Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Plasma interleukin-6 is a potential predictive biomarker for postoperative delirium among acute type a aortic dissection patients treated with open surgical repair
Authors
Lv, X. C. Lin, Y. Wu, Q. S. Wang, L. Hou, Y. T. Dong, Y. Chen, L. W.
Year
2021
Journal
J Cardiothorac Surg
Abstract

OBJECTIVES: The relationship between inflammatory cytokines and postoperative delirium (POD) remains to be further investigated, especially in patients undergoing acute type A aortic dissection (AAD). Interleukin-6 (IL-6) is involved in the inflammatory process and has recently been identified as a biomarker of cerebral dysfunction. We explored the hypothesis that IL-6 was one of the critical causes of POD after surgical repair of AAD. METHODS: Plasma IL-6 was measured using electrochemiluminescence technology in patients preoperatively and 24 h, 48 h, and 72 h after surgical repair of acute type A aortic dissection. After the first three postoperative days, delirium was evaluated twice daily using the Confusion Assessment Method. ROC curves were used to evaluate the ability of IL-6 measurements to distinguish POD. RESULTS: The incidence of POD was 14.03% (31 of 221 patients). The patients in the POD group were significantly older than the patients in the non-POD group (56.48 ± 11.68 years vs 52.22 ± 10.50 years, P = 0.040). Plasma IL-6 concentrations were significantly higher in the POD group than in the non-POD group at three time points: preoperatively, after 24 h, and after 48 h. The AUC values corresponding to IL-6 preoperatively and 24 h after surgery were 0.73 and 0.72, respectively. CONCLUSIONS: Cerebral dysfunction after the surgical repair of AAD shows elevated stress levels and inflammatory responses. Plasma IL-6 is a potential biomarker to predict the onset of POD in acute type A aortic dissection patients following surgical repair.

PMID

PMC8161913

Keywords

Adult
Aged
Aneurysm, Dissecting/ surgery
Aortic Aneurysm/ surgery
Area Under Curve
Biomarkers/blood
Delirium/ blood/etiology
Humans
Interleukin-6/ blood
Male
Middle Aged
Postoperative Complications/blood/etiology
ROC Curve
Retrospective Studies
Aortic dissection
Inflammatory cytokines
Interleukin-6
Postoperative delirium

Page(s)
146
Issue
1

Search:
Total Records Found: 6347, showing 100 per page
TitleAuthorsJournalYearKeywords
Safety and Effectiveness of Perospirone in Comparison to Risperidone for Treatment of Delirium in Patients with Advanced Cancer: A Multicenter Prospective Observational Study in Real-World Psycho-Oncology Settings Inoue, S. Maeda, I. Ogawa, A. Yoshiuchi, K. Terada, S. Yamada, N. Acta Med Okayama 2022

Aged
*Antipsychotic Agents/adverse effects
*Delirium/chemically induced/etiology
Humans
Isoindoles
*Neoplasms/complications/drug therapy
Psycho-Oncology
Risperidone/adverse effects
Thiazoles
cancer
delirium
perospirone
risperidone

Higher Grade Glioma Increases the Risk of Postoperative Delirium: Deficient Brain Compensation Might Be a Potential Mechanism of Postoperative Delirium Huang, H. W. Zhang, X. K. Li, H. Y. Wang, Y. G. Jing, B. Chen, Y. Patel, M. B. Ely, E. W. Liu, Y. O. Zhou, J. X. Lin, S. Zhang, G. B. Front Aging Neurosci 2022

brain cognitive compensation
conceptual model
frontal lobe glioma
postoperative delirium
structural and functional MRI

Fluconazole-induced delirium in an older patient with schizophrenia Hu, T. M. Wu, C. L. Psychogeriatrics 2022
Knowledge assessment is key to identifying the training needs of delirium care Ho, M. H. Intensive Crit Care Nurs 2022

*Delirium/nursing/therapy
Humans
*Intensive Care Units

Anticholinergic Drug Exposure Increases the Risk of Delirium in Older Patients Undergoing Elective Surgery Herrmann, M. L. Boden, C. Maurer, C. Kentischer, F. Mennig, E. Wagner, S. Conzelmann, L. O. Förstner, B. R. Rapp, M. A. von Arnim, C. A. F. Denkinger, M. Eschweiler, G. W. Thomas, C. Front Med (Lausanne) 2022

acute encephalopathy
anticholinergic
delirium
geriatric
postoperative
surgery

A prediction model for delirium after cardiac surgery: Another step towards prevention? Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

*Cardiac Surgical Procedures/adverse effects
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/etiology/prevention & control
Risk Factors

The effect of a dexmedetomidine infusion on delirium in the ICU Herman, J. A. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

*Delirium/chemically induced/drug therapy
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units

Which interventions can reduce post-operative delirium in the elderly? Synthesis of multidisciplinary and pharmacological intervention data Herman, J. Urman, R. D. Urits, I. Kaye, A. D. Viswanath, O. J Clin Anesth 2022

Aged
*Delirium/etiology/prevention & control
Humans
Postoperative Complications/etiology/prevention & control

What is the impact of perioperative cerebral oxygen desaturation on postoperative delirium in old population: a systemic review and meta-analysis He, K. Q. Wang, S. Zhang, W. Liu, Q. Chai, X. Q. Aging Clin Exp Res 2022

Cerebral oxygen saturation
Meta-analysis
Old population
Postoperative delirium
Preoperative monitoring

Midazolam and delirium: can you have it both ways? Greengrass, R. A. Reg Anesth Pain Med 2022

*Delirium/chemically induced/diagnosis
Humans
Hypnotics and Sedatives/adverse effects
*Midazolam/adverse effects
drug-related side effects and adverse reactions
pharmacology
postoperative complications

Music Interventions and Delirium in Adults: A Systematic Literature Review and Meta-Analysis Golubovic, J. Neerland, B. E. Aune, D. Baker, F. A. Brain Sci 2022

acute confusion
delirium
meta-analysis
music interventions
music therapy
prevention
systematic review
treatment

In older adults having hip fracture surgery, regional vs. general anesthesia did not reduce postoperative delirium Gill, S. S. Ann Intern Med 2022

Aged
Anesthesia, General/adverse effects
*Delirium/prevention & control
*Hip Fractures/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/prevention & control

Relationship between preoperative anxiety and onset of delirium after cardiovascular surgery in elderly patients: focus on personality and coping process Fukunaga, H. Sugawara, H. Koyama, A. Okamoto, K. Fukui, T. Ishikawa, T. Takebayashi, M. Sekiyama, K. Hashimoto, M. Psychogeriatrics 2022

agreeableness
anxiety
delirium
personality

Identifying Delirium in Persons With Moderate or Severe Dementia: Review of Challenges and an Illustrative Approach Fong, T. G. Hshieh, T. T. Tabloski, P. A. Metzger, E. D. Arias, F. Heintz, H. L. Patrick, R. E. Lapid, M. I. Schmitt, E. M. Harper, D. G. Forester, B. P. Inouye, S. K. Am J Geriatr Psychiatry 2022

Advanced dementia
Ect
delirium
delirium superimposed on dementia

Depression is associated with delirium after cardiac surgery - A population-based cohort study Falk, A. Kåhlin, J. Nymark, C. Hultgren, R. Stenman, M. Interact Cardiovasc Thorac Surg 2022

Cardiac surgery
Phq-9
depression
postoperative delirium
risk factors
screening

Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. J Clin Nurs 2022

critically ill
delirium
incidence
intensive care unit
risk factors

Incidence, characteristics and risk factors of delirium in the intensive care unit: An observational study Erbay Dalli, Ö Kelebek Girgin, N. Kahveci, F. J Clin Nurs 2022

critically ill
delirium
incidence
intensive care unit
risk factors

Association Between Perioperative Medication Use and Postoperative Delirium and Cognition in Older Adults Undergoing Elective Noncardiac Surgery Duprey, M. S. Devlin, J. W. Griffith, J. L. Travison, T. G. Briesacher, B. A. Jones, R. Saczynski, J. S. Schmitt, E. M. Gou, Y. Marcantonio, E. R. Inouye, S. K. Anesth Analg 2022

Aged
Analgesics, Opioid
*Antipsychotic Agents
Benzodiazepines
Cognition
*Delirium/chemically induced/diagnosis/epidemiology
Humans
Postoperative Complications/diagnosis/epidemiology/etiology
Prospective Studies
Risk Factors

Comparison of incidence of emergence delirium in pediatric patients with three different techniques of general anesthesia using sevoflurane and propofol: a randomized controlled trial Deepak, M. Shilpa, G. Nikhil, K. Ankur, S. Rakesh, K. Swati, C. Akhil, G. Pradeep, B. Braz J Anesthesiol 2022
Delirium and long-term psychopathology following surgery in older adults de Mul, N. van den Bos, Lmec Kant, I. M. J. van Montfort, S. J. T. Schellekens, W. M. Cremer, O. L. Slooter, A. J. C. J Psychosom Res 2022

Aged
Anxiety/epidemiology
*Delirium/diagnosis/epidemiology/etiology
Humans
Male
Postoperative Complications/diagnosis/epidemiology/etiology
Risk Factors
*Stress Disorders, Post-Traumatic/diagnosis/epidemiology/etiology
Anxiety and PTSS
Depression
Elderly
Postoperative delirium
Postoperative psychopathology

Study protocol to test the efficacy of self-administration of dexmedetomidine sedative therapy on anxiety, delirium, and ventilator days in critically ill mechanically ventilated patients: an open-label randomized clinical trial Chlan, L. L. Weinert, C. R. Tracy, M. F. Skaar, D. J. Gajic, O. Ask, J. Mandrekar, J. Trials 2022

Aftercare
Analgesics, Opioid
Anxiety/diagnosis/therapy
*covid-19
Critical Illness
*Delirium/diagnosis/drug therapy/etiology
*Dexmedetomidine/adverse effects
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units
Pandemics
Patient Discharge
Quality of Life
Randomized Controlled Trials as Topic
Respiration, Artificial/adverse effects/methods
Ventilators, Mechanical
Anxiety
Clinical trial
Intensive care
Mechanical ventilation
Sedation

Corticosteroids in patients undergoing cardiac surgery: A meta-analysis of 12,559 patients Chen, L. Xiang, F. Hu, Y. Perfusion 2022

cardiac surgery
corticosteroid
in-hospital mortality
meta-analysis
randomized controlled trial

Postoperative outcomes in older surgical patients with preoperative cognitive impairment: A systematic review and meta-analysis Chen, L. Au, E. Saripella, A. Kapoor, P. Yan, E. Wong, J. Tang-Wai, D. F. Gold, D. Riazi, S. Suen, C. He, D. Englesakis, M. Nagappa, M. Chung, F. J Clin Anesth 2022

Cognitive impairment
Delirium
Dementia
Older adults
Postoperative complications
Surgery

Benzodiazepine-Based Sedation Did Not Add an Independent Risk of Delirium? Cai, X. Gao, R. Zhang, S. Chen, C. Crit Care Med 2022

*Benzodiazepines/adverse effects
*Delirium/drug therapy
Humans
Hypnotics and Sedatives/adverse effects
Intensive Care Units
interest.

Natural language processing and detecting delirium Burki, T. Lancet Respir Med 2022
Delirium risk factors in hospitalized patient: a comprehensive evaluation of underlying diseases and medications in different wards of a large Urban Hospital Center in Iran Arbabi, M. Ziaei, E. Amini, B. Ghadimi, H. Rashidi, F. Shohanizad, N. Moradi, S. Beikmarzehei, A. Hasanzadeh, A. Parsaei, A. BMC Anesthesiol 2022

*Delirium/epidemiology
Hospitals, Urban
Humans
Iran/epidemiology
Prospective Studies
Risk Factors
Confusion
Delirium
Dementia
Hospitalization
Neoplasms
Neurological diseases
research.

Depression and anxiety increase the odds of developing delirium in ICU patients; a prospective observational study Arbabi, M. Dezhdar, Z. Amini, B. Dehnavi, A. Z. Ghasemi, M. Cogn Neuropsychiatry 2022

Anxiety
*Delirium/complications/diagnosis/epidemiology
Depression
Humans
Intensive Care Units
Vision Disorders/complications
*Depression
*hads
*icu
*anxiety
*delirium

Andersen-Ranberg, N. Poulsen, L. M. Perner, A. Hästbacka, J. Morgan, M. P. G. Citerio, G. Oxenbøll-Collet, M. Weber, S. O. Andreasen, A. S. Bestle, M. H. Uslu, B. Pedersen, H. B. S. Nielsen, L. G. Damgaard, K. Jensen, T. B. Sommer, T. Dey, N. Mathiesen, Agents intervening against delirium in the intensive care unit trial-Protocol for a secondary Bayesian analysis Acta Anaesthesiol Scand 2022

Bayesian statistics
Delirium
Icu
haloperidol

Sleep monitoring challenges in patients with neurocognitive disorders: A cross-sectional analysis of missing data from activity trackers Ahuja, M. Siddhpuria, S. Reppas-Rindlisbacher, C. Wong, E. Gormley, J. Lee, J. Patterson, C. Health Sci Rep 2022

activity monitor
delirium
dementia
hospitalized older adults
neurocognitive disorder

The Dilemma of Treating Delirium: the Conundrum of Drug Management Agar, M. R. Amgarth-Duff, I. Curr Treat Options Oncol 2022

Antipsychotics
Benzodiazepines
Delirium
Palliative care
Treatment

Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan Abe, H. Sumitani, M. Matsui, H. Inoue, R. Konishi, M. Fushimi, K. Uchida, K. Yasunaga, H. Anesth Analg 2022

Gabapentinoid Use Is Associated With Reduced Occurrence of Hyperactive Delirium in Older Cancer Patients Undergoing Chemotherapy: A Nationwide Retrospective Cohort Study in Japan

Incidence, predictors and health outcomes of delirium in very old hospitalized patients: a prospective cohort study Zhang, M. Zhang, X. Gao, L. Yue, J. Jiang, X. BMC Geriatr 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/epidemiology/etiology
Hospitalization
Humans
Incidence
Outcome Assessment, Health Care
Prospective Studies
Cognitive impairment
Delirium
Prediction model
Risk factor
Very old patients

The effect of delirium information training given to intensive care nurses on patient care: quasi-experimental study Yıldırım, F. Türkleş, S. Altundal Duru, H. PeerJ 2022

Checklist
Delirium
Intensive care unit
Nursing
Patient care
Training

Mechanical Bowel Preparation Is a Risk Factor for Postoperative Delirium as It Alters the Gut Microbiota Composition: A Prospective Randomized Single-Center Study Yang, Z. Tong, C. Qian, X. Wang, H. Wang, Y. Front Aging Neurosci 2022

gastrectomy
gut microbiota
mechanical bowel preparation (MBP)
perioperative interventions
postoperative delirium (POD)
commercial or financial relationships that could be construed as a potential
conflict of interest.

The Mini-Cog: A simple screening tool for cognitive impairment useful in predicting the risk of delirium after major urological cancer surgery Yajima, S. Nakanishi, Y. Matsumoto, S. Ookubo, N. Tanabe, K. Kataoka, M. Masuda, H. Geriatr Gerontol Int 2022

Activities of Daily Living
*Cognitive Dysfunction/psychology
*Delirium/diagnosis/etiology/psychology
Early Detection of Cancer
Humans
Mental Status and Dementia Tests
Risk Factors
*Urologic Neoplasms/complications/diagnosis/surgery
cognitive dysfunction
delirium
dementia
robotic surgery
urology

A Novel Radiomics-Based Machine Learning Framework for Prediction of Acute Kidney Injury-Related Delirium in Patients Who Underwent Cardiovascular Surgery Xue, X. Chen, W. Chen, X. Comput Math Methods Med 2022

*Acute Kidney Injury/diagnostic imaging/etiology
*Delirium/diagnostic imaging/etiology
Humans
Machine Learning
Retrospective Studies
Support Vector Machine

The Effect of Preoperative Methylprednisolone on Postoperative Delirium in Older Patients Undergoing Gastrointestinal Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial Xiang, X. B. Chen, H. Wu, Y. L. Wang, K. Yue, X. Cheng, X. Q. J Gerontol A Biol Sci Med Sci 2022

Aged
Brain-Derived Neurotrophic Factor
*Delirium/epidemiology/etiology/prevention & control
*Digestive System Surgical Procedures/adverse effects
Double-Blind Method
Heparitin Sulfate
Humans
Methylprednisolone/therapeutic use
Postoperative Complications/epidemiology/prevention & control
Syndecan-1
Tumor Necrosis Factor-alpha
*Brain-derived neurotrophic factor
*Delirium
*Heparan sulfate
*Methylprednisolone
*Syndecan-1
*Tumor necrosis factor-α

Head-to-head comparison of 14 prediction models for postoperative delirium in elderly non-ICU patients: an external validation study Wong, C. K. van Munster, B. C. Hatseras, A. Huis In 't Veld, E. van Leeuwen, B. L. de Rooij, S. E. Pleijhuis, R. G. BMJ Open 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
Humans
Prospective Studies
delirium & cognitive disorders
geriatric medicine
internal medicine
risk management
surgery

Impact of a dementia-friendly program on detection and management of patients with cognitive impairment and delirium in acute-care hospital units: a controlled clinical trial design Weldingh, N. M. Mellingsæter, M. R. Hegna, B. W. Benth, J. S. Einvik, G. Juliebø, V. Thommessen, B. Kirkevold, M. BMC Geriatr 2022

Aged
Aged, 80 and over
Clinical Trials as Topic
*Cognitive Dysfunction/diagnosis/therapy
*Delirium/diagnosis/psychology/therapy
*Dementia/diagnosis/psychology/therapy
Hospital Units
Humans
Cognitive impairment
Delirium
Delirium detection
Delirium prevention
Delirium screening
Delirium treatment measures
Dementia-friendly hospital
Implementation

Influence of Patient-Specific Covariates on Test Validity of Two Delirium Screening Instruments in Neurocritical Care Patients (DEMON-ICU) Weiss, B. Paul, N. Spies, C. D. Ullrich, D. Ansorge, I. Salih, F. Wolf, S. Luetz, A. Neurocrit Care 2022

Critical Care/methods
*Delirium/diagnosis
Humans
Intensive Care Units
*Ischemic Attack, Transient
Reproducibility of Results
*Stroke/complications/diagnosis
*cam-icu
*Critical care
*Delirium
*Hypnotics and sedatives
*icdsc
*Neurocritical care
*Sensitivity
*Specificity

Development and Validation of a Postoperative Delirium Prediction Model for Elderly Orthopedic Patients in the Intensive Care Unit Wang, G. Zhang, L. Qi, Y. Chen, G. Zhou, J. Zhu, H. Hao, Y. J Healthc Eng 2022

Aged
Critical Care
*Delirium/diagnosis/etiology/prevention & control
Humans
Intensive Care Units
Prospective Studies
ROC Curve

Effects of Atorvastatin Therapy on Postoperative Delirium After Malignant Tumor Surgeries in Older Adults Wan, R. Cai, S. Pan, D. Yang, W. Zhou, R. Neuropsychiatr Dis Treat 2022

30-day all-cause mortality
Rct
atorvastatin
outcome
postoperative delirium

Psychometric Properties of a Delirium Severity Score for Older Adults and Association With Hospital and Posthospital Outcomes Vasunilashorn, S. M. Fong, T. G. Helfand, B. K. I. Hshieh, T. T. Marcantonio, E. R. Metzger, E. D. Schmitt, E. M. Tabloski, P. A. Travison, T. G. Gou, Y. Jones, R. N. Inouye, S. K. JAMA Netw Open 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/therapy
Female
Hospitals
Humans
Prospective Studies
Psychometrics
Reproducibility of Results

Delirium can be safely managed in the community through implementation of a community toolkit: a proof-of-concept pilot study Vardy, E. Roberts, S. Pratt, H. Future Healthc J 2022

assessment
community
delirium
management
pilot

Delirium as a Presenting Symptom of COVID-19 Tyson, B. Shahein, A. Erdodi, L. Tyson, L. Tyson, R. Ghomi, R. Agarwal, P. Cogn Behav Neurol 2022
The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study Tsui, A. Searle, S. D. Bowden, H. Hoffmann, K. Hornby, J. Goslett, A. Weston-Clarke, M. Howes, L. H. Street, R. Perera, R. Taee, K. Kustermann, C. Chitalu, P. Razavi, B. Magni, F. Das, D. Kim, S. Chaturvedi, N. Sampson, E. L. Rockwood, K. Cunningham, C. E Lancet Healthy Longev 2022
Delirium with visual hallucinations induced by low-dose olanzapine Takeuchi, N. Makino, T. Nishihara, M. Psychogeriatrics 2022

*Antipsychotic Agents/adverse effects
Benzodiazepines/adverse effects
*Delirium/chemically induced/drug therapy
Hallucinations/chemically induced/drug therapy
Humans
Olanzapine/adverse effects

Catatonia and Delirium: Similarity and Overlap of Acute Brain Dysfunction Tachibana, M. Ishizuka, K. Inada, T. Front Psychiatry 2022

acute brain dysfunction
catatonia
delirium
diagnostic concepts
overlap
commercial or financial relationships that could be construed as a potential
conflict of interest.

Association between stress hyperglycemia ratio and delirium in older hospitalized patients: a cohort study Song, Q. Dai, M. Zhao, Y. Lin, T. Huang, L. Yue, J. BMC Geriatr 2022

Aged
Aged, 80 and over
Cohort Studies
*Delirium/diagnosis/epidemiology
Female
Glycated Hemoglobin A
Hospitalization
Humans
*Hyperglycemia/diagnosis/epidemiology
Male
Delirium
Glycosylated hemoglobin
Hyperglycemia
Older people
Stress hyperglycemia ratio

Machine Learning to Identify Psychomotor Behaviors of Delirium for Patients in Long-Term Care Facility Son, C. S. Kang, W. S. Lee, J. H. Moon, K. J. IEEE J Biomed Health Inform 2022

Adult
Dehydration
*Delirium/diagnosis
*Dementia
Humans
Long-Term Care
Machine Learning
Pilot Projects
Prospective Studies
*Sleep Wake Disorders

Parents' Time Perspective as a Predictor of Child's Postsurgical Pain, Emergence Delirium, and Parents' Posttraumatic Stress Disorder Symptoms after Child's Surgery Sobol, M. Sobol, M. K. Children (Basel) 2022

Ptsd
child pain
emergence delirium
surgery
time perspective

Applicability of the interventions recommended for patients at risk or with delirium in medical and post-acute settings: a systematic review and a Nominal Group Technique study Sist, L. Ugenti, N. V. Donati, G. Cedioli, S. Mansutti, I. Zanetti, E. Macchiarulo, M. Messina, R. Rucci, P. Palese, A. Aging Clin Exp Res 2022

Applicability
Delirium
Interventions
Medical units
Nursing
Post-acute units
Risk
Treatments

Prevalence and features of delirium in older patients admitted to rehabilitation facilities: a multicenter study Sidoli, C. Zambon, A. Tassistro, E. Rossi, E. Mossello, E. Inzitari, M. Cherubini, A. Marengoni, A. Morandi, A. Bellelli, G. Aging Clin Exp Res 2022

Delirium
Dementia
Disability
Physical restraint
Rehabilitation

Nomogram Models for Predicting Delirium of Patients in Emergency Intensive Care Unit: A Retrospective Cohort Study Shi, Y. Wang, H. Zhang, L. Zhang, M. Shi, X. Pei, H. Bai, Z. Int J Gen Med 2022

area under curve
delirium
emergency intensive care unit
model
prediction

Effect of midazolam on delirium in critically ill patients: a propensity score analysis Shi, H. J. Yuan, R. X. Zhang, J. Z. Chen, J. H. Hu, A. M. J Int Med Res 2022

Midazolam

delirium

critical care

propensity score analysis

cohort study

risk factor

Prediction of Postoperative Delirium After Cardiac Surgery with A Quick Test of Cognitive Speed, Mini-Mental State Examination and Hospital Anxiety and Depression Scale Segernäs, A. Skoog, J. Ahlgren Andersson, E. Almerud Österberg, S. Thulesius, H. Zachrisson, H. Clin Interv Aging 2022

Aged
Anxiety/diagnosis
*Cardiac Surgical Procedures/adverse effects
Cognition
*Delirium/diagnosis/etiology
Depression/complications
Hospitals
Humans
Postoperative Complications/diagnosis/etiology
A Quick Test of Cognitive Speed
Mini Mental State Examination
The Hospital Anxiety and Depression Scale
cardiopulmonary bypass
postoperative delirium

A retrospective comparison of haloperidol and hydroxyzine combination therapy with haloperidol alone in the treatment of overactive delirium Sato, J. Tanaka, R. Support Care Cancer 2022

*Antipsychotic Agents/therapeutic use
*Delirium/diagnosis/drug therapy/etiology
Haloperidol/therapeutic use
Humans
Hydroxyzine/therapeutic use
Hypnotics and Sedatives/therapeutic use
Intensive Care Units
Retrospective Studies
Delirium
Haloperidol
Hydroxyzine
Intensive Care Delirium Screening Checklist (ICDSC)

Serum folate deficiency and the risks of dementia and all-cause mortality: a national study of old age Rotstein, A. Kodesh, A. Goldberg, Y. Reichenberg, A. Levine, S. Z. Evid Based Ment Health 2022

Aged
*Dementia/etiology
Folic Acid/therapeutic use
*Folic Acid Deficiency/complications/drug therapy
Humans
Proportional Hazards Models
Prospective Studies
adult psychiatry
delirium & cognitive disorders

Incidence of Postoperative Delirium Is Similar with Regional and General Anesthesia Rosenberg, K. Am J Nurs 2022

Aged
Anesthesia, General/adverse effects
*Delirium/epidemiology/etiology
*Hip Fractures/complications/epidemiology/surgery
Humans
Incidence
Postoperative Complications/epidemiology/etiology

Delirium and Delirium Severity Predict the Trajectory of the Hierarchical Assessment of Balance and Mobility in Hospitalized Older People: Findings From the DECIDE Study Richardson, S. Murray, J. Davis, D. Stephan, B. C. M. Robinson, L. Brayne, C. Barnes, L. Parker, S. Sayer, A. A. Dodds, R. M. Allan, L. J Gerontol A Biol Sci Med Sci 2022

Aged
*Delirium/diagnosis
*Hospitalization
Humans
*Epidemiology
*Hospital related
*Physical function

Anesthetic Practice Trends and Perceptions Toward Postoperative Delirium: A Mixed-Methods Analysis Ragheb, J. Norcott, A. E. Iskander, M. Brooks, J. McKinney, A. Mentz, G. Vlisides, P. E Anesth Analg 2022
Preoperative Vitamin D Deficiency Is Associated With Postoperative Delirium in Critically Ill Patients Qiu, Y. Sessler, D. I. Chen, L. Halvorson, S. Cohen, B. Bravo, M. Ince, I. Maheshwari, K. Kurz, A. J Intensive Care Med 2022

Adult
Critical Illness
*Delirium/epidemiology/etiology
Humans
Intensive Care Units
Retrospective Studies
Vitamin D
*Vitamin D Deficiency/complications/epidemiology
critically ill
deficiency
delirium

Physicians' beliefs and attitudes toward hypoactive delirium in the last days of life Oya, K. Morita, T. Tagami, K. Matsuda, Y. Naito, A. S. Kashiwagi, H. Otani, H. J Pain Symptom Manage 2022

antipsychotic
end-of-life
hypoactive delirium
pharmacological management
terminal delirium

Evidence-Based Guideline on Management of Postoperative Delirium in Older People for Low Resource Setting: Systematic Review Article Mossie, A. Regasa, T. Neme, D. Awoke, Z. Zemedkun, A. Hailu, S. Int J Gen Med 2022

delirium prevention
delirium screening
delirium treatment
elderly people
postoperative delirium

Delirium diagnosis without a gold standard: Evaluating diagnostic accuracy of combined delirium assessment tools Moss, S. J. Hee Lee, C. Doig, C. J. Whalen-Browne, L. Stelfox, H. T. Fiest, K. M. PLoS One 2022

Adult
Bayes Theorem
Critical Care/methods
Cross-Sectional Studies
*Delirium/diagnosis
Humans
Intensive Care Units
Reproducibility of Results
Sensitivity and Specificity

Steroid dosing and delirium after lung transplant surgery Mody, G. N. Choi, B. Townsend, K. Kerwin, C. Larios, D. Boukedes, S. Coppolino, A. Singh, S. Jin, G. Wolfe, D. Mallidi, H. Goldberg, H. Gen Hosp Psychiatry 2022

*Delirium/etiology
Humans
Intensive Care Units
*Lung Transplantation/adverse effects
Psychomotor Agitation
Steroids
Confusion assessment method
Corticosteroids
Delirium
Lung transplantation
Richmond agitation-sedation scale

A systematic review of strategies for preventing delirium in patients undergoing vascular surgery Meulenbroek, A. L. van Mil, S. R. Faes, M. C. Mattace-Raso, F. U. S. Fourneau, I. van der Laan, L. Ann Vasc Surg 2022

Aneurysm of the abdominal aorta
Delirium
Delirium/prevention and control
Peripheral arterial disease
Prehabilitation
Vascular Surgical Procedures

The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement Messé, S. R. Overbey, J. R. Thourani, V. H. Moskowitz, A. J. Gelijns, A. C. Groh, M. A. Mack, M. J. Ailawadi, G. Furie, K. L. Southerland, A. M. James, M. L. Moy, C. S. Gupta, L. Voisine, P. Perrault, L. P. Bowdish, M. E. Gillinov, A. M. O'Gara, P. T. Ou J Thorac Cardiovasc Surg 2022

aortic valve
delirium
neurological outcomes
perioperative management
surgical aortic valve replacement (SAVR)

Tau as a serum biomarker of delirium after major cardiac surgery: a single centre case-control study McKay, T. B. Qu, J. Liang, F. Mueller, A. Wiener-Kronish, J. Xie, Z. Akeju, O. Br J Anaesth 2022

Alzheimer’s disease
cardiopulmonary bypass
cognitive dysfunction
delirium
dementia
phospho-tau
post-surgical complications
tau

Insulinoma: an uncommon cause of delirium McComb, K. Roulston, G. Armstrong, L. Age Ageing 2022

Aged
Aged, 80 and over
*Delirium/complications/etiology
Female
*Frailty/complications
Humans
*Hypoglycemia/diagnosis/etiology
*Insulinoma/complications/diagnosis
*Pancreatic Neoplasms/diagnosis/diagnostic imaging
*delirium
*frailty
*hypoglycaemia
*insulinoma
*older people

The Twilight Zone: Oxybutynin Overuse Exacerbating Delirium Marthi, S. Pomerantz, M. A. Mernan, A. J. Berlow, Y. A. J Geriatr Psychiatry Neurol 2022

anticholinergic medications
behavioral disturbance
central nervous system
cognitive impairment
delirium
geriatric psychiatry

Corrigendum: Risk Factors for Delirium Are Different in the Very Old: A Comparative One-Year Prospective Cohort Study of 5,831 Patients Marquetand, J. Bode, L. Fuchs, S. Hildenbrand, F. Ernst, J. von Känel, R. Boettger, S. Front Psychiatry 2022

comparison
delirium
prospective
risk factors
very old

The development of the MENTOR_D nursing intervention: Supporting family involvement in delirium management Mailhot, T. Cossette, S. Lavoie, P. Maheu-Cadotte, M. A. Fontaine, G. Bourbonnais, A. Côté, J. Int J Older People Nurs 2022

delirium
family caregivers
intervention development
nursing intervention

Factors Associated With Severity of Delirium Complicating COVID-19 in Intensive Care Units Madonna, D. Enrico, P. Ciappolino, V. Boscutti, A. Colombo, E. Turtulici, N. Cantù, F. Cereda, G. Delvecchio, G. De Falco, S. Chierichetti, M. Savioli, M. Grasselli, G. Brambilla, P. Front Neurol 2022

Ards
Covid-19
ICUs
cognition
delirium
prognosis
psychiatric symptoms

An open-label clinical trial of oral transmucosal haloperidol and oral transmucosal olanzapine in the treatment of terminal delirium at home Lyu, X. J. Kan, A. D. Chong, P. H. Lin, K. Koh, Y. H. Yeo, Z. Z. Trials 2022

*Antipsychotic Agents/adverse effects
*Delirium/diagnosis/drug therapy
Haloperidol/adverse effects
Humans
Olanzapine/adverse effects
Psychomotor Agitation/drug therapy
End of life
Haloperidol
Home hospice
Olanzapine
Palliative care
Terminal delirium

Family-centred care interventions to reduce the delirium prevalence in critically ill patients: A systematic review and meta-analysis Lin, L. Peng, Y. Zhang, H. Huang, X. Chen, L. Lin, Y. Nurs Open 2022

delirium
family-centred care
intensive care unit
meta-analysis

White-Cell Derived Inflammatory Biomarkers in Prediction of Postoperative Delirium in Elderly Patients Undergoing Surgery for Lower Limb Fracture Under Non-General Anaesthesia Li, X. Wang, G. He, Y. Wang, Z. Zhang, M. Clin Interv Aging 2022

Aged
Benzodiazepines
Biomarkers
Blood Platelets
C-Reactive Protein
*Delirium/diagnosis/epidemiology/etiology
Humans
Lower Extremity
Platelet Count
Retrospective Studies
anaesthesia method
inflammation
lower limb fracture
neutrophil-to-lymphocyte ratio
postoperative delirium

Comparative salary-related costs of a brief app-directed delirium identification protocol by hospitalists, nurses, and nursing assistants Leslie, D. L. Fick, D. M. Moore, A. Inouye, S. K. Jung, Y. Ngo, L. H. Boltz, M. Husser, E. Shrestha, P. Boustani, M. Marcantonio, E. R. J Am Geriatr Soc 2022

cost-analysis
delirium
implementation
screening

Investigation and treatment of asymptomatic bacteriuria in older patients with delirium: a cross-sectional survey of Canadian physicians Laguë, A. Boucher, V. Joo, P. Yadav, K. Morasse, C. Émond, M. Cjem 2022

Aged
Anti-Bacterial Agents/therapeutic use
*Bacteriuria/diagnosis/drug therapy
Canada/epidemiology
Cross-Sectional Studies
*Delirium/diagnosis/drug therapy/epidemiology
Female
Humans
Male
*Physicians
*Asymptomatic bacteriuria
*Delirium
*Geriatric

APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort Kuo, C. L. Pilling, L. C. Atkins, J. L. Fortinsky, R. H. Kuchel, G. A. Melzer, D. J Gerontol A Biol Sci Med Sci 2022

Alleles
*Apolipoprotein E4/genetics
Apolipoproteins E/genetics
*covid-19
*Delirium/etiology/genetics
Genotype
Hospitalization
Humans
United Kingdom/epidemiology

Nurses' Knowledge about Delirium in the Group of Intensive Care Units Patients Krupa, S. Friganović, A. Oomen, B. Benko, S. Mędrzycka-Dąbrowska, W. Int J Environ Res Public Health 2022

Clinical Competence
Critical Care
*Delirium/diagnosis
Humans
Intensive Care Units
*Nursing Staff, Hospital
*collective subject discourse
*critical care
*delirium

Early Ambulation to Prevent Delirium After Long-Time Head and Neck Cancer Surgery Kim, J. H. Lee, Y. S. Kim, Y. H. Cho, K. J. Jung, Y. H. Choi, S. H. Nam, S. Y. Kim, S. Y. Front Surg 2022

ambulation
delirium
head and neck cancer
postoperative care
survival

The effect of regional nerve block on perioperative delirium in hip fracture surgery for the elderly: A systematic review and meta-analysis of randomized controlled trials Kim, C. H. Yang, J. Y. Min, C. H. Shon, H. C. Kim, J. W. Lim, E. J. Orthop Traumatol Surg Res 2022

Aged
*Delirium/epidemiology/etiology/prevention & control
*Hip Fractures/complications/surgery
Humans
*Nerve Block/adverse effects
Pain Management/methods
Randomized Controlled Trials as Topic
*Cognitive impairment
*Delirium
*Hip fracture
*Meta-analysis
*Regional nerve block

Role of multicomponent non-pharmacological nursing interventions on delirium prevention: A randomized controlled study Kasapoğlu, E. S. Enç, N. Geriatr Nurs 2022

Critical Illness
*Delirium/prevention & control
Humans
Intensive Care Units
Research Design
Delirium
Eye patch
Family voice
Multicomponent non-pharmacological nursing interventions

Early Intervention of Perioperative Delirium in Older Patients (>60 years) with Hip Fracture: A Randomized Controlled Study Jing, G. W. Xie, Q. Tong, J. Liu, L. Z. Jiang, X. Si, L. Orthop Surg 2022

Delirium
Early intervention
Elderly
Hip fracture
Perioperative

Functional Outcome in Patients with Chronic Subdural Hematoma: Postoperative Delirium and Operative Procedure Ishida, T. Inoue, T. Inoue, T. Saito, A. Suzuki, S. Uenohara, H. Tominaga, T. Neurol Med Chir (Tokyo) 2022

*Delirium/etiology
Drainage/methods
*Hematoma, Subdural, Chronic/epidemiology/surgery
Humans
Recurrence
Retrospective Studies
Treatment Outcome
chronic subdural hematoma
functional outcome
operative procedure
postoperative delirium

Delirium in geriatric patients Iglseder, B. Frühwald, T. Jagsch, C. Wien Med Wochenschr 2022

Aged
*Delirium/diagnosis/etiology/prevention & control
*Drug-Related Side Effects and Adverse Reactions
Humans
Prognosis
Risk Factors
Acute confusional state
Cognitive disorders
Encephalopathy
Older people
Prevention
interests.

Recognizing Intensive Care Unit Delirium: Are Critical Care Nurses Ready? Ho, M. H. Chang, H. R. Liu, M. F. Chen, K. H. Shen Hsiao, S. T. Traynor, V. J Nurs Res 2022
Effect of an evidence-based poster on the knowledge of delirium and its prevention in student nurses: A quasi-experimental study Glass, G. F. Tan, H. Chan, E. Y. Contemp Nurse 2022

Aged
Aged, 80 and over
*Delirium/diagnosis/prevention & control
Humans
Prospective Studies
*Students, Nursing
delirium
evidence-based practice
nursing
students

Lack of Association Between Perioperative Medication and Postoperative Delirium in Hip Fracture Patients in an Orthogeriatric Care Pathway Genet, B. Lamy, T. Cohen-Bittan, J. Glasman, P. Verny, M. Riou, B. Boddaert, J. Zerah, L. J Am Med Dir Assoc 2022

Aged
Aged, 80 and over
Critical Pathways
*Delirium/epidemiology/etiology
*Hip Fractures/epidemiology/surgery
Humans
Postoperative Complications/epidemiology
Retrospective Studies
Risk Factors
Postoperative delirium
hip surgery
older person
orthogeriatric care
perioperative drugs

Dexmedetomidine after Cardiac Surgery for Prevention of Delirium (EXACTUM) trial protocol: a multicentre randomised, double-blind, placebo-controlled trial Gargadennec, T. Oilleau, J. F. Rozec, B. Nesseler, N. Lasocki, S. Futier, E. Amour, J. Durand, M. Bougle, A. Kerforne, T. Consigny, M. Eddi, D. Huet, O. BMJ Open 2022

Aged
*Cardiac Surgical Procedures/adverse effects
*Delirium/epidemiology/etiology/prevention & control
*Dexmedetomidine/therapeutic use
Double-Blind Method
Humans
Multicenter Studies as Topic
Quality of Life
Randomized Controlled Trials as Topic
Cardiac surgery
Delirium
Dexmedetomidine
Intensive care

Validation of E-PRE-DELIRIC in cardiac surgical ICU delirium: A retrospective cohort study Gao, W. Zhang, Y. Jin, J. Nurs Crit Care 2022

Adult
*Cardiac Surgical Procedures/adverse effects
*Delirium/epidemiology
Hospitalization
Humans
Intensive Care Units
Retrospective Studies
E-pre-deliric
cardiac surgery ICU
clinical prediction
delirium
early prediction model

Association Between Sedative Medication Administration and Delirium Development in a Medical Intensive Care Unit Franz, N. D. Alaniz, C. Miller, J. T. Farina, N. J Pharm Pract 2022

benzodiazepine
delirium
dexmedetomidine
sedation

Nurse-Driven Assessment, Prevention, and Management of Delirium on an Acute Inpatient Neurology Unit Francisco, M. A. Gesell, T. Meletis, S. Bohr, N. L. Gleason, L. J. J Nurs Care Qual 2022
Delirium the next frontier Fong, T. G. Inouye, S. K. J Gerontol A Biol Sci Med Sci 2022

*Delirium/diagnosis/etiology
Humans
Intensive Care Units

Presurgical Thalamus Volume in Postoperative Delirium: A Longitudinal Observational Cohort Study in Older Patients Fislage, M. Feinkohl, I. Pischon, T. Spies, C. D. Borchers, F. Winterer, G. Zacharias, N. Anesth Analg 2022
The association between preoperative Mini-Cog© score and postoperative delirium (POD): a retrospective cohort study Fiamanya, S. Ma, S. Yates, D. R. A. Perioper Med (Lond) 2022

Cognitive impairment
Delirium
Mini-Cog©
Preoperative assessment
Screening

Delirium severity in critical patients with COVID-19 from an Infectious Disease Intensive Care Unit Dias, R. Caldas, J. P. Silva-Pinto, A. Costa, A. Sarmento, A. Santos, L. Int J Infect Dis 2022

*COVID-19/complications
*Communicable Diseases
*Delirium/epidemiology/etiology
Female
Humans
Intensive Care Units
Male
Middle Aged
Retrospective Studies
Covid-19
Delirium
Neurologic
SARS-CoV-2
Severe

Health-Related Quality of Life Following Delirium in the PICU Dervan, L. A. Killien, E. Y. Smith, M. B. Watson, R. S. Pediatr Crit Care Med 2022

Aftercare
Child
*Delirium/diagnosis/epidemiology/etiology
Humans
Intensive Care Units, Pediatric
Patient Discharge
Prospective Studies
*Quality of Life
Retrospective Studies

Cuartas, C. F. Davis, M. Valproic Acid in the Management of Delirium Am J Hosp Palliat Care 2022

Adult
*Antipsychotic Agents/therapeutic use
Benzodiazepines/therapeutic use
*Delirium/chemically induced/drug therapy
Humans
Male
Middle Aged
Psychomotor Agitation/drug therapy
Valproic Acid/therapeutic use
Young Adult
acute encephalopathy
agitation
delirium
hyperactive delirium
valproate
valproic acid