Delirium Bibliography

Delirium Bibliography books graphicWhat is the Delirium Bibliography? The searchable Delirium Bibliography page is one of our most popular features, allowing you to quickly gain access to the literature on delirium and acute care of older persons. It is primarily intended for clinicians and researchers interested in exploring these topics. The NIDUS team keeps it updated for you on a monthly basis!

How to Search for Articles: Search by author, title, year, and/or keywords. Each article is indexed by keywords taken from MEDLINE and other relevant databases. Click on the title of the article to read the abstract, journal, etc.

Reference Information

Title
Intensive care unit interventions to promote sleep and circadian biology in reducing incident delirium: a scoping review
Authors
Wilcox, M. E. Burry, L. Englesakis, M. Coman, B. Daou, M. van Haren, F. M. Ely, E. W. Bosma, K. J. Knauert, M. P.
Year
2024
Journal
Thorax
Abstract

RATIONALE/OBJECTIVES: Despite plausible pathophysiological mechanisms, research is needed to confirm the relationship between sleep, circadian rhythm and delirium in patients admitted to the intensive care unit (ICU). The objective of this review is to summarise existing studies promoting, in whole or in part, the normalisation of sleep and circadian biology and their impact on the incidence, prevalence, duration and/or severity of delirium in ICU. METHODS: A sensitive search of electronic databases and conference proceedings was completed in March 2023. Inclusion criteria were English-language studies of any design that evaluated in-ICU non-pharmacological, pharmacological or mixed intervention strategies for promoting sleep or circadian biology and their association with delirium, as assessed at least daily. Data were extracted and independently verified. RESULTS: Of 7886 citations, we included 50 articles. Commonly evaluated interventions include care bundles (n=20), regulation or administration of light therapy (n=5), eye masks and/or earplugs (n=5), one nursing care-focused intervention and pharmacological intervention (eg, melatonin and ramelteon; n=19). The association between these interventions and incident delirium or severity of delirium was mixed. As multiple interventions were incorporated in included studies of care bundles and given that there was variable reporting of compliance with individual elements, identifying which components might have an impact on delirium is challenging. CONCLUSIONS: This scoping review summarises the existing literature as it relates to ICU sleep and circadian disruption (SCD) and delirium in ICU. Further studies are needed to better understand the role of ICU SCD promotion interventions in delirium mitigation.

PMID

PMID: 38350730

 

Keywords

Humans
*Delirium/prevention & control
*Circadian Rhythm/physiology
*Intensive Care Units
Sleep/physiology
Incidence
Melatonin
Critical Care

Page(s)
Issue

Search:
Total Records Found: 6289, showing 100 per page
TitleAuthorsJournalYearKeywords
Evaluating delirium outcomes among older adults in the surgical intensive care unit Pavone, K. J. Jablonski, J. Junker, P. Cacchione, P. Z. Compton, P. Polomano, R. C. Heart Lung 2020

Critical care
Delirium
Elderly
Intensive care
Length of stay
Mortality
Older adult
Readmissions
Sicu

Association between continuous deep sedation and survival time in terminally ill cancer patients Park, S. J. Ahn, H. K. Ahn, H. Y. Han, K. T. Hwang, I. C. Support Care Cancer 2020

Continuous deep sedation
Hospice
Palliative care
Palliative sedation
Sedative
Survival

Liver Transplant Patients with High Preoperative Serum Bilirubin Levels Are at Increased Risk of Postoperative Delirium: A Retrospective Study Park, K. H. Son, H. J. Choi, Y. J. Park, G. H. Lee, Y. S. Park, J. Y. Ri, H. S. Shim, J. R. J Clin Med 2020

bilirubin
complication
liver transplantation
postoperative delirium

Smoking-cessation pharmacotherapy for patients with stroke and TIA: Systematic review Parikh, N. S. Salehi Omran, S. Kamel, H. Elkind, M. S. V. Willey, J. Z. J Clin Neurosci 2020

Cerebrovascular Disease
Pharmacology
Secondary Prevention
Smoking Cessation
Stroke
Transient Ischemic Attack (TIA)

A prospective cohort study on predictors of mortality of delirium in an emergency observational unit Pal, S. Sharma, N. Singh, S. M. Bhutungru, S. Pannu, A. K. QJM 2020

Acute confusional state
Cam-icu
Drs-r-98
Delirium
Emergency department
Intensive care unit
Mortality
Prevalence
Screening

Preoperative Anxiety and Depression Increases the Incidence of Delirium After Coronary Artery Bypass Graft Surgery Pakrad, F. Pakrad, E. Darvishi, N. Poorolajal, J. J Perianesth Nurs 2020

anxiety
coronary artery bypass
delirium
depression
postoperative

Association between fluid overload and delirium/coma in mechanically ventilated patients Ouchi, A. Sakuramoto, H. Hoshino, H. Matsuishi, Y. Sakaguchi, T. Enomoto, Y. Hoshino, T. Shimojo, N. Inoue, Y. Acute Med Surg 2020

Brain dysfunction
delirium
fluid
fluid overload
intensive care

Hallucinations after Cardiac Surgery: A Prospective Observational Study Ottens, T. H. Sommer, I. E. C. Begemann, M. J. Schutte, M. Cramer, M. J. Suyker, W. J. Van Dijk, D. Slooter, A. J. C. Medicina (Kaunas) 2020

cardiothoracic surgery
delirium
hallucinations
neuropsychiatric outcomes

Preoperative sepsis is a predictive factor for 30-day mortality after major lower limb amputation among patients with arteriosclerosis obliterans and diabetes Otsuka, T. Arai, M. Sugimura, K. Sakai, M. Nishizawa, Y. Suzuki, Y. Okamoto, H. Kuroiwa, M. J Orthop Sci 2020
Patient-related and anesthesia-dependent determinants for postoperative delirium after oral and maxillofacial surgery. Results from a register-based case-control study Ortner, F. Eberl, M. Otto, S. Wang, B. Schauberger, G. Hofmann-Kiefer, K. Saller, T. J Stomatol Oral Maxillofac Surg 2020

Dementia
Dentoalveolar surgery
Oral and maxillofacial surgery
Pacu
Postoperative delirium
Tooth extraction

Investigation of Free-Flap Transfer Reconstruction in Elderly Patients and Oral Intake Function Onoda, S. Kinoshita, M. Ariyoshi, Y. J Craniofac Surg 2020
Delirium: a missing piece in the COVID-19 pandemic puzzle O'Hanlon, S. Inouye, S. K. Age Ageing 2020

Covid-19
delirium
older people

Effects of Ramelteon on the Prevention of Postoperative Delirium in Older Patients Undergoing Orthopedic Surgery: The RECOVER Randomized Controlled Trial Oh, E. S. Leoutsakos, J. M. Rosenberg, P. B. Pletnikova, A. M. Khanuja, H. S. Sterling, R. S. Oni, J. K. Sieber, F. E. Fedarko, N. S. Akhlaghi, N. Neufeld, K. J. Am J Geriatr Psychiatry 2020

Delirium
melatonin receptor agonist
orthopedic surgery
ramelteon

A roadmap to advance delirium research: Recommendations from the NIDUS Scientific Think Tank Oh, E. S. Akeju, O. Avidan, M. S. Cunningham, C. Hayden, K. M. Jones, R. N. Khachaturian, A. S. Khan, B. A. Marcantonio, E. R. Needham, D. M. Neufeld, K. J. Rose, L. Spence, J. Tieges, Z. Vlisides, P. Inouye, S. K. Alzheimers Dement 2020

biomarkers
definition
delirium
dementia
diagnosis
measurement
pathophysiology
prevention
public health campaign
treatment

Association between a prognostic nutritional index less than 50 and the risk of medical complications after adult spinal deformity surgery Oe, S. Yamato, Y. Hasegawa, T. Yoshida, G. Kobayashi, S. Yasuda, T. Banno, T. Arima, H. Mihara, Y. Ushirozako, H. Yamada, T. Ide, K. Watanabe, Y. Matsuyama, Y. J Neurosurg Spine 2020

ASD = adult spinal deformity
AUC = area under the curve
BMI = body mass index
C7-CSVL = C7 plumb line to the central sacral vertical line
CCI = Charlson Comorbidity Index
CL = cervical lordosis
DVT = deep venous thrombosis
LL = lumbar lordosis
PE = pulmonary embolism
PI = pelvic incidence
PNI = prognostic nutritional index
PT = pelvic tilt
ROC = receiver operating characteristic
SSI = surgical site infection
SVA = sagittal vertical axis
TK = thoracic kyphosis
TS = T1 slope
adult spinal deformity
delirium
malnutrition
medical complications
nutritional status
prognostic nutritional index

Communication with patients in post-traumatic confusional state: perception of rehabilitation staff Nielsen, A. I. Power, E. Jensen, L. R. Brain Injury 2020

comprehension
confusion
content analysis
cross-sectional study
health personnel attitude
human
interpersonal communication
medical staff
neurorehabilitation
open-ended questionnaire
professional-patient relationship
rehabilitation center
review
traumatic brain injury
verbal communication

Singapore SPICE: Sedation practices in intensive care evaluation in Singapore - A prospective cohort study of the public healthcare system Ng, S. Y. Phua, J. Wong, Y. L. Kalyanasundaram, G. Mukhopadhyay, A. Lim, D. Chia, N. Ho, B. C. H. Bailey, M. J. Shehabi, Y. Ti, L. K. Singapore Medical Journal 2020

dexmedetomidine
diazepam
fentanyl
haloperidol
ketamine
midazolam
morphine
propofol
anesthesia level
artificial ventilation
clinical trial
cohort analysis
controlled study
critically ill patient
delirium
endotracheal intubation
hospital discharge
hospital mortality
human
incidence
intensive care
length of stay
major clinical study
mortality
multicenter study
neurologic disease
outcome assessment
practice guideline
prospective study
public health
review
Richmond Agitation Sedation Scale
sedation
Singapore

Association of obstructive sleep apnea and postoperative cardiac complications: A systematic review and meta-analysis with trial sequential analysis Ng, K. T. Lee, Z. X. Ang, E. Teoh, W. Y. Wang, C. Y. J Clin Anesth 2020

Cardiac complications
Meta-analysis
Mortality
Obstructive sleep apnea
Oximetry
Sleep study

Long-term mortality in very old patients with cancer admitted to intensive care unit: A retrospective cohort study Nassar Junior, A. P. Trevisani, M. D. S. Bettim, B. B. Caruso, P. J Geriatr Oncol 2020

Aged 80 and over
Cancer
Critical care
Decision making
Mortality

Functional Outcomes of Frail Patients after Cardiac Surgery: An Observational Study Nakano, M. Nomura, Y. Suffredini, G. Bush, B. Tian, J. Yamaguchi, A. Walston, J. Hasan, R. Mandal, K. Schena, S. Hogue, C. W. Brown, C. H. Anesthesia and Analgesia 2020

adult
article
complication
controlled study
daily life activity
delirium
EuroSCORE
female
frailty
functional status
gender
heart surgery
hospitalization
human
major clinical study
male
observational study
prevalence
propensity score
race
risk assessment
surgery
surgical risk

Development of a clinical score, PANDA, to predict delirium in stroke care unit Nakamizo, T. Kanda, T. Kudo, Y. Sugawara, E. Hashimoto, E. Okazaki, A. Usuda, M. Nagai, T. Hara, H. Johkura, K. J Neurol Sci 2020

Area under curve
Clinical decision rules
Clinical nursing research
Delirium
Sensitivity and specificity
Sleep deprivations
Stroke care unit

Impact of Tobacco Smoking on Outcomes after Posterior Decompression Surgery in Patients with Cervical Spondylotic Myelopathy: A Retrospective Multicenter Study Nagoshi, N. Kono, H. Tsuji, O. Aoyama, R. Fujiyoshi, K. Shiono, Y. Ishikawa, M. Daimon, K. Hosogane, N. Takeuchi, A. Okada, E. Fujita, N. Yagi, M. Nakamura, M. Matsumoto, M. Watanabe, K. Ishii, K. Yamane, J. Clinical Spine Surgery 2020

adult
article
attention
case control study
cervical spondylotic myelopathy
clinical evaluation
complication
controlled study
decompression surgery
demography
ex-smoker
female
follow up
hematoma
human
Japan
Japanese Orthopaedic Association score
laminectomy
laminoplasty
liquorrhea
major clinical study
male
multicenter study
neck pain
non-smoker
paralysis
peroperative complication
postoperative delirium
preoperative evaluation
retrospective study
smoking cessation
surgery
surgical infection
visual analog scale

Role of omega-3 fatty acids in the prevention of delirium in mechanically ventilated patients Naghibi, T. Shafigh, N. Mazloomzadeh, S. Journal of Research in Medical Sciences 2020

IRCT2015095536N5
haloperidol
omega 3 fatty acid
adult
agitation
APACHE
article
artificial ventilation
clinical outcome
confusion
Confusion Assessment Method
controlled study
delirium
double blind procedure
female
Glasgow coma scale
human
intensive care unit
length of stay
major clinical study
male
mental disease assessment
middle aged
mortality
outcome assessment
randomized controlled trial
Richmond Agitation Sedation Scale

Brain BOLD MRI O(2) and CO(2) stress testing: implications for perioperative neurocognitive disorder following surgery Mutch, W. A. C. El-Gabalawy, R. Ryner, L. Puig, J. Essig, M. Kilborn, K. Fidler, K. Graham, M. R. Crit Care 2020

Anesthesia
Bold
Co2
Cognitive dysfunction
Critical care
Delirium
Mri
Mechanical ventilation
O2

Off-label use of quetiapine in nursing homes: Does medical specialty of prescribing physicians play a role? Müller, L. Noseda, R. Bertoli, R. Bissig, M. Ceschi, A. British Journal of Clinical Pharmacology 2020

quetiapine
anxiety disorder
delirium
dementia
depression
human
insomnia
letter
major clinical study
medical specialist
nursing home
physician
prescription
priority journal
Switzerland

Multidisciplinary quality improvement programme for older patients admitted to a vascular surgery ward() Mudge, A. M. McRae, P. Donovan, P. J. Reade, M. C. Intern Med J 2020

delirium
functional decline
length of hospital stay
patient care team
vascular surgery

Cross-cultural adaptation and validation of the 3D-CAM Chinese version in surgical ICU patients Mu, D. L. Ding, P. P. Zhou, S. Z. Liu, M. J. Sun, X. Y. Li, X. Y. Wang, D. X. BMC Psychiatry 2020

3d-cam
Chinese version, validation, Chinese
Delirium
Diagnosis
Screening tool

Thiamine for Prevention of Postoperative Delirium in Patients Undergoing Gastrointestinal Surgery: A Randomized Clinical Trial Moslemi, R. Khalili, H. Mohammadi, M. Mehrabi, Z. Mohebbi, N. J Res Pharm Pract 2020

Delirium
Thiamine
gastrointestinal surgery

How successful are we in relieving terminal dyspnea in cancer patients? A real-world multicenter prospective observational study Mori, M. Morita, T. Matsuda, Y. Yamada, H. Kaneishi, K. Matsumoto, Y. Matsuo, N. Odagiri, T. Aruga, E. Watanabe, H. Tatara, R. Sakurai, H. Kimura, A. Katayama, H. Suga, A. Nishi, T. Shirado, A. N. Watanabe, T. Kuchiba, A. Yamaguchi, T. Iwase, S. Supportive Care in Cancer 2020
Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia Morandi, A. Zambon, A. Di Santo, S. G. Mazzone, A. Cherubini, A. Mossello, E. Bo, M. Marengoni, A. Bellelli, G. Journal of the American Medical Directors Association 2020

intravenous catheter
urinary catheter
antibiotic agent
antilipemic agent
antithrombocytic agent
cholinesterase inhibitor
hydroxymethylglutaryl coenzyme A reductase inhibitor
memantine
neuroleptic agent
aged
article
cross-sectional study
delirium
dementia
female
hospitalization
human
Italy
major clinical study
male
medical record
prescription
prevalence
very elderly

Infection in older adults: a qualitative study of patient experience Moore, A. McKelvie, S. Glogowska, M. Lasserson, D. Hayward, G. Br J Gen Pract 2020

aged
frail elderly
infection
qualitative research

Aripiprazole for prevention of delirium in the neurosurgical intensive care unit: a double-blind, randomized, placebo-controlled study Mokhtari, M. Farasatinasab, M. Jafarpour Machian, M. Yaseri, M. Ghorbani, M. Ramak Hashemi, S. M. Nikoobakht, M. Golchin, N. Mohammadi, G. Sistanizad, M. Eur J Clin Pharmacol 2020

Aripiprazole
Delirium
Delirium prevention
Icu

Potentially Inappropriate Medications in a Psychogeriatric Inpatient Ward: An Audit Based on Beers Criteria Moebs, I. Abeln, E. Siefert, A. Barak, Y. Neurology and Therapy 2020

adult
aged
anxiety
article
attention deficit disorder
bipolar disorder
clinical audit
clinical decision making
delirium
depression
drug dependence
female
generalized anxiety disorder
gerontopsychiatry
human
major clinical study
male
medication compliance
mental disease
personality disorder
posttraumatic stress disorder
prescription
priority journal
psychiatry
psychosis
retrospective study
schizophrenia
very elderly

An 11-year review of hip fracture hospitalisations, health outcomes, and predictors of access to in-hospital rehabilitation for adults ≥ 65 years living with and without dementia: a population-based cohort study Mitchell, R. Draper, B. Brodaty, H. Close, J. Ting, H. P. Lystad, R. Harris, I. Harvey, L. Sherrington, C. Cameron, I. D. Braithwaite, J. Osteoporos Int 2020

Aged care
Dementia
Frailty
Hip fracture
Rehabilitation

Evaluation of a co-produced delirium awareness programme for undergraduate nursing students in Northern Ireland: a pre-test/post-test study Mitchell, G. McVeigh, C. Carlisle, S. Brown-Wilson, C. BMC Nurs 2020

Co-design
Co-production
Delirium
Nurse education
Nursing
Nursing student

Perioperative dexmedetomidine and postoperative delirium in non-cardiac surgery: a meta-analysis Ming, S. Zhang, X. Gong, Z. Xie, Y. Xie, Y. Ann Palliat Med 2020

Dexmedetomidine
meta-analysis
postoperative delirium
surgery

Cholinesterases and Anticholinergic Medications in Postoperative Pediatric Delirium Meyburg, J. Ritsert, M. L. Traube, C. Plaschke, K. von Haken, R. Pediatr Crit Care Med 2020
Comparison of novel tools with traditional cognitive tests in detecting delirium in elderly medical patients Meagher, D. J. O'Connell, H. Leonard, M. Williams, O. Awan, F. Exton, C. Tenorio, M. O'Connor, M. Dunne, C. P. Cullen, W. McFarland, J. Adamis, D. World J Psychiatry 2020

Assessment
Attention
Delirium
Dementia
Letter and Shape Drawing test
Lighthouse test
Phenomenology
Vigilance
Visuospatial function

A systematic review and meta-analysis of the accuracy of the clock drawing test (CDT) in the identification of delirium in older hospitalised patients Meagher, D. Williams, O. A. O'Connell, H. Leonard, M. Cullen, W. Dunne, C. P. Mulligan, O. Adamis, D. Aging & mental health 2020

adult
aged
article
Cinahl
clock drawing test
cognitive defect
diagnosis
diagnostic test accuracy study
Embase
female
hospital patient
human
male
Medline
meta analysis
Mini Mental State Examination
Preferred Reporting Items for Systematic Reviews and Meta-Analyses
PsycINFO
Scopus
sensitivity and specificity
software
systematic review

Family intervention improves outcomes for patients with delirium: Systematic review and meta-analysis McKenzie, J. Joy, A. Australas J Ageing 2020

caregivers
delirium
family
length of stay

Effectiveness and Safety of Intrathecal Ziconotide: Final Results of the Patient Registry of Intrathecal Ziconotide Management (PRIZM) McDowell, G. C. Saulino, M. F. Wallace, M. Grigsby, E. J. Rauck, R. L. Kim, P. Vanhove, G. F. Ryan, R. Huang, I. Z. Deer, T. Pain medicine (Malden, Mass.) 2020

adult
analgesia
article
chronic pain
clinical practice
confusion
controlled study
dizziness
drug safety
female
human
major clinical study
male
multicenter study
nausea
numeric rating scale
observational study
outcome assessment
pharmacokinetics
prescription
prospective study
omega conotoxin MVIIA

Management Effort for Delirium and Insomnia in Patients with Acute Ischemic Stroke (MEDIAS) Study Matsuzono, K. Mashiko, T. Ozawa, T. Miura, K. Suzuki, M. Furuya, K. Ozawa, M. Anan, Y. Shimazaki, H. Koide, R. Tanaka, R. Fujimoto, S. Psychiatry Clin Neurosci 2020
High Prevalence of Oropharyngeal Dysphagia in Acutely Hospitalized Patients Aged 80 Years and Older Mateos-Nozal, J. Montero-Errasquín, B. Sánchez García, E. Romero Rodríguez, E. Cruz-Jentoft, A. J. J Am Med Dir Assoc 2020

Dysphagia
acute geriatric unit
deglutition disorders
older
prevalence
risk factors

Dexmedetomidine in medical cardiac intensive care units. Data from a multicenter prospective registry Mateos Gaitan, R. Vicent, L. Rodriguez-Queralto, O. Lopez-de-Sa, E. Elorriaga, A. Pastor, G. Bañeras, J. Lorenzo, B. García-Rubira, J. C. Corbi, M. Ariza, A. Martínez-Sellés, M. Int J Cardiol 2020

Adverse effects
Cardiac intensive care unit
Dexmedetomidine
Mechanical ventilation weaning
Safety
Sedation

Myocardial Function in Patients With Radiation-Associated Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement: A Layer-Specific Strain Analysis Study Martinez, C. Cicenia, M. Sprynger, M. Postolache, A. Ilardi, F. Dulgheru, R. Radermecker, M. Esposito, G. Marechal, P. Marechal, V. Donis, N. Tridetti, J. Nguyen Trung, M. L. Sugimoto, T. Tsugu, T. Go, Y. Y. Coisne, A. Montaigne, D. Fattouch, K. Nchimi, A JACC: Cardiovascular Imaging 2020

CoreValve self-expandable biologic prosthesis
percutaneous aortic valve bioprosthesis
brain natriuretic peptide
aortic regurgitation
aortic valve stenosis
cancer radiotherapy
cardiovascular risk
cerebrovascular accident
delirium
disease risk assessment
echocardiography
heart function
heart left ventricle contraction
heart left ventricle ejection fraction
human
letter
major clinical study
paravalvular leak
priority journal
radiation sickness
retrospective study
transcatheter aortic valve implantation

Prevalence and clinical correlates of non-convulsive status epilepticus in elderly patients with acute confusional state: A systematic literature review Manfredonia, F. Saturno, E. Lawley, A. Gasverde, S. Cavanna, A. E. J Neurol Sci 2020

Acute confusional state
Elderly
Electroencephalography
Non-convulsive status epilepticus

Downstream consequences of abnormal cognitive screening in older adults seen pretreatment in a geriatric oncology clinic Malik, U. Alam, Z. Loucks, A. Jin, R. Yokom, D. Watt, S. Berger, A. Romanovsky, L. Puts, M. Alibhai, S. M. H. J Geriatr Oncol 2020

Cognitive impairment
Comprehensive geriatric assessment
Geriatric oncology
Geriatric oncology clinic
Treatment decision-making

A Study of the Psychometric Properties of the "Stanford Proxy Test for Delirium" (S-PTD): A New Screening Tool for the Detection of Delirium Maldonado, J. R. Sher, Y. I. Benitez-Lopez, M. A. Savant, V. Garcia, R. Ament, A. De Guzman, E. Psychosomatics 2020

S-ptd
Stanford Proxy Test for Delirium
delirium
screening tools

Family Identification of Delirium in the Emergency Department in Patients With and Without Dementia: Validity of the Family Confusion Assessment Method (FAM-CAM) Mailhot, T. Darling, C. Ela, J. Malyuta, Y. Inouye, S. K. Saczynski, J. J Am Geriatr Soc 2020

Fam-cam
delirium
dementia
emergency department
family caregivers

Frailty Is Associated With Postoperative Delirium But Not With Postoperative Cognitive Decline in Older Noncardiac Surgery Patients Mahanna-Gabrielli, E. Zhang, K. Sieber, F. E. Lin, H. M. Liu, X. Sewell, M. Deiner, S. G. Boockvar, K. S. Anesth Analg 2020

Aged
Cognition
Cognition Disorders/ prevention & control
Data Interpretation, Statistical
Delirium/ complications
Elective Surgical Procedures/ adverse effects
Electroencephalography
Female
Follow-Up Studies
Frail Elderly
Frailty/ complications
Geriatric Assessment
Humans
Male
Mental Recall
Neuropsychological Tests
Postoperative Cognitive Complications
Postoperative Complications/prevention & control
Prospective Studies
Risk Factors
Severity of Illness Index
Surveys and Questionnaires

2019-NCoV: What every neurologist should know? Mahajan, N. Singla, M. Singh, B. Sajja, V. Bansal, P. Paul, B. Goel, P. Midha, R. Bansal, R. Singh, G. Annals of Indian Academy of Neurology 2020

alanine aminotransferase
aspartate aminotransferase
C reactive protein
altered state of consciousness
brain disease
brain hemorrhage
brain ischemia
cerebral sinus thrombosis
cerebrovascular accident
cerebrovascular disease
China
coronavirus disease 2019
delirium
dementia
disease predisposition
dizziness
dyspnea
febrile convulsion
fever
Guillain Barre syndrome
headache
human
hypogeusia
hyposmia
intensive care unit
multiple sclerosis
myalgia
neurologic disease
neurologist
nonhuman
reverse transcription polymerase chain reaction
review
Severe acute respiratory syndrome coronavirus 2

Age, Comorbidities and Fear of Fall: mortality predictors associated with fall-related fractures Magdalini, V. Petros, I. Constantinos, T. Garyfalia, S. P. Emmanouil, P. Christos, K. George, K. Kalliopi, A. George, S. Symeon, H. P. Maedica (Buchar) 2020
Stress-Induced Behavioral Quiescence and Abnormal Rest-Activity Rhythms During Critical Illness Maas, M. B. Lizza, B. D. Kim, M. Abbott, S. M. Gendy, M. Reid, K. J. Zee, P. C. Crit Care Med 2020
Incidence and risk factors of delirium in icu patients Ma, W. Zheng, J. Xu, S. Huo, Z. International Journal of Clinical and Experimental Medicine 2020

stomach tube
calcium
protein
urea
adult
APACHE
article
artificial ventilation
blood cell count
cerebrovascular disease
delirium
disease severity
female
human
hypoxemia
incidence
infection
information processing
intensive care unit
leukocyte count
lung disease
major clinical study
male
middle aged
Richmond Alertness Sedation Scale score
risk factor
sleep disorder
visual analog scale

Age, preoperative higher serum cortisol levels, and lower serum acetylcholine levels predict delirium after percutaneous coronary intervention in acute coronary syndrome patients accompanied with renal dysfunction Ma, J. Fan, M. Wang, Z. Indian Journal of Psychiatry 2020

IE33
real time ultrasound scanner
4 aminobutyric acid
acetylcholine
creatinine
dopamine
hydrocortisone
interleukin 6
serotonin
acetylcholine blood level
acute coronary syndrome
adult
age
aged
article
blood level
blood sampling
clinical article
cohort analysis
controlled study
delirium
female
heart left ventricle ejection fraction
human
hydrocortisone blood level
incidence
kidney disease
male
middle aged
percutaneous coronary intervention
preoperative period
prospective study
questionnaire
risk factor
self report
urea nitrogen blood level
very elderly

Non-Pharmacologic Multicomponent Interventions Preventing Delirium in Hospitalized People Ludolph, P. Stoffers-Winterling, J. Kunzler, A. M. Rösch, R. Geschke, K. Vahl, C. F. Lieb, K. J Am Geriatr Soc 2020

delirium
multicomponent interventions
non-pharmacologic interventions
prevention

Usefulness of postoperative serum translocator protein as a predictive marker for delirium after breast cancer surgery in elderly women Lu, G. W. Chou, Y. E. Jin, W. L. Su, X. B. J Int Med Res 2020

Translocator protein
breast cancer
delirium
elderly
inflammation
surgery

Characteristics, Symptom Management, and Outcomes of 101 Patients With COVID-19 Referred for Hospital Palliative Care Lovell, N. Maddocks, M. Etkind, S. N. Taylor, K. Carey, I. Vora, V. Marsh, L. Higginson, I. J. Prentice, W. Edmonds, P. Sleeman, K. E. J Pain Symptom Manage 2020

Covid-19
coronavirus
end of life
hospice
palliative care
symptom management

Characterisation of ICU sleep by a commercially available activity tracker and its agreement with patient-perceived sleep quality Louzon, P. Andrews, J. Torres, X. Pyles, E. Ali, M. Du, Y. Devlin, J. BMJ Open Respir Res 2020

equipment evaluations

Surgical treatment of hip fracture in centenarians: Complications and independent risk factors of death López, Torres, II Sanz-Ruiz, P. Montero-Fernández, N. Chana, F. Serra-Rexach, J. A. Benjumea-Carrasco, A. Vaquero-Martín, J. Injury 2020

Centenarians
Hip fracture
Risk factors
Surgery: Mortality

Long-term survival of femoral neck fracture patients aged over ninety years: Arthroplasty compared with nonoperative treatment Liu, Y. Zhang, C. W. Zhao, X. D. BMC Musculoskeletal Disorders 2020

albumin
aged
albumin blood level
arthroplasty
article
clinical effectiveness
comparative effectiveness
conservative treatment
controlled study
decubitus
delirium
elderly care
female
femoral neck fracture
geriatric patient
hematocrit
human
long term survival
major clinical study
male
mortality rate
outcome assessment
retrospective study
survival analysis
survival rate
survival time
very elderly

Subjective memory complaints predict poorer functional recovery during the first year following hip-fracture surgery among elderly adults Liu, H. Y. Wang, H. P. Chen, C. Y. Wu, C. C. Hua, M. S. Lin, Y. E. Lin, Y. C. Shyu, Y. L. Int J Geriatr Psychiatry 2020

hip fracture
postoperative
recovery outcomes
subjective memory complaints

Delirium Severity Trajectories and Outcomes in ICU Patients: Defining a Dynamic Symptom Phenotype Lindroth, H. Khan, B. A. Carpenter, J. S. Gao, S. Perkins, A. J. Khan, S. H. Wang, S. Jones, R. N. Boustani, M. A. Ann Am Thorac Soc 2020
Early mobilisation of ventilated patients in the intensive care unit: A survey of critical care clinicians in an Australian tertiary hospital Lin, F. Phelan, S. Chaboyer, W. Mitchell, M. Aust Crit Care 2020

Attitudes
Barriers
Behaviour research
Early mobilisation
Intensive care unit
Knowledge translation
Perception
Questionnaire

Perioperative Dexmedetomidine Supplement Decreases Delirium Incidence After Adult Cardiac Surgery: A Randomized, Double-Blind, Controlled Study Likhvantsev, V. V. Landoni, G. Grebenchikov, O. A. Ovezov, A. M. Skripkin, Y. V. Lembo, R. Gaevskiy, D. I. Tereshina, A. A. Yavorovskiy, A. G. Journal of Cardiothoracic and Vascular Anesthesia 2020

adult
article
cardiopulmonary bypass
clinical trial
controlled study
coronary artery bypass graft
double blind procedure
drug therapy
female
general anesthesia
human
incidence
intensive care unit
length of stay
major clinical study
male
mortality
operating room
postoperative delirium
randomized controlled trial
surgery
university hospital
valve
dexmedetomidine
placebo
sevoflurane

Derivation and Validation of a Risk Stratification System for Predicting Postoperative Cognitive Impairment Liao, Y. Su, X. Ouyang, W. Li, L. Chen, S. Chou, J. Le, Y. J Invest Surg 2020

Postoperative cognitive dysfunction
elderly patients
non-cardiac surgery
risk stratification system

Effects of anesthesia depth on postoperative cognitive function and inflammation: a systematic review and meta-analysis Li, Y. Zhang, B. Minerva Anestesiol 2020
Prevalence, outcome and prognostic factors of neuropsychiatric systemic lupus erythematosus: A real world single center study Li, X. Xiang, X. Sun, J. Liu, S. Liu, Y. Feng, L. Li, C. Li, Z. Mod Rheumatol 2020

Neuropsychiatric systemic lupus erythematosus
causes of death
prognostic factors
standardized mortality ratio
survival

Postoperative Delirium Following Joint Replacement in Patients With Dementia in New South Wales, Australia: A State-Wide Retrospective Cohort Study Li, X. Du, W. Parkinson, A. Glasgow, N. Research in gerontological nursing 2020

adult
article
cohort analysis
comorbidity
controlled study
dementia
female
geriatric nursing
hospital volume
human
incidence
male
New South Wales
patient coding
postoperative delirium
replacement arthroplasty
retrospective study

Effect of dexmedetomidine on prevention of postoperative nausea and vomiting in pediatric strabismus surgery: a randomized controlled study Li, S. Liu, T. Xia, J. Jia, J. Li, W. BMC Ophthalmol 2020

Dexmedetomidine
Emergence agitation
Oculocardiac reflex
Postoperative nausea and vomiting
Strabismus surgery

Toxicity and survival outcomes of autologous stem cell transplant in multiple myeloma patients with renal insufficiency: an institutional comparison between two eras Li, A. Y. Atenafu, E. G. Bernard, R. S. Masih-Khan, E. Reece, D. Franke, N. Tiedemann, R. Prica, A. Trudel, S. Kukreti, V. Chen, C. I. Bone Marrow Transplant 2020
Risk Prediction for Adverse Outcomes for Frail Older Persons with Complex Healthcare and Social Care Needs Admitted to a Community Virtual Ward Model Lewis, C. O'Caoimh, R. Patton, D. O'Connor, T. Moore, Z. Nugent, L. E. Clin Interv Aging 2020

case management
community virtual ward
complex care
health states
older persons
risk prediction

The role of melatonin and melatonin receptor agonist in the prevention of sleep disturbances and delirium in intensive care unit - a clinical review Lewandowska, K. Małkiewicz, M. A. Siemiński, M. Cubała, W. J. Winklewski, P. J. Mędrzycka-Dąbrowska, W. A. Sleep Med 2020

Delirium
Icu
Melatonin
Ramelteon
Sleep

Neurological manifestations associated with COVID-19: a review and a call for action Leonardi, M. Padovani, A. McArthur, J. C. Journal of Neurology 2020

acroparesthesia
acute disease
allodynia
altered state of consciousness
anosmia
ataxia
brain disease
brain hemorrhage
brain ischemia
central nervous system
cerebrovascular accident
clinical feature
consciousness disorder
coronavirus disease 2019
cytokine storm
delirium
disease course
disease predisposition
disease severity
dizziness
dysarthria
dysgeusia
electroencephalogram
encephalitis
Guillain Barre syndrome
headache
human
hypogeusia
hyposmia
muscle injury
myalgia
neurologic disease
paresthesia
peripheral nervous system
priority journal
research priority
respiratory failure
review
rhabdomyolysis
risk factor
seizure
systematic review

"You've got to keep moving, keep going": Understanding older patients' experiences and perceptions of delirium and nonpharmacological delirium prevention strategies in the acute hospital setting Lee-Steere, K. Liddle, J. Mudge, A. Bennett, S. McRae, P. Barrimore, S. E. J Clin Nurs 2020

adult
awareness
caregivers
delirium
exercise
inpatients
perception
qualitative research

The effect of dexmedetomidine on postoperative behaviour change in children: a randomised controlled trial Lee-Archer, P. F. von Ungern-Sternberg, B. S. Reade, M. Betts, M. Haenke, D. Keys, A. Rance, T. Gibbons, K. Long, D. Anaesthesia 2020

behaviour changes
children
dexmedetomidine
emergence delirium
paediatrics

Developing delirium best practice: a systematic review of education interventions for healthcare professionals working in inpatient settings Lee, S. Y. Fisher, J. Wand, A. P. F. Milisen, K. Detroyer, E. Sockalingam, S. Agar, M. Hosie, A. Teodorczuk, A. European Geriatric Medicine 2020

behavior change
delirium
health care personnel
hospital care
hospital patient
human
intensive care unit
learning
length of stay
palliative therapy
patient care
patient education
priority journal
review
staff training
systematic review
treatment outcome

Outcomes of the Extreme Elderly Undergoing Anaesthesia and Surgery amongst Southeast Asians Lee, S. J. Ng, O. Thong, S. Y. Anesthesiology Research and Practice 2020

dynamic hip screw
anesthetic agent
atracurium besilate
bupivacaine
desflurane
ephedrine
fentanyl
glycopyrronium
ketamine
midazolam
morphine
neostigmine
paracetamol
pethidine
phenylephrine
propofol
rocuronium
sevoflurane
aged
anesthesia
article
critical limb ischemia
cystoscopy
elective surgery
embolectomy
emergency surgery
female
general anesthesia
general surgery
geriatric patient
heart arrhythmia
hernioplasty
hip surgery
hospital readmission
human
hypertension
hypotension
hypothermia
inguinal hernia
ischemic heart disease
length of stay
major clinical study
male
medical record review
mortality
neck dissection
orthopedic surgery
outcome assessment
pneumonia
postoperative complication
postoperative delirium
postoperative hemorrhage
postoperative nausea and vomiting
practice guideline
regional anesthesia
reoperation
retrospective study
sepsis
Southeast Asian
spinal anesthesia
surgery
surgical infection
transthoracic echocardiography
urinary tract infection
urologic surgery
vascular surgery
venous thromboembolism
very elderly

Predictors of New-Onset Physical Restraint Use in Critically Ill Adults Lawson, T. N. Tan, A. Thrane, S. E. Happ, M. B. Mion, L. C. Tate, J. Balas, M. C. Am J Crit Care 2020
Decision-making for older patients undergoing emergency laparotomy: defining patient and clinician values and priorities Law, J. Welch, C. Javanmard-Emamghissi, H. Clark, M. Bisset, C. N. O'Neil, P. Moug, S. J. Colorectal Dis 2020

Emergency laparotomy
decision-making
morbidity
mortality
older adult
patient perspective

Delirium prevalence and prevention in patients with acute brain injury: A prospective before-and-after intervention study Larsen, L. K. Møller, K. Petersen, M. Egerod, I. Intensive & critical care nursing 2020

adult
article
brain injury
case report
checklist
clinical article
Denmark
female
human
intensive care nursing
intensive care psychosis
intervention study
length of stay
male
mortality
neurological intensive care unit
neuroscience nursing
outcome assessment
pain
prevalence
prevention
prospective study
sedation
sleep
university hospital

Comparison of Hydromorphone versus Fentanyl-based Sedation in Extracorporeal Membrane Oxygenation: A Propensity-Matched Analysis Landolf, K. M. Rivosecchi, R. M. Goméz, H. Sciortino, C. M. Murray, H. N. Padmanabhan, R. R. Sanchez, P. G. Harano, T. Sappington, P. L. Pharmacotherapy 2020

acute respiratory distress syndrome
delirium
extracorporeal membrane oxygenation
intensive care
sedation

Collaborative Delirium Prevention in the Age of COVID-19 LaHue, S. C. James, T. C. Newman, J. C. Esmaili, A. M. Ormseth, C. H. Ely, E. W. J Am Geriatr Soc 2020

Aged
Cooperative Behavior
Coronavirus Infections/ epidemiology
Delirium/epidemiology/ prevention & control
Humans
Pandemics
Pneumonia, Viral/ epidemiology
United States/epidemiology

Intra-operative hyperoxia and the risk of delirium in elderly patients after cardiac surgery Kupiec, A. Adamik, B. Forkasiewicz-Gardynik, K. Goździk, W. Aging (Albany NY) 2020

cardiac surgery
cardiopulmonary bypass
delirium
elderly
hyperoxia
interest

Clinical profile and predictor of adverse outcome in children with acute encephalitis syndrome: A cross-sectional study Kuntal, M. Swarnkar, K. Journal of Krishna Institute of Medical Sciences University 2020

immunoglobulin M
nonstructural protein 1
acute disease
adolescent
article
artificial ventilation
child
clinical feature
clinical outcome
coma
confusion
convulsion
cross-sectional study
demography
dengue
disorientation
encephalitis
female
fever
headache
human
liver function test
major clinical study
malaria
male
mental health
mortality
neurocysticercosis
neuroimaging
observational study
papilledema
risk factor
seizure
sensory system
shock
thrombocytopenia
tuberculosis
virus encephalitis
vomiting

Intraoperative Optimization of Both Depth of Anesthesia and Cerebral Oxygenation in Elderly Patients Undergoing Coronary Artery Bypass Graft Surgery-A Randomized Controlled Pilot Trial Kunst, G. Gauge, N. Salaunkey, K. Spazzapan, M. Amoako, D. Ferreira, N. Green, D. W. Ballard, C. J Cardiothorac Vasc Anesth 2020

cardiac anesthesia
cerebral oximetry
cognitive function
delirium
depth of anesthesia monitoring

Establishment of an enhanced recovery after surgery protocol in minimally invasive heart valve surgery Kubitz, J. C. Schulte-Uentrop, L. Zoellner, C. Lemke, M. Messner-Schmitt, A. Kalbacher, D. Sill, B. Reichenspurner, H. Koell, B. Girdauskas, E. PLoS One 2020
Preoperative cognitive impairment associated with oversedation during recovery from anesthesia Kruthiventi, S. C. Laporta, M. L. Deljou, A. Knopman, D. S. Petersen, R. C. Schroeder, D. R. Sprung, J. Weingarten, T. N. J Anesth 2020

Anesthesia
Delirium
Dementia
Mild cognitive impairment
Over sedation
Surgery

Non-contact monitoring of agitation and use of a sheltering device in patients with dementia in emergency departments: a feasibility study Kroll, L. Böhning, N. Müßigbrodt, H. Stahl, M. Halkin, P. Liehr, B. Grunow, C. Kujumdshieva-Böhning, B. Freise, C. Hopfenmüller, W. Friesdorf, W. Jockers-Scherübl, M. Somasundaram, R. BMC Psychiatry 2020

Dementia, agitation
Emergency department
Geriatric care
Non-contact monitoring

COVID-19: ICU delirium management during SARS-CoV-2 pandemic Kotfis, K. Williams Roberson, S. Wilson, J. E. Dabrowski, W. Pun, B. T. Ely, E. W. Crit Care 2020

Betacoronavirus
Coronavirus Infections/ complications/epidemiology
Delirium/etiology/ therapy
Humans
Intensive Care Units
Pandemics
Pneumonia, Viral/ complications/epidemiology
Safety
Covid-19
Delirium
Pics
Ptsd
Pain
Pandemic
SARS-CoV-2
Sedation

COVID-19: What do we need to know about ICU delirium during the SARS-CoV-2 pandemic? Kotfis, K. Williams Roberson, S. Wilson, J. Pun, B. Ely, E. W. Jeżowska, I. Jezierska, M. Dabrowski, W. Anaesthesiol Intensive Ther 2020

Pics
Ptsd
SARS-CoV-2
coronavirus
delirium
pain
pandemic
sedation
Covid-19

The impact of acute kidney injury in the perioperative period on the incidence of postoperative delirium in patients undergoing coronary artery bypass grafting—observational cohort study Kotfis, K. Ślozowska, J. Listewnik, M. Szylińska, A. Rotter, I. International Journal of Environmental Research and Public Health 2020

creatinine
acute kidney failure
age
aged
article
cohort analysis
Confusion Assessment Method for Intensive Care Unit
controlled study
coronary artery bypass graft
creatinine blood level
EuroSCORE
female
human
incidence
kidney function
major clinical study
male
mortality
neurologic disease assessment
observational study
perioperative period
postoperative delirium
prognosis
renal replacement therapy
retrospective study
risk factor

Association between Preoperative Obstructive Sleep Apnea and Preoperative Positive Airway Pressure with Postoperative Intensive Care Unit Delirium King, C. R. Fritz, B. A. Escallier, K. Ju, Y. E. S. Lin, N. McKinnon, S. Avidan, M. S. Palanca, B. J. JAMA Network Open 2020

adult
airway pressure
article
attributable risk
blood pressure
body mass
cohort analysis
controlled study
fatigue
female
gender
general anesthesia
human
intensive care unit
major clinical study
major surgery
male
measurement error
neck circumference
postoperative delirium
preoperative evaluation
questionnaire
retrospective study
risk assessment
selection bias
sensitivity analysis
sleep disordered breathing
snoring
surgery
tertiary care center
validity

Risk factors and outcomes of sepsis-associated delirium in intensive care unit patients: A secondary data analysis Kim, Y. Jin, Y. Jin, T. Lee, S. M. Intensive Crit Care Nurs 2020

Delirium
Risk factors
Sepsis
Sepsis-associated encephalopathy
Treatment outcome

Factors affecting the post-anesthetic recovery score and length of stay in the recovery room in elderly patients with hypertension Kim, S. Kwon, M. Medico-Legal Update 2020

aged
airway obstruction
anesthetic recovery
article
bleeding
body temperature
cardiovascular disease
cerebrovascular disease
delirium
dementia
depression
diabetes mellitus
educational status
elective surgery
extubation
female
general anesthesia
geriatric patient
Glasgow coma scale
heart arrhythmia
heart disease
human
hypertension
kidney disease
length of stay
lung disease
major clinical study
male
malignant neoplasm
metabolic disorder
nausea and vomiting
osteoporosis
patient history of surgery
psychological aspect
recovery room
shivering
surgery
surgical patient
thyroid disease

Comparative efficacy and acceptability of pharmacological interventions for the treatment and prevention of delirium: A systematic review and network meta-analysis Kim, M. S. Rhim, H. C. Park, A. Kim, H. Han, K. M. Patkar, A. A. Pae, C. U. Han, C. J Psychiatr Res 2020

Antipsychotics
Delirium
Dexmedetomidine
Intensive care unit
Network meta-analysis
Ramelteon

Pre-operative hemoglobin level and use of sedative-hypnotics are independent risk factors for post-operative delirium following total knee arthroplasty Kijima, E. Kayama, T. Saito, M. Kurosaka, D. Ikeda, R. Hayashi, H. Kubota, D. Hyakutake, T. Marumo, K. BMC Musculoskelet Disord 2020

Anemia
Delirium
Elderly
Orthopaedic surgery
Post-operative complications
Sedative-hypnotics
Total knee arthroplasty

Decreasing Delirium Through Music: A Randomized Pilot Trial Khan, S. H. Xu, C. Purpura, R. Durrani, S. Lindroth, H. Wang, S. Gao, S. Heiderscheit, A. Chlan, L. Boustani, M. Khan, B. A. Am J Crit Care 2020
Time trends of delirium rates in the intensive care unit Khan, S. H. Lindroth, H. Hendrie, K. Wang, S. Imran, S. Perkins, A. J. Gao, S. Vahidy, F. S. Boustani, M. Khan, B. A. Heart Lung 2020

Delirium
Intensive care unit
Outcomes
Time trend

Neurological complications in recipients after living donor liver transplantation Khalil, M. Elbanhawy, I. Elsherbiny, A. Amer, H. Ahmed, S. Neurology India 2020

ammonia
bilirubin
cyclosporine
tacrolimus
adult
agitation
ammonia blood level
article
bilirubin blood level
brain disease
brain hemorrhage
brain ischemia
central pontine myelinolysis
clinical examination
cohort analysis
consciousness disorder
controlled clinical trial
controlled study
delirium
delusion
disease classification
Egypt
end stage liver disease
female
flapping tremor
graft recipient
graft rejection
hallucination
headache
hospital admission
human
human cell
incidence
intensive care unit
laboratory test
length of stay
liver transplantation
living donor
major clinical study
male
meningoencephalitis
middle aged
myopathy
neuroimaging
neurological complication
neuropathy
observational study
postoperative complication
retrospective study
seizure
side effect