Core Outcome Sets for Trials to Prevent and/or Treat Delirium: The Del-COrS Collaboration

Contributed by Louise Rose, BN, MN, PhD, Professor in Critical Care Nursing, Florence Nightingale Faculty of Nursing, Midwifery and Palliative Care, King’s College London, London, UK Delirium is a common, costly and potentially preventable syndrome associated with short- and long-term adverse outcomes for patients, family members, and healthcare organizations. Reassuringly, the numbers of clinical trials […]

World Delirium Awareness Day 2020

 Contributed by Maggie Webb, Research Associate at the Aging Brain Center, Marcus Institute for Aging Research, Hebrew SeniorLife Delirium is a serious, widespread, and morbid syndrome that is prevalent in many healthcare settings, including inpatient care for hospitalized older adults, post-anesthesia care units and post-surgical care, intensive care units, and the emergency department. Delirium can […]

Possible role for the CNS arousal network in delirium

Contributed by Olga Boukrina, Ph.D., Kessler Foundation Delirium is a multicomponent syndrome produced by a set of unique vulnerabilities (e.g., infection, advanced age, decreased cognitive functioning) and compounding causes (e.g., circadian dysregulation, oxidative stress, neuronal aging). The contribution of each individual factor and their interactions present a complicated picture, but unifying themes in this line […]

Improving Delirium Recognition in Long-Term Care Facilities: How to Quickly Detect Altered Mental Status

Contributed by Flavia Barreto Garcez, MD & Thiago J. Avelino-Silva, MD, PhD, Division of Geriatrics, University of São Paulo Medical School Changes in mental status are common in older adults admitted to both acute and long-term care facilities. Although several neuropsychiatric conditions can be responsible for these alterations, delirium is often a key cause.1,2 In […]