Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
COVID-19 severity and age increase the odds of delirium in hospitalized adults with confirmed SARS-CoV-2 infection: a cohort study
Authors
LaHue, S. C. Escueta, D. P. Guterman, E. L. Patel, K. Harrison, K. L. Boscardin, W. J. Douglas, V. C. Newman, J. C.
Year
2022
Journal
BMC Psychiatry
Abstract

BACKGROUND: Despite recognition of the neurologic and psychiatric complications associated with SARS-CoV-2 infection, the relationship between coronavirus disease 19 (COVID-19) severity on hospital admission and delirium in hospitalized patients is poorly understood. This study sought to measure the association between COVID-19 severity and presence of delirium in both intensive care unit (ICU) and acute care patients by leveraging an existing hospital-wide systematic delirium screening protocol. The secondary analyses included measuring the association between age and presence of delirium, as well as the association between delirium and safety attendant use, restraint use, discharge home, and length of stay. METHODS: In this single center retrospective cohort study, we obtained electronic medical record (EMR) data using the institutional Epic Clarity database to identify all adults diagnosed with COVID-19 and hospitalized for at least 48-h from February 1-July 15, 2020. COVID-19 severity was classified into four groups. These EMR data include twice-daily delirium screenings of all patients using the Nursing Delirium Screening Scale (non-ICU) or CAM-ICU (ICU) per existing hospital-wide protocols. RESULTS: A total of 99 patients were diagnosed with COVID-19, of whom 44 patients required ICU care and 17 met criteria for severe disease within 24-h of admission. Forty-three patients (43%) met criteria for delirium at any point in their hospitalization. Of patients with delirium, 24 (56%) were 65 years old or younger. After adjustment, patients meeting criteria for the two highest COVID-19 severity groups within 24-h of admission had 7.2 times the odds of having delirium compared to those in the lowest category [adjusted odds ratio (aOR) 7.2; 95% confidence interval (CI) 1.9, 27.4; P = 0.003]. Patients > 65 years old had increased odds of delirium compared to those < 45 years old (aOR 8.7; 95% CI 2.2, 33.5; P = 0.003). Delirium was associated with increased odds of safety attendant use (aOR 4.5; 95% CI 1.0, 20.7; P = 0.050), decreased odds of discharge home (aOR 0.2; 95% CI 0.06, 0.6; P = 0.005), and increased length of stay (aOR 7.5; 95% CI 2.0, 13; P = 0.008). CONCLUSIONS: While delirium is common in hospitalized patients of all ages with COVID-19, it is especially common in those with severe disease on hospital admission and those who are older. Patients with COVID-19 and delirium, compared to COVID-19 without delirium, are more likely to require safety attendants during hospitalization, less likely to be discharged home, and have a longer length of stay. Individuals with COVID-19, including younger patients, represent an important population to target for delirium screening and management as delirium is associated with important differences in both clinical care and disposition.

PMID

PMC8883244

Keywords

Adult
Aged
*COVID-19/complications
Cohort Studies
*Delirium/diagnosis/etiology
Hospitalization
Humans
Intensive Care Units
Middle Aged
Retrospective Studies
SARS-CoV-2
*covid-19
*Delirium
*Encephalopathy
*Hospital discharge
*Hospitalization
*Patient outcomes
*Restraints
*Safety attendants

Page(s)
151
Issue
1

Search:
Total Records Found: 6272, showing 100 per page
TitleAuthorsJournalYearKeywords
Brain Network Dysfunction in Poststroke Delirium and Spatial Neglect: An fMRI Study Boukrina, O. Kowalczyk, M. Koush, Y. Kong, Y. Barrett, A. M. Stroke 2022

Adult
Aged
Aged, 80 and over
Brain/*diagnostic imaging
Brain Mapping
Delirium/*diagnostic imaging/etiology
Female
Functional Laterality/physiology
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Nerve Net/*diagnostic imaging
Perceptual Disorders/*diagnostic imaging/etiology
Stroke/complications/*diagnostic imaging
*MRI, functional
*attention
*basal ganglia
*delirium
*incidence
*ischemic stroke
*prevalence

Postoperative delirium prediction using machine learning models and preoperative electronic health record data Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. BMC Anesthesiol 2022

Aged
Cohort Studies
Delirium/*diagnosis
Electronic Health Records/*statistics & numerical data
Female
Humans
*Machine Learning
Male
Middle Aged
Postoperative Complications/*diagnosis
Predictive Value of Tests
Preoperative Period
Reproducibility of Results
Retrospective Studies
*Delirium prevention
*Geriatric surgery
*Postoperative delirium
*Risk prediction model
improve healthcare quality interventions. 2.AJB is a co-founder and consultant to
Personalis and NuMedii
consultant to Samsung, Mango Tree Corporation, and in the
recent past, 10x Genomics, Helix, Pathway Genomics, and Verinata (Illumina)
has
served on paid advisory panels or boards for Geisinger Health, Regenstrief
Institute, Gerson Lehman Group, AlphaSights, Covance, Novartis, Genentech, and
Merck, and Roche
is a shareholder in Personalis and NuMedii
is a minor shareholder
in Apple, Facebook, Alphabet (Google), Microsoft, Amazon, Snap, 10x Genomics,
Illumina, CVS, Nuna Health, Assay Depot, Vet24seven, Regeneron, Sanofi, Royalty
Pharma, AstraZeneca, Moderna, Biogen, and Sutro, and several other non-health
related companies and mutual funds
and has received honoraria and travel
reimbursement for invited talks from Johnson and Johnson, Roche, Genentech, Pfizer,
Merck, Lilly, Takeda, Varian, Mars, Siemens, Optum, Abbott, Celgene, AstraZeneca,
AbbVie, Westat, and many academic institutions, medical or disease specific
foundations and associations, and health systems. Atul Butte receives royalty
payments through Stanford University, for several patents and other disclosures
licensed to NuMedii and Personalis. Atul Butte’s research has been funded by NIH,
Northrup Grumman (as the prime on an NIH contract), Genentech, Johnson and Johnson,
FDA, Robert Wood Johnson Foundation, Leon Lowenstein Foundation, Intervalien
Foundation, Priscilla Chan and Mark Zuckerberg, the Barbara and Gerson Bakar
Foundation, and in the recent past, the March of Dimes, Juvenile Diabetes Research
Foundation, California Governor’s Office of Planning and Research, California
Institute for Regenerative Medicine, L’Oreal, and Progenity. 3.The above
organizations had no direct involvement in study design
in the collection,
analysis, and interpretation of data
in the writing of the report
or in the
decision to submit the article for publication. 4.The remainder of authors declare
no conflicts of interest.

High-dose preoperative glucocorticoid for prevention of emergence and postoperative delirium in liver resection: A double-blinded randomized clinical trial substudy Awada, H. N. Steinthorsdottir, K. J. Schultz, N. A. Hillingsø, J. G. Larsen, P. N. Jans, Ø Kehlet, H. Aasvang, E. K. Acta Anaesthesiol Scand 2022

emergence
liver resection
postoperative delirium
preoperative glucocorticoid

Grip strength as a predictor of postoperative delirium in patients with colorectal cancers Arita, A. Takahashi, H. Ogino, T. Miyoshi, N. Uemura, M. Akasaka, H. Sugimoto, K. Rakugi, H. Doki, Y. Eguchi, H. Ann Gastroenterol Surg 2022

colorectal cancer
grip strength
postoperative delirium

Positive scores on the 4AT delirium assessment tool at hospital admission are linked to mortality, length of stay and home time: two-centre study of 82,770 emergency admissions Anand, A. Cheng, M. Ibitoye, T. Maclullich, A. M. J. Vardy, Erlc Age Ageing 2022

4 ‘A’s Test (4AT)
delirium
dementia
emergency department (ED)
geriatrics
hospitalisation
older people

Barriers to completing the 4AT for delirium and its clinical implementation in two hospitals: a mixed-methods study Alhaidari, A. A. O. Matsis, K. P. Eur Geriatr Med 2022

Aged
*Delirium/diagnosis/epidemiology/therapy
Female
Hospitalization
Hospitals
Humans
Male
Retrospective Studies
*Delirium
*Guideline adherence
*Hospitals
*Implementation science
*New Zealand

The quality of palliative sedation in end-stage disease: audit from a department of oncology and haematology Alessia, S. Matilde, S. F. Chrystel, I. Massimiliano, S. Daniele, D. Claudia, F. Raffaella, P. Flavia, C. Leonardo, F. Chiara, C. Leonardo, P. Massimo, D. Mario, L. Giuseppe, L. Support Care Cancer 2022

Conscious Sedation/methods
*Deep Sedation/methods
*Hematology
Humans
Hypnotics and Sedatives/therapeutic use
Medical Oncology
Midazolam
*Neoplasms/therapy
Palliative Care/methods
*Terminal Care/methods
D-PaP score
End-stage disease
Palliative sedation
Refractory symptoms
Rudkin score

Delirium risk in geriatric hip hemi-arthroplasty (DRIGHA): Development and validation of a novel score using a national data Ahmed, N. Kuo, Y. H. Injury 2022

Aged
*Delirium/epidemiology/etiology/prevention & control
*Hemiarthroplasty/adverse effects
*Hip Fractures
Humans
Incidence
Male
Postoperative Complications/epidemiology/surgery
Risk Factors
Delirium
Geriatric
Hemiarthroplasty
Hip fracture

Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. Int Psychogeriatr 2022

Alzheimer’s disease
biomarkers
delirium
inflammation
postoperative delirium

The association between midazolam premedication and postoperative delirium - a retrospective cohort study Zarour, S. Weiss, Y. Kiselevich, Y. Iacubovici, L. Karol, D. Shaylor, R. Davydov, T. Matot, I. Cohen, B. J Clin Anesth 2023

Anesthesia, Elderly, Midazolam, Postoperative delirium

Effects of perioperative intravenous glucocorticoids on perioperative neurocognitive disorders in adults after surgery: A PRISMA-compliant meta-analysis of randomized controlled trials Wang, F. Hao, X. Zhu, Y. Medicine (Baltimore) 2023

Humans, Adult, Adolescent, *Glucocorticoids, Randomized Controlled Trials as Topic, Administration, Intravenous, *Hip Fractures, Neurocognitive Disorders

Association between emergency department modifiable risk factors and subsequent delirium among hospitalized older adults Oliveira, J. E. Silva L. Stanich, J. A. Jeffery, M. M. Lindroth, H. L. Miller, D. M. Campbell, R. L. Rabinstein, A. A. Pignolo, R. J. Bellolio, F. Am J Emerg Med 2022

Acute brain failure
Delirium
Geriatric emergency medicine
Geriatrics
Older adults

Practices in sedation, analgesia, mobilization, delirium, and sleep deprivation in adult intensive care units (SAMDS-ICU): an international survey before and during the COVID-19 pandemic Luz, M. Brandão Barreto, B. de Castro, R. E. V. Salluh, J. Dal-Pizzol, F. Araujo, C. De Jong, A. Chanques, G. Myatra, S. N. Tobar, E. Gimenez-Esparza Vich, C. Carini, F. Ely, E. W. Stollings, J. L. Drumright, K. Kress, J. Povoa, P. Shehabi, Y. Mphandi, W Ann Intensive Care 2022

Analgesia
Covid-19
Delirium
Mobilization
Sedation
Sleep deprivation

Mental capacity legislation and communication disability: A cross-sectional survey exploring the impact of the COVID-19 pandemic on the provision of specialist decision-making support by UK SLTs Jayes, M. Borrett, S. Bose, A. Int J Lang Commun Disord 2022

Adult
*covid-19
*Communication Disorders/epidemiology/therapy
Cross-Sectional Studies
Humans
Language Therapy
Pandemics
SARS-CoV-2
Speech Therapy
United Kingdom
*COVID-19, decision-making, disability, mental capacity, speech and language
therapists
*adults

Delirium and Associated Factors in a Cohort of Hospitalized Patients With Coronavirus Disease 2019 García-Grimshaw, M. Chiquete, E. Jiménez-Ruiz, A. Vidal-Mayo, J. J. Grajeda-González, S. L. Vargas-Martínez, MlÁ Toapanta-Yanchapaxi, L. N. Valdés-Ferrer, S. I. Chávez-Martínez, O. A. Marché-Fernández, O. A. Jiménez-Ávila, A. I. Cantú-Brito, J Acad Consult Liaison Psychiatry 2022

Adult
*covid-19
*Delirium/epidemiology
Female
Humans
Male
Middle Aged
Pandemics
Retrospective Studies
SARS-CoV-2
*SARS-CoV-2
*cohort study
*coronavirus
*delirium
*hospitalization

Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends in 2011-2018 Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. J Acad Consult Liaison Psychiatry 2022

Dsm
Icd
delirium
encephalopathy

Effectiveness of combined non-pharmacological interventions in the prevention of delirium in critically ill patients: A randomized clinical trial Faustino, T. N. Suzart, N. A. Rabelo, Rnds Santos, J. L. Batista, G. S. Freitas, Y. S. Saback, D. A. Sales, Nmmd Brandao Barreto, B. Gusmao-Flores, D. J Crit Care 2022

Critical Care
Delirium prevention
Intensive Care Unit
Non-pharmacological interventions
Randomized controlled trial
interests.

Combined cerebral and somatic near-infrared spectroscopy oximetry monitoring during liver surgery: an observational and non-interventional study Collin, Y. Hu, T. Denault, A. Fortier, A. Beaubien-Souligny, W. Lapointe, R. Vandenbroucke-Menu, F. Korean J Anesthesiol 2022

Hepatectomy
Intraoperative
Liver
Monitoring
Oximetry
Saturation

Characteristics and Outcome Determinants of Hospitalized Older Patients with Cognitive Dysfunction Chao, Y. T. Kuo, F. H. Lee, Y. S. Huang, Y. H. Weng, S. C. Chou, Y. Y. Lin, C. S. Lin, S. Y. Int J Environ Res Public Health 2022

Activities of Daily Living
Aged
*Cognition Disorders/epidemiology
*Cognitive Dysfunction/epidemiology
Hospitalization
Humans
Inpatients
*activity of daily living
*cognitive impairment
*dementia
*geriatric assessment
*length of stay
*readmission

Delirium in hospitalized patients with COVID-19 pneumonia: a prospective, cross-sectional, cohort study Callea, A. Conti, G. Fossati, B. Carassale, L. Zagaria, M. Caporotundo, S. Ziglioli, E. Brunetti, V. Della Marca, G. Rollo, E. Intern Emerg Med 2022

Covid-19
Comfortable care
Delirium
Frailty
Helmet-CPAP

Association of perioperative midazolam use and complications: a population-based analysis Athanassoglou, V. Cozowicz, C. Zhong, H. Illescas, A. Poeran, J. Liu, J. Poultsides, L. Memtsoudis, S. G. Reg Anesth Pain Med 2022

analgesia
anesthesia
conduction
epidemiology

Best practices to prevent delirium in hospitalised patients Yerra, S. Yarra, P. Evid Based Nurs 2022

*Delirium/prevention & control
Humans
Intensive Care Units
*adult intensive & critical care
*delirium & cognitive disorders
*nursing
*protocols & guidelines

Inhalational Versus Propofol-based Intravenous Maintenance of Anesthesia for Emergence Delirium in Adults: A Meta-analysis and Trial Sequential Analysis Yang, Y. Feng, L. Ji, C. Lu, K. Chen, Y. Chen, B. J Neurosurg Anesthesiol 2022
Role of interleukin-18 in postoperative delirium: an exploratory analysis Wu, J. G. Taylor, J. Parker, M. Kunkel, D. Rivera, C. Pearce, R. A. Lennertz, R. Sanders, R. D. Br J Anaesth 2022

delirium
inflammation
interleukin-18
postoperative
surgery

Effect of general anesthesia with thoracic paravertebral block on postoperative delirium in elderly patients undergoing thoracoscopic lobectomy: a randomized-controlled trial Wei, W. Zheng, X. Gu, Y. Fu, W. Tang, C. Yao, Y. BMC Anesthesiol 2022

*Postoperative delirium
*Postoperative quality of recovery
*Thoracic paravertebral block
*Video-assisted thoracoscopic lobectomy

Probable Delirium and Associated Patient Characteristics in Long-Term Care and Complex Continuing Care: A Population-Based Observational Study Webber, C. Watt, C. L. Bush, S. H. Lawlor, P. G. Knoefel, F. Momoli, F. Thavorn, K. Casey, G. Tanuseputro, P. J Am Med Dir Assoc 2022

Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
Humans
*Long-Term Care
Ontario/epidemiology
Prevalence
*Delirium
*complex continuing care
*continuing care
*prevalence
*risk factors

Postoperative delirium and its relationship with biomarkers for dementia: a meta-analysis Wang, S. Greene, R. Song, Y. Chan, C. Lindroth, H. Khan, S. Rios, G. Sanders, R. D. Khan, B. Int Psychogeriatr 2022

Alzheimer’s disease
biomarkers
delirium
inflammation
postoperative delirium

Melatonin and melatonergic agents for the prevention of postoperative delirium: A meta-analysis of randomized placebo-controlled trials Wang, C. M. Zhou, L. Y. Asian J Surg 2022

Adult
Aged
Anesthesia, General
*Delirium/prevention & control
Humans
Incidence
*Melatonin/therapeutic use
Randomized Controlled Trials as Topic
Delirium
Melatonin
Meta-analysis

Dexmedetomidine for prevention of postoperative delirium in older adults undergoing oesophagectomy with total intravenous anaesthesia Valent, A. Carval, A. Cattan, P. Plaud, B. Eur J Anaesthesiol 2022

Aged
Anesthesia, General
Anesthesia, Intravenous
*Delirium/chemically induced/diagnosis/prevention & control
*Dexmedetomidine/adverse effects
Esophagectomy/adverse effects
Humans

Transfusion-Associated Delirium in Children: No Difference Between Short Storage Versus Standard Issue RBCs Traube, C. Tucci, M. Nellis, M. E. Avery, K. L. McQuillen, P. S. Fitzgerald, J. C. Muszynski, J. A. Cholette, J. M. Schwarz, A. J. Stalets, E. L. Quaid, M. A. Hanson, S. J. Lacroix, J. Reeder, R. W. Spinella, P. C. Crit Care Med 2022
Pediatric Delirium: We Have Come a Long Way, and We Have Only Just Begun Traube, C. Crit Care Med 2022
Beware the Aftermath: Delirium and Post-Intensive Care Syndrome in Critically Ill Children Traube, C. Pediatr Crit Care Med 2022
Amyloid deposition on positron emission tomography correlates with severity of perioperative delirium: a case-control pilot study Torres-Velázquez, M. Parker, M. Bo, A. White, M. Tanabe, S. Pearce, R. A. Lennertz, R. Cho, S. Y. Bendlin, B. Johnson, S. C. Prabhakaran, V. McMillan, A. B. Sanders, R. D. Br J Anaesth 2022

amyloid
delirium
neurodegeneration
positron emission tomography
postoperative complications
surgery

VE-CAM-S: Visual EEG-Based Grading of Delirium Severity and Associations With Clinical Outcomes Tesh, R. A. Sun, H. Jing, J. Westmeijer, M. Neelagiri, A. Rajan, S. Krishnamurthy, P. V. Sikka, P. Quadri, S. A. Leone, M. J. Paixao, L. Panneerselvam, E. Eckhardt, C. Struck, A. F. Kaplan, P. W. Akeju, O. Jones, D. Kimchi, E. Y. Westover, M. B. Crit Care Explor 2022

Eeg
delirium
delirium severity
encephalopathy
prognosis

KIBRA, MTNR1B, and FKBP5 genotypes are associated with decreased odds of incident delirium in elderly post-surgical patients Terrelonge, M. LaHue, S. C. Tang, C. Movsesyan, I. Pullinger, C. R. Dubal, D. B. Leung, J. Douglas, V. C. Sci Rep 2022
Pilot Study of Lemborexant for Insomnia in Cancer Patients with Delirium Terada, T. Hirayama, T. Sadahiro, R. Wada, S. Nakahara, R. Matsuoka, H. J Palliat Med 2022

cancer patients
delirium
insomnia
lemborexant
orexin receptor antagonist

Managing agitation secondary to hyperactive delirium in deteriorating patients Teece, A. Nurs Stand 2022

*Delirium/etiology
Humans
Intensive Care Units
Length of Stay
Psychomotor Agitation
Restraint, Physical
*agitation
*clinical
*control and restraint
*critical care
*delirium
*intensive care
*mental health
*nursing care
*professional
*signs and symptoms
*symptom management

Incidence of Delirium With Different Oral Opioids in Previously Opioid-Naive Patients Sugiyama, Y. Tanaka, R. Sato, T. Sato, T. Saitoh, A. Yamada, D. Shino, M. Am J Hosp Palliat Care 2022

concomitant drugs
delirium
morphine
oral opioids
oxycodone
tapentadol

Adult behavior toward the child before surgery and pediatric emergence delirium Sobol, M. Sobol, M. K. Kowal, M. Paediatr Anaesth 2022

Adult
Anesthesia Recovery Period
Anesthesia, General
Child
*Emergence Delirium/epidemiology
Humans
Campis-r
behavior
emergence delirium
surgery

Risk Factors for Delirium and Association of Antipsychotic Use with Delirium Progression in Critically Ill Trauma Patients Shoulders, B. R. Elsabagh, S. Tam, D. J. Frantz, A. M. Alexander, K. M. Voils, S. A. Am Surg 2022

antipsychotic
delirium
intensive care unit
risk factors
trauma

Incidence and Risk Factors of Ventilator-Associated Pneumonia among Patients with Delirium in the Intensive Care Unit: A Prospective Observational Study Shamsizadeh, M. Fathi Jouzdani, A. Rahimi-Bashar, F. Crit Care Res Pract 2022
Delirium in older adults, if you think it's the urine, think again Schonnop, R. Woods, R. Ellis, B. Cjem 2022
The detection of delirium in admitted oncology patients: a scoping review Sands, M. B. Wee, I. Agar, M. Vardy, J. L. Eur Geriatr Med 2022

Cancer
Delirium
Detection
Inpatient
Oncology
Screening

Delirium in the Context of Zonisamide-Induced Toxic Epidermal Necrolysis Reinfeld, S. Tejeda, C. I. Koola, M. M. Prim Care Companion CNS Disord 2022
Prevalence of Delirium in End-of-life Palliative Care Patients: An Observational Study Recchia, A. Rizzi, B. Favero, A. Nobili, A. Pasina, L. Med Princ Pract 2022
Hospitalizations of older people in an emergency department related to potential medication-induced hyperactive delirium: a cross-sectional study Raso, J. Santos, L. M. C. Reis, D. A. Frangiotti, M. A. C. Zanetti, A. C. B. Capucho, H. C. Herdeiro, M. T. Roque, F. Pereira, L. R. L. Varallo, F. R. Int J Clin Pharm 2022

Aged
Delirium
Drug therapy
Emergency service, hospital
Risk factors

Clinical Significance of Delirium With Catatonic Signs in Patients With Neurological Disorders Ramirez-Bermudez, J. Medina-Gutierrez, A. Gomez-Cianca, H. Arias, P. Pérez-Gonzalez, A. Lebrija-Reyes, P. A. Espinola-Nadurille, M. Aguilar-Venegas, L. C. Ojeda-López, C. Restrepo-Martínez, M. Bayliss, L. Juárez-Jaramillo, C. A. Peñaloza, G. Rivas-Al J Neuropsychiatry Clin Neurosci 2022

Catatonia
Delirium

Patient perspectives on delirium and cognitive dysfunction after surgery: a cross-sectional survey Ragheb, J. Khatibi, N. McKinney, A. Brooks, J. Hill-Carruthers, M. Vlisides, P. E. Br J Anaesth 2022

cognitive dysfunction
delirium
neurocognitive disorders
patient participation
survey

Association between delirium and cognitive impairment: there is a link? Pistacchi, M. Gioulis, M. Marsala, S. Z. Curr Alzheimer Res 2022

Cognitive Impairment
Delirium Subtype
Dementia Screening
Population
encephalopathy
neurodegenerative diseases

Utility of white matter disease and atrophy on routinely acquired brain imaging for prediction of long-term delirium risk: population-based cohort study Pendlebury, S. T. Thomson, R. J. Welch, S. J. V. Kuker, W. Rothwell, P. M. Age Ageing 2022

Atrophy/pathology
Brain/diagnostic imaging/pathology
Cohort Studies
*Delirium/diagnostic imaging/epidemiology
Humans
*Ischemic Attack, Transient/pathology
*Leukoencephalopathies/pathology
Magnetic Resonance Imaging
Neuroimaging
*Stroke
*White Matter/diagnostic imaging/pathology
*brain imaging
*delirium
*older people
*transient ischemic attack (TIA)

Massachusetts Intensive Care Unit Nurses From Multiple Hospitals Develop a Collaborative to Improve Delirium Assessment Accuracy O'Donoghue, S. C. Meyers, K. Manning, C. R. Pellegrino, L. S. Ryan, C. P. Crowell, A. M. Nolan, L. M. Gallagher, G. E. Dimens Crit Care Nurs 2022

Critical Care
*Delirium/diagnosis
Hospitals
Humans
Intensive Care Units
*Nurses

Incidence and factors associated with postoperative delirium in patients undergoing transurethral resection of bladder tumor Nakatani, S. Ida, M. Wang, X. Naito, Y. Kawaguchi, M. JA Clin Rep 2022

Age
Body mass index
General anesthesia
Postoperative delirium
Tur-bt

Association of Nutritional Status with New-Onset Delirium in Elderly, Acute Care, Orthopaedic Trauma Patients: A Single-Center Observational Study Maher, S. S. Franco-Garcia, E. Zhou, C. Heng, M. van Pelt, M. Akeju, O. Quraishi, S. A. J Orthop Trauma 2022

Aged
Cross-Sectional Studies
*Delirium/diagnosis/epidemiology
Geriatric Assessment
Humans
*Malnutrition
Nutritional Status
*Orthopedics
Retrospective Studies

Efficacy of EWINDOW for prevention of delirium at intensive care units: A protocol for systematic review and meta-analysis Liu, J. Wang, J. Medicine (Baltimore 2022

delirium, EWINDOW, intensive care units

Delirium and subsyndromal delirium are associated with the long-term risk of death after ischaemic stroke Klimiec-Moskal, E. Slowik, A. Dziedzic, T. Aging Clin Exp Res 2022

Delirium
Mortality
Stroke
Subsyndromal delirium

An innovative post-hospital model of care (DDEFY Delirium): A pilot randomized trial Khan, A. Uribe-Cano, D. Klumph, M. Simpson, M. Macias Tejada, J. Galambos, C. Hubatch, S. Malone, M. L. J Am Geriatr Soc 2022
Impact of postanesthesia care unit delirium on self-reported cognitive function and perceived health status: a prospective observational cohort study Kainz, E. Stuff, K. Kahl, U. Wiessner, C. Yu, Y. von Breunig, F. Nitzschke, R. Haese, A. Graefen, M. Fischer, M. Qual Life Res 2022

Anesthesia recovery period
Cognitive dysfunction
Delirium
Perceived health status
Postoperative cognitive complications
Prostatectomy
Quality of life

Can multifaceted educational intervention improve clinical practice and patient outcomes regarding delirium in nursing homes? Jeong, E. Chang, S. O Jpn J Nurs Sci 2022

Aged
*Delirium/diagnosis
Health Personnel
Humans
Nursing Homes
*Nursing Staff, Hospital
delirium
intervention

Does Preoperative Cognitive Optimization Improve Postoperative Outcomes in the Elderly? Ishizawa, Y. J Clin Med 2022

advanced age
cognitive training
perioperative neurocognitive disorder
postoperative delirium
preoperative optimization

Postoperative Delirium in Lung Cancer Anatomical Resection-Analysis of Risk Factors and Prognosis Ishibashi, H. Wakejima, R. Asakawa, A. Sugita, Y. Ishikawa, Y. Hanafusa, M. Baba, S. Nakashima, Y. Seto, K. Okubo, K. World J Surg 2022
Preoperative Risk Factors and Early Outcomes of Delirium in Valvular Open-Heart Surgery Hulde, N. Zittermann, A. Tigges-Limmer, K. Koster, A. Weinrautner, N. Gummert, J. von Dossow, V. Thorac Cardiovasc Surg 2022
Plasma 5-HIAA activity indicative of serotonergic disturbances in cognitively impaired, elderly patients experiencing postoperative delirium Heylen, A. Vermeiren, Y. De Rooij, S. E. Scholtens, R. M. Van Munster, B. C. Van Dam, D. De Deyn, P. P. Int J Geriatr Psychiatry 2022

Aged
Cognition
*Delirium
Humans
Hydroxyindoleacetic Acid
*hplc
*uplc
*ageing
*biogenic amines
*biomarker
*cognitive impairment
*monoamine neurotransmitters

Depression, Delirium and Post-Intensive Care Syndrome Garcez-Leme, L. E. Avelino-Silva, T. J. Int Psychogeriatr 2022
Usefulness of Preoperative Controlling Nutritional Status in Predicting Prolonged Hospitalization and Incidence of Postoperative Delirium for Elderly Hepatectomy with Hepatocellular Carcinoma Fujio, A. Usuda, M. Hara, Y. Kakizaki, Y. Okada, K. Miyata, G. Unno, M. Kamei, T. Tohoku J Exp Med 2022

Aged
*Carcinoma, Hepatocellular/epidemiology/surgery
*Delirium/epidemiology
Hepatectomy/adverse effects
Hospitalization
Humans
Incidence
*Liver Neoplasms/epidemiology/surgery
Nutritional Status
Postoperative Complications/epidemiology
Prognosis
Retrospective Studies
controlling nutritional status
delirium
elderly patients
hepatectomy
hepatocellular carcinoma

Inpatient Diagnosis of Delirium and Encephalopathy: Coding Trends 2011-2018 Franks, J. A. Anderson, J. L. Bowman, E. Li, C. Y. Kennedy, R. E. Yun, H. J Acad Consult Liaison Psychiatry 2022

Dsm
Icd
delirium
encephalopathy

Barriers and facilitators to nursing delirium screening in older emergency patients: a qualitative study using the theoretical domains framework Eagles, D. Cheung, W. J. Avlijas, T. Yadav, K. Ohle, R. Taljaard, M. Molnar, F. Stiell, I. G. Age Ageing 2022

Aged
*Delirium/diagnosis
*Emergency Service, Hospital
Humans
Mass Screening
Qualitative Research
*delirium
*emergency department
*older people
*qualitative study
*screening

The evidence for introducing case-finding for delirium and dementia in older medical inpatients in a New Zealand hospital Cullum, S. Kubba, Y. Varghese, C. Coomarasamy, C. Hopkins, J. Australas Psychiatry 2022

case-finding
delirium
dementia
general hospital
screening

Pediatric delirium in times of COVID-19 Castro, R. E. V. Rodríguez-Rubio, M. Magalhães-Barbosa, M. C. Prata-Barbosa, A. Rev Bras Ter Intensiva 2022

*covid-19
Child
*Delirium/diagnosis
Humans
SARS-CoV-2

Accuracy of delirium risk factors in adult intensive care unit patients Carvalho, L. A. C. Correia, M. D. L. Ferreira, R. C. Botelho, M. L. Ribeiro, E. Duran, E. C. M. Rev Esc Enferm USP 2022

Adult
*Delirium/diagnosis/epidemiology
Hospitalization
Humans
Intensive Care Units
Male
Prospective Studies
Risk Factors

The management of delirium in the older adult in advanced nursing practice Carey, E. Furlong, E. Smith, R. Br J Nurs 2022

*Advanced Practice Nursing
Aged
*Delirium/diagnosis
Humans
*Nursing Care
Advanced nursing practice
Delirium
Differential diagnosis
Older adult
Older person

Postoperative Delirium: The Search for Effective Interventions Campbell, D. Short, T. G. Chan, M. T. V. J Neurosurg Anesthesiol 2022
Confusion and Representative Restraint: An Exercise in Clinical Reasoning Bushunow, V. Klein, A. Follansbee, W. Bonifacino, E. J Gen Intern Med 2022

*Clinical Reasoning
*Confusion/etiology
Exercise
Humans
Restraint, Physical

Psychoactive medication therapy and delirium screening in skilled nursing facilities Briesacher, B. A. Olivieri-Mui, B. L. Koethe, B. Saczynski, J. S. Fick, D. M. Devlin, J. W. Marcantonio, E. R. J Am Geriatr Soc 2022

delirium
dementia
prescribing
skilled-nursing facilities

Comparison of delirium detection tools in acute care : A rapid review Brefka, S. Eschweiler, G. W. Dallmeier, D. Denkinger, M. Leinert, C. Z Gerontol Geriatr 2022

4As test
Assessment
Confusion assessment method
Practicability
Screening

Implications of the COVID-19 pandemic: Virtual nursing education for delirium care Bourgault, A. Mayerson, E. Nai, M. Orsini-Garry, A. Alexander, I. M. J Prof Nurs 2022

*covid-19
*Delirium
*Education, Nursing
Humans
Pandemics
SARS-CoV-2
*Students, Nursing
Covid-19
Clinical experience
Delirium
Nursing education
Technology
Virtual simulation

Postoperative delirium prediction using machine learning models and preoperative electronic health record data Bishara, A. Chiu, C. Whitlock, E. L. Douglas, V. C. Lee, S. Butte, A. J. Leung, J. M. Donovan, A. L. BMC Anesthesiol 2022

*Delirium prevention
*Geriatric surgery
*Machine learning
*Postoperative delirium
*Risk prediction model

Association between nonpharmacological strategies and delirium in intensive care unit Bersaneti, M. D. R. Whitaker, I. Y. Nurs Crit Care 2022

caregivers
critical care nursing
delirium
intensive care units
physical restraint

Differential Effects of Gamma-Aminobutyric Acidergic Sedatives on Risk of Post-Extubation Delirium in the ICU: A Retrospective Cohort Study From a New England Health Care Network Azimaraghi, O. Wongtangman, K. Wachtendorf, L. J. Santer, P. Rumyantsev, S. Ahn, C. Kiyatkin, M. E. Teja, B. Sarge, T. Subramaniam, B. Eikermann, M. Crit Care Med 2022

Differential Effects

Gamma-Aminobutyric Acidergic Sedatives

Risk

Post-Extubation Delirium

ICU

Retrospective

Cohort

Study

Risk factors for postoperative delirium after cardiac surgical procedures with cardioplegic arrest Andrási, T. B. Talipov, I. Dinges, G. Arndt, C. Rastan, A. J. Eur J Cardiothorac Surg 2022

Cabg
Cpb
Delirium
Probability risk calculator
Valve/aortic surgery

Delirium screening tools in the post-anaesthetic care unit: a systematic review and meta-analysis Aldwikat, R. K. Manias, E. Tomlinson, E. Amin, M. Nicholson, P. Aging Clin Exp Res 2022

Delirium
Delirium diagnosis
Post-anesthetic recovery unit
Screening tools
Sensitivity and specificity

Effect of earplug/eye mask on sleep and delirium in intensive care patients Akpinar, R. B. Aksoy, M. Kant, E. Nurs Crit Care 2022

delirium
earplugs
eye mask
intensive care unit
sleep quality

Inclusion of interleukin-6 improved performance of postoperative delirium prediction for patients undergoing coronary artery bypass graft (POD-CABG): A derivation and validation study Zhang, S. Ji, M. H. Ding, S. Wu, Y. Feng, X. W. Tao, X. J. Liu, W. W. Ma, R. Y. Wu, F. Q. Chen, Y. L. J Cardiol 2021

Coronary artery bypass graft surgery
Interleukin-6
Postoperative delirium
Prediction rule
interest

DNA methylation in the TNF-alpha gene decreases along with aging among delirium inpatients Yamanashi, T. Saito, T. Yu, T. Alario, A. Comp, K. Crutchley, K. J. Sullivan, E. J. Anderson, Z. M. Marra, P. S. Chang, G. Wahba, N. E. Jellison, S. S. Meyer, A. A. Mathur, S. Pandharipande, P. Yoshino, A. Kaneko, K. Lee, S. Toda, H. Iwata, M. Shinozaki, Neurobiol Aging 2021

Aged
Aging/*genetics
Cohort Studies
CpG Islands/genetics
DNA Methylation/*genetics
Delirium/etiology/*genetics
Female
Genome-Wide Association Study/methods
High-Throughput Nucleotide Sequencing
Humans
Inflammation
*Inpatients
Male
Tumor Necrosis Factor-alpha/*genetics
*Aging
*DNA methylation
*Delirium
*EPIC array
*Pyrosequencing
*TNF-alpha

DNA methylation in the inflammatory genes after neurosurgery and diagnostic ability of post-operative delirium Yamanashi, T. Nagao, T. Wahba, N. E. Marra, P. S. Crutchley, K. J. Meyer, A. A. Andreasen, A. J. Hellman, M. M. Jellison, S. S. Hughes, C. G. Pandharipande, P. P. Howard Iii, M. A. Kawasaki, H. Iwata, M. Hefti, M. M. Shinozaki, G. Transl Psychiatry 2021

Epigenetics and behaviour, Molecular neuroscience

Intraoperative hypotension and delirium among older adults undergoing transcatheter aortic valve replacement Wesselink, E. M. Abawi, M. Kooistra, N. H. M. Kappen, T. H. Agostoni, P. Emmelot-Vonk, M. Pasma, W. van Klei, W. A. van Jaarsveld, R. C. van Dongen, C. S. Doevendans, Pafm Slooter, A. J. C. Stella, P. R. J Am Geriatr Soc 2021

Aged, 80 and over
Anesthesia, General/*adverse effects
Delirium/*epidemiology
Female
Humans
Hypotension/*etiology
Intraoperative Complications/*chemically induced
Male
Netherlands
Postoperative Complications/*chemically induced
Retrospective Studies
Risk Factors
Transcatheter Aortic Valve Replacement/*adverse effects
Treatment Outcome
*tavr
*delirium
*intraoperative hypotension
*transcatheter aortic valve replacement

Patterns of Delirium in a Pediatric Intensive Care Unit and Associations With Noise Pollution Weatherhead, J. R. Niedner, M. Dahmer, M. K. Malas, N. Owens, T. Kawai, Y. J Intensive Care Med 2021

delirium
noise pollution
patient safety
pediatric intensive care unit
quality improvement
sleep

Gender Differences and Postoperative Delirium in Adult Patients Undergoing Cardiac Valve Surgery Wang, H. Guo, X. Zhu, X. Li, Y. Jia, Y. Zhang, Z. Yuan, S. Yan, F. Front Cardiovasc Med 2021

adult
cardiac surgery
gender
postoperative delirium
risk factor

Comparison of restrictive fluid therapy with goal-directed fluid therapy for postoperative delirium in patients undergoing spine surgery: a randomized controlled trial Wang, D. D. Li, Y. Hu, X. W. Zhang, M. C. Xu, X. M. Tang, J. Perioper Med (Lond) 2021

Goal-directed fluid therapy
Postoperative delirium
Restrictive fluid therapy
Spinal surgery
manuscript.

Effect of dexmedetomidine on postoperative delirium in patients undergoing brain tumour resections: study protocol of a randomised controlled trial Wang, D. Li, R. Li, S. Wang, J. Zeng, M. Dong, J. Liu, X. Lin, N. Peng, Y. BMJ Open 2021

*Brain Neoplasms
Craniotomy/adverse effects
*Delirium/epidemiology/etiology/prevention & control
*Dexmedetomidine/therapeutic use
Double-Blind Method
Humans
Prospective Studies
Randomized Controlled Trials as Topic
*delirium & cognitive disorders
*head & neck tumours
*neurosurgery

Association of preoperative frailty with postoperative delirium after elective brain tumor resection: Retrospective analysis of a prospective cohort Wang, C. M. Ma, Y. L. Yang, X. Y. Ji, R. Q. Gu, W. J. Zhou, J. X. Surgery 2021

Adult
Aged
Brain Neoplasms/complications/economics/*surgery
Craniotomy/*adverse effects
Elective Surgical Procedures/*adverse effects
Emergence Delirium/diagnosis/*epidemiology/etiology
Female
Frailty/diagnosis/*epidemiology
Geriatric Assessment/statistics & numerical data
Health Care Costs/statistics & numerical data
Humans
Length of Stay/economics/statistics & numerical data
Male
Middle Aged
Prospective Studies
Retrospective Studies
Risk Assessment
Risk Factors

Delirium and other neuropsychiatric manifestations of COVID-19 infection in people with preexisting psychiatric disorders: a systematic review van Reekum, E. A. Rosic, T. Sergeant, A. Sanger, N. Rodrigues, M. Rebinsky, R. Panesar, B. Deck, E. Kim, N. Woo, J. D'Elia, A. Hillmer, A. Dufort, A. Sanger, S. Thabane, L. Mbuagbaw, L. Samaan, Z. J Med Case Rep 2021

Bias
*covid-19
*Delirium/epidemiology
Humans
Pandemics
SARS-CoV-2
Covid-19
Case reports
Delirium
Internal medicine
Mental disorders
Pandemic
Psychiatric disorder
Systematic review

Suvorexant with or without ramelteon to prevent delirium: a systematic review and meta-analysis Tian, Y. Qin, Z. Han, Y. Psychogeriatrics 2021

delirium
ramelteon
suvorexant
systematic review and meta-analysis

Nurses' Experience of Caring for Patients with Delirium: Systematic Review and Qualitative Evidence Synthesis Thomas, N. Coleman, M. Terry, D. Nurs Rep 2021

anxiety
assessment
delirium
education
nurse
patient
peers
stress
support

Understanding the decision-making of critical care nurses when restraining a patient with psychomotor agitation secondary to hyperactive delirium: A 'Think Aloud' study Teece, A. Baker, J. Smith, H J Clin Nurs 2022

Critical Care
*Delirium
Humans
*Nursing Staff, Hospital
Psychomotor Agitation
Restraint, Physical

Reduced Electroencephalogram Complexity in Postoperative Delirium Tanabe, S. Parker, M. Lennertz, R. Pearce, R. A. Banks, M. I. Sanders, R. D. J Gerontol A Biol Sci Med Sci 2021

*Age-related pathology
*Inflammation
*Neurodegeneration

Using Telehealth to Improve the Accuracy of Delirium Screening by Bedside Critical Care Nurses Sinvani, L. Hertz, C. Chandra, S. Ilyas, A. Ardito, S. Hajizadeh, N. Am J Crit Care 2022
Melatonin for prevention of postoperative delirium after lower limb fracture surgery in elderly patients (DELIRLESS): study protocol for a multicentre randomised controlled trial Sigaut, S. Couffignal, C. Esposito-Farèse, M. Degos, V. Molliex, S. Boddaert, J. Raynaud-Simon, A. Durand-Zaleski, I. Marcault, E. Jacota, M. Dahmani, S. Paugam-Burtz, C. Weiss, E. BMJ Open 2021

anaesthesia in orthopaedics
delirium & cognitive disorders
geriatric medicine
hip

Management of delirium in a medical and surgical intensive care unit Shivji, S. Stabler, S. N. Boyce, K. Haljan, G. J. McGloin, R. J Clin Pharm Ther 2021

Aged
Antipsychotic Agents/adverse effects/*therapeutic use
Comorbidity
Delirium/*drug therapy/*epidemiology/therapy
Female
Humans
Intensive Care Units/*organization & administration
Male
Middle Aged
Recurrence
*Respiration, Artificial
Retrospective Studies
Tertiary Care Centers
Time Factors
critical care
delirium
dexmedetomidine
haloperidol
mechanical ventilation
quetiapine

5-HT(3) receptor antagonists decrease the prevalence of postoperative delirium in older patients undergoing orthopedic lower limb surgery Shin, H. J. Yoon, J. Na, H. S. Perioper Med (Lond) 2021

5-HT3 receptor antagonist
Older patient
Postoperative delirium

Neutrophil-Lymphocyte Ratio as a Potential Biomarker for Delirium in the Intensive Care Unit Seo, C. L. Park, J. Y. Park, J. Kim, H. E. Cho, J. Seok, J. H. Kim, J. J. Shin, C. S. Oh, J. Front Psychiatry 2021

C-reactive protein
delirium
inflammatory markers
intensive care unit
neutrophil-lymphocyte ratio