagashima, K. Iyo, M. Sakai, I. Asian J Psychiatr 2021

Attention
Delirium
Reliability and validity
Screening tool
World backwards

Neural autoantibodies in delirium Hansen, N. Krasiuk, I. Titsch, T. J Autoimmun 2021

Cognitive dysfunction
Delirium
Neural autoantibody
Postoperative delirium

Risk Factors for Delirium in the Palliative Care Population: A Systematic Review and Meta-Analysis Guo, D. Lin, T. Deng, C. Zheng, Y. Gao, L. Yue, J. Front Psychiatry 2021

delirium
meta-analysis
palliative care
risk factors
systematic revie

Incidence, risk factors, and consequences of emergence delirium after elective brain tumor resection Gu, W. J. Zhou, J. X. Ji, R. Q. Zhou, L. Y. Wang, C. M. Surgeon 2021

Emergence delirium
Neurosurgery
Outcomes
Risk factors

A scientometric study of publications on delirium from 2001 to 2020 Grover, S. Gupta, B. M Asian J Psychiatr 2021

Aged
*Bibliometrics
Databases, Factual
*Delirium
Humans
Ireland
Publications
United States
Bibliometrics
Delirium
Scientometrics

The neuropsychological profile of delirium vulnerability: A systematic review and meta-analysis Ghezzi, E. S. Ross, T. J. Sharman, R. Davis, D. Boord, M. S. Thanabalan, T. Thomas, J. Keage, H. A. D. Neurosci Biobehav Rev 2021

ageing
attention
brain
cognition
cognitive domains
delirium
intra-subject variability
meta-analysis
neuropsychology
risk prediction
systematic review

Cognitive Functionality of Patients with Delirium after Stroke Dostović, Z. Ibrahimagić, OĆ Smajlović, D. Kunić, S. Čustović, A. Psychiatr Danub 2021

Cognition
*Delirium/epidemiology
Humans
Neuropsychological Tests
Prospective Studies
*Stroke/complications

Sleep quality and emergence delirium in children undergoing strabismus surgery: a comparison between preschool- and school-age patients Do, W. Kim, H. S. Kim, S. H. Kang, H. Lee, D. Baik, J. Lee, H. J. Hong, J. M. BMC Anesthesiol 2021

*Emergence delirium
*Pediatrics
*Preoperative sleep quality
*Strabismus surgery

Multicomponent nursing program to prevent delirium in critically ill patients: a randomized clinical trial Contreras, C. C. T. Esteban, A. N. P. Parra, M. D. Romero, M. K. R. Silva, C. G. D. Buitrago, N. P. D. Rev Gaucha Enferm 2021

*Critical Illness
*Delirium/prevention & control
Humans
Incidence
Intensive Care Units